Review
Agronomy
Nitin Sharma, Meenakshi Thakur, Pavithra Suryakumar, Purbali Mukherjee, Ali Raza, Channapatna S. Prakash, Anjali Anand
Summary: Respiration and photosynthesis in plants are negatively affected by elevated temperatures, leading to disruptions in the plant's carbon economy. This review discusses the mechanistic insight into the heat stress-induced mitochondrial dysfunction in plants, which affects dark respiration. The role of hormones in regulating retrograde signaling is highlighted, and different strategies to reduce carbon loss under high temperatures are proposed, including selecting genotypes with low respiration rates and using genome editing tools.
Article
Biology
Andrew M. Greenfield, Felipe Gorini Pereira, William R. Boyer, Marc R. Apkarian, Matthew R. Kuennen, Trevor L. Gillum
Summary: The study found that hot water immersion (HWI) as a heat acclimation strategy induced greater thermal strain compared to exercise-heat acclimation (EHA) at equivalent temperatures. However, this greater thermal strain did not result in significant differences in cardiovascular, thermoregulatory, or perceptual variables between the two interventions. This suggests that three sessions of HWI may be a potential means to lower heart rate, core temperature, and perceptual strain during exercise in the heat.
JOURNAL OF THERMAL BIOLOGY
(2021)
Review
Plant Sciences
Myrthe Praat, Ive De Smet, Martijn van Zanten
Summary: Plants need to adapt to changing temperature conditions in their environment to survive and thrive. Various protein kinases are involved in plant responses to cold acclimation and heat stress, but their roles in mild temperature changes remain poorly understood. Understanding plant temperature responses is crucial for developing thermotolerant crops.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Environmental Sciences
Yichen Zhang, Shilong Piao, Yan Sun, Brendan M. Rogers, Xiangyi Li, Xu Lian, Zhihua Liu, Anping Chen, Josep Penuelas
Summary: Vegetation productivity in the Northern Hemisphere has increased under climate change, but the correlations with summer temperature are projected to decrease by the end of the century. This could have implications for the terrestrial carbon sink. The relationship between summer vegetation productivity and temperature will become negative in temperate and boreal regions by the late twenty-first century, while Arctic vegetation productivity continues to increase with further summer warming. This suggests that photosynthetic thermal acclimation may mitigate the negative impacts of future warming on vegetation.
NATURE CLIMATE CHANGE
(2022)
Article
Sport Sciences
Paul S. R. Goods, Peta Maloney, Joanna Miller, Denise Jennings, Jack Fahey-Gilmour, Peter Peeling, Brook Galna
Summary: Wearable temperature sensors have limitations in accurately measuring core temperature at elevated levels, making them unsuitable for assessing core temperature during exercise in hot conditions.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Physiology
Luis Gustavo A. Patrone, Aline C. G. Rocha, Mariana Bernardes-Ribeiro, Gleyce Lopes-da-Costa, Marcos Macari, Kenia C. Bicego, Luciane H. Gargaglioni
Summary: Global warming has significant effects on animal physiology, especially for fast-growing species. In this study, we investigated the impact of thermal manipulation during incubation on the adaptive response of chicks to heat stress. Our results showed that females are more sensitive to thermal manipulation during incubation and that the manipulation does not improve the adaptive response of chicks.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2023)
Article
Anesthesiology
Andrew Donnelly, Stuart Dolling
Summary: This article discusses the definition and function of a breathing system, as well as the key elements and classification systems of anaesthetic breathing systems and their clinical application. It also provides a brief overview of the use and function of carbon dioxide absorbers.
ANAESTHESIA AND INTENSIVE CARE MEDICINE
(2022)
Article
Construction & Building Technology
Enrico Sisti, Antonio Rossetti, Silvia Minetto, Sergio Marinetti, Giacomo Tosato, Alessandro Beghi, Mirco Rampazzo
Summary: Modelling and simulation tools are essential for tackling the complexity of industrial applications and accelerating the innovation process by exploring and utilizing efficient, reliable, and sustainable solutions. This paper presents a dynamic model of a chiller system using carbon dioxide as a refrigerant, which is validated against experimental data and can be used to evaluate different control strategies. The results highlight the potential benefits of integrating the model into Computer-aided Control System Design (CACSD) software tools.
