Article
Oncology
Marta Farras, Enrique Almanza-Aguilera, Alvaro Hernaez, Nuria Agusti, Josep Julve, Montserrat Fito, Olga Castaner
Summary: Virgin olive oil is a key component of the Mediterranean diet, containing a variety of beneficial health compounds. Consumption of olive oil has been linked to improvements in human health and reduced risk of cancer.
SEMINARS IN CANCER BIOLOGY
(2021)
Article
Nutrition & Dietetics
Elena Formisano, Andrea Pasta, Anna Laura Cremonini, Ilaria Di Lorenzo, Samir Giuseppe Sukkar, Livia Pisciotta
Summary: The study found that higher consumption of dairy products was associated with higher cholesterol levels, while higher consumption of meat products was associated with lower HDL-C and TG levels and higher TC levels. Adherence to a Mediterranean diet significantly improved after follow-up.
Review
Nutrition & Dietetics
Giuseppina Augimeri, Francesca Ida Montalto, Cinzia Giordano, Ines Barone, Marilena Lanzino, Stefania Catalano, Sebastiano Ando, Francesca De Amicis, Daniela Bonofiglio
Summary: The traditional Mediterranean Diet, rich in bioactive compounds like polyphenols, retinoids, and PUFAs, has been shown to have beneficial effects against chronic illnesses. These compounds possess antioxidant, anti-inflammatory, and antitumoral properties, making them potential candidates for future anticancer therapeutics in breast cancer.
Article
Medicine, General & Internal
Michele Matta, Inge Huybrechts, Carine Biessy, Corinne Casagrande, Sahar Yammine, Agnes Fournier, Karina Standahl Olsen, Marco Lukic, Inger Torhild Gram, Eva Ardanaz, Maria-Jose Sanchez, Laure Dossus, Renee T. Fortner, Bernard Srour, Franziska Jannasch, Matthias B. Schulze, Pilar Amiano, Antonio Agudo, Sandra Colorado-Yohar, J. Ramon Quiros, Rosario Tumino, Salvatore Panico, Giovanna Masala, Valeria Pala, Carlotta Sacerdote, Anne Tjonneland, Anja Olsen, Christina C. Dahm, Ann H. Rosendahl, Signe Borgquist, Maria Wennberg, Alicia K. Heath, Dagfinn Aune, Julie Schmidt, Elisabete Weiderpass, Veronique Chajes, Marc J. Gunter, Neil Murphy
Summary: This study found that higher dietary intakes of trans fatty acids, especially industrial trans fatty acids, were associated with an increased risk of breast cancer among over 318,000 women. This association was consistent across menopausal status, body mass index, and breast cancer subtypes. Further mechanistic studies are needed to explore the underlying biological pathways.
Article
Nutrition & Dietetics
Danijela Ristic-Medic, Marijana Kovacic, Marija Takic, Aleksandra Arsic, Snjezana Petrovic, Marija Paunovic, Maja Jovicic, Vesna Vucic
Summary: This study evaluated the effects of calorie-restricted Mediterranean and low-fat diets on patients with NAFLD. Both diets resulted in significant weight loss and improvements in liver status and cardiometabolic markers. The Mediterranean diet may have additional benefits compared to the low-fat diet by improving fatty acid profiles and FLI in NAFLD patients.
Article
Nutrition & Dietetics
Tamiris Trevisan de Barros, Vinicius de Paula Venancio, Livia Cristina Hernandes, Lusania Maria Greggi Antunes, Elaine Hillesheim, Roberta Garcia Salomao, Mariana Giaretta Mathias, Carolina Almeida Coelho-Landell, Roseli Borges Donega Toffano, Maria Olimpia Ribeiro do Vale Almada, Jose Simon Camelo-Junior, Sofia Moco, Ornella Cominetti, Fabio da Veiga Ued, Jim Kaput, Jacqueline Pontes Monteiro
Summary: This study aimed to explore differences in proteomic profiles for individuals with different DNA damage and EPA/DHA levels, finding that low levels of n-3 long-chain PUFA may have a less protective role against DNA damage through the expression of pro-inflammatory proteins such as CDK8-CCNC, PIK3CA-PIK3R1, KYNU, and PRKCB.
Article
Biochemistry & Molecular Biology
Siyan Yu, Qunying Xie, Weifeng Tan, Manjiang Hu, Guiling Xu, Xiao Zhang, Guanghang Xie, Limei Mao
Summary: This study found that supplementation of fish oil with an appropriate higher ratio of DHA (1.5:1) can alleviate insulin resistance, reduce adipocyte hypertrophy and oxidative stress, improve lipid metabolism, and reduce hepatic steatosis in high-fat diet-induced insulin resistance mice.
