Review
Endocrinology & Metabolism
Ajit S. Divakaruni, Martin Jastroch
Summary: Measurement of oxygen consumption is an important experimental technique that can provide valuable insights into mitochondrial function and its impact on cell physiology. This guide offers practical recommendations for experimental design, data collection, and interpretation to enhance the reproducibility and reliability of oxygen consumption measurements.
Review
Chemistry, Multidisciplinary
Nick A. Shepelin, Zahra P. Tehrani, Natacha Ohannessian, Christof W. Schneider, Daniele Pergolesi, Thomas Lippert
Summary: Nanoscale thin films have a wide range of applications in various fields, and their functional tunability based on chemical composition has driven human progress. Pulsed laser deposition is an important method for fabricating thin films, using laser energy to form a plasma and deposit material onto a substrate. This technique allows for the production of crystalline films with a wide range of atmospheric conditions and chemical complexity. However, achieving high quality films with desired composition requires rigorous optimization of growth parameters. This tutorial review provides an overview of pulsed laser deposition, discusses the effects of growth parameters on film properties, and explores in situ monitoring techniques.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Engineering, Biomedical
Gemma Mestres, Sarah-Sophia D. Carter, Nils P. Hailer, Anna Diez-Escudero
Summary: Biomaterials offer a promising approach to repair bone defects, with a focus on osteoimmunology to modulate the immune response and to support bone regeneration. Various in vitro assays are used to evaluate the OIM properties of biomaterials, but selecting the right methods can be challenging. This review aims to provide a comprehensive guide for researchers interested in studying the OIM properties of biomaterials in vitro.
ACTA BIOMATERIALIA
(2021)
Article
Chemistry, Analytical
Hui-Yin Chang, Sean M. Colby, Xiuxia Du, Javier D. Gomez, Maximilian J. Helf, Katerina Kechris, Christine R. Kirkpatrick, Shuzhao Li, Gary J. Patti, Ryan S. Renslow, Shankar Subramaniam, Mukesh Verma, Jianguo Xia, Jamey D. Young
Summary: This article introduces important considerations for metabolomics software users and developers, and provides recommendations for establishing guidelines and best practices for developing metabolomics tools, divided into three stages: preparation, tool development, and distribution and maintenance.
ANALYTICAL CHEMISTRY
(2021)
Review
Immunology
James W. Reinhardt, Christopher K. Breuer
Summary: This review details past studies on fibrocytes, their findings, and discusses their strengths and limitations, aiming to identify opportunities for further investigation and promote best practices in future study design.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Biochemical Research Methods
Brian J. Bender, Stefan Gahbauer, Andreas Luttens, Jiankun Lyu, Chase M. Webb, Reed M. Stein, Elissa A. Fink, Trent E. Balius, Jens Carlsson, John J. Irwin, Brian K. Shoichet
Summary: Structure-based docking screens of compound libraries are common in early drug and probe discovery. Best practices and control calculations are outlined to evaluate docking parameters prior to undertaking a large-scale prospective screen.
Article
Quantum Science & Technology
Yvonne Y. Gao, M. Adriaan Rol, Steven Touzard, Chen Wang
Summary: Quantum computing offers a powerful new paradigm of information processing with the potential to transform various industries. Rapid progress has been made in circuit quantum electrodynamics technology, emerging as one of the most promising physical systems for achieving full-stack quantum computing.
Article
Environmental Sciences
Rebecca Myszka, Marie Enfrin, Filippo Giustozzi
Summary: The contamination of road dust by microplastics is a serious concern due to its ecological and health implications. Current technologies for detecting microplastics in road dust have limitations, and there is a need for more accurate and efficient techniques, especially with the increasing use of recycled plastic in road infrastructure. This study investigates the use of Nile red staining to detect microplastics in road dust and provides information about their characteristics.
Article
Biochemistry & Molecular Biology
Alexander A. Gooden, Christine N. Evans, Timothy P. Sheets, Michelle E. Clapp, Raj Chari
Summary: With the advancement of technology, CRISPR has been widely used in various organisms and experimental settings. dbGuide is a database providing functionally validated guide RNA sequences for CRISPR/Cas9 gene editing, containing over 4000 validated sequences.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Biochemical Research Methods
Maxime Tarabichi, Adriana Salcedo, Amit G. Deshwar, Maire Ni Leathlobhair, Jeff Wintersinger, David C. Wedge, Peter Van Loo, Quaid D. Morris, Paul C. Boutros
Summary: The Perspective reviews computational methods for subclonal reconstruction in cancer evolution studies, outlining complex approaches and best practices for analysis. It provides insight into clonality and mutational processes, identifying underlying assumptions and uncertainties in each step. This guide serves as a pragmatic resource for the growing user community of subclonal reconstruction methods.