ENERGY AND BUILDINGS
(2023)
Article
Neurosciences
Nasimi A. Guluzade, Joshua D. Huggard, James Duffin, Daniel A. Keir
Summary: The interaction between central and peripheral chemoreceptors in driving human breathing remains controversial. In this study, we measured the sensitivity of the peripheral chemoreflex to hypoxia (PChS) at different levels of isocapnic CO2 tensions (P-CO2) in order to determine the relationship between PChS and central P-CO2. The results showed that PChS increased linearly with P-ETCO2, indicating an additive central-peripheral chemoreflex response.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Thermodynamics
Qi Cui, Dianhang Wei, Enyuan Gao, Zhongbin Zhang, Xiaosong Zhang
Summary: A compact water-cooled subcooler-assisted carbon dioxide heat pump is designed in this paper to improve the energy efficiency. The experimental results show that the cooling performance is significantly improved, with an increase of 20.2% in cooling capacity and 31.5% in cooling coefficient of performance. However, the heating performance is somewhat degraded, but can be mitigated by a control strategy.
ENERGY CONVERSION AND MANAGEMENT
(2023)
Article
Meteorology & Atmospheric Sciences
Xinhua Zhou, Tian Gao, Eugene S. Takle, Xiaojie Zhen, Andrew E. Suyker, Tala Awada, Jane Okalebo, Jiaojun Zhu
Summary: Air temperature is crucial in the flux exchanges between the atmosphere and ecosystems. The accuracy of temperature measurement depends on the method used and the accuracy of key variables. This study derived an equation to compute temperature using sonic temperature and water vapor mixing ratio, which is inherently error-free. Based on current specifications, the accuracy of equation-computed temperature is within +/-1.01 K. Improvements in measurement technologies, particularly for sonic temperature, can further enhance the accuracy.
ATMOSPHERIC MEASUREMENT TECHNIQUES
(2022)
Article
Pharmacology & Pharmacy
Yurena Luengo, Zamira V. Diaz-Riascos, David Garcia-Soriano, Francisco J. Teran, Emilio J. Artes-Ibanez, Oihane Ibarrola, Alvaro Somoza, Rodolfo Miranda, Simo Schwartz, Ibane Abasolo, Gorka Salas
Summary: The clinical implementation of magnetic hyperthermia has been slow due to the challenges in producing magnetic nanoparticles with controlled properties and controlling the temperature at the target tissue. This study successfully prepared iron oxide superparamagnetic nanoparticles and demonstrated that the rise in temperature can be controlled by modulating the field intensity during in vivo magnetic hyperthermia protocols. This simple procedure can be easily implemented by researchers or practitioners working in magnetic hyperthermia therapies.
Article
Clinical Neurology
Simon D. Herkenrath, Marcel Treml, Lars Hagmeyer, Sandhya Matthes, Winfried J. Randerath
Summary: This study compared characteristics of obese patients with eucapnic obstructive sleep apnea, obesity-related sleep hypoventilation, or obesity hypoventilation syndrome to identify the major determinants of hypoventilation. The results suggest that hypercapnic ventilatory response is the major determinant of obesity-associated hypoventilation.
Article
Neurosciences
Olivia K. Harrison, Laura Koechli, Stephanie Marino, Roger Luechinger, Franciszek Hennel, Katja Brand, Alexander J. Hess, Stefan Fraessle, Sandra Iglesias, Fabien Vinckier, Frederike H. Petzschner, Samuel J. Harrison, Klaas E. Stephan
Summary: The study found that anxiety is linked to interoception at different processing levels, particularly in the domain of breathing. The anterior insula plays an important role in representing and updating models of the body, and anxiety traits can impact brain activity related to prediction certainty.
Article
Chemistry, Inorganic & Nuclear
PeiPei Zhou, Zitong Song, Xia Zhou, Zhuoyi Cheng, Xue Wang, DongMei Wang
Summary: Flexible metal-organic frameworks (FMOFs) were successfully constructed using divalent metal ions and multifunctional aromatic N,O-donor ligands. Compound 2 and 3 showed exceptional adsorption performance for Acetylene (C2H2), which can be attributed to the innovative structure and solvent-induced effect.
