The molecular and pathophysiological implications of hepatitis B X antigen in chronic hepatitis B virus infection

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

(2011) Julie Lucifora et al.   JOURNAL OF HEPATOLOGY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the sleeping beauty transposon system

(2010) Vincent W. Keng et al.   HEPATOLOGY

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice

(2010) M. Tsuge et al.   JOURNAL OF GENERAL VIROLOGY

The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein

(2010) C. Wei et al.   JOURNAL OF IMMUNOLOGY

The Hepatitis B Virus X Protein Modulates Hepatocyte Proliferation Pathways To Stimulate Viral Replication

(2010) T. L. Gearhart et al.   JOURNAL OF VIROLOGY

HBx-induced reactive oxygen species activates hepatocellular carcinogenesisviadysregulation of PTEN/Akt pathway

(2010) Hye-Lin Ha   WORLD JOURNAL OF GASTROENTEROLOGY

Putative roles of hepatitis B x antigen in the pathogenesis of chronic liver disease

(2009) Mark A. Feitelson et al.   CANCER LETTERS

Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)-associated liver diseases: Evidence for an HBV X protein-mediated inhibition of PTTG1 ubiquitination and degradation

(2009) Francisca Molina-Jiménez et al.   HEPATOLOGY

Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expression

(2009) M.-Y. Cha et al.   JOURNAL OF GENERAL VIROLOGY

Role of the HBx oncoprotein in carbonic anhydrase 9 induction

(2009) Tereza Holotnakova et al.   JOURNAL OF MEDICAL VIROLOGY

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function

(2009) L. Belloni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice

(2009) Victor V. Keasler et al.   VIROLOGY

Premature Cell Cycle Entry Induced by Hepatitis B Virus Regulatory HBx Protein during Compensatory Liver Regeneration

(2008) A. J. Hodgson et al.   CANCER RESEARCH

COOH-Terminal Truncated HBV X Protein Plays Key Role in Hepatocarcinogenesis

(2008) N.-F. Ma et al.   CLINICAL CANCER RESEARCH

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1

(2008) Silvia Martin-Lluesma et al.   HEPATOLOGY

The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells

(2008) Samuel Martín-Vílchez et al.   HEPATOLOGY

Hepatitis B Virus X Protein Increases the Cdt1-to-Geminin Ratio Inducing DNA Re-replication and Polyploidy

(2008) Lova Rakotomalala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis B Virus X Protein via the p38MAPK Pathway Induces E2F1 Release and ATR Kinase Activation Mediating p53 Apoptosis

(2008) Wen-Horng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis B Virus HBx Protein Localizes to Mitochondria in Primary Rat Hepatocytes and Modulates Mitochondrial Membrane Potential

(2008) A. J. Clippinger et al.   JOURNAL OF VIROLOGY

Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells

(2008) Y-G Yoo et al.   ONCOGENE

HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint

(2008) S Kim et al.   ONCOGENE

Mouse models in liver cancer research: A review of current literature

(2008) Martijn WH Leenders et al.   WORLD JOURNAL OF GASTROENTEROLOGY