Article
Surgery
Kristine T. Parra, John Mayberry, Niloo M. Edwards, William B. Long, Matthew J. Martin
Summary: Traumatic thoracic or chest wall hernias are rare and challenging injuries with limited literature on reliable grading systems. This article reviews relevant literature and presents a modified grading system for guiding surgical management.
AMERICAN JOURNAL OF SURGERY
(2021)
Review
Critical Care Medicine
John J. Marini, Luciano Gattinoni
Summary: Regional variations in lung and chest wall properties can modify transpulmonary pressures and suggest potential benefits of judicious application of external pressure. Observations in late-phase C-ARDS patients have shown unexpected mechanical responses to local chest wall compressions, challenging assumptions and conventional approaches to lung protection, opening avenues for further research with possible therapeutic implications.
Article
Surgery
Mitchell Skinner, Jennifer Baker, Victor Heh, Michael Goodman, Timothy Pritts, Christopher Janowak
Summary: The study found significant seasonal variation in the overall incidence of chest wall injuries, with a high-volume injury season in summer months (June-October) and a low-volume season in winter (December-April). Motorcycle accidents were a major blunt injury mechanism that changed with this seasonality, which may help guide resource utilization and injury prevention efforts.
JOURNAL OF SURGICAL RESEARCH
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Miranda Haslam, Eva Dentcheva, M. Shuja Shafqat, Roman Petrov
Summary: Chest wall reconstruction is a challenging surgery without a universally recognized gold standard. This article presents a case of using the absorbable BioBridge system for chest wall reconstruction and describes a novel complication of structural failure of the BioBridge plate, leading to prosthetic fracture and wound erosion, requiring reoperation and device removal.
ANNALS OF THORACIC SURGERY
(2022)
Review
Surgery
Lydia Masako Ferreira, Pedro Eduardo Nader Ferreira, Afranio Benedito Silva Bernardes, Gabriel Felsky dos Anjos, Ognev Meireles Cosac, Ricardo Oliva Willhelm, Wanda Elizabeth Massiere Correa, Gabriel de Almeida Arruda Felix, Felipe Contoli Isoldi
Summary: The study found that there is currently insufficient scientific evidence to support the practice of rib resection for aesthetic purposes. Only two articles were found in the literature regarding this topic, but neither provided enough cases or details of surgical techniques.
AESTHETIC PLASTIC SURGERY
(2021)
Article
Multidisciplinary Sciences
Zhoujian Tan, Xiang Zhang, Jianming Ruan, Jiqiao Liao, Fenglei Yu, Lihong Xia, Bin Wang, Chaoping Liang
Summary: The 3D-C/C composites, made of reinforced braided carbon fiber bundles and pyrolytic carbon matrix, have shown good biocompatibility and great potentials for chest wall reconstruction in artificial bones.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
David E. Meyer, John A. Harvin, Laura Vincent, Kandice Motley, Michael W. Wandling, Thaddeus J. Puzio, Laura J. Moore, Bryan A. Cotton, Charles E. Wade, Lillian S. S. Kao
Summary: The study compared the effectiveness of surgical stabilization of rib fractures (SSRFs) to nonoperative management in severe chest wall injury. The results showed that even in the absence of clinical flail chest, patients with severe chest wall injury still experienced moderate to extreme pain and impairment of usual physical activity. SSRF increased hospital length of stay and did not provide any quality of life benefit.
Article
Medicine, General & Internal
Yu-Chi Wang, Yun-Nan Lin, Chee-Yin Chai, Hsien-Pin Li, Yi-Ting Chen, Yur-Ren Kuo
Summary: This case report describes a 74-year-old man with angiomatosis who presented with a persistent mass in his lower back. The patient underwent surgery and achieved a successful recovery. The authors emphasize the importance of differential diagnosis and complete resection in preventing recurrence of angiomatosis.
Article
Respiratory System
Yojiro Yutaka, Kazuhiko Terada, Satona Tanaka, Yoshito Yamada, Akihiro Ohsumi, Daisuke Nakajima, Masatsugu Hamaji, Toshi Menju, Akihiko Yoshizawa, Hiroshi Date
Summary: Pathologically confirmed rib invasion has a significant unfavorable prognostic impact in patients with pT3N0-1 lung cancer requiring chest wall resection.