INORGANIC CHEMISTRY
(2023)
Article
Respiratory System
Xavier Waltz, Andrew E. Beaudin, Elise Belaidi, Jill Raneri, Jean-Louis Pepin, Vincent Pialoux, Patrick J. Hanly, Samuel Verges, Marc J. Poulin
Summary: Studies on rats and human patients have shown that intermittent hypoxia and obstructive sleep apnoea do not directly cause alterations in hemorheology. Despite the presence of oxidative stress or increased sensitivity to reactive oxygen species, no significant changes in hemorheological properties were observed.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Neurosciences
Arsenije Subotic, Cheryl R. McCreary, Feryal Saad, Amanda Nguyen, Ana Alvarez-Veronesi, Angela M. Zwiers, Anna Charlton, Andrew E. Beaudin, Zahinoor Ismail, G. Bruce Pike, Eric E. Smith
Summary: This study found that global cortical thickness was lower in CAA patients compared to healthy controls, but slightly higher than in AD patients. In the AD signature region, cortical thickness in CAA was also lower compared to the healthy controls. Within the CAA group, lower cortical thickness was associated with lower memory scores and higher white matter hyperintensity volume.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Clinical Neurology
Andrew E. Beaudin, Jill K. Raneri, Najib T. Ayas, Robert P. Skomro, Eric E. Smith, Patrick J. Hanly
Summary: This study investigated the impact of hypercapnia on cognitive function in severe sleep-disordered breathing (OSA accompanied by hypoventilation). The results showed that awake hypoventilation is associated with greater deficits in cognitive function in patients with severe sleep-disordered breathing.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2022)
Review
Neurosciences
Andrew E. Beaudin, Patrick J. Hanly, Jill K. Raneri, Magdy Younes, Matiram Pun, Todd J. Anderson, Marc J. Poulin
Summary: Exposure to intermittent hypoxia (IH) is believed to increase the risk of cerebrovascular and cardiovascular disease, but sleep accompanied by IH does not significantly alter vascular responses to hypoxia and hypercapnia in healthy young individuals. However, IH sleep does lead to an increased heart rate response to hypoxia upon waking.
EXPERIMENTAL NEUROLOGY
(2022)
Article
Clinical Neurology
Andrew E. Beaudin, Jill K. Raneri, Sofia B. Ahmed, A. J. Marcus Hirsch Allen, Andrhea Nocon, Teresa Gomes, Simon Gakwaya, Frederic Series, John Kimoff, Robert P. Skomro, Najib T. Ayas, Patrick J. Hanly
Summary: The study revealed that patients with moderate to severe obstructive sleep apnea (OSA) have an increased risk of chronic kidney disease (CKD) progression, and most patients are unaware of their abnormal kidney function.
Article
Clinical Neurology
Romella Durrani, Meng Wang, Emily Cox, Elisabeth Irving, Feryal Saad, Cheryl R. McCreary, Andrew E. Beaudin, Myrlene Gee, Krista Nelles, Tolulope T. Sajobi, Zahinoor Ismail, Richard Camicioli, Eric E. Smith
Summary: Neuroimaging biomarkers, including altered white matter diffusivity, cerebrovascular reactivity, and atrophy, are closely associated with cognitive dysfunction in cerebral amyloid angiopathy (CAA).
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Clinical Neurology
Magdy K. Younes, Andrew E. Beaudin, Jill K. Raneri, Beth J. Gerardy, Patrick J. Hanly
Summary: Long-term adherence with PAP therapy can be predicted from PSG scoring and measures of sleep depth in patients with obstructive sleep apnea, which may facilitate a precision-based approach to PAP management.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2022)
Article
Clinical Neurology
Andrew E. Beaudin, Cheryl R. McCreary, Erin L. Mazerolle, Myrlene Gee, Breni Sharma, Arsenije Subotic, Angela M. Zwiers, Emily Cox, Krista Nelles, Anna Charlton, Richard Frayne, Zahinoor Ismail, Christian Beaulieu, Glen C. Jickling, Richard M. Camicioli, G. Bruce Pike, Eric E. Smith
Summary: This study found that reduced cerebrovascular reactivity is a core feature of cerebral amyloid angiopathy (CAA), and it is associated with white matter hyperintensity volume and cognitive function. This finding could provide additional biomarkers for assessing the severity of the disease and cognitive impairment.
Article
Clinical Neurology
Andrew E. Beaudin, Jill K. Raneri, Sofia Ahmed, A. J. Hirsch Allen, Andrhea Nocon, Teresa Gomes, Simon Gakwaya, Frederic Series, John R. Kimoff, Robert Skomro, Najib Ayas, Patrick J. Hanly
Summary: This study investigated the impact of obstructive sleep apnea (OSA) and insomnia with short sleep duration on the risk of chronic kidney disease (CKD) progression. The results showed that insomnia with short sleep duration does not increase the risk of CKD progression and does not further increase the risk associated with moderate-to-severe OSA.
