Article
Biochemistry & Molecular Biology
Jonghwa Lee, Kyeonga Kim, Jemin Son, Hyeseon Lee, Jin Han Song, Taek Lee, Heungbae Jeon, Hyun Soo Kim, Si Jae Park, Hah Young Yoo, Chulhwan Park
Summary: In this study, naringin oleate was synthesized through enzymatic esterification with optimized reaction conditions, resulting in a high conversion rate. This study presents an efficient method for synthesis that ensures high conversion within a shorter reaction time compared to previous methods.
Review
Pharmacology & Pharmacy
Zahra Memariani, Syed Qamar Abbas, Syed Shams Ul Hassan, Amirhossein Ahmadi, Aroona Chabra
Summary: Cancer rates are increasing in many low- and middle-income countries due to various factors, including lifestyle changes and societal problems. Different treatment approaches like chemotherapy, surgery, and radiation therapy are used, but can have various short- and long-term side effects. Recent studies show that compounds like naringin and naringenin from citrus fruits have anti-cancer properties through different signaling pathways, and when combined with current anti-cancer agents, can show synergistic effects and help overcome multidrug resistance in cancer treatment.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Environmental Sciences
Yesol Baek, Seungmee Lee, Jemin Son, Taek Lee, Jong-Min Oh, Sang Hun Lee, Hyun Uk Kim, Sang Woo Seo, Si Jae Park, Hah Young Yoo, Chulhwan Park
Summary: Naringin, a natural antioxidant found in citrus flavonoids, has limited bioavailability due to its low stability and solubility. However, recent reports have shown that acylation can improve the physical and chemical properties of naringin esters. This study aimed to enhance the conversion of naringin acetate using enzymatic reactions. By optimizing various factors, such as enzyme type, concentration, acyl donor, reaction temperature, and solvent, a high conversion rate of naringin acetate was achieved within a short time, demonstrating the commercial potential of this process.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Biochemistry & Molecular Biology
V. S. Shilpa, Rafeeya Shams, Kshirod Kumar Dash, Vinay Kumar Pandey, Aamir Hussain Dar, Shaikh Ayaz Mukarram, Endre Harsanyi, Bela Kovacs
Summary: This review discussed the innovative approaches for naringin extraction and the recent developments in the field. It evaluated naringin in terms of its structure, composition, and food sources, as well as its pharmacological properties. Naringin is a crucial flavonoid with various biological and medicinal effects.
Article
Nutrition & Dietetics
Xuan Zeng, Yuying Zheng, Yan He, Jiashuo Zhang, Wei Peng, Weiwei Su
Summary: This study investigated the microbial metabolism of naringin in laboratory rats using an in vitro anaerobic fermentation method. A total of 35 microbial metabolites were identified, and corresponding metabolic pathways were proposed. The study also found that the microbial metabolites of naringin exhibited higher antioxidant activity than the original compound.
Article
Agriculture, Dairy & Animal Science
Kazeem D. Adeyemi, Oluwaseun O. Oludemokun, Marili F. Zubair, Olubunmi Atolani, Sulyman O. Ibrahim
Summary: This study investigated the effects of dietary supplementation of Plukenetia conophora seed (PCS) on the growth performance, blood chemistry, hepatic antioxidant status, fillet fatty acids, and physicochemical properties of Clarias gariepinus. The results showed that including PCS in the diet increased the growth rate and specific growth rate of C. gariepinus, while also improving the antioxidant status and fatty acid composition of the fish fillet.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
Tasmina Kanwal, Khadija Rehman, Huzaifa Muhammad Hamid, Ali Asgher Shuja, Salim Saifullah, Tauseef Ahmed, Muhammad Hasnain, Shabana Usman Simjee, Muhammad Raza Shah
Summary: A self-nanoemulsifying drug delivery system containing alkylated arginine was developed to enhance the anticancer and antioxidant activities of naringin. The developed system was stable and did not alter the chemical nature of the drug. The incorporation of alkylated arginine greatly improved the antioxidant and anticancer properties of naringin.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Review
Oncology
Lili Cao, Jiawei Wang, Yujuan Zhang, Feng Tian, Chunfang Wang
Summary: Traditional herbal flavonoids can be used as alternative drugs to prevent and treat osteoporosis. Compounds like quercetin and icariin promote bone formation and have been widely studied over the past five years.
