Review
Psychiatry
Julija Gecaite-Stonciene, Christine Lochner, Clara Marincowitz, Naomi A. Fineberg, Dan J. Stein
Summary: ICD-11 has reformed the diagnosis of obsessive-compulsive personality disorder, focusing on its diagnostic validity and clinical utility. Research indicates an overlap between the ICD-11 anankastia domain and DSM-5 OCPD traits, with factor analyses supporting the diagnostic validity of this domain. Further studies are needed to fully explore the clinical utility of the ICD-11 PD model in relation to obsessive-compulsive and related disorders.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Leonardo F. Fontenelle, Lucy Albertella, Mary-Ellen Brierley, Emma M. Thompson, Louise Destree, Sam R. Chamberlain, Murat Yucel
Summary: This study investigated the deterioration of symptoms of obsessive-compulsive and related disorders (OCRDs) during the COVID-19 pandemic, finding that factors such as being female, experiencing more COVID-19 related stressful events, and having higher compulsivity traits predicted worsened symptoms during the pandemic. Identifying a pre-pandemic profile of individuals most at risk of symptom deterioration may be valuable for future preventative initiatives related to COVID-19 or other communicable diseases. Future studies should follow up on these findings longitudinally.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Psychiatry
Amanda R. Mahnke, Omer Linkovski, Kiara Timpano, Peter van Roessel, Catherine Sanchez, Andrea D. Varias, Pavithra Mukunda, Maria Filippou-Frye, Anthony Lombardi, Hannah Raila, Kelley Anderson, Thasveen Sandhu, Brianna Wright, Elizabeth A. McCarthy, Geronimo E. Garcia, Sepehr Asgari, Tori Qiu, Rebecca Bernert, Carolyn Rodriguez
Summary: Hoarding disorder (HD) is a mental disorder characterized by difficulty parting with possessions and impairing life functioning. Research shows that individuals with HD have poor sleep quality, higher levels of insomnia symptoms, and comorbid sleep disorders. Sleep may be a new target for treatment in improving outcomes for individuals with HD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Review
Psychiatry
Roger T. Mulder
Summary: The ICD-11 classification of personality disorders represents a paradigm shift in diagnosis, abolishing all previous categories except for a general description of personality disorder and allowing for specification of severity. It describes patient behavior using five personality trait domains and shows alignment with the DSM-5 Alternative Model for Personality Disorders. Early evidence on the reliability and validity of the new model is promising, but wider adoption by clinicians in regular clinical practice is needed for its success.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Karel D. Riegel, Albert J. Ksinan, Lucia Schlosserova
Summary: The study evaluated the validity and reliability of the 36-item PID5BF+M, confirming its good predictive validity for borderline psychopathology within the ICD-11 model. Further investigation is needed for the Disinhibition domain.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Karel D. D. Riegel, Lucia Schlosserova, Tadeas S. S. Zbornik
Summary: This study verifies the ability of the ICD-11 model to detect narcissistic pathology in addicted patients and confirms its differentiation capacity between clinical and non-clinical populations. The gender specificity related to gender and type of addiction and the associations between certain trait qualifiers and the overall degree of impairment in personality functioning are also confirmed.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Social
Johannes Stricker, Gordon L. Flett, Paul L. Hewitt, Reinhard Pietrowsky
Summary: The ICD-11 includes a dimensional model of personality disorder, while perfectionism traits are related but not redundant to this model, providing additional insights into explaining personality dysfunction.
PERSONALITY AND INDIVIDUAL DIFFERENCES
(2022)
Article
Psychiatry
Victor Blueml, Stephan Doering
Summary: The new ICD-11 introduces a fully dimensional classification of personality disorders, focusing on evaluating impairment in self and interpersonal functioning, which aligns with longstanding psychoanalytic/dynamic conceptualizations.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Matthias Brand, Marc N. Potenza
Summary: The Journal of Behavioral Addictions featured a debate on behavioral addictions in ICD-11 in 2022. The debate focused on compulsive sexual behavior disorder and emphasized the importance of further research on behavioral addictions. The debate was conducted at a high scientific level and has significant implications for behavioral addiction research and clinical practice.
