Review
Biochemical Research Methods
Ling Ma, Baowei Fei
Summary: Surgical microscopes are increasingly used in operating rooms for providing adjustable magnification, bright illumination, and clear visualization of the surgical field. Advanced surgical microscopes are integrated with various imaging modalities, such as optical coherence tomography (OCT), fluorescence imaging, and augmented reality (AR) for image-guided surgery, enhancing clinical practices and improving surgical outcomes.
JOURNAL OF BIOMEDICAL OPTICS
(2021)
Article
Multidisciplinary Sciences
Weihan Hou, Yangjie Wei
Summary: An improved method for calculating the intensity transmission and distribution of conventional optical microscopes was proposed, along with a simplified mathematical relationship between the blur degree and camera parameters. The method was validated through simulations and experiments.
Article
Biochemical Research Methods
Joseph R. R. Scherrer, Galen F. F. Lynch, Jie J. J. Zhang, Michale S. S. Fee
Summary: We present a fluorescence microscope light path that allows imaging of thousands of neurons in mice and hundreds of neurons in juvenile songbirds during free behavior. The light path eliminates traditional illumination optics, resulting in head-mounted microscopes that are lighter and have a larger field of view (FOV). Two microscopes were designed using this light path: one optimized for FOV (approximately 4 mm FOV; 1.4 g), and the other optimized for weight (1.0 mm FOV; 1.0 g).
Article
Biochemical Research Methods
Jitao Zhang, Giuliano Scarcelli
Summary: Brillouin optical spectroscopy has long been known as a noncontact material characterization modality. Recently, confocal Brillouin microscopy has emerged as a unique complementary tool, allowing noncontact, nonperturbative, label-free measurements of material mechanical properties.
Review
Multidisciplinary Sciences
Weihan Hou, Yangjie Wei
Summary: This study provides a comprehensive analysis and comparison of various methods for acquiring the point spread function (PSF) in conventional optical microscopy, and proposes two new methods with demonstrated effectiveness. It is of great significance for evaluating and enhancing the imaging resolution of microscopy.
Article
Chemistry, Multidisciplinary
Johtaro Yamamoto, Akira Sasaki
Summary: The study developed a fiber-optic-based fluorescence correlation spectroscopy system that can measure the diffusion dynamics and concentration of fluorescent molecules without the need for mechanical adjustment of the experimental setup. This system was successfully applied to measure the hydrodynamic diameters and concentrations of organic fluorescent dyes and fluorescently labeled proteins.
APPLIED SCIENCES-BASEL
(2021)
Article
Oncology
David Reichert, Lisa I. Wadiura, Mikael T. Erkkilae, Johanna Gesperger, Alexandra Lang, Thomas Roetzer-Pejrimovsky, Jessica Makolli, Adelheid Woehrer, Marco Wilzbach, Christoph Hauger, Barbara Kiesel, Marco Andreana, Angelika Unterhuber, Wolfgang Drexler, Georg Widhalm, Rainer A. Leitgeb
Summary: Optical imaging of autofluorescence is a powerful tool for monitoring metabolic changes and transformation in brain tumors. The increase in protein-bound FMN fluorescence in brain tumors indicates a shift toward a more glycolytic metabolism. These metrics show promise for machine learning based brain tumor classification.
FRONTIERS IN ONCOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Wenxin Lu, Lei Gong, Chaorui Su, Qibao Wang, Qing Ling, Peng Wang, Dongdong Qi, Yongzhong Bian
Summary: A new pair of porphyrin dimers were synthesized and studied for their supramolecular interactions with chiral diamines. The results showed sensitive circular dichroism responses, with CD signs determined by the stereostructure of the chiral diamine guests.
FRONTIERS IN CHEMISTRY
(2021)
Article
Optics
Dmitry N. Artemyev, Anastasia A. Shatskaya
Summary: In this study, we investigated the spurious signal effects in a typical fiber-optic setup used for Raman scattering registration. By analyzing the data obtained for each system component, we found that the mode of the laser with a volume Bragg grating is one of the major causes of the spurious signals.
