Article
Integrative & Complementary Medicine
Bing Qu, Yunhe Xiong, Xiaofan Yu, Jinli Ding, Jing Weng, Xinghua Yang, Yanmin Ma, Lingyan Liu, Jing Yang
Summary: The outcomes of IVF/ICSI are affected by follicular metabolites and physical status in couples, with different mechanisms in tube and sperm abnormalities groups, and male and female factors play crucial roles in IVF/ICSI results.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2021)
Article
Obstetrics & Gynecology
Jingjuan Ji, Xinyi Zhu, Yan Zhang, Lijun Shui, Shun Bai, Lingli Huang, Haoyu Wang, Shiwei Fan, Zelin Zhang, Lihua Luo, Bo Xu
Summary: Embryo selection is crucial in IVF, and morphological assessment is commonly used but sometimes inaccurate. Analyzing proteomic profiles of human follicular fluid (FF) and identifying predictive biomarkers can be helpful in evaluating embryo quality.
REPRODUCTIVE SCIENCES
(2023)
Article
Biology
Ju Wang, Wei Zheng, Shuoping Zhang, Keqiang Yan, Miao Jin, Huiling Hu, Zhen Ma, Fei Gong, Guangxiu Lu, Yan Ren, Liang Lin, Ge Lin, Liang Hu, Siqi Liu
Summary: This study established a model for evaluating embryo or oocyte quality based on metabolites in follicular fluid, with phosphatidylcholines identified as key contributors. The increase of PCs in follicular fluid may lead to a decrease in embryo quality. Pathway analysis suggested that accumulation of arachidonic acid induced by PCs could weaken embryo quality.
Article
Biochemistry & Molecular Biology
Rubi Rodriguez-Diaz, Raquel Blanes-Zamora, Soraya Paz-Montelongo, Jorge Gomez-Rodriguez, Sonsoles Rodriguez Fiestas, Dailos Gonzalez-Weller, Angel J. Gutierrez, Carmen Rubio, Arturo Hardisson, Daniel Niebla-Canelo, Samuel Alejandro Vega, Enrique Gonzalez-Davila
Summary: Infertility has become more common due to increased exposure to toxic compounds, including heavy metals. The levels of 22 metals in the follicular fluid of 93 females were measured, and their impact on assisted reproduction technique (ART) was examined. Low levels of copper, zinc, aluminium, and calcium were found to be associated with polycystic ovary syndrome. There were significant relationships between the number of oocytes and iron and calcium levels, as well as between the number of mature oocytes and iron, calcium, and sodium levels.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Reproductive Biology
Nima Azari-Dolatabad, Annelies Raes, Krishna Chaitanya Pavani, Anise Asaadi, Daniel Angel-Velez, Petra Van Damme, Jo L. M. R. Leroy, Ann Van Soom, Osvaldo Bogado Pascottini
Summary: The study evaluated the effect of adding different concentrations of bovine follicular fluid on oocyte maturation and blastocyst quality, showing that supplementation of 5% FF improved cumulus expansion and blastocyst development and quality in an individual culture system.
Article
Genetics & Heredity
Yue Liu, Zhiheng Yu, Shigang Zhao, Lei Cheng, Yuanyuan Man, Xueying Gao, Han Zhao
Summary: Elevated oxidative stress levels were found in both the serum and follicular fluid of PCOS patients compared to normal controls, with the former showing more severe oxidative stress. The study revealed that oxidative stress in follicular fluid has a stronger impact on embryo quality, highlighting the importance of this factor in future research.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2021)
Article
Environmental Sciences
Richelle D. Bjorvang, Ida Hallberg, Anne Pikki, Lars Berglund, Matteo Pedrelli, Hannu Kiviranta, Panu Rantakokko, Paivi Ruokojarvi, Christian H. Lindh, Matts Olovsson, Sara Persson, Jan Holte, Ylva Sjunnesson, Pauliina Damdimopoulou
Summary: This study examines the impact of persistent organic pollutants (POPs) on reproductive health and finds that age plays a crucial role in the transfer of chemicals from blood to follicular fluid. Moreover, exposure to POPs is significantly associated with assisted reproductive technology (ART) outcomes.