Article
Oncology
S. G. Yammine, I. Huybrechts, C. Biessy, L. Dossus, S. Panico, M. J. Sanchez, V. Benetou, R. Turzanski-Fortner, V. Katzke, A. Idahl, G. Skeie, K. Standahl Olsen, A. Tjonneland, J. Halkjaer, S. Colorado-Yohar, A. K. Heath, E. Sonestedt, H. Sartor, M. B. Schulze, D. Palli, M. Crous-Bou, A. Dorronsoro, K. Overvad, A. Barricarte Gurrea, G. Severi, R. C. H. Vermeulen, T. M. Sandanger, R. C. Travis, T. Key, P. Amiano, B. Van Guelpen, M. Johansson, M. Sund, R. Tumino, N. Wareham, C. Sacerdote, V. Krogh, P. Brennan, E. Riboli, E. Weiderpass, M. J. Gunter, V. Chajes
Summary: Specific dietary fatty acids, such as gamma-linolenic acid and alpha-linolenic acid from plant sources, may be associated with lower risk of endometrial cancer.
Review
Multidisciplinary Sciences
Christos Markellos, Maria-Eleni Ourailidou, Maria Gavriatopoulou, Panagiotis Halvatsiotis, Theodoros N. Sergentanis, Theodora Psaltopoulou
Summary: This study found an association between olive oil consumption and a lower risk of cancer and better prognosis. Higher olive oil consumption was correlated with a decreased likelihood of developing any cancer, breast cancer, gastrointestinal cancer, upper aerodigestive cancer, and urinary tract cancer.
Article
Nutrition & Dietetics
Matteo Di Maso, Livia S. A. Augustin, Federica Toffolutti, Carmen Stocco, Luigino Dal Maso, David J. A. Jenkins, Neil E. Fleshner, Diego Serraino, Jerry Polesel
Summary: The study found that adherence to the Mediterranean diet and physical activity before diagnosis can have a beneficial impact on overall survival in prostate cancer patients, mainly driven by a reduction in non-prostate cancer mortality, which accounts for about 80% of deaths in men with prostate cancer.
Review
Biochemistry & Molecular Biology
Annemarie J. F. Westheim, Lara M. Stoffels, Ludwig J. Dubois, Jeroen van Bergenhenegouwen, Ardy van Helvoort, Ramon C. J. Langen, Ronit Shiri-Sverdlov, Jan Theys
Summary: Cancer burden is increasing rapidly globally, with lifestyle factors such as unhealthy diet being major contributors. The specific fatty acids that contribute to a healthy and balanced diet in terms of cancer risk and prognosis are still unclear. This review explores the associations between intake of different fatty acids and cancer risk, as well as the effects of specific fatty acids on tumor cells and inflammation-induced cancer progression, highlighting challenges and opportunities for fatty acid tailored nutritional interventions.
Article
Nutrition & Dietetics
Juan C. Pardo, Vicenc Ruiz de Porras, Joan Gil, Albert Font, Manel Puig-Domingo, Mireia Jorda
Summary: Prostate cancer is the most commonly diagnosed male malignancy in the Western world. Metabolic reprogramming and epigenetic remodeling play important roles in the progression and therapy resistance of prostate cancer, and there is crosstalk between metabolism and epigenetics. A high-fat diet has been associated with prostate cancer progression. Understanding these alterations and mechanisms can help identify prognostic and predictive biomarkers, as well as targetable vulnerabilities.
Article
Clinical Neurology
Jose Jimenez-Torres, Juan F. Alcala-Diaz, Jose D. Torres-Pena, Francisco M. Gutierrez-Mariscal, Ana Leon-Acuna, Purificacion Gomez-Luna, Carolina Fernandez-Gandara, Gracia M. Quintana-Navarro, Jose C. Fernandez-Garcia, Pablo Perez-Martinez, Jose M. Ordovas, Javier Delgado-Lista, Elena M. Yubero-Serrano, Jose Lopez-Miranda
Summary: The study compared the effects of a Mediterranean diet and a low-fat diet on cardiovascular disease prevention, finding that the Mediterranean diet could reduce the progression of atherosclerosis, as shown by decreased IMT-CC and carotid plaque height.
