Article
Medicine, General & Internal
Paula Duarte D'Ambrosio, Pedro Henrique Xavier Nabuco de Araujo, Eserval Rocha Junior, Mauro Razuk Filho, Paulo Manuel Pego-Fernandes, Ricardo Mingarini Terra
Summary: The study aimed to identify the risk factors for post-pleurodesis empyema after talc slurry pleurodesis. The results showed that antibiotic therapy prior to pleurodesis was an independent risk factor for the development of empyema, and patients with long-duration chest tube placement and incomplete lung expansion also had a higher risk of empyema.
Review
Biology
Sean P. F. Foley, John Scott Parrish
Summary: Pleural space infections have been a well-recognized clinical syndrome for over 4000 years and continue to cause significant morbidity and mortality worldwide. Our understanding of the causative pathophysiology has greatly expanded over the last few decades, as have our treatment options. This paper aims to review recent updates in our understanding of pleural space infections and provide updates on treatment modalities.
Article
Infectious Diseases
Ling Ai, Jingyuan Li, Ting Ye, Wenjun Wang, Yuying Li
Summary: This article reports a case of exudative pleural effusion caused by lung fluke infection in a young male. It highlights that lung fluke infection is often overlooked as a cause of pleural effusion. Eosinophilia may serve as a marker for infection, and serological tests can aid in confirming the diagnosis.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Critical Care Medicine
Jason Akulian, Eihab O. Bedawi, Hawazin Abbas, Christine Argento, David T. Arnold, Akshu Balwan, Hitesh Batra, Juan Pablo Uribe Becerra, Adam Belanger, Kristin Berger, Allen Cole Burks, Jiwoon Chang, Ara A. Chrissian, David M. DiBardino, Xavier Fonseca Fuentes, Yaron B. Gesthalter, Christopher R. Gilbert, Kristen Glisinski, Mark Godfrey, Jed A. Gorden, Horiana Grosu, Mridul Gupta, Fayez Kheir, Kevin C. Ma, Adnan Majid, Fabien Maldonado, Nick A. Maskell, Hiren Mehta, Joshua Mercer, John Mullon, Darlene Nelson, Elaine Nguyen, Edward M. Pickering, Jonathan Puchalski, Chakravarthy Reddy, Alberto E. Revelo, Lance Roller, Ashutosh Sachdeva, Trinidad Sanchez, Priya Sathyanarayan, Roy Semaan, Michal Senitko, Samira Shojaee, Ryan Story, Jeffrey Thiboutot, Momen Wahidi, Candice L. Wilshire, Diana Yu, Aline Zouk, Najib M. Rahman, Lonny Yarmus
Summary: Combination intrapleural fibrinolytic and enzyme therapy (IET) carries a low overall bleeding risk in pleural infection. The concurrent use of therapeutic anticoagulation increases the bleeding rates, which can be mitigated by withholding anticoagulation before treatment. Parameters related to higher bleeding risk have been identified.
Article
Respiratory System
Alexandra Townsend, Harsha Raju, Krystina A. Serpa, Rachel Pruett, Syed S. Razi, Francisco A. Tarrazzi, Catherine M. Tami, Mark I. Block
Summary: This study retrospectively reviewed the use of low dose tPA with a 12-hour dwell time for the management of complex pleural effusions. The results suggest that this regimen may be as effective as the standard daily tPA and DNAse regimen.
BMC PULMONARY MEDICINE
(2022)
Article
Infectious Diseases
Yoshiki Shiraishi, Kirill Kryukov, Katsuyoshi Tomomatsu, Fumio Sakamaki, Shigeaki Inoue, So Nakagawa, Tadashi Imanishi, Koichiro Asano
Summary: This study aimed to identify probable causative bacteria in pleural empyema/parapneumonic effusions by combining 16S rRNA gene amplification and next-generation sequencing (NGS). NGS results were discordant with culture results in some patients who had been treated with antibiotics. Total and specific bacterial loads calculated using semi-quantitative PCR could efficiently distinguish infectious effusions from non-infectious effusions.
