Article
Rehabilitation
John R. Bach, Anam Purewal
Summary: Mechanical insufflation exsufflation can assist patients with respiratory issues in clearing pulmonary secretions, preventing lung infections, and also reducing headaches caused by coughing.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2021)
Article
Critical Care Medicine
Sung Eun Hyun, Sang-Min Lee, Hyung-Ik Shin
Summary: The study found that MI-E treatment via ETT generated slower PEF than via face mask, suggesting that a higher-pressure protocol should be prescribed for intubated patients to increase PEF speed.
Article
Respiratory System
John R. Bach, Won Ah Choi
Summary: Mechanical insufflation-exsufflation has shown significant benefits in reducing pneumonia rates and improving respiratory complications for patients with muscular dystrophy and spinal muscular atrophy. It has been successful in patients as young as 3 to 5 years old and can be used without resorting to tracheostomy in ventilator-unweanable patients. However, despite its effectiveness, noninvasive respiratory management is still underutilized.
Review
Medicine, General & Internal
B. Morrow, A. Argent, M. Zampoli, A. Human, L. Corten, M. Toussaint
Summary: Based on 11 studies involving 287 participants, the evidence suggests that cough augmentation techniques may increase peak cough flow compared to unassisted cough, but the certainty of the evidence is very low. The impact of these techniques on reducing respiratory infections and improving quality of life remains uncertain in more severe cases.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Respiratory System
J. R. Bach, A. W. Kazi, T. Pinto, M. R. Goncalves
Summary: The study suggests that ventilator unweanable morbidly obese patients can safely be extubated/decannulated and maintained indefinitely using continuous noninvasive ventilation (CNVS) without the need for resorting to tracheotomies.
Article
Critical Care Medicine
Anne-Fleur Haudebourg, Elsa Moncomble, Arnaud Lesimple, Flora Delamaire, Bruno Louis, Armand Mekontso Dessap, Alain Mercat, Jean-Christophe Richard, Francois Beloncle, Guillaume Carteaux
Summary: This study proposes a novel method for assessing airway opening pressure (AOP) during volume assist control ventilation at a constant-flow rate of 60 L/min. The P-cond method, which compares the airway pressure waveform to detect and measure AOP, was validated and showed good respiratory and hemodynamic tolerance compared to the standard low-flow method.
Article
Rehabilitation
John R. Bach, Hoa Pham
Summary: Many studies suggest that nasal noninvasive ventilation can provide a brief statistical benefit on survival and quality of life for patients with amyotrophic lateral sclerosis and other neuromuscular conditions. However, it is important to note that nasal noninvasive ventilation may not normalize CO2 levels and continuous positive airway pressure and O-2 exacerbate hypercapnia and often lead to CO2 narcosis, intubation, and ultimately tracheostomy or palliative care death. The use of continuous noninvasive ventilatory support with mechanical insufflation-exsufflation can be an effective alternative and even maintain patients without resort to tracheostomies.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2022)
Article
Critical Care Medicine
Jesus Sancho, Enric Bures, Santos Ferrer, Carolina Lahosa, Jaime Signes-Costa, Emilio Servera
Summary: This 2-year crossover study involving 19 ALS patients found that adding oscillations to MI-E therapy did not decrease the risk of respiratory infections, hospital admissions, or the need for bronchoscopy.
Article
Nursing
Willemke Stilma, Lotte Verweij, Bea Spek, Wilhelmina Johanna Maria Scholte Op Reimer, Marcus Josephus Schultz, Frederique Paulus, Louise Rose
Summary: This study explores the decision-making processes and barriers of healthcare professionals regarding the use of MI-E in invasively ventilated patients. The results indicate a lack of knowledge and expertise in using MI-E, highlighting the need for further research and development in this area.
NURSING IN CRITICAL CARE
(2023)
Article
Critical Care Medicine
Roberto Martinez-Alejos, Joan-Daniel Marti, Gianluigi Li Bassi, Daniel Gonzalez-Anton, Xabier Pilar-Diaz, Thomas Reginault, Philippe Wibart, George Ntoumenopoulos, Oystein Tronstad, Albert Gabarrus, Alice Quinart, Antoni Torres
Summary: Combining MI-E with ERCC increased sputum clearance, improved respiratory compliance, and enhanced oxygenation in mechanically ventilated subjects, without causing clinically significant hemodynamic changes or adverse events.