JOURNAL OF THORACIC DISEASE
(2022)
Article
Critical Care Medicine
Luca Bastia, Emanuele Rezoagli, Marcello Guarnieri, Doreen Engelberts, Clarissa Forlini, Francesco Marrazzo, Stefano Spina, Gabriele Bassi, Riccardo Giudici, Martin Post, Giacomo Bellani, Roberto Fumagalli, Laurent J. Brochard, Thomas Langer
Summary: ECC acutely reduces driving pressure (DP) in patients with COVID-19 Acute Respiratory Distress Syndrome (C-ARDS) characterized by low respiratory system compliance (C-rs < 35 mL/cmH(2)O). Although ECC does not improve oxygenation, it can help improve lung compliance and reduce pleural pressure gradient in C-ARDS patients. The benefits of ECC appear to diminish over time, and ECC produces similar effects compared to PEEP reduction.
ANNALS OF INTENSIVE CARE
(2022)
Article
Engineering, Biomedical
Mario Suazo, Joan Herrero, Gerard Fortuny, Dolors Puigjaner, Josep M. Lopez
Summary: The biomechanical response of the human ribcage to cardiopulmonary resuscitation maneuvers was studied through finite element simulations. Shifting the application area towards the tip of the breastbone reduced the force required for compression by 17% to achieve a target depth of 5 cm. However, using compression regions on the costal cartilages was found to increase the risk of rib fractures.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2022)
Review
Critical Care Medicine
John Selickman, John J. Marini
Summary: This article discusses the potential diagnostic and therapeutic value of modifying the chest wall structure to detect end-tidal hyperinflation in the respiratory system. Recent studies have shown that limiting chest wall expansion can improve tidal compliance in certain patients with ARDS who are receiving mechanical ventilatory support.
ANNALS OF INTENSIVE CARE
(2022)
Review
Critical Care Medicine
Fredric M. Pieracci, Sebastian Schubl, Mario Gasparri, Patrick Delaplain, Jordan Kirsch, Christopher Towe, Thomas W. White, SarahAnn Whitbeck, Andrew R. Doben
Summary: The study found inconsistencies in reporting within the investigational literature on surgical stabilization of rib fractures (SSRF). As a response to these inconsistencies, a set of recommendations has been proposed to standardize the reporting of original investigations in this field.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Critical Care Medicine
Jennifer M. Brewer, Rachel Huselid, Kaitlyn M. Petitpas, Vijay Jayaraman, T. Russel Hill, Chasen Greig, Carol McGuiness, Erin McLaughlin, Stephanie C. Montgomery, David S. Shapiro, Manuel Moutinho, Andrew R. Doben
Summary: This study aims to investigate the impact of Chest Wall Injury and Reconstructive Centers (CWIRC) establishment on patient outcomes. The results showed that there was an increase in the number of patients treated at CWIRC, and early diagnosis and triage led to more admissions to higher levels of care, but there were no significant improvements in outcomes.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Review
Medicine, General & Internal
Kent Carpenter, Ali Etemady-Deylamy, Victoria Costello, Mohammad Khasawneh, Robin Chamberland, Katherine Tian, Maureen Donlin, Brenda Moreira-Walsh, Emily Reisenbichler, Getahun Abate
Summary: Fingolimod use has been associated with various cryptococcal infections. We report a unique case of cryptococcal chest wall mass and rib osteomyelitis related to fingolimod use. The patient showed significant improvement after treatment.