JOURNAL OF BEHAVIORAL ADDICTIONS
(2023)
Review
Psychiatry
Olatunde O. Ayinde, Oye Gureje
Summary: Recent studies have shown support for the applicability of DSM-5 and ICD-11 in classifying personality disorders, with qualitative research exploring the perspectives of users and clinicians. The dimensional system of ICD-11 is slightly more useful than the categorical system of ICD-10. Further research is needed to confirm these observations.
CURRENT OPINION IN PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
Lee Anna Clark, Alejandro Corona-Espinosa, Shereen Khoo, Yuliya Kotelnikova, Holly F. Levin-Aspenson, Greg Serapio-Garcia, David Watson
Summary: The ICD-11 personality disorder model is the first comprehensive assessment tool for personality pathology, including PD dysfunction-severity and five trait qualifiers. Through exploratory factor analysis, it was found that the internal factor included self and interpersonal dysfunction, while the external factor included dissociality and reckless impulsivity.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychiatry
Azad Hemmati, Fateh Rahmani, Bo Bach
Summary: The study explored the structure of the ICD-11 and AMPD personality disorder trait domains in a large mixed sample from the Kurdistan zone of Iran. The findings suggest that the ICD-11 trait model may be more cross-culturally fitting than the DSM-5 AMPD trait model.
FRONTIERS IN PSYCHIATRY
(2021)
Editorial Material
Clinical Neurology
Trevor. W. Robbins
Summary: This scientific commentary discusses the research conducted by Kim et al. on the unbalanced fronto-pallidal neurocircuit underlying set shifting in patients with obsessive-compulsive disorder, published in the journal Brain.
Article
Psychiatry
Rute Pires, Joana Henriques-Calado, Ana Sousa Ferreira, Bo Bach, Marco Paulino, Joao Gama Marques, Ana Ribeiro Moreira, Jaime Gracio, Bruno Goncalves
Summary: The study examined the utility of ICD-11 and DSM-5 trait domains in differentiating patients with personality disorders from patients with other mental disorders. Results showed that individuals with personality disorders scored significantly higher in negative affectivity, antagonism/dissociality, disinhibition, emotional lability, manipulativeness, deceitfulness, and impulsivity. The trait domains of disinhibition, negative affectivity, and antagonism/dissociality, as well as the trait facets of impulsivity, deceitfulness, emotional lability, and manipulativeness, were identified as key discriminators between PD and non-PD patients. The PID5BF+M composite score was also highlighted as a reliable global severity index for detecting personality dysfunction.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
Clara Law, Snigdha Kamarsu, Immanuela C. Obisie-Orlu, Gina M. Belli, Maria Mancebo, Jane Eisen, Steven Rasmussen, Christina L. Boisseau
Summary: Personality traits may impact the course and symptom presentation of OCD, with low extraversion being associated with a decreased rate of remission. Other personality traits were not associated with remission.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Clinical
Matti Cervin, Euripedes C. Miguel, Aysegul Selcen Guler, Ygor A. Ferrao, Ayse Burcu Erdogdu, Luisa Lazaro, Sebla Gokce, Daniel A. Geller, Yasemin Yulaf, Saziye Senem Basgul, Ozlem Ozcan, Koray Karabekiroglu, Leonardo F. Fontenelle, Yanki Yazgan, Eric A. Storch, James F. Leckman, Maria Conceicao do Rosario, David Mataix-Cols
Summary: This study established a comprehensive symptom structure model of OCD across the lifespan, consisting of eight broad dimensions valid across the lifespan. Incompleteness and Disturbing Thoughts were found to be most central in the network analysis, with unique interconnections to other dimensions. The eight broad dimensions were differentially related to sociodemographic and clinical variables.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Clinical Neurology
Donatella Marazziti, Filippo M. Barberi, Leonardo Fontenelle, Beatrice Buccianelli, Manuel G. Carbone, Elisabetta Parra, Stefania Palermo, Lucia Massa, Claudia Tagliarini, Alessandra Della Vecchia, Federico Mucci, Alessandro Arone, Liliana Dell'Osso
Summary: This study compared vitamin D levels in adult patients with obsessive-compulsive disorder (OCD) and explored possible correlations with patients' characteristics. The results showed a negative correlation between vitamin D levels and the severity of OCD and specific symptoms, with some differences based on gender. Further research is needed to confirm these findings and evaluate the effectiveness of vitamin D supplementation in OCD patients.