Review
Medicine, General & Internal
Jean-Paul Janssens, Chloe Cantero, Patrick Pasquina, Marjolaine Georges, Claudio Rabec
Summary: This article summarized the current knowledge in the field of monitoring during home ventilation and emphasized the effectiveness of long term noninvasive ventilation (LTNIV) for chronic hypercapnic respiratory failure (CHRF). By remotely adjusting ventilator settings and combining with other monitoring tools, patient comfort and tolerance can be improved, and hospital admissions can be reduced.
FRONTIERS IN MEDICINE
(2022)
Article
Respiratory System
Joan M. Teno, Donald R. Sullivan, Jen Bunker, Pedro Gozalo
Summary: In patients with advanced dementia hospitalized with pneumonia or septicemia with pneumonia, the use of invasive mechanical ventilation (IMV) compared to noninvasive ventilation (NIV) showed improved 30-day survival but did not provide a benefit in 1-year survival and had significantly higher healthcare costs.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2022)
Article
Multidisciplinary Sciences
Ewert Ralf, Alexander Heine, Anne Obst, Karoline Koerner, Veit Hustig-Kittler, Michael Boesche, Mohamed Elhadad, Beate Stubbe, Michael Westhoff
Summary: The establishment of guidelines for long-term noninvasive ventilation treatment in acute hypercapnic exacerbations of chronic obstructive pulmonary disease (AECOPD) has been elusive. Most studies have shown no mortality benefit of this treatment. However, our retrospective analysis of patient data from 2012 to 2019 demonstrated higher survival rates in the group receiving long-term noninvasive ventilation compared to those who didn't. This study provides evidence of the mortality benefit of long-term NIV therapy for AECOPD patients in real-world conditions.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Keiichi Funo, Yuri Negishi, Chika Akamine, Ryoko Takeuchi, Yoshihiro Uzawa
Summary: This study reports a case of using MI-E to treat an ALS patient. Due to the patient's short height, low BMI, and restricted lung capacity, the MI-E pressure was adjusted to prevent pneumothorax. The results showed that setting the pressure level lower than the manufacturer's recommendation was still effective in improving atelectasis without causing pneumothorax. This study suggests that using MI-E at lower pressures, along with treatment response observation, can reduce the risk of lung injury.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Anne Kristine Brekka, Maria Vollsaeter, George Ntoumenopoulos, Hege Havstad Clemm, Thomas Halvorsen, Ola Drange Roksund, Tiina Maarit Andersen
Summary: This study aims to evaluate if ultrasound imaging of the larynx can be used as an alternative less invasive diagnostic tool for evaluating the upper airway responses to non-invasive ventilation and mechanical insufflation-exsufflation.
Article
Critical Care Medicine
Daniel Martinez, Jesus Sancho, Emilio Servera, Julio Marin
Article
Rehabilitation
John R. Bach, Daniel Martinez, Bilal Saulat
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2010)
Letter
Respiratory System
Jose Franco, Daniel Martinez, Maria Meseguer
ARCHIVOS DE BRONCONEUMOLOGIA
(2011)
Article
Immunology
Daniel Martinez-Gonzalez, Jose Franco, David Navarro-Ortega, Carmen Munoz, Roberto Marti-Obiol, Rafael Borras-Salvador
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2011)
Article
Substance Abuse
Francisco Carrion Valero, Daniel Martinez Gonzalez, Ma Teresa Bobes-Bascaran, Genaro Galan Gil, Joaquin Ortega Serrano, Francisco Javier Chorro Gasco, Julio Bobes, Carlos A. Jimenez Ruiz
Summary: The objective of this study was to describe the characteristics of smokers admitted to different medical and surgical services in a university hospital and the perception of patients regarding the need for a specialized intervention. The findings showed that smokers had a high demand for tobacco treatment programs, with most of the sample having attempted to quit smoking. The study argues that the hospital context provides an opportunity to address smoking cessation.
Article
Respiratory System
Jesus Sancho, Daniel Martinez, Enric Bures, Jose Luis Diaz, Alejandro Ponz, Emilio Servera