INFECTIOUS DISEASES
(2021)
Article
Critical Care Medicine
Srinivas R. Mummadi, James K. Stoller, Rocio Lopez, Karthik Kailasam, Colin T. Gillespie, Peter Y. Hahn
Summary: This study investigated the epidemiologic measures related to adult pleural diseases in the United States from 2007 to 2016. Significant trends and changes in various pleural diseases were observed, suggesting opportunities for improvement in their management.
Article
Respiratory System
David T. Arnold, Emma Tucker, Anna Morley, Alice Milne, Louise Stadon, Sonia Patole, George W. Nava, Steven P. Walker, Nick A. Maskell
Summary: Therapeutic thoracentesis may reduce hospital stay in pleural infection.
BMC PULMONARY MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Claudio Sorino, Michele Mondoni, Filippo Lococo, Giampietro Marchetti, David Feller-Kopman
Summary: Pleural effusion can complicate acute pulmonary infection, with potential stages of exudative, fibropurulent, and organized effusion. The fibropurulent stage often requires invasive procedures for resolution. Treatment options include antibiotics, invasive procedures, and fibrinolytic therapy.
RESPIRATORY MEDICINE
(2022)
Article
Immunology
Johannes Forster, Giuseppina Piazza, David Goettler, Daniel Kemmling, Christoph Schoen, Markus Rose, Andrea Streng, Johannes G. Liese
Summary: The study found that prehospital antibiotic therapy (PH-ABT) in children with PPE/PE shortened the hospital length of stay, reduced the rate of intensive care unit admission and infectious complications, but also decreased the overall rate of bacterial pathogen detection. However, PH-ABT did not affect the overall duration of the disease.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Article
Immunology
Tadashi Hoshino, Daisuke Nishima, Mayumi Enseki, Naoki Umehara, Chie Fukasawa, Naruhiko Ishiwada
Summary: This nationwide survey on pediatric PPE/PE in Japan provides important insights into the clinical and bacteriologic features of the condition. The findings show a different trend in etiology compared to other countries and raise concerns about the underutilization of molecular methods for pathogenic diagnosis and the overuse of carbapenems. The establishment of clinical guidelines for PPE/PE in Japan is therefore imperative.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Article
Respiratory System
Minfang Li, Yunxiang Zeng, Yaqing Li, Dan Jia, Sheng Chen, Jinlin Wang
Summary: This study found that eosinophilic pleural effusion is mainly caused by malignant diseases, and should not be considered as a predictive factor of benign conditions. The presence of pleural parasitic infestation should be emphasized in areas with high incidence of parasitic diseases.
BMC PULMONARY MEDICINE
(2021)
Article
Health Care Sciences & Services
Oluwafemi Augustine Ajibola, Taiwo Opeyemi Aremu, Oluwatosin Esther Oluwole, Olawunmi Olayiwola, Nida Khokhar, Matthew Apedo, Valerie Cluzet
Summary: This case report presents a rare case of a 91-year-old Caucasian man with concurrent streptococci empyema and hepatic abscess. Interestingly, the hepatic abscess resolved after drainage of the empyema and initiation of antibiotics.
Article
Surgery
Andrew P. Dhanasopon, Justin D. Blasberg, Vincent J. Mase
Summary: Pneumothorax and pleural-based disease have a long history and consistent surgical goals. Pneumothorax requires pleural symphysis and prevention of recurrence, while the management of empyema depends on the patients' immune status, virulence of the organism, and timely treatment to achieve removal of infected fluid/tissue and lung reexpansion.
SURGICAL CLINICS OF NORTH AMERICA
(2022)
Article
Pediatrics
Matthieu Thimmesch, Andre Mulder, Frederic Lebrun, Frederic Pierart, Caroline Genin, Isabelle Loeckx, Pierre Demaret
Summary: This retrospective study examined the use of corticosteroids in the management of parapneumonic pleural effusion in children. The findings suggest that corticosteroids may be beneficial when conventional treatment fails, with a significant proportion of patients experiencing rapid resolution of fever after initiation of corticosteroid therapy. All patients were discharged from the hospital without the need for surgery.