ENVIRONMENTAL RESEARCH
(2022)
Article
Cell Biology
Florentin-Daniel Staicu, Analuce Canha-Gouveia, Cristina Soriano-Ubeda, Juan Carlos Martinez-Soto, Evdochia Adoamnei, Jorge E. Chavarro, Carmen Matas
Summary: The levels of nitrite and nitrate in follicular fluid were found to be related to the yield of MII oocytes, and nitrate levels showed a suggestive inverse correlation with embryos with high potential of implantation. This suggests that nitrite and nitrate concentrations in follicular fluid may be useful in predicting ovarian response and embryo implantation potential.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Obstetrics & Gynecology
Martin Stimpfel, Nina Jancar, Eda Vrtacnik-Bokal
Summary: Collecting semen samples at home has a positive effect on sperm quality, but no significant differences in cycle outcomes are observed when these samples are used in IVF/ICSI cycles.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Reproductive Biology
Tzung-En Tsai, Pei-Hsuan Lin, Pei-Fen Lian, Chia-Jung Li, Salvatore Giovanni Vitale, Mislav Mikus, Wan-Ping Su, Hsiao-Wen Tsai, Kuan-Hao Tsui, Li-Te Lin
Summary: AOA may improve embryo quality in older patients with diminished ovarian reserve undergoing IVF-ICSI cycles, especially in women aged >= 40 years old.
JOURNAL OF OVARIAN RESEARCH
(2022)
Article
Endocrinology & Metabolism
Yaoxuan Li, Shikai Wang, Dawen Li, Yueyue Huang, Haifang Liu, Xiaohui Zhang, Jie Qin, Xianbao Mao, Zhengda Li, Liangshi Chen, Pingpin Wei, Wen Shi, Lintao Xue
Summary: The study found that short-interval second ejaculation on the day of oocyte retrieval can significantly improve sperm quality and embryo development in oligoasthenozoospermic males receiving intracytoplasmic sperm injection (ICSI) treatment, suggesting a non-invasive and effective strategy for improving ICSI outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Ana Raquel Neves, Samuel Santos-Ribeiro, Sandra Garcia-Martinez, Marta Devesa, Sergio R. Soares, Juan Antonio Garcia-Velasco, Nicolas Garrido, Nikolaos P. Polyzos
Summary: The study found that in a freeze-all approach, there was no significant difference in euploidy rate and cumulative live birth rate between PGT-A cycles with and without late-follicular progesterone elevation.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Reproductive Biology
Ana P. Flores Bragulat, Isabel Ortiz, Jaime Catalan, Jesus Dorado, Manuel Hidalgo, Luis Losinno, Marta Dordas-Perpinya, Ivan Yanez-Ortiz, Iris Martinez-Rodero, Jordi Miro, Andres Gambini
Summary: This study investigated the effect of supplementation with jenny preovulatory follicular fluid (PFF) on oocyte developmental competence in donkeys. The results showed that IVM media supplemented with FBS or donkey PFF can promote nuclear maturation and early embryo development in donkeys. This study is the first report of ICSI, time-lapse imaging, and in vitro blastocyst production in donkeys.
Article
Genetics & Heredity
Haroon Latif Khan, Shahzad Bhatti, Sana Abbas, Celal Kaloglu, Syeda Qurat-ul-Ain Zahra, Yousaf Latif Khan, Zahira Hassan, Nilgun Ozturk Turhan, Hikmet Hakan Aydin
Summary: The study found that patients with low melatonin levels in follicular fluid had significantly higher oxidative stress markers, cfDNA levels, and lower relative expression of certain miRNAs compared to other groups. These patients also had lower fertilization rates and fewer high-quality day 3 embryos.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2021)
Article
Obstetrics & Gynecology
Liese Boudry, Wafaa Essahib, Ileana Mateizel, Hilde Van de Velde, Deborah De Geyter, Denis Pierard, Wim Waelput, Valerie Uvin, Herman Tournaye, Michel De Vos, Michael De Brucker
Summary: This study investigated the presence of viral RNA in the follicular fluid, cumulus cells, and endometrial tissue samples of SARS-CoV-2-positive women undergoing assisted reproductive technology (ART). The results showed that viral RNA was undetectable in these samples.