Article
Biochemistry & Molecular Biology
Hiromi Sato, Shintaro Narita, Masanori Ishida, Yoshiko Takahashi, Huang Mingguo, Soki Kashima, Ryohei Yamamoto, Atsushi Koizumi, Taketoshi Nara, Kazuyuki Numakura, Mitsuru Saito, Toshiaki Yoshioka, Tomonori Habuchi
Summary: A diet rich in lard increases the risk of prostate cancer development and progression. Two mouse models fed with lard-enriched diets showed enhanced prostate cancer progression and weight gain compared to a fish oil diet. The composition of gut microbiota differed significantly between the two diets, with changes in bacterial species such as Clostridiales and Lactobacillales. The proportion of Lactobacillales in the gut was negatively associated with weight gain and prostate cancer progression. The study also identified genes involved in lipid metabolism and cholesterol biosynthesis that correlated with the abundance of Lactobacillales in the gut.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nutrition & Dietetics
Monica Gianna Giroli, Jose Pablo Werba, Patrizia Rise, Benedetta Porro, Angelo Sala, Manuela Amato, Elena Tremoli, Alice Bonomi, Fabrizio Veglia
Summary: The study found that compared to a low-fat diet, the Mediterranean diet had a more favorable effect on blood fatty acid composition in patients with coronary heart disease on multiple therapies, particularly in terms of omega-3 levels.
Article
Oncology
Chi H. J. Kao, David R. Greenwood, Stephen M. F. Jamieson, Margaret E. Coe, Pamela M. Murray, Lynnette R. Ferguson, Karen S. Bishop
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2020)
Article
Nutrition & Dietetics
Nishi Karunasinghe, Lance Ng, Alice Wang, Venkatesh Vaidyanathan, Shuotun Zhu, Lynnette R. Ferguson
Review
Nutrition & Dietetics
Karen S. Bishop
Review
Orthopedics
Sharon Erdrich, Jason A. Hawrelak, Stephen P. Myers, Joanna E. Harnett
BMC MUSCULOSKELETAL DISORDERS
(2020)
Review
Food Science & Technology
Hartono Tanambell, Karen Suzanne Bishop, Siew Young Quek
Summary: Tangerine tomatoes may have superior health benefits compared to red tomatoes due to unique carotenoid composition, but further studies are needed to validate their potential health effects, especially on cardiovascular and bone health.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Multidisciplinary Sciences
Sharon Erdrich, Edwin C. K. Tan, Jason A. Hawrelak, Stephen P. Myers, Joanna E. Harnett
Summary: The study aimed to investigate the impact of pre-test mouthwash on hydrogen-methane breath test results, finding that mouthwash significantly reduced the concentration of expired hydrogen and/or methane gases in a majority of cases, potentially altering the diagnosis.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Alice Wang, Nishi Karunasinghe, Lindsay D. Plank, Shuotun Zhu, Sue Osborne, Charis Brown, Karen Bishop, Tiffany Schwass, Sofian Tijono, Michael Holmes, Jonathan Masters, Roger Huang, Christine Keven, Lynnette R. Ferguson, Ross Lawrenson
Summary: Androgen deprivation therapy in prostate cancer patients affects bone metabolism, with sclerostin, DKK-1, and OPG levels showing significant differences between ADT and non-ADT groups. Changes in DKK-1 and OPG levels were seen in longitudinal analysis, while correlations were found between sclerostin levels and BMD as well as testosterone levels.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Nishi Karunasinghe, Tsion Zewdu Minas, Bo-Ying Bao, Arier Lee, Alice Wang, Shuotun Zhu, Jonathan Masters, Megan Goudie, Shu-Pin Huang, Frank J. Jenkins, Lynnette R. Ferguson
Summary: This study analyzed multiple datasets and found significant associations between prostate-specific antigen (PSA) and demographic, lifestyle, and clinical data. The study also found variability in the correlation of PSA with age and genetic factors among different populations. The findings suggest that unique PSA cut-off thresholds, factored with demographics, lifestyle, and genetics, may be more appropriate for prostate cancer screening.
SCIENTIFIC REPORTS
(2022)
Review
Gastroenterology & Hepatology
Sharon Erdrich, Jason A. Hawrelak, Stephen P. Myers, Joanna E. Harnett
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
(2020)
Article
Integrative & Complementary Medicine
Sharon Erdrich, Jason A. Hawrelak, Stephen P. Myers, Joanna E. Harnett
ADVANCES IN INTEGRATIVE MEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Zhixia (Grace) Chen, Karen Suzanne Bishop, Hartono Tanambell, Peter Buchanan, Chris Smith, Siew Young Quek
Review
Health Care Sciences & Services
Toni Mitchell, Lewis Clarke, Alexandra Goldberg, Karen S. Bishop
Review
Health Care Sciences & Services
Amani Al Shaikh, Andrea J. Braakhuis, Karen S. Bishop
Article
Biochemistry & Molecular Biology
Hartono Tanambell, Siew Young Quek, Karen Suzanne Bishop
Article
Biochemistry & Molecular Biology
Zhixia (Grace) Chen, Karen Suzanne Bishop, Hartono Tanambell, Peter Buchanan, Siew Young Quek