Review
Nutrition & Dietetics
Leontien Depoorter, Yvan Vandenplas
Summary: The administration of probiotics in children has been studied extensively worldwide, showing significant benefits. However, due to study heterogeneity and risk of bias, there is currently no broad consensus on specific probiotic strains, doses, and treatment regimens for certain pediatric indications.
Article
Critical Care Medicine
Heatherlee Bailey, Lewis J. Kaplan
Summary: Volunteerism for humanitarian aid is a response to disasters, crises, and conflict. Healthcare volunteers face personal risks and their decision-making is influenced by personal, structural, and crisis-specific factors. Practical approaches to travel and on-scene safety should be considered to benefit volunteers, including planning for evacuation and potential rescue. The medical community should improve medical education and professional development to support humanitarian aid volunteerism.
Article
Biochemical Research Methods
Viet-Khoa Tran-Nguyen, Muhammad Junaid, Saw Simeon, Pedro J. Ballester
Summary: Structure-based virtual screening (SBVS) via docking has been effectively used to discover active molecules for therapeutic targets. Artificial intelligence, particularly machine learning, has been utilized to build scoring functions (SFs) for SBVS. This article presents a comprehensive protocol for building and evaluating these SFs to enhance SBVS performance.
Review
Genetics & Heredity
Xiulan Chen, Yaping Sun, Tingting Zhang, Lian Shu, Peter Roepstorff, Fuquan Yang
Summary: Isobaric labeling technology has become a key tool for comparing protein expression in biological samples, although challenges remain in terms of quantitative accuracy and precision. The different types of isobaric mass tags and advantages and disadvantages of the labeling method are detailed, along with precautions needed at each step of the workflow for reliable quantification results. The broad applications of isobaric labeling technology in biological and clinical studies, with a focus on thermal proteome profiling and proteogenomics, are also discussed.
GENOMICS PROTEOMICS & BIOINFORMATICS
(2021)
Review
Clinical Neurology
Arianna Manini, Leonardo Pantoni
Summary: Cerebral small vessel disease (CSVD) refers to various diseases that affect the brain as well as small arteries, arterioles, venules, and capillaries. The causes of CSVD are complex, with some of them being genetic. Monogenic CSVDs account for 1%-5% of all strokes and have associations with other disorders. Neurologists should have adequate knowledge of the genetic background of CSVD to select appropriate patients for genetic assessment and determine which genes to analyze. This review aims to summarize the clinical, neurologic and non-neurologic, and neuroimaging features of monogenic CSVD and provide a flowchart for clinical practice.
Article
Energy & Fuels
Jierui Li, Weidong Liu, Sunan Cong, Yalong Li, Kai Zheng, Xun Luo, Wenbo Luo, Xiangdong Su
Summary: The study screened a stable water-in-oil emulsion suitable for surfactant-polymer flooding through ultrasonic emulsification experiments, and investigated its transport characteristics in conglomerate cores. It was found that when the emulsion flows in heterogeneous parallel conglomerate cores, it has conformance control.
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING
(2022)
Article
Behavioral Sciences
Maorui Kou, Huoyin Zhang, Yanzhen Lv, Wenbo Luo
Summary: This study used event-related potential (ERP) to explore the neural mechanisms of self-evaluation in individuals with a depression tendency during social comparison. The results showed that both depression tendency and stranger result influenced self-evaluation, and the subjective reports of the participants were found to have a certain degree of concealment.
Article
Chemistry, Physical
Wenbo Luo, Yunzhe Feng, Zhiyong Xue, Qinke Kong, Xiuzhu Han
Summary: Mg-(Al-)Ti laminated sheets with large bonding interfaces were prepared using a differential temperature hot-rolling process, resulting in higher strength and elastic modulus compared to rolled AZ31B sheets. The interfaces exhibited higher hardness and solid-solution regions of Mg(Al) and Ti(Al), with no intermetallic compounds generated during the rolling process and annealing treatment.
Article
Polymer Science
Yan Li, Wenbo Luo, Maodong Li, Bo Yang, Xiu Liu
Summary: Directly using laboratory loading rates to evaluate the long-term creep strength of polymers is not conservative. A suitable strain rate-dependent constitutive model is crucial for accurately predicting the long-term strength and mechanical behavior of polymer pressure pipes. In this study, the Kondner hyperbolic constitutive model is considered as the base model, and the yield stress and initial tangent modulus are the two rate-dependent parameters. Uniaxial tension tests are carried out to obtain these two parameters, and it is found that the power-law rate-dependent Kondner model is more suitable for describing the rate-dependent tensile behavior of PE100 pipe material.
Article
Neurosciences
Yiwen Li, Mingming Zhang, Shuaicheng Liu, Wenbo Luo
Summary: This study investigated the temporal dynamics of different dimensional face information (such as age, gender, emotion, and identity) in neural responses. The results revealed that facial emotion was processed before facial identity and lasted for a long time.