FERTILITY AND STERILITY
(2022)
Article
Cell Biology
Gil Kamergorodsky, Adriana L. Invitti, Paulo D'Amora, Rafael M. Parreira, Alexander Kopelman, Tatiana C. S. Bonetti, Manoel J. B. C. Girao, Eduardo Schor
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2020)
Article
Medicine, General & Internal
Nayara Moya Rios do Vale, Flavia Roche Moreira Latini, Carine Prisco Arnoni, Rafael Martins Parreira, Manoel Joao Batista Castelo Girao, Afonso Jose Pereira Cortez, Tatiana Carvalho de Souza Bonetti
Summary: This study evaluated the seroprevalence of COVID-19 antibodies in blood donors from a blood bank in Sao Paulo, Brazil. The results showed an increasing trend of seroprevalence over time, with variations among different regions and socio-demographic factors.
Article
Immunology
M. Veronica Lopez, Sabrina E. Vinzon, Eduardo G. A. Cafferata, Felipe J. Nunez, Ariadna Soto, Maximiliano Sanchez-Lamas, M. Jimena Afonso, Diana Aguilar-Cortes, Gregorio D. Rios, Juliana T. Maricato, Carla T. Braconi, Vanessa B. Silveira, Tatiane M. Andrad, Tatiana C. S. Bonetti, Luiz M. Ramos Janini, Manoel J. B. C. Girao, Andrea S. Llera, Karina A. Gomez, Hugo H. Ortega, Paula M. Berguer, Osvaldo L. Podhajcer
Summary: A novel vaccine based on a chimeric human adenovirus 5 vector was developed, which induced potent humoral and T-cell immunity lasting at least 5 months by enhancing Spike expression, infection of muscle and dendritic cells, and utilizing stabilized Spike in a prefusion conformation. Vaccinated mice showed neutralizing antibodies against various Spike variants and maintained stable immunity for over 5 months, suggesting potential for clinical trials.
Article
Obstetrics & Gynecology
Pedro Felipe Magalhaes Peregrino, Tatiana Carvalho de Souza Bonetti, Alecsandra Prado Gomes, Hamilton de Martin, Jose Maria Soares Junior, Edmund Chada Baracat, Pedro Augusto Araujo Monteleone
Summary: This study aimed to evaluate the effectiveness of transferring two sequential SET procedures compared with a double embryo transfer (DET) in freeze-only cycles.
REVISTA BRASILEIRA DE GINECOLOGIA E OBSTETRICIA
(2022)
Letter
Andrology
Pedro Augusto Araujo Monteleone, Tatiana Carvalho de Souza Bonetti
SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE
(2023)
Article
Medicine, General & Internal
Franco Loeb Chazan, Tatiana C. S. Bonetti, Mariano Tamura Vieira Gomes, Vinicius Adami Vayego Fornazari, Manoel Joao Batista Castello Girao, Claudio Emilio Bonduki
Summary: The study found that the expression of MMP3 significantly decreased after uterine artery embolization, while the expression of MMP10 did not show significant changes, indicating that AEM has an impact on ECM for at least 6 months after the procedure.