MOLECULAR MEDICINE REPORTS
(2022)
Article
Plant Sciences
Jiaoke Zeng, Chuying Chen, Ming Chen, Jinyin Chen
Summary: Naringin treatment delays citrus fruit decay and maintains fruit quality by promoting metabolite accumulation and upregulating differentially expressed genes in the phenylpropanoid and flavonoid biosynthesis pathways.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Fouad Ali Abdullah Abdullah, Michaela Trnkova, Dani Dordevic
Summary: Consumer interest in health, food quality, and environmental issues has increased. This study evaluates the impact of different rearing systems on pork meat's physicochemical properties and oxidation states.
APPLIED SCIENCES-BASEL
(2023)
Article
Oncology
Eman E. Mohamed, Osama M. Ahmed, Khairy M. A. Zoheir, Ahmed A. G. El-Shahawy, Shadi Tamur, Anwar Shams, Jack T. Burcher, Anupam Bishayee, Adel Abdel-Moneim
Summary: Despite advancements in the field, lung malignancies are still the primary cause of cancer-attributable morbidity and mortality globally. This study found that naringin-dextrin nanocomposites (Nar-Dx-NCs) improved the preventive action of naringin against lung cancer by suppressing oxidative stress, inflammation, and cell proliferation, and activating apoptosis.
Article
Food Science & Technology
Huifan Liu, Churong Liang, Lukai Ma, Jianliang Liu, Qin Wang
Summary: The study found that external injuries in fruitlets can trigger the synthesis of naringin to cope with stress, and lead to an increased activity of antioxidant enzymes.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Chemical
Debao Niu, Er -Fang Ren, Jian Li, Xin-An Zeng, Si -Lun Li
Summary: Pulsed electric field (PEF) treatment significantly improves the extraction yield of naringin from pomelo peel, with specific effects observed at an electric field intensity of 4 kV/cm and 30 pulses. Different PEF treatments impact the antioxidant activity of naringin, possibly due to changes in its structure. PEFF treatment alters the conformation of naringin without degradation, showing promise for enhancing extraction efficiency and modifying physicochemical properties in the future.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Syed Sarim Imam, Sadaf Jamal Gilani, Ameeduzzafar Zafar, May Nasser bin Jumah, Raisuddin Ali, Mohammed Muqtader Ahmed, Sultan Alshehri
Summary: The study aimed to prepare and optimize Naringin hybrid nanoparticles, showing improved drug release, enhanced permeation, increased antimicrobial activity, and better activity in tested cell lines.
Article
Biochemistry & Molecular Biology
Shanoo Suroowan, E. J. Llorent-Martinez, Gokhan Zengin, Asaad Khalid, Ashraf N. Abdalla, Soud Khogeer, Bao Van, Mohamad Fawzi Mahomoodally
Summary: This study investigated the phytochemical and pharmacological properties of Wikstroemia indica. The methanolic extract showed the highest content of phenolic compounds and exhibited the strongest antioxidant potential. The ethyl acetate extract and methanolic extract demonstrated good inhibitory activity against acetylcholinesterase, and the ethyl acetate extract also showed activity against butyrylcholinesterase. The tyrosinase and alpha amylase inhibitory potentials were confirmed, and the aqueous extract showed cytotoxicity against HT 29 cells.
PROCESS BIOCHEMISTRY
(2023)
Article
Physiology
Alba Martin, F. Javier Giraldez, Paola Cremonesi, Bianca Castiglioni, Filippo Biscarini, Fabrizio Ceciliani, Nuria Santos, Sonia Andres
Summary: This study found that adding L-Carnitine to the diet during the fattening period of lambs fed with restricted feed can improve ruminal fermentation parameters, modulate gut microbiota, and enhance the health of the animals. However, the effects of L-Carnitine on feed efficiency were not significant, possibly due to the improved ruminal fermentation and increased intramuscular fat accumulation caused by L-Carnitine supplementation.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Agronomy
Egon Henrique Horst, Hajer Ammar, Rawiya Ben Rhouma, Mariem Khouja, Mohamed Larbi Khouja, Francisco Javier Giraldez, Secundino Lopez
Summary: This study evaluated the nutritional value of eucalyptus leaves from five different species harvested in Tunisia. The results showed that eucalyptus foliage has limited energy and protein value as an alternative fodder for ruminants, with variations across species but no remarkable seasonal changes.