Letter
Critical Care Medicine
Andrew E. Beaudin, Jill K. Raneri, A. J. Marcus Hirsch Allen, Frederic Series, R. John Kimoff, Robert P. Skomro, Najib T. Ayas, Diego R. Mazzotti, Brendan T. Keenan, Patrick J. Hanly
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Clinical Neurology
Chih-Hao Chen, Mark D. Peterson, C. David Mazer, Makoto Hibino, Andrew E. Beaudin, Michael W. A. Chu, Francois Dagenais, Hwee Teoh, Adrian Quan, Jeffrey Dickson, Subodh Verma, Eric E. Smith
Summary: This study investigated the frequency and distribution of new ischemic brain lesions detected by diffusion-weighted imaging after aortic arch surgery. Results showed that 70% of the participants had 391 new lesions, with half of them in the middle cerebral artery territory. Factors such as preoperative white matter hyperintensity, lower intraoperative temperature, and older age were associated with the occurrence of new ischemic lesions.
Article
Clinical Neurology
Magdy Younes, Bethany Gerardy, Eleni Giannouli, Jill Raneri, Najib T. Ayas, Robert Skomro, R. John Kimoff, Frederic Series, Patrick J. Hanly, Andrew Beaudin
Summary: The response of sleep depth to CPAP in patients with OSA is unpredictable. Only three out of the nine ORP patterns are associated with OSA. The study aims to determine if sleep depth improves exclusively in patients with these three ORP patterns on CPAP therapy.
Article
Respiratory System
Chitra Lal, Indu Ayappa, Najib Ayas, Andrew E. Beaudin, Camilla Hoyos, Clete A. Kushida, Marta Kaminska, Anna Mullins, Sharon L. Naismith, Ricardo S. Osorio, Craig L. Phillips, Ankit Parekh, Katie L. Stone, Arlener D. Turner, Andrew W. Varga
Summary: Emerging evidence suggests that obstructive sleep apnea (OSA) is a potential risk factor for preclinical Alzheimer's disease (AD). A workshop was conducted to summarize the current knowledge, identify research gaps, and suggest future directions. It is important to interpret cognitive screening tests cautiously in patients with OSA, and neuroimaging has limitations in measuring disease chronicity. Continuous positive airway pressure (CPAP) shows potential cognitive benefits, but the results vary across studies. OSA may have negative impacts on AD and other forms of dementia.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2022)
Article
Neuroimaging
Ibrahim Shaikh, Christian Beaulieu, Myrlene Gee, Cheryl R. McCreary, Andrew E. Beaudin, Diana Valdes-Cabrera, Eric E. Smith, Richard Camicioli
Summary: Diffusion tensor imaging metrics of the fornix were compared between patients with cerebral amyloid angiopathy (CAA), Alzheimer's disease (AD), Mild Cognitive Impairment (MCI), and healthy controls. The study found significant diffusion changes in the fornix of CAA, AD, and MCI patients compared to controls, suggesting differences in the mechanisms of fornix diffusion abnormalities between CAA and AD/MCI.
