Article
Immunology
Venkatappa Vani, Satya S. Vasan, Satish K. Adiga, Samson Roy Varsha, Geetanjali Sachdeva, Pratap Kumar, Polani B. Seshagiri
Summary: This study investigated the association of embryo-secreted soluble human leukocyte antigen-G (sHLA-G) with developing embryos and its ability to predict successful pregnancy outcome. The levels of sHLA-G varied within and across clinics and different stages of embryonic development. While there was no significant correlation between sHLA-G levels and embryo morphology scores, levels of sHLA-G were significantly higher in live-birth cases compared to no-birth cases, particularly in blastocysts-ETs. The results suggest that sHLA-G can be a valuable biomarker to predict live-birth outcome in assisted reproductive technology.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2021)
Article
Obstetrics & Gynecology
Emily Sadecki, Laura Rust, David L. Walker, Jolene R. Fredrickson, Anthony Krenik, Tana Kim, Amy L. Weaver, Yulian Zhao
Summary: The study suggests that using PGT-A for embryo transfers results in significantly higher live birth rates compared to non-PGT-A transfers. However, this difference was not consistent at a per-retrieval level, indicating a need for further investigation.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Letter
Medicine, General & Internal
Adriana J. Wong, Alan H. DeCherney
Summary: This article points out a limitation of a clinical study, stating that its conclusions have certain limitations and may not be applicable to all clinical practices. The choice of outcome measures in the study may also lack clinical relevance, and there are restrictions on the study population, which raises concerns about the incidence of aneuploidy among the subjects.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Obstetrics & Gynecology
Giovanni Coticchio, Kenji Ezoe, Cristina Lagalla, Kiyoe Shimazaki, Kazuki Ohata, Maya Ninomiya, Natsuki Wakabayashi, Tadashi Okimura, Kazuo Uchiyama, Keiichi Kato, Andrea Borini
Summary: The study showed that the exclusion and extrusion of cells during blastocyst formation have a significant impact on the embryo development and clinical outcomes, especially with negative effects on pregnancy and live birth rates.
HUMAN REPRODUCTION
(2021)
Article
Veterinary Sciences
Yasumitsu Masuda, Ryo Hasebe, Yasushi Kuromi, Masayoshi Kobayashi, Kanako Urataki, Mitsugu Hishinuma, Tetsuya Ohbayashi, Ryo Nishimura
Summary: The study utilized optical coherence tomography (OCT) to evaluate the quality of bovine preimplantation embryos and found that OCT imaging can be used to select high-quality embryos for transfer. Results suggest that TE volume may be a key parameter for the evaluation of bovine embryos, indicating the potential of OCT in improving embryo selection for successful pregnancies.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Endocrinology & Metabolism
Esther Dos Santos, Hadia Moindjie, Valerie Serazin, Lucie Arnould, Yoann Rodriguez, Khadija Fathallah, Eytan R. Barnea, Francois Vialard, Marie-Noelle Dieudonne
Summary: The study demonstrates that PIF can enhance decidualization and limit trophoblast invasion by increasing the production of endometrial factors. PIF appears to be a pivotal player in the human embryo implantation process by controlling both trophoblast and endometrial cells.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Jie Wang, Zhenyu Diao, Junshun Fang, Lihua Zhu, Zhipeng Xu, Fei Lin, Ningyuan Zhang, Linjun Chen
Summary: This retrospective study suggests that the day 3 embryo cell number has an influence on the clinical pregnancy and live birth rates of day 5 single blastocyst transfer in frozen embryo transfer (FET) cycles. As the day 3 embryo cell number increases, the clinical pregnancy and live birth rates also increase, especially when fair- and poor-quality blastocysts are transferred.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Endocrinology & Metabolism
Jihui Ai, Lei Jin, Yu Zheng, Peiwen Yang, Bo Huang, Xiyuan Dong
Summary: The blastocyst expansion stage, ICM grade, and TE grade are all associated with pregnancy outcomes. ICM grade is the strongest predictor of live birth. A blastocyst with stage 4-5, ICM grade A, and TE grade A/B should be given priority for single embryo transfer.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Reitan Ribeiro, Maria Cristina Anselmi, Gunther Alex Schneider, Jose Pio Rodrigues Furtado, Mohamed Gaber Mohamed Abau Shwareb, Jose Clemente Linhares
Summary: This is the first reported case of a live birth after uterine transposition, pelvic radiotherapy, and subsequent uterine repositioning. A 28-year-old nulligravid woman underwent uterine transposition before receiving pelvic and thoracic radiation therapy. After successful radiation treatment, her uterus was reimplanted in the pelvis. The patient became pregnant and delivered a healthy baby after 36 weeks of gestation.
FERTILITY AND STERILITY
(2023)
Review
Developmental Biology
Masoumeh Esmaeilivand, Ali Abedelahi, Kobra Hamdi, Laya Farzadi, Sepide Goharitaban, Amir Fattahi, Behrooz Niknafs
Summary: During the IVF cycle, embryo-secreted miRNAs can be used as potential non-invasive biomarkers for selecting the best embryos, although there are few human studies on the association between ART outcomes and miRNAs in SCM.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2022)
Article
Multidisciplinary Sciences
Sargunadevi Sivanantham, Mahalakshmi Saravanan, Nidhi Sharma, Jayashree Shrinivasan, Ramesh Raja
Summary: This study confirms that the morphology of the inner cell mass (ICM) of the blastocyst is a stronger predictor of implantation and clinical pregnancy than that of the trophectoderm (TE), and can be utilized as a biomarker of viability.
Article
Biochemistry & Molecular Biology
Maria Belen Rabaglino, Dessie Salilew-Wondim, Adriana Zolini, Dawit Tesfaye, Michael Hoelker, Pat Lonergan, Peter J. J. Hansen
Summary: This study developed a gene signature model to predict embryonic competence for survival by integrating transcriptomic data from blastocysts and elongating conceptuses. The potential biomarkers were validated with independent embryonic data sets using machine-learning algorithms. The results showed that the predictions of embryonic development fate based on these biomarkers were highly accurate.
Article
Obstetrics & Gynecology
Mengjie Wei, Guangen