OPTICS AND LASER TECHNOLOGY
(2022)
Article
Optics
Jonas Zahringer, Fiona Cole, Johann Bohlen, Florian Steiner, Izabela Kaminska, Philip Tinnefeld
Summary: 3D super-resolution microscopy with nanometric resolution is achieved by combining pMINFLUX for 2D localization, GET for axial information, and DNA-PAINT for single-molecule switching. The precision of localization is < 2 nm in all 3 dimensions, with axial precision below 0.3 nm. Structural features, such as individual docking strands at distances of 3 nm, are directly resolved using 3D DNA-PAINT measurements. The combination of pMINFLUX and GET provides synergetic effects for super-resolution imaging near surfaces, while L-PAINT improves signal-to-background ratio and imaging speed for local clusters.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Chemistry, Physical
Vivek Tiwari
Summary: Coherent multidimensional spectroscopies have been implemented across different regions of the electromagnetic spectrum over the past two decades, providing new insights into molecular scale phenomena. Recent technological developments have enabled higher spatial resolution while addressing issues caused by ensemble averaging.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Editorial Material
Multidisciplinary Sciences
Jyoti Madhusoodanan
Summary: Automated microscopes that adjust to the unique characteristics of each sample can accurately capture elusive biological phenomena with high level of detail.
Article
Biochemical Research Methods
Iris Schmidt, Wouter B. Nagengast, Dominic J. Robinson
Summary: The study investigated factors influencing device calibration and tissue optical property determination, validating findings through phantom and clinical studies. Results showed that the quality of intralipid phantom and fiber tree performance were the main factors affecting calibration quality.
JOURNAL OF BIOMEDICAL OPTICS
(2022)
Article
Materials Science, Multidisciplinary
Chuan-Lei Jia, Wei-Jia Tang, Ke Liu, Yang Liao
Summary: We present the fabrication and characterization of dual-line waveguides in Ho,Yb:YAG crystal using femtosecond laser writing. Efficient single-mode guidance is achieved in the type II waveguide structures at 632.8 nm. The lattice-damaged tracks and strain-affected regions are characterized using confocal micro-Raman spectroscopy. The preservation of fluorescence from Ho3+ and Yb3+ ions in the Ho,Yb:YAG waveguide is demonstrated through micro-luminescence studies.
Article
Physics, Multidisciplinary
Mengyan Zeng, Yao Huang, Baolin Zhang, Zixiao Ma, Yanmei Hao, Ruming Hu, Huaqing Zhang, Hua Guan, Kelin Gao
Summary: A liquid-nitrogen cryogenic Ca-40(+) optical clock is presented to reduce the blackbody radiation (BBR) shift. Various improvements have been made to increase its performance, including increasing the liquid-nitrogen maintenance time, decreasing the trap position recovery time, and reducing the magnetic field noise felt by the ions.
Article
Physics, Multidisciplinary
Katsuya Shimizu
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN
(2020)
Article
Multidisciplinary Sciences
Hiroki Kato, Hideo Nagatomo, Mitsuo Nakai, Tatsuhiro Sakaiya, Hidenori Terasaki, Tadashi Kondo, Yoichiro Hironaka, Katsuya Shimizu, Keisuke Shigemori
SCIENTIFIC REPORTS
(2020)
Article
Physics, Applied
Masafumi Sakata, Mari Einaga, Meng Dezhong, Toyoto Sato, Shin-ichi Orimo, Katsuya Shimizu
SUPERCONDUCTOR SCIENCE & TECHNOLOGY
(2020)
Article
Physics, Applied
Ryo Matsumoto, Mari Einaga, Shintaro Adachi, Sayaka Yamamoto, Tetsuo Irifune, Kensei Terashima, Hiroyuki Takeya, Yuki Nakamoto, Katsuya Shimizu, Yoshihiko Takano
SUPERCONDUCTOR SCIENCE & TECHNOLOGY
(2020)
Article
Chemistry, Physical
Keiji Kuno, Takahiro Matsuoka, Ryo Masuda, Takaya Mitsui, Makoto Seto, Akihiko Machida, Hiroshi Fujihisa, Naohisa Hirao, Yasuo Ohishi, Katsuya Shimizu, Shigeo Sasaki
Summary: Raman scattering, Mossbauer spectroscopy, and X-ray diffraction measurements have revealed crystal structure changes and Eu2+ to Eu3+ transformations in EuHx compressed in high-pressure H-2, through multiple mixed-valence phase transitions. A transition occurs near 7.0 GPa, and Mossbauer spectroscopy can serve as a useful marker for detecting hydrogen storage in metal hydrides.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Materials Science, Multidisciplinary
Takahiro Matsuoka, Hiroshi Fujihisa, Takahiro Ishikawa, Takaya Nakagawa, Keiji Kuno, Naohisa Hirao, Yasuo Ohishi, Katsuya Shimizu, Shigeo Sasaki
PHYSICAL REVIEW MATERIALS
(2020)
Article
Physics, Multidisciplinary
Takahiro Matsuoka, Amanda Haglund, Rui Xue, Jesse S. Smith, Maik Lang, Antonio M. dos Santos, David Mandrus
Summary: The study found that the pressure-induced insulator to metal transition in layered magnetic nickel phosphorous tri-sulfide NiPS3 occurs at 35 GPa, with no evidence of superconductivity observed. The results suggest that careful control of strain is essential when studying the electronic and magnetic properties of layered van der Waals solids.
