Review
Medicine, General & Internal
Lauren Lacey, Sibte Hassan, Sebastian Franik, Mourad W. Seif, M. Ahsan Akhtar
Summary: The effects of assisted hatching (AH) on live birth rates are uncertain and may increase the risk of multiple pregnancies. Although AH may offer a slightly increased chance of achieving a clinical pregnancy, the quality of data is low, and it is uncertain whether it influences miscarriage rates.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Endocrinology & Metabolism
Yuqing Jiang, Zhaoyang Shen, Jianmin Xu, Jing Zhu, Huan Wang, Wenhui Chen, Yingpu Sun, Qingling Yang
Summary: High sperm DNA fragmentation index (DFI) in overweight/obese women during ICSI cycles leads to decreased fertilization, cleavage, and high-quality embryo rates. The diminished capacity of oocytes to repair sperm DNA damage may be the cause of the decreased early developmental potential in embryos from overweight/obese patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Veterinary Sciences
Effrosyni Fatira, Milos Havelka, Taiju Saito, Jose Landeira, Marek Rodina, David Gela, Martin Psenicka
Summary: In this study, the researchers applied intracytoplasmic sperm injection (ICSI) technology to endangered sturgeons and found that it successfully produced embryos and larvae. Furthermore, molecular analysis showed genome integration of both egg and sperm donor species, demonstrating the potential of ICSI for assisted reproduction in sturgeons.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Endocrinology & Metabolism
Yubin Li, Qiyuan Chang, Qingyun Mai
Summary: This retrospective cohort study investigated the incidence, pregnancy and neonatal outcomes of monozygotic twins (MZTs) following assisted reproductive technology (ART) treatments, including IVF, ICSI, PGT, and TESA. The study found that the rate of MZTs was similar among the four ART groups, but the IVF group had a higher risk of pregnancy loss and early miscarriage, while the TESA group had a higher risk of twin-to-twin transfusion syndrome (TTTS).
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Yan Cheng, Huilan Xu, Chris Rissel, Philayrath Phongsavan, Limin Buchanan, Sarah Taki, Alison Hayes, Louise A. Baur, Li Ming Wen
Summary: This study aimed to evaluate the feasibility of using correction modeling to improve the accuracy of mother-reported child height and weight at 2 years. Correction modeling for BMI was conducted, and the indirect correction method showed better prediction of overweight status and agreement with measured values compared to the mother-reported measures.
SCIENTIFIC REPORTS
(2022)
Article
Obstetrics & Gynecology
Anna-Karina Aaris Henningsen, Signe Opdahl, Ulla-Britt Wennerholm, Aila Tiitinen, Steen Rasmussen, Liv Bente Romundstad, Christina Bergh, Mika Gissler, Julie Lyng Forman, Anja Pinborg
Summary: This study investigated the risk of major congenital malformations in live-born singletons conceived with intracytoplasmic sperm injection (ICSI) compared to in vitro fertilization (IVF). The findings showed that the risk of major malformations was slightly higher in live-born singletons conceived with fresh ICSI compared to fresh IVF. Children conceived through ICSI also had a higher risk of respiratory and chromosomal malformations, but the number of cases was small in each group. The risk of hypospadias was higher when ICSI was performed solely due to male factor infertility. These findings should be considered when choosing assisted reproductive technology methods for couples without male factor infertility.
FERTILITY AND STERILITY
(2023)
Article
Nutrition & Dietetics
Maria Mantzorou, Dimitrios Papandreou, Georgios K. Vasios, Eleni Pavlidou, Georgios Antasouras, Evmorfia Psara, Zainab Taha, Efthymios Poulios, Constantinos Giaginis
Summary: Breastfeeding plays an important role in preventing obesity and reducing long-term negative health outcomes for both mothers and children.
Review
Genetics & Heredity
Veena Unnikrishnan, John Kastelic, Jacob Thundathil
Summary: In cattle, the efficiency of ICSI is hindered by failed oocyte activation post sperm injection. Research focusing on proteins like Na/K-ATPase and PLC zeta is key to improving the success rate. Enhancing the efficiency of bovine ICSI has significant implications for the cattle breeding industry.