FRONTIERS IN MEDICINE
(2022)
Article
Physiology
Edgardo D'Angelo, Edoardo Calderini, Mario Tavola, Matteo Pecchiari
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2019)
Review
Respiratory System
Pierachille Santus, Matteo Pecchiari, Francesco Tursi, Vincenzo Valenti, Marina Saad, Dejan Radovanovic
CANADIAN RESPIRATORY JOURNAL
(2019)
Review
Medicine, General & Internal
Konstantinos Loverdos, Georgios Bellos, Louiza Kokolatou, Ioannis Vasileiadis, Evangelos Giamarellos, Matteo Pecchiari, Nikolaos Koulouris, Antonia Koutsoukou, Nikoletta Rovina
JOURNAL OF CLINICAL MEDICINE
(2019)
Article
Physiology
Edgardo D'Angelo, Antonia Koutsoukou, Patrizia Della Valle, Guendalina Gentile, Matteo Pecchiari
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2020)
Review
Critical Care Medicine
Pierachille Santus, Dejan Radovanovic, Matteo Pecchiari, Matteo Ferrando, Francesco Tursi, Vincenzo Patella, Fulvio Braido
Article
Physiology
Matteo Pecchiari, Dejan Radovanovic, Camilla Zilianti, Laura Saderi, Giovanni Sotgiu, Edgardo D'Angelo, Pierachille Santus
JOURNAL OF APPLIED PHYSIOLOGY
(2020)
Article
Physiology
Edgardo d'Angelo, Matteo Pecchiari, Francois Bellemare, Gabriele Cevenini, Paolo Barbini
Summary: In an obstructive sleep apnea rabbit model, heliox does not eliminate tidal inspiratory flow limitation (IFL), but enhances inspiratory flow and tidal volume, with varying effects among different animals. Predicting positive response to heliox is not possible based on pre-IFL characteristics, but rather on mechanical and geometrical features of the upper airway collapsible segment, as indicated by modeling simulation.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Patrizia Benzoni, Giorgia Bertoli, Federica Giannetti, Chiara Piantoni, Raffaella Milanesi, Matteo Pecchiari, Andrea Barbuti, Mirko Baruscotti, Annalisa Bucchi
Summary: The studies on the If current have revealed its novel functions in various systems and organs, such as sour taste transduction, hormone secretion, and cellular respiration. Additionally, it plays an important role in controlling stem cell cycle and bioelectrical signals.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
(2021)
Biographical-Item
Physiology
Edgardo d'Angelo, Roberto Galli, Matteo Pecchiari, Cristina Porta, Chiara Sironi, Luciano Zocchi
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2021)
Review
Medicine, General & Internal
Camilla Zilianti, Pierachille Santus, Matteo Pecchiari, Edgardo D'Angelo, Dejan Radovanovic
Summary: Body plethysmography has been instrumental in diagnosing respiratory diseases and following up on patients. Research has shown that estimation of alveolar pressure by electronically-compensated plethysmographs may provide valuable information about the mechanics of the respiratory system, particularly in predicting expiratory flow limitation.
Article
Physiology
Edgardo D'Angelo, Dejan Radovanovic, Paolo Barbini, Pierachille Santus, Matteo Pecchiari
Summary: The study found that Rexp/Rins can be used to detect tEFL in COPD patients, with higher values before measurement indicating a higher likelihood of tEFL, and the predictive ability slightly declining but remaining elevated after measurement.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2022)
Review
Medicine, General & Internal
Pierachille Santus, Dejan Radovanovic, Marina Saad, Camilla Zilianti, Silvia Coppola, Davide Alberto Chiumello, Matteo Pecchiari
Summary: Acute dyspnea is a common symptom that often leads to emergency room evaluation, and its prognosis is important and should be carefully evaluated. The differential diagnosis of dyspnea is challenging due to its lack of specificity and the loose relationship between its intensity and the severity of the underlying condition. Recent evidence suggests that lung ultrasound and echocardiography are valuable diagnostic tools for assessing heart, lung, or extra-pulmonary involvement in patients with dyspnea. Non-invasive respiratory support modalities like high-flow nasal oxygen and continuous positive airway pressure have gained considerable interest for effectively treating dyspnea without invasive mechanical ventilation. This clinical review focuses on the pathophysiology, clinical presentation, evaluation, and non-invasive respiratory support options for acute dyspnea patients.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Physiology
Matteo Pecchiari, Konstantinos Pontikis, Emmanouil Alevrakis, Ioannis Vasileiadis, Maria Kompoti, Antonia Koutsoukou
Summary: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The hemodynamic phenotype is highly variable and influenced by multiple factors. The dissociation between microcirculation and macrocirculation may explain the limited success of therapeutic interventions targeting typical hemodynamic parameters.