Article
Clinical Neurology
Mary-Ellen E. Brierley, Lucy Albertella, Kristian Rotaru, Louise Destree, Emma M. Thompson, Chang Liu, Erynn Christensen, Amelia Lowe, Rebecca A. Segrave, Karyn E. Richardson, Edouard Kayayan, Samuel R. Chamberlain, Jon E. Grant, Rico S. C. Lee, Sam Hughes, Murat Yucel, Leonardo F. Fontenelle
Summary: This study investigates the relationships between compulsivity and diet quality, sleep quality, and physical activity, and finds that psychological distress mediates these relationships. Lifestyle interventions for compulsivity should focus on reducing psychological distress, followed by improving sleep and diet quality.
Article
Psychiatry
Zoe Bettess, Lucy Albertella, Louise Destree, Maria C. Rosario, Ygor Arzeno Ferrao, Euripedes C. Miguel, Leonardo F. Fontenelle
Summary: This study found that transformation obsessions (TO) may be better conceptualized as forbidden/taboo thoughts rather than contamination. Patients with TO displayed increased suicidality, overall younger age, and a significantly larger disparity between seeking treatment and OCD diagnosis.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Article
Psychiatry
Mary-Ellen E. Brierley, Lucy Albertella, Erynn Christensen, Kristian Rotaru, Felice N. Jacka, Rebecca A. Segrave, Karyn E. Richardson, Rico S. C. Lee, Edouard Kayayan, Sam Hughes, Murat Yucel, Leonardo F. Fontenelle
Summary: This study examined the impact of lifestyle factors on obsessive-compulsive symptoms and problematic repetitive behaviors. The results showed that lower intake of vegetables and oily fish, as well as lower moderate intensity physical activity, predicted higher obsessive-compulsive symptoms. Higher intake of high-fat foods predicted higher compulsive problematic repetitive behaviors. The study suggests the potential importance of lifestyle interventions for individuals experiencing compulsivity-related behaviors and/or symptoms.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Review
Clinical Neurology
Barbara P. Stumpf, Leonardo C. de Souza, Marina S. F. Mourao, Fabio L. Rocha, Leonardo F. Fontenelle, Izabela G. Barbosa
Summary: This study aimed to review the cognitive performance of patients with hoarding disorder (HD) compared to controls. The results showed that HD patients only showed impairment in categorization skills, while their cognitive performance in other domains did not differ significantly from controls. There is a lack of research on social cognition and the impact of emotions on cognitive performance in HD patients, calling for further investigation.
Article
Environmental Sciences
Chang Liu, Kristian Rotaru, Samuel R. Chamberlain, Lei Ren, Leonardo F. Fontenelle, Rico S. C. Lee, Chao Suo, Kavya Raj, Murat Yucel, Lucy Albertella
Summary: This study examined whether distress-driven impulsivity and psychological flexibility interactively contribute to problematic internet use. The findings suggest that psychological inflexibility moderates the association between distress-driven impulsivity and problematic internet use.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Psychiatry
Matti Cervin, Maria Conceicao do Rosario, Leonardo F. Fontenelle, Ygor A. Ferrao, Marcelo C. Batistuzzo, Albina R. Torres, Rodolfo F. Damiano, Lorena Fernandez de la Cruz, Euripedes C. Miguel, David Mataix-Cols
Summary: Individuals with OCD have a higher risk of thinking about, attempting, and dying by suicide compared to the general population. Taboo obsessions, the general OCD factor, lifetime major depression, and lifetime substance use disorders significantly predict suicidality in patients with OCD. Taboo obsessions may explain a small proportion of the variance in suicidality and should be considered an independent risk factor.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychiatry
Erin Crowe, Maria C. Rosario, Ygor A. Ferrao, Lucy Albertella, Euripedes C. Miguel, Leonardo F. Fontenelle
Summary: The study aimed to investigate the demographics, comorbid disorders, and obsessive-compulsive symptoms associated with Obsessional Slowness (OS). The cross-sectional data from 667 OCD outpatients were analyzed, revealing that being single, having tics, and displaying higher severity of specific OCD symptoms predicted the presence of OS.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE
(2023)
Article