NEUROIMAGE-CLINICAL
(2022)
Article
Respiratory System
Andrew E. Beaudin, Jill K. Raneri, Najib T. Ayas, Robert P. Skomro, Nurit Fox, A. J. Marcus Hirsch Allen, Matthew W. Bowen, Andrhea Nocon, Emma J. Lynch, Meng Wang, Eric E. Smith, Patrick J. Hanly
Summary: The prevalence of mild cognitive impairment (MCI) is high in patients referred to sleep clinics for obstructive sleep apnea (OSA), especially among older males with moderate to severe OSA and vascular comorbidities. Moderate to severe OSA is an independent risk factor for MCI, with higher odds for cognitive impairment compared to patients with no OSA.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
Article
Physiology
Alyssa R. Mickle, Jesus D. Penaloza-Aponte, Richard Coffey, Natale A. Hall, David Baekey, Erica A. Dale
Summary: Closed-loop epidural stimulation (CL-ES) can improve respiratory deficits caused by cervical spinal cord injury, restoring diaphragm activity and enhancing contralateral activity. This treatment has the potential to lead to lasting recovery and device independence.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Shawn Miller Jr, Edgar Juarez Lopez, Jessica M. L. Grittner, Brendan J. Dougherty
Summary: This study tested the impact of CO2 supplementation at different concentrations on ventilatory long-term facilitation (vLTF) in rats and found that 2% CO2 supplementation during and after acute, intermittent hypoxia (AIH) was sufficient to maintain isocapnia and induce significant vLTF.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Behnam Vafadari, Yoshitaka Oku, Charlotte Tacke, Ali Harb, Swen Huelsmann
Summary: The preBo·tzinger Complex (preBo·tC) in the brainstem plays a critical role in generating respiratory rhythm. This study aimed to investigate the activity of inhibitory glycinergic neurons in the preBo·tC of anesthetized mice. Using juxtacellular recordings and optogenetic activation, the researchers were able to identify and characterize the activity pattern of these inhibitory neurons in relation to the breathing rhythm.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Stephen M. Johnson, Maia G. Gumnit, Sarah M. Johnson, Tracy L. Baker, Jyoti J. Watters
Summary: Low-level activation of mu-opioid receptors can increase the amplitude of inspiratory bursts in neonatal rat brainstem-spinal cord preparations. Endomorphin-2, an endogenous ligand for these receptors, was found to have similar effects. Disinhibition of inhibitory synaptic transmission may not be involved in the changes induced by endomorphin-2, and different mechanisms may underlie the increase in burst amplitude and decrease in burst frequency.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Raphael Martins de Abreu, Beatrice Cairo, Patricia Rehder-Santos, Claudio Donisete da Silva, Etore De Favari Signini, Juliana Cristina Milan-Mattos, Camila Akemi Sakaguchi, Aparecida Maria Catai, Alberto Porta
Summary: The purpose of this study was to determine the association between exercise capacity based on peak oxygen uptake (VO2peak) and resting cardiorespiratory coupling (CRC) levels. The results showed that resting CRC values were associated with exercise capacity in athletes but not in non-athletes.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Sarah M. Russel, Raluca E. Gosman, Katherine Gonzalez, Joshua Wright, Dennis O. Frank-Ito
Summary: This study aimed to characterize the response of different nasal morphologies to airflow-related variables during rapid/deep inspiration. The results showed that notched nasal vestibules had higher resistance values and airflow velocities, while standard nasal vestibules had higher mucosal heat flux. Different nasal phenotypes may predispose individuals to exercise-induced rhinitis.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Ivan Poliacek, Lukas Martvon, Michal Simera, Marcel Veternik, Jakub Misek, Lucia Cibulkova, Kimberly E. Iceman, Donald C. Bolser, Teresa Pitts
Summary: An animal model study evaluated the effects of an abdominal incision on cough and swallow, revealing that abdominal wall manipulations can increase pharyngeal muscle activity during swallow without affecting the cough reflex. Swallowing tended to occur more during the inspiratory phase. The results highlight the important role of abdominal wall sensory feedback in regulating swallow motor patterns.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Rui Yu, Tatsuma Okazaki, Yuzhuo Ren, Junko Okuyama, Satoru Ebihara, Shin-Ichi Izumi
Summary: Body postures significantly influence respiratory muscle force, cough pressure, subjective ease of coughing, and pulmonary function. The 60-degree semi-recumbent posture and sitting posture show better results compared to the supine posture.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Suzuna Sato, Koji Ishida, Noriko I. Tanaka, Keisho Katayama
Summary: Respiratory muscle endurance training has beneficial effects on whole-body endurance performance. A novel high-intensity interval (HII) protocol is found to enhance the efficacy of respiratory muscle training programs.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Letter
Physiology
R. Arieli
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Correction
Physiology
Ivan Poliacek, Michal Simera, Marcel Veternik, Zuzana Kotmanova, Teresa Pitts, Jan Hanacek, Jana Plevkova, Peter Machac, Nadezda Visnovcova, Jakub Misek, Jan Jakus
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Dimitrios I. Bourdas, Nickos D. Geladas
Summary: This study examined the effects of breath-hold training on the performance of novice and elite breath-hold divers. The results showed that breath-hold training significantly improved red blood cell concentration, hemoglobin oxygen saturation steady state duration, and breath-hold time in novice divers. Elite divers had better breath-hold performance and higher peak mean arterial pressure compared to novices. The study suggests that breath-hold training can enhance the performance of divers.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