PEDIATRIC PULMONOLOGY
(2022)
Meeting Abstract
Critical Care Medicine
Cordelia Solomon, Arthur Oliver Romero
Meeting Abstract
Critical Care Medicine
Hafiz Mahboob, Arthur Oliver Romero, Jacqueline Choa
Meeting Abstract
Critical Care Medicine
Arthur Romero, Nathaniel Ivanick, Mendy Lum, Ganesh Krishna
Article
Respiratory System
Bryan S. Benn, Arthur O. Romero, Mendy Lum, Ganesh Krishna
Summary: Robotic-assisted navigation bronchoscopy (RANB) combined with cone beam CT (CBCT) increases the sensitivity for malignancy and overall diagnostic accuracy of lung nodule biopsies, with a tissue diagnosis obtained in 83% of biopsied nodules, including 65% malignancies. Combining these modalities has the potential to shift the diagnostic approach to pulmonary nodules, with 85% sensitivity for malignancy and 86% diagnostic yield achieved.
Article
Respiratory System
Bryan S. Benn, Arthur Oliver Romero, Hasnain Bawaadam, Nathaniel Ivanick, Mendy Lum, Ganesh Krishna
Summary: This prospective study focused on assessing the use of CBCT guided TBLC with a novel articulating scope holder and prophylactic phenylephrine administration in patients with newly diagnosed DPLD. The results showed that this approach is safe, effective, and improves diagnostic accuracy, providing a potential alternative to surgical lung biopsy.
Meeting Abstract
Critical Care Medicine
Alfredo Iardino, Ipsita Samanta, Jill Ono, Arthur Oliver Romero
Meeting Abstract
Critical Care Medicine
Lance Horner, Geoffrey Douglas, Carmen Flores, Joseph Carroll, Arthur Oliver Romero
Meeting Abstract
Critical Care Medicine
Michael Pritchett, Barry Sigal, Mark Bowling, Melvin Morganroth, Michael Bernstein, Joseph Seaman, Joshiah Gordon, Archan Shah, Jonathan Kurman, Arthur Romero, Mostafa Tabassomi, Alejandro Aragaki, Donald Berry, Abhishek Biswas, Sandeep Bansal, Trevor Pitcher, Laura Peek, Steven Springmeyer
Letter
Respiratory System
Hasnain Bawaadam, Arthur O. Romero, Ganesh Krishna
JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
(2022)
Meeting Abstract
Critical Care Medicine
Rathnavali Katragadda, Chriselyn Palma, Arthur Oliver Romero
Meeting Abstract
Critical Care Medicine
Barry W. Sigal, Melvin L. Morganroth, Michael A. Bernstein, Mark R. Bowling, Archan Shah, Joseph C. Seaman, Jonathan S. Kurman, Joshiah R. Gordon, Arthur Oliver Romero, Alejandro Aragaki, Donald F. Berry, Sandeep Bansal, Abhishek Biswas, Michael A. Pritchett
Meeting Abstract
Critical Care Medicine
Jonathan S. Kurman, Barry W. Sigal, Mark R. Bowling, Melvin L. Morganroth, Michael A. Bernstein, Joseph C. Seaman, Joshiah R. Gordon, Archan Shah, Arthur Oliver Romero, Alejandro Aragaki, Donald F. Berry, Sandeep Bansal, Abhishek Biswas, Michael A. Pritchett
Meeting Abstract
Critical Care Medicine
Kushal D. Patel, Chriselyn Palma, Andrew Manfra, Arthur Oliver Romero
Meeting Abstract
Critical Care Medicine
M. Pritchett, B. W. Sigal, M. R. Bowling, M. L. Morganroth, M. A. Bernstein, A. Shah, J. Seaman, J. Gordon, A. Aragaki Nakahodo, A. O. Romero, J. S. Kurman, D. Berry
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2020)
Meeting Abstract
Critical Care Medicine
M. Azab, T. Al-Dawoodi, A. O. Romero, N. Vogelzang
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2018)
