Integrated Moving Horizon-Based Dynamic Real-Time Optimization and Hybrid MPC-PID Control of a Direct Compaction Continuous Tablet Manufacturing Process

A Real-time Updated Model Predictive Control Strategy for Batch Processes Based on State Estimation

(2014) Guojun YANG et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

A systematic framework for onsite design and implementation of a control system in a continuous tablet manufacturing process

(2014) Ravendra Singh et al.   COMPUTERS & CHEMICAL ENGINEERING

Implementation of an advanced hybrid MPC–PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant

(2014) Ravendra Singh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A gradient-based strategy for the one-layer RTO+MPC controller

(2014) Teodoro Alamo et al.   JOURNAL OF PROCESS CONTROL

Model-based design of a plant-wide control strategy for a continuous pharmaceutical plant

(2013) Richard Lakerveld et al.   AICHE JOURNAL

Flowsheet optimization of an integrated continuous purification-processing pharmaceutical manufacturing operation

(2013) Maitraye Sen et al.   CHEMICAL ENGINEERING SCIENCE

Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production – A critical review

(2013) Ashish Kumar et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

System-wide hybrid MPC–PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction

(2013) Ravendra Singh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Multi-dimensional population balance modeling and experimental validation of continuous powder mixing processes

(2012) Maitraye Sen et al.   CHEMICAL ENGINEERING SCIENCE

Optimizing continuous powder mixing processes using periodic section modeling

(2012) Yijie Gao et al.   CHEMICAL ENGINEERING SCIENCE

An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process

(2012) Fani Boukouvala et al.   COMPUTERS & CHEMICAL ENGINEERING

Economic Nonlinear Model Predictive Control for periodic optimal operation of gas pipeline networks

(2012) Ajit Gopalakrishnan et al.   COMPUTERS & CHEMICAL ENGINEERING

Drug discovery in pharmaceutical industry: productivity challenges and trends

(2012) Ish Khanna   DRUG DISCOVERY TODAY

An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction

(2012) Ravendra Singh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

(2011) Spencer D. Schaber et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

RTO: An overview and assessment of current practice

(2011) Mark L. Darby et al.   JOURNAL OF PROCESS CONTROL

Investigation of the effect of impeller rotation rate, powder flow rate, and cohesion on powder flow behavior in a continuous blender using PEPT

(2010) Patricia M. Portillo et al.   CHEMICAL ENGINEERING SCIENCE

Characterizing continuous powder mixing using residence time distribution

(2010) Yijie Gao et al.   CHEMICAL ENGINEERING SCIENCE

Real time optimization (RTO) with model predictive control (MPC)

(2010) Glauce De Souza et al.   COMPUTERS & CHEMICAL ENGINEERING

Microstructure-based mathematical modelling and spectroscopic imaging of tablet dissolution

(2010) James A. Kimber et al.   COMPUTERS & CHEMICAL ENGINEERING

A dynamic perspective on pharmaceutical competition, drug development and cost effectiveness

(2010) Rodrigo Refoios Camejo et al.   HEALTH POLICY

ICAS-PAT: A software for design, analysis and validation of PAT systems

(2009) Ravendra Singh et al.   COMPUTERS & CHEMICAL ENGINEERING

Neighboring-extremal updates for nonlinear model-predictive control and dynamic real-time optimization

(2009) Lynn Würth et al.   JOURNAL OF PROCESS CONTROL

Analysis of Manufacturing Costs in Pharmaceutical Companies

(2008) Prabir Basu et al.   Journal of Pharmaceutical Innovation