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN
(2021)
Article
Nanoscience & Nanotechnology
Nathan C. Harms, Takahiro Matsuoka, Subhasis Samanta, Amanda J. Clune, Kevin A. Smith, Amanda Haglund, Erxi Feng, Huibo Cao, Jesse S. Smith, David G. Mandrus, Heung-Sik Kim, Zhenxian Liu, Janice L. Musfeldt
Summary: van der Waals solids provide ideal platforms for studying emergent properties and new states of matter. In this study, the researchers used experimental and theoretical approaches to investigate the behavior of NiPS3 under high pressure. They found multiple phase transitions and discovered a polar metal state above 23 GPa. This research not only identified a new candidate material with intriguing properties, but also suggests that pressure can tune other complex chalcogenides into this elusive state.
NPJ 2D MATERIALS AND APPLICATIONS
(2022)
Article
Multidisciplinary Sciences
Jingkai Bi, Yuki Nakamoto, Peiyu Zhang, Katsuya Shimizu, Bo Zou, Hanyu Liu, Mi Zhou, Guangtao Liu, Hongbo Wang, Yanming Ma
Summary: The substitutional alloy (La,Ce)H-9 demonstrates a significant increase in the critical temperature Tc of superconducting superhydrides, reaching up to 148 K at pressures below 1 megabar. This finding highlights the potential of alloying as an effective tool to enhance Tc in superhydrides.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Hisashi Kamimura, Takahiro Matsuoka, Hiroshi Okai, Naoki Shimizu, Shu Harada, Koji Matsuo
Summary: This study aimed to explore the association between suicidal behavior, personality traits, and brain activation in patients with mood disorders. The findings revealed that patients with a history of suicide attempts had significantly higher levels of impulsivity and hopelessness compared to healthy individuals, and showed greater brain activation in response to a threat word task. Additionally, a significant correlation between personality traits and brain activation was observed.
SCIENTIFIC REPORTS
(2022)
Article
Materials Science, Multidisciplinary
Donald Z. Chaney, John Hirtz, Evan Williams, Jacob Minnette, William F. Cureton, Eric C. O'Quinn, Xiaodong Zhao, Xiaofeng Guo, Takahiro Matsuoka, Michael Koehler, David Sprouster, Maik Lang
Summary: Complementary analytical approaches were used to study the effect of grain size on the oxidation of ZrC, including thermogravimetric analysis, differential scanning calorimetry, Raman spectroscopy, and X-ray diffraction experiments. The oxidation behavior of nanocrystalline ZrC (grain size ~20 nm) was compared to that of microcrystalline ZrC (grain size ~1 μm). The results showed that the onset of oxidation for microcrystalline ZrC was at ~380°C, while for nanocrystalline ZrC it was at ~330°C, confirming a lower critical oxidation temperature for the nanocrystalline sample.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Physics, Multidisciplinary
Hasitha W. Suriya Arachchige, William R. Meier, Madalynn Marshall, Takahiro Matsuoka, Rui Xue, Michael A. McGuire, Raphael P. Hermann, Huibo Cao, David Mandrus
Summary: Stacked vanadium kagome layers in AV(3)Sb(5) compounds have been found to exhibit unusual charge density waves. In this study, a different charge density wave phenomenon is observed in ScV6Sn6, offering further opportunities to explore density wave order in kagome lattice materials.
PHYSICAL REVIEW LETTERS
(2022)
Article
Materials Science, Multidisciplinary
Takahiro Matsuoka, Rahul Rao, Michael A. Susner, Benjamin S. Conner, Dongzhou Zhang, David Mandrus
Summary: We investigated the insulator-to-metal transition and crystal structure evolution of CoPS3 under high pressure. The compound exhibits a structural transformation accompanied by a reduction in volume and becomes metallic. The metallic CoPS3 shows a hole-dominant conduction with multiple conduction bands and displays linear magnetoresistance and incomplete high-spin low-spin transition. Our study also summarizes the comprehensive phase diagram of MPS3 compounds that metalize under pressure, including M = V, Mn, Fe, Co, Ni, and Cd.
Article
Physics, Multidisciplinary
N. Hirao, S. Kawaguchi, K. Hirose, K. Shimizu, E. Ohtani, Y. Ohishi
MATTER AND RADIATION AT EXTREMES
(2020)