Meeting Abstract
Obstetrics & Gynecology
H. De Martin, G. Alecsandra, M. Fujii, M. Conatti, M. Nakano, T. Bonetti, P. Monteleone
HUMAN REPRODUCTION
(2020)
Meeting Abstract
Obstetrics & Gynecology
P. A. Monteleone, P. Peregrino, J. Miorin, A. Gomes, H. Martin, T. Bonetti
HUMAN REPRODUCTION
(2020)
Meeting Abstract
Obstetrics & Gynecology
A. Gomes, H. De Martin, M. Fujji, M. Conatti, M. Nakano, T. Bonetti, P. Monteleone
HUMAN REPRODUCTION
(2020)
Article
Obstetrics & Gynecology
Luciene K. Tsukuda, Aline R. Lorenzon, Tatiana C. S. Bonetti, Paulo Cesar Serafini, Eduardo L. A. Motta, Ricardo M. A. Pereira, Thais Sanches Domingues
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2020)
Article
Obstetrics & Gynecology
Mauricio B. Chehin, Renato Fraietta, Aline R. Lorenzon, Tatiana C. S. Bonetti, Eduardo L. A. Motta
THERAPEUTIC ADVANCES IN REPRODUCTIVE HEALTH
(2020)
Review
Obstetrics & Gynecology
Pedro A. A. Monteleone, Mayra Nakano, Victor Lazar, Alecsandra P. Gomes, Hamilton de Martin, Tatiana C. S. Bonetti
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2020)
Article
Obstetrics & Gynecology
Tatiana C. S. Bonetti, Debora C. M. Haddad, Thais S. Donningues, Jose Roberto Alegretti, Eduardo L. A. Motta, Kent Seeley, Ismael D. C. G. Silva
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2019)
Article
Obstetrics & Gynecology
Thais S. Domingues, Tatiana C. S. Bonetti, Daniel C. Pimenta, Douglas O. C. Mariano, Bruna Barros, Ana Paula Aquino, Eduardo L. A. Motta
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2019)
Article
Obstetrics & Gynecology
Pedro F. M. Peregrino, Alecsandra Gomes, Mariana Fujii, Tatiana C. S. Bonetti, Marcia Riboldi, Pedro A. A. Monteleone
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2019)
Article
Obstetrics & Gynecology
Alice Newman-Sanders, Jackson C. Kirkman-Brown, Meurig T. Gallagher
Summary: This study revealed a significant lack of awareness among young adults in the UK regarding the potential impacts of gym lifestyles and supplementation on male infertility. Men were found to have a concerning lack of concern for their own fertility, with differences in awareness levels between men and women. It was also observed that men were more likely to consider making changes to their behavior if it had a long-term impact on their fertility compared to short-term effects.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Shachar Reuvenny, Michal Youngster, Almog Luz, Rohi Hourvitz, Ettie Maman, Micha Baum, Ariel Hourvitz
Summary: Using a machine-learning model to determine the optimal trigger days can improve the outcomes of antagonist protocol cycles in freeze-all or fresh transfer cycles, for all age groups. Implementing these models can more accurately predict the number of retrieved oocytes, optimizing physicians' decisions, balancing workloads, and creating more standardized yet patient-specific protocols.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Chao Chen, Qi Wen, Feng Deng, Rong Li, Ying Wang, Xiumei Zhen, Jing Hang
Summary: This study investigates the proteomic and phosphoproteomic differences in the endometrium of women with recurrent pregnancy loss (RPL) compared to healthy control women during different phases of the menstrual cycle. The results identify differentially expressed proteins and phosphorylated proteins, and highlight the insulin/cyclic nucleotide signalling pathway and AMPK/mTOR signalling pathway as major contributors to the abnormality of RPL endometrium. The findings provide insights into potential proteins associated with the pathogenesis of RPL and contribute to the identification of potential targets for RPL treatment.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Jaime Guerrero, Juan Carlos Castillo, Jorge Ten, Jose Antonio Ortiz, Belen Lledo, Domingo Orozco, Francisco Quereda, Andrea Bernabeu, Rafael Bernabeu
Summary: The study found no significant differences in clinical outcomes between using oocytes obtained from random-start protocols and those from conventional ovarian stimulation in oocyte donation treatments. Luteal-phase stimulation required longer stimulation and higher FSH consumption.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