Article
Health Care Sciences & Services
Ambrogio P. Londero, Claudia Massarotti, Anjeza Xholli, Arrigo Fruscalzo, Angelo Cagnacci
Summary: This study reevaluated the association between assisted reproduction technologies (ART) and breech presentation, and found that both ART and other subfertility treatments (OST) were independent risk factors for breech at delivery. The prevalence of breech remained stable during the study period for both ART and OST.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Hematology
Tom Norris, Liina Mansukoski, Mark S. Gilthorpe, Mark Hamer, Rebecca Hardy, Laura D. Howe, Alun D. Hughes, Leah Li, Emma O'Donnell, Ken K. Ong, George B. Ploubidis, Richard J. Silverwood, Russell M. Viner, William Johnson
Summary: This study aimed to identify different classes of individuals with similar BMI trajectories and study their associations with cardiometabolic health. Results showed that individuals with high and stable BMI across childhood may have lower cardiometabolic disease risk than individuals who become overweight or obese later in adolescence.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Article
Clinical Neurology
Jens W. Horn, Tingting Feng, Bjorn Morkedal, Linn Beate Strand, Julie Horn, Kenneth Mukamal, Imre Janszky
Summary: Individuals with metabolic health issues are at greater risk of ischemic stroke, with hypertension being the most significant metabolic risk factor. Those who are metabolically healthy but overweight or obese have a similar risk of ischemic stroke as those with normal weight.
Article
Obstetrics & Gynecology
Wen Yao, Ying Chen, Haixia Yao, Qingyun Yao, Lan Wang, Meng Wang, Jing Yue
Summary: This retrospective cohort study investigated the relationship between uterine niche and reproductive outcomes of IVF/ICSI. The study found that women with uterine niche had lower live birth rate, positive HCG test rate, clinical pregnancy rate, and implantation rate during IVF/ICSI treatment. The study highlights the negative impact of uterine niche on fertility outcomes in women with cesarean section history.
FERTILITY AND STERILITY
(2023)
Article
Cell Biology
Andreana N. Holowatyj, Biljana Gigic, Christy A. Warby, Jennifer Ose, Tengda Lin, Petra Schrotz-King, Cornelia M. Ulrich, Jamie J. Bernard
Summary: The study found that human serum has the potential to stimulate growth in non-tumorigenic cells, but circulating levels of FGF2 were not significantly correlated. The transforming effects of human serum may require FGF2 activation of FGFR1.
Article
Peripheral Vascular Disease
Xijie Wang, Jie Hu, Sizhe Huang, Zhaogeng Yang, Yanhui Dong, Bin Dong, Jun Ma, Wannian Liang
Summary: As children grow older, those with a higher risk of overweight also have a higher risk of HBP. Children who transition from normal weight to overweight have a higher risk of developing HBP.
Article
Obstetrics & Gynecology
Ahmad Aboukhshaba, Nahid Punjani, Sofia Doukakis, Nikica Zaninovic, Gianpiero Palermo, Peter N. Schlegel
Summary: The study aimed to evaluate the impact of sperm characteristics on intracytoplasmic sperm injection (ICSI) outcomes in men with nonobstructive azoospermia (NOA) following microdissection testicular sperm extraction (mTESE). The results showed that specific sperm defects did not completely preclude the chance of clinical pregnancy. This study is the first comprehensive evaluation of the importance of these characteristics in ICSI outcomes.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Alice Newman-Sanders, Jackson C. Kirkman-Brown, Meurig T. Gallagher
Summary: This study revealed a significant lack of awareness among young adults in the UK regarding the potential impacts of gym lifestyles and supplementation on male infertility. Men were found to have a concerning lack of concern for their own fertility, with differences in awareness levels between men and women. It was also observed that men were more likely to consider making changes to their behavior if it had a long-term impact on their fertility compared to short-term effects.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Shachar Reuvenny, Michal Youngster, Almog Luz, Rohi Hourvitz, Ettie Maman, Micha Baum, Ariel Hourvitz
Summary: Using a machine-learning model to determine the optimal trigger days can improve the outcomes of antagonist protocol cycles in freeze-all or fresh transfer cycles, for all age groups. Implementing these models can more accurately predict the number of retrieved oocytes, optimizing physicians' decisions, balancing workloads, and creating more standardized yet patient-specific protocols.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Chao Chen, Qi Wen, Feng Deng, Rong Li, Ying Wang, Xiumei Zhen, Jing Hang
Summary: This study investigates the proteomic and phosphoproteomic differences in the endometrium of women with recurrent pregnancy loss (RPL) compared to healthy control women during different phases of the menstrual cycle. The results identify differentially expressed proteins and phosphorylated proteins, and highlight the insulin/cyclic nucleotide signalling pathway and AMPK/mTOR signalling pathway as major contributors to the abnormality of RPL endometrium. The findings provide insights into potential proteins associated with the pathogenesis of RPL and contribute to the identification of potential targets for RPL treatment.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Jaime Guerrero, Juan Carlos Castillo, Jorge Ten, Jose Antonio Ortiz, Belen Lledo, Domingo Orozco, Francisco Quereda, Andrea Bernabeu, Rafael Bernabeu
Summary: The study found no significant differences in clinical outcomes between using oocytes obtained from random-start protocols and those from conventional ovarian stimulation in oocyte donation treatments. Luteal-phase stimulation required longer stimulation and higher FSH consumption.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)