AGROFORESTRY SYSTEMS
(2022)
Article
Agriculture, Dairy & Animal Science
Alba Martin, F. Javier Giraldez, Olimpio Montero, Sonia Andres
Summary: Early feed restricted lambs can benefit from supplementation of L-carnitine, which improves muscle/heart function by increasing the expression of genes related to ribosomes or cholesterol excretion.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Mariem BenJemaa, Fatma Zohra Rahali, Hanen Falleh, Raja Beji-Serairi, Wided Megdiche-Ksouri, Ibtissem Hamrouni, Majdi Hammami, Ralph Nehme, Renato B. Pereira, Sonia Andres, Said Bouhallab, David M. Pereira, Fabrizio Ceciliani, Latifa Abdennebi-Najar, Riadh Ksouri
Summary: This study aimed to optimize the encapsulation of Thymus capitatus essential oil into nanoemulsion. The results showed that the encapsulated nanoemulsion exhibited improved stability, antimicrobial efficacy, and sensory appreciation in enriched milk.
Article
Multidisciplinary Sciences
Veronica Castilla Gomez de Aguero, Cristina Esteban-Blanco, Hector Arguello, Elora Valderas-Garcia, Sonia Andres, Rafael Balana-Fouce, Juan Jose Arranz, Beatriz Gutierrez-Gil, Maria Martinez-Valladares
Summary: Gastrointestinal nematodes (GIN) pose a major threat to the health and welfare of small ruminants worldwide. This study found that the composition of the microbiome may be associated with the resistance of sheep to infection by GIN.
SCIENTIFIC REPORTS
(2022)
Article
Agriculture, Dairy & Animal Science
Raul Bodas, F. Javier Giraldez, Sara Olmedo, Marta Herrera, Susana Loran, Agustin Arino, Secundino Lopez, Alberto Benito, Teresa Juan
Summary: This study investigated the transfer of aflatoxin B1 (AFB1) to Assaf ewes' milk and its effect on animal performance and health. The results showed that AFB1 was converted to aflatoxin M1 (AFM1) and the conversion rate depended on the dose of AFB1 and milk yield. There was no significant effect on milk yield and health of the ewes.
Article
Agriculture, Dairy & Animal Science
Javier Mateo, Irma Caro, Sergio Soto, Sonia Andres, Rocio Alaiz-Rodriguez, Emma Serrano
Summary: Grass silage has an effect on beef quality, increasing saturated fatty acids, n-3 fatty acids, and beta-carotene while decreasing monounsaturated and polyunsaturated fatty acids. Beef from silage-fed bulls and straw-fed bulls can be differentiated by fatty acid percentages, beta-carotene content, b* colour value, and carotenoid colour index. The feeding of grass silage also affects the perirenal fat composition.
Article
Agronomy
Egon Henrique Horst, Hajer Ammar, Mohamed Larbi Khouja, Julio Ernesto Vargas, Sonia Andres, Secundino Lopez
Summary: This study assessed the effects of different eucalyptus species harvested in different seasons on in vitro rumen fermentation and methane production. The results showed that the foliage of E. sideroxylon and E. lehmannii had the highest digestibility and were most effective at reducing methane emission. Foliage harvested in winter had higher digestibility and increased acetate-to-propionate ratio without increasing methane emission. Foliage from E. sideroxylon and E. lehmannii showed potential to decrease enteric methane production without affecting ruminal fermentation.
Article
Food Science & Technology
A. Martin, F. J. Giraldez, J. Mateo, I. Caro, S. Andres
Summary: Early feed restriction leads to permanent mitochondrial dysfunction in lambs, which impairs fatty acid oxidation. Dietary L-carnitine can improve mitochondrial function and modify lipid metabolism and meat quality traits in these lambs. However, it also negatively affects the fatty acid profile.
Article
Multidisciplinary Sciences
Maria Jose Ranilla, Sonia Andres, Chiara Gini, Filippo Biscarini, Cristina Saro, Alba Martin, Ivan Mateos, Secundino Lopez, F. Javier Giraldez, Latifa Abdennebi-Najar, David Pereira, Hanen Falleh, Riadh Ksouri, Paola Cremonesi, Bianca Castiglioni, Fabrizio Ceciliani
Summary: An in vitro trial was conducted to study the effects of natural Thymbra capitata essential oil and its main compounds on ruminal fermentation and the bacterial community. The results showed that the essential oil reduced the total volatile fatty acids, while methane production was not affected.