Article
Materials Science, Multidisciplinary
Dailei Zhu, Wenbo Luo, Kaibiao Wang, Jintao Xu, Shitian Huang, Yao Shuai, Chuangui Wu, Wanli Zhang
Summary: 4H-silicon carbide on silicon (4H-SiC on Si) has been transferred onto silicon substrate using crystal-ion-slicing (CIS) technology. Plasma activation is used to enhance bonding strength, resulting in improved film quality and interface compactness.
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
(2023)
Article
Computer Science, Theory & Methods
Li-Wei Chen, Ziang Chen, Werner Schindler, Xianyue Zhao, Heidemarie Schmidt, Nan Du, Ilia Polian
Summary: Memristive technologies offer fascinating opportunities for unconventional computing architectures and emerging applications. However, the security vulnerabilities of memristive technologies for implementing cryptographic circuits have been largely neglected. This article provides the first in-depth analysis of power side-channel analysis against memristive cryptographic implementations, and proposes a power estimation model and effective attack countermeasures.
IEEE TRANSACTIONS ON INFORMATION FORENSICS AND SECURITY
(2023)
Article
Nanoscience & Nanotechnology
Jiejun Wang, Xinqiang Pan, Wenbo Luo, Yao Shuai, Qin Xie, Jiaqi Xu, Zeqian Song, Chuangui Wu, Wanli Zhang
Summary: By fabricating memristors based on Ar+-irradiated SC-LNO thin film, this study successfully mimics various phenomena and memory mechanisms of biological synapses, and proposes an experience-based image processing approach using multi-pattern memorization.
ADVANCED ELECTRONIC MATERIALS
(2023)
Review
Psychiatry
Zhiyan Wang, Chengqian Hou, Lei Chen, Mingming Zhang, Wenbo Luo
Summary: Studies have shown that gut microbiota may affect different stages of drug use disorders, including inducing the search for new substances, involvement in drug metabolism, symptom correlation, and influencing drug relapse.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Experimental
Xuhua Hu, Bengang Feng, Lihong Chen, Wenbo Luo
Summary: Threat, in the form of threatening animal images, significantly decreases the magnitude of the Ebbinghaus illusion in the low-spatial-frequency range. Fearful face images have a comparable effect to neutral face images on the illusion magnitude in both spatial frequency ranges. The inhibition of left temporo-parietal junction reduces the effect of fearful face images on the illusion magnitude in the low-spatial-frequency range, while right TPJ stimulation produces the opposite pattern of results.
Article
Psychology, Multidisciplinary
Mingming Zhang, Ping Li, Lu Yu, Jie Ren, Shuxin Jia, Chaolun Wang, Weiqi He, Wenbo Luo
Summary: In daily life, individuals need to recognize and update emotional information from others' changing body expressions. This study found that emotional bodies can enhance working memory performance, highlighting the importance of emotional action information in working memory.
Article
Construction & Building Technology
Zhichao Wang, Donghai Liu, Bin Hu, Chongzheng Zhu, Wenbo Luo
Summary: The research on the fatigue performance of recycled asphalt mixture and the establishment of its fatigue life prediction model is crucial for its large-scale engineering application. Through fatigue tests, this study investigated the influencing factors and developed a new fatigue prediction model for recycled asphalt pavement. The results showed that the model accurately predicts the fatigue life of recycled asphalt mixtures with different RAP contents.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Xianyue Zhao, Stephan Menzel, Ilia Polian, Heidemarie Schmidt, Nan Du
Summary: This review comprehensively examines the state-of-the-art research on resistive switching (RS) in BiFeO3 (BFO)-based memristive devices. It discusses the fabrication techniques for preparing functional BFO layers, analyzes the lattice systems and crystal types responsible for RS behaviors, and reviews the underlying physical mechanisms and effects influencing RS in BFO-based memristive devices. Furthermore, the review explores the applications of BFO devices, evaluates energy consumption in RS, and discusses potential optimization techniques for memristive devices.
Article
Mathematical & Computational Biology
Chunliang Feng, Frank Krueger, Ruolei Gu, Wenbo Luo
Summary: The study used machine learning to explore biomarkers associated with fear of negative evaluation in the human brain. The results revealed several brain regions with predictive power for this fear, including those involved in negative emotional experience, regulation of emotional feeling, and encoding and retrieval of emotional memory.
QUANTITATIVE BIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Boyuan Yin, Haibo Wen, Wenbo Luo
Summary: This paper investigates the effects of thermo-oxidative aging on carbon-black filled rubber vulcanizates. The results show that the storage modulus and loss modulus increase with aging time, and the hysteresis loss of the material also increases with dynamic strain amplitude, aging time, and aging temperature.
NPJ MATERIALS DEGRADATION
(2022)