COMPREHENSIVE PHYSIOLOGY
(2021)
Meeting Abstract
Respiratory System
Dejan Radovanovic, Matteo Pecchiari, Marina Saad, Pierachille Santus
EUROPEAN RESPIRATORY JOURNAL
(2020)
Meeting Abstract
Respiratory System
Dejan Radovanovic, Camilla Zilianti, Andrea Cristiano, Tommaso Pilocane, Paolo Gaboardi, Andrea Airoldi, Matteo Pecchiari, Pierachille Santus
EUROPEAN RESPIRATORY JOURNAL
(2019)
Article
Physiology
Alyssa R. Mickle, Jesus D. Penaloza-Aponte, Richard Coffey, Natale A. Hall, David Baekey, Erica A. Dale
Summary: Closed-loop epidural stimulation (CL-ES) can improve respiratory deficits caused by cervical spinal cord injury, restoring diaphragm activity and enhancing contralateral activity. This treatment has the potential to lead to lasting recovery and device independence.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Shawn Miller Jr, Edgar Juarez Lopez, Jessica M. L. Grittner, Brendan J. Dougherty
Summary: This study tested the impact of CO2 supplementation at different concentrations on ventilatory long-term facilitation (vLTF) in rats and found that 2% CO2 supplementation during and after acute, intermittent hypoxia (AIH) was sufficient to maintain isocapnia and induce significant vLTF.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Behnam Vafadari, Yoshitaka Oku, Charlotte Tacke, Ali Harb, Swen Huelsmann
Summary: The preBo·tzinger Complex (preBo·tC) in the brainstem plays a critical role in generating respiratory rhythm. This study aimed to investigate the activity of inhibitory glycinergic neurons in the preBo·tC of anesthetized mice. Using juxtacellular recordings and optogenetic activation, the researchers were able to identify and characterize the activity pattern of these inhibitory neurons in relation to the breathing rhythm.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Stephen M. Johnson, Maia G. Gumnit, Sarah M. Johnson, Tracy L. Baker, Jyoti J. Watters
Summary: Low-level activation of mu-opioid receptors can increase the amplitude of inspiratory bursts in neonatal rat brainstem-spinal cord preparations. Endomorphin-2, an endogenous ligand for these receptors, was found to have similar effects. Disinhibition of inhibitory synaptic transmission may not be involved in the changes induced by endomorphin-2, and different mechanisms may underlie the increase in burst amplitude and decrease in burst frequency.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Raphael Martins de Abreu, Beatrice Cairo, Patricia Rehder-Santos, Claudio Donisete da Silva, Etore De Favari Signini, Juliana Cristina Milan-Mattos, Camila Akemi Sakaguchi, Aparecida Maria Catai, Alberto Porta
Summary: The purpose of this study was to determine the association between exercise capacity based on peak oxygen uptake (VO2peak) and resting cardiorespiratory coupling (CRC) levels. The results showed that resting CRC values were associated with exercise capacity in athletes but not in non-athletes.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Sarah M. Russel, Raluca E. Gosman, Katherine Gonzalez, Joshua Wright, Dennis O. Frank-Ito
Summary: This study aimed to characterize the response of different nasal morphologies to airflow-related variables during rapid/deep inspiration. The results showed that notched nasal vestibules had higher resistance values and airflow velocities, while standard nasal vestibules had higher mucosal heat flux. Different nasal phenotypes may predispose individuals to exercise-induced rhinitis.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Ivan Poliacek, Lukas Martvon, Michal Simera, Marcel Veternik, Jakub Misek, Lucia Cibulkova, Kimberly E. Iceman, Donald C. Bolser, Teresa Pitts
Summary: An animal model study evaluated the effects of an abdominal incision on cough and swallow, revealing that abdominal wall manipulations can increase pharyngeal muscle activity during swallow without affecting the cough reflex. Swallowing tended to occur more during the inspiratory phase. The results highlight the important role of abdominal wall sensory feedback in regulating swallow motor patterns.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Rui Yu, Tatsuma Okazaki, Yuzhuo Ren, Junko Okuyama, Satoru Ebihara, Shin-Ichi Izumi
Summary: Body postures significantly influence respiratory muscle force, cough pressure, subjective ease of coughing, and pulmonary function. The 60-degree semi-recumbent posture and sitting posture show better results compared to the supine posture.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Suzuna Sato, Koji Ishida, Noriko I. Tanaka, Keisho Katayama
Summary: Respiratory muscle endurance training has beneficial effects on whole-body endurance performance. A novel high-intensity interval (HII) protocol is found to enhance the efficacy of respiratory muscle training programs.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Letter
Physiology
R. Arieli
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Correction
Physiology
Ivan Poliacek, Michal Simera, Marcel Veternik, Zuzana Kotmanova, Teresa Pitts, Jan Hanacek, Jana Plevkova, Peter Machac, Nadezda Visnovcova, Jakub Misek, Jan Jakus
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Dimitrios I. Bourdas, Nickos D. Geladas
Summary: This study examined the effects of breath-hold training on the performance of novice and elite breath-hold divers. The results showed that breath-hold training significantly improved red blood cell concentration, hemoglobin oxygen saturation steady state duration, and breath-hold time in novice divers. Elite divers had better breath-hold performance and higher peak mean arterial pressure compared to novices. The study suggests that breath-hold training can enhance the performance of divers.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