SCIENTIFIC REPORTS
(2023)
Article
Biotechnology & Applied Microbiology
Julio Ernesto Vargas, Lorena Lopez-Ferreras, Sonia Andres, Ivan Mateos, Egon Henrique Horst, Secundino Lopez
Summary: The purpose of this study was to differentiate the effects of diet composition and ruminal pH on fermentation patterns and microbial profiles in a continuous culture system. The results showed that high concentrate diets were more digestible and resulted in greater fermentation end-products and microbial protein production. A decline in rumen pH decreased feed digestibility and the daily outputs of some fermentation end-products, but had no effect on microbial protein synthesis.
FERMENTATION-BASEL
(2023)
Article
Veterinary Sciences
R. Mischke, K. Rumstedt, S. O. Hungerbuehler, K. Rohn, M. Schmicke
Summary: Contrast-enhanced ultrasound (CEUS) can provide an additional tool for the diagnosis of hypothyroidism in dogs and support its differentiation from non-thyroidal illness. Sedation has limited impact on CEUS results.
RESEARCH IN VETERINARY SCIENCE
(2024)
Review
Veterinary Sciences
Lucas Petitemberte de Souza, William Borges Domingues, Eduardo Bierhals Blodorn, Leandro da Silva Nunes, Hadassa Gabriela Ortiz, Eliza Rossi Komninou, Vinicius Farias Campos
Summary: This study performed a systematic review of the differential expression of sperm microRNAs in bulls related to fertility. A total of 182 unique differentially expressed miRNAs were identified, among which 49 miRNAs were found in common between at least two studies. The results suggest that miRNAs such as miR-10a, -10b, -103, -15b, -122, -125b, -126-5p, -151-5p, -193a-5p, -196a, -27a-5p, and -99b may serve as potential universal biomarkers for assessing the reproductive potential of males.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Wonhee Cha, Katinca Fungbrant, Giulio Grandi, Ylva Persson
Summary: This study investigated the prevalence and development of hair loss in outdoor cattle in Sweden. It found a relatively high hair loss rate, with the occurrence of hair loss increasing over time during winters, suggesting a contagious etiology. The study also identified preventative delousing before November, keeping animals clean, and maintaining small group sizes as effective measures to reduce the risk of hair loss, while older age and access to bedding materials increased the risk.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Sheeba Thomas, David Francis Lappin, David Bennett, Christopher Nile, Marcello Pasquale Riggio
Summary: This study found that Feline odontoclastic resorptive lesion (FORL) can be divided into two subgroups, with FORL-1 subgroup having a less diverse oral microbiome and higher levels of proinflammatory cytokines and chemokines, which may be associated with the severity and activity of the disease.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
S. L. Gayathri, M. Bhakat, T. K. Mohanty
Summary: This study used infrared thermography (IRT) to identify mastitis in Sahiwal cows. The results showed significant differences in the mean values of udder and teat surface temperature between healthy, subclinical mastitis (SCM), and clinical mastitis (CM) cases during different seasons. IRT is an efficient tool for the early identification of subclinical mastitis.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Zeynep Ozdemir Kutahya, Busra Aslan Akyol, Kubra Deliklitas, Cengiz Gokbulut
Summary: In this study, the pharmacokinetic behavior of Eprinomectin was studied in two different goat breeds. The results showed no significant differences in plasma concentration between the breeds, but the clearance from the body may vary. High concentration of Eprinomectin in feces is beneficial against gastrointestinal parasites but poses an ecotoxicological risk to the environment.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Mohammad Ashrafzadeh-Shiraz, Mousa Tavassoli, Bahram Dalir-Naghadeh, Alireza Sazmand
Summary: This study evaluated the efficacy of fenbendazole and ivermectin on strongyles and Parascaris sp. infecting adult riding horses in different regions of Iran. The results demonstrated varying degrees of resistance of these parasites to both anthelminthics. It emphasizes the urgency of educating horse owners about the importance of a test-and-treatment strategy and suggests evaluating the efficacy of different anthelminthics to choose the most effective treatment in each region.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Moises Gonzalvez, Clara Munoz-Hernandez
Summary: The study evaluated the use of R software in research articles addressing the study of wildlife, showing an increasing trend in the number of publications over time and a wide geographical distribution globally.
RESEARCH IN VETERINARY SCIENCE
(2024)
