4.3 Review

Theoretical methods for identifying important functional genes in bacterial genomes

Journal

RESEARCH IN MICROBIOLOGY
Volume 161, Issue 1, Pages 1-8

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.resmic.2009.10.007

Keywords

Hypothetical genes; Essential genes (EGs); Highly expressed genes (HEGs); Horizontally transferred genes (HTGs); Pathogenic bacteria

Categories

Funding

  1. National High Technology Research and Development Program of China [2008AA09Z411]
  2. National Natural Science Foundation of China [30600119]

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Some functional genes, such as essential genes, highly expressed genes and horizontally transferred genes, play important roles in the survival and pathogenicity of bacteria. This review attempts to summarize current computational methods in identifying the above functional genes from bacterial genomes, which is of significant importance in exploring the bacterial genomes. (C) 2009 Elsevier Masson SAS. All rights reserved.

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