Clinical Neurology
Louise Destree, Lucy Albertella, Laura Jobson, Patrick McGorry, Andrew Chanen, Aswin Ratheesh, Christopher Davey, Andrea Polari, Paul Amminger, Hok Pan Yuen, Jessica Hartmann, Rachael Spooner, Leonardo F. Fontenelle, Barnaby Nelson
Summary: This study investigated the association between stressful experiences and obsessive-compulsive symptoms. The results showed that stressful experiences were associated with the symmetry dimension of obsessive-compulsive symptoms. Borderline personality disorder symptoms were positively associated with the symmetry and fear of harm dimensions, while psychosis symptoms were negatively associated with the fear of harm dimension.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Biochemistry & Molecular Biology
Shinsuke Suzuki, Xiaoliu Zhang, Amir Dezfouli, Leah Braganza, Ben D. Fulcher, Linden Parkes, Leonardo F. Fontenelle, Ben J. Harrison, Carsten Murawski, Murat Yucel, Chao Suo
Summary: Obsessive-compulsive disorder (OCD) and pathological gambling (PG) are associated with deficits in behavioural flexibility. Model-based functional magnetic resonance imaging (fMRI) reveals altered reward-learning in OCD and PG, with OCD patients showing lower learning rates for worse-than-expected outcomes and attenuated encoding of negative reward prediction errors, and PG patients showing higher and lower learning rates for better- and worse-than-expected outcomes, respectively, accompanied with higher encoding of positive reward prediction errors. Perseveration did not significantly differ between the patient groups and healthy controls.
Article
Health Care Sciences & Services
Rico S. C. Lee, Lucy Albertella, Erynn Christensen, Chao Suo, Rebecca A. Segrave, Maja Brydevall, Rebecca Kirkham, Chang Liu, Leonardo F. Fontenelle, Samuel R. Chamberlain, Kristian Rotaru, Murat Yucel
Summary: The purpose of this study was to validate a gamified battery of neurocognitive tasks for assessing addictive behaviors. The findings showed that the gamified tasks were sufficiently valid for assessing key neurocognitive processes related to addiction. This validation has significant implications for risk detection and the successful deployment of next-generation assessment tools for substance use or misuse and other mental disorders characterized by neurocognitive anomalies.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Multidisciplinary Sciences
Campbell Ince, Leonardo F. Fontenelle, Adrian Carter, Lucy Albertella, Jeggan Tiego, Samuel R. Chamberlain, Kristian Rotaru
Summary: Problematic pornography use is a complex and growing research area, but limited knowledge exists regarding the lived experience of individuals with this issue. An online qualitative study revealed dimensions that have not been fully explored, including various mental and physical complaints, sexual functioning deficits with real partners, and subjective changes in sexual arousal while using pornography. The study also expanded on understanding the inner conflict associated with problematic pornography use and clarified ways in which users can progress to more intensified patterns of use.
SCIENTIFIC REPORTS
(2023)
Article
Psychiatry
Marcelo Piquet-Pessoa, Joane de Oliveira, Ana Paula Ribeiro, Lucy Albertella, Gabriela M. Ferreira, Gabriela B. de Menezes, Leonardo F. Fontenelle
Summary: This study investigated whether the habitual use of alcohol in patients with alcohol use disorder (AUD) at baseline would lead to worse outcomes after one year of follow-up. The results showed that greater fear and reward motivations for alcohol use predicted a greater improvement in AUD symptoms at the end of one year. These findings may contribute to the development of new approaches for AUD treatment and inform addiction research models.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Clinical Neurology
Beatrice Benatti, Giulia Lucca, Riccardo Zanello, Fabio Fesce, Alberto Priori, Nicola Poloni, Camilla Callegari, Leonardo F. Fontenelle, Bernardo Dell'Osso
Summary: This study is the first to apply a staging model to OCD patients and found that staging changed during the follow-up period. The study found that patients with worsened stage had poorer comorbidity rates and employment characteristics, while patients with improved stage had higher rates of magical thinking and violence/harm obsessions.