Journal
REPRODUCTIVE BIOMEDICINE ONLINE
Volume 24, Issue 4, Pages 377-380Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.rbmo.2011.12.007
Keywords
embryo; fertilization; gametes; gene expression; oviduct
Categories
Ask authors/readers for more resources
Deep body temperature in mammals is generally but incorrectly regarded as uniform. Alterations of temperature in oviducts and preovulatory Graafian follicles may play a vital role in gamete maturation, fertilization and early embryonic development. At a molecular level, the conformation of regulatory proteins is susceptible to changes in temperature. Deviation from physiological temperature during IVF procedures could thereby exert a profound influence on patterns of gene expression as the embryonic genome unfolds during early cleavage stages and act to generate specific anomalies. Systematic studies are urgently required. (C) 2012, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available