Mesenchymal Stem Cells as Vectors for Lung Cancer Therapy

Optimizing patient derived mesenchymal stem cells as virus carriers for a Phase I clinical trial in ovarian cancer

(2013) Emily K Mader et al.   Journal of Translational Medicine

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

(2012) Ronne Wee Yeh Yeo et al.   ADVANCED DRUG DELIVERY REVIEWS

In vitro anti-myeloma activity of TRAIL-expressing adipose-derived mesenchymal stem cells

(2012) Sabino Ciavarella et al.   BRITISH JOURNAL OF HAEMATOLOGY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Silica Nanorattle–Doxorubicin-Anchored Mesenchymal Stem Cells for Tumor-Tropic Therapy

(2011) Linlin Li et al.   ACS Nano

Combination of vorinostat and adenovirus-TRAIL exhibits a synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells

(2011) D R Kim et al.   CANCER GENE THERAPY

Activation of autophagy in mesenchymal stem cells provides tumor stromal support

(2011) Cecilia G. Sanchez et al.   CARCINOGENESIS

Death Receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells

(2011) Ling Su et al.   EUROPEAN JOURNAL OF CANCER

Human adipose tissue-derived mesenchymal stem cells: Characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas

(2011) Seung Ah Choi et al.   EUROPEAN JOURNAL OF CANCER

Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo

(2010) Wanjing Ding et al.   CANCER LETTERS

TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors

(2010) D. Stadel et al.   CLINICAL CANCER RESEARCH

Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment

(2010) Shannon Kidd et al.   CYTOTHERAPY

RNAi-Mediated Inhibition of XIAP Combined with Systemic Mesenchymal Stem Cell-mediated Delivery of STRAIL Inhibits Metastatic Growth of Pancreatic Carcinoma Cells

(2010) S.M. Albarenque et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL

(2010) Alena Vaculova et al.   Molecular Cancer

Targeting of XIAP Combined with Systemic Mesenchymal Stem Cell-Mediated Delivery of sTRAIL Ligand Inhibits Metastatic Growth of Pancreatic Carcinoma Cells

(2010) Andrea Mohr et al.   STEM CELLS

Therapeutic potential of human mesenchymal stem cells producing IL-12 in a mouse xenograft model of renal cell carcinoma

(2009) Peng Gao et al.   CANCER LETTERS

Magnetic Resonance Imaging of Mesenchymal Stem Cells Homing to Pulmonary Metastases Using Biocompatible Magnetic Nanoparticles

(2009) M. R. Loebinger et al.   CANCER RESEARCH

Mesenchymal Stem Cell Delivery of TRAIL Can Eliminate Metastatic Cancer

(2009) M. R. Loebinger et al.   CANCER RESEARCH

Therapeutic potential of mesenchymal stromal cells in a mouse breast cancer metastasis model

(2009) Bo Sun et al.   CYTOTHERAPY

Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy

(2009) Ryosuke Uchibori et al.   JOURNAL OF GENE MEDICINE

Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation

(2009) Catherine Gill et al.   Molecular Cancer

Mapatumumab and lexatumumab induce apoptosis in TRAIL-R1 and TRAIL-R2 antibody-resistant NSCLC cell lines when treated in combination with bortezomib

(2009) T. A. Luster et al.   MOLECULAR CANCER THERAPEUTICS

Human Bone Marrow-Derived Mesenchymal Stromal Cells Expressing S-TRAIL as a Cellular Delivery Vehicle for Human Glioma Therapy

(2009) Lata G. Menon et al.   STEM CELLS

NF-κB downregulation may be involved the depression of tumor cell proliferation mediated by human mesenchymal stem cells

(2008) Ling QIAO et al.   ACTA PHARMACOLOGICA SINICA

Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway

(2008) S Shamimi-Noori et al.   CANCER GENE THERAPY

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

(2008) Devalingam Mahalingam et al.   CANCER TREATMENT REVIEWS

Cardiac regeneration and stem cell therapy

(2008) Joshua M Hare et al.   Current Opinion in Organ Transplantation

Cancer gene therapy using mesenchymal stem cells expressing interferon-β in a mouse prostate cancer lung metastasis model

(2008) C Ren et al.   GENE THERAPY

Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice

(2008) Lucia Kucerova et al.   JOURNAL OF GENE MEDICINE

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs

(2008) Xiancheng Chen et al.   MOLECULAR THERAPY

Targeted Migration of Mesenchymal Stem Cells Modified With CXCR4 Gene to Infarcted Myocardium Improves Cardiac Performance

(2008) Zhaokang Cheng et al.   MOLECULAR THERAPY

Stem cells and cell therapies for cystic fibrosis and other lung diseases

(2008) Daniel J. Weiss   PULMONARY PHARMACOLOGY & THERAPEUTICS