Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation

Impact of Mutations in Highly Conserved Amino Acids of the HIV-1 Gag-p24 and Env-gp120 Proteins on Viral Replication in Different Genetic Backgrounds

(2014) Yi Liu et al.   PLoS One

Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8+ T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus

(2014) Hongshuo Song et al.   PLoS One

Selection bias at the heterosexual HIV-1 transmission bottleneck

(2014) J. M. Carlson et al.   SCIENCE

The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing

(2014) Jaclyn K. Mann et al.   PLoS Computational Biology

HIV-1 Vaccines: Let’s Get Physical

(2013) Nilu Goonetilleke et al.   IMMUNITY

Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design

(2013) Andrew L. Ferguson et al.   IMMUNITY

Phenotypic properties of transmitted founder HIV-1

(2013) N. F. Parrish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gag sequence variation in a human immunodeficiency virus type 1 transmission cluster influences viral replication fitness

(2012) E. F. Gijsbers et al.   JOURNAL OF GENERAL VIROLOGY

Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression

(2012) R. S. Ntale et al.   JOURNAL OF VIROLOGY

Impact of HLA-B*81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity

(2012) J. K. Wright et al.   JOURNAL OF VIROLOGY

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

(2012) Hongshuo Song et al.   Retrovirology

An Early HIV Mutation within an HLA-B*57-Restricted T Cell Epitope Abrogates Binding to the Killer Inhibitory Receptor 3DL1

(2011) S. Brackenridge et al.   JOURNAL OF VIROLOGY

Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals

(2011) D. R. Chopera et al.   JOURNAL OF VIROLOGY

Primary Infection by a Human Immunodeficiency Virus with Atypical Coreceptor Tropism

(2011) C. Jiang et al.   JOURNAL OF VIROLOGY

Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages

(2011) C. Ochsenbauer et al.   JOURNAL OF VIROLOGY

Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

(2010) T. Miura et al.   JOURNAL OF VIROLOGY

Amino-Acid Co-Variation in HIV-1 Gag Subtype C: HLA-Mediated Selection Pressure and Compensatory Dynamics

(2010) Morgane Rolland et al.   PLoS One

Modelling the Evolution and Spread of HIV Immune Escape Mutants

(2010) Helen R. Fryer et al.   PLoS Pathogens

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703–positive individuals and their transmission recipients

(2009) Hayley Crawford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

(2009) Nilu Goonetilleke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

(2009) C. F. Thobakgale et al.   JOURNAL OF VIROLOGY

Adaptation of HIV-1 to human leukocyte antigen class I

(2009) Yuka Kawashima et al.   NATURE

Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response

(2009) Ryan M. Troyer et al.   PLoS Pathogens

Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients

(2008) Paul A. Goepfert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transmission and Long-Term Stability of Compensated CD8 Escape Mutations

(2008) A. Schneidewind et al.   JOURNAL OF VIROLOGY

Reduced Viral Replication Capacity of Human Immunodeficiency Virus Type 1 Subtype C Caused by Cytotoxic-T-Lymphocyte Escape Mutations in HLA-B57 Epitopes of Capsid Protein

(2008) C. L. Boutwell et al.   JOURNAL OF VIROLOGY

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition

(2008) T. Miura et al.   JOURNAL OF VIROLOGY

Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage

(2008) Denis R. Chopera et al.   PLoS Pathogens