Journal
RESEARCH ON CHEMICAL INTERMEDIATES
Volume 41, Issue 8, Pages 5907-5914Publisher
SPRINGER
DOI: 10.1007/s11164-014-1710-x
Keywords
Lactose; Tetrahydrobenzo[b]pyran; Malononitrile; Dimedone
Categories
Funding
- University of Sistan
- Baluchestan Research Council
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Lactose has been used as a mild, efficient, green, and inexpensive catalyst for the synthesis of tetrahydrobenzo[b]pyran derivatives via a one-pot, three-component condensation between aryl aldehydes, malononitrile, and dimedone in H2O:EtOH at 60 A degrees C. This method offers a considerable number of advantages including short reaction time, high to quantitative yields, low cost, easy accesses, and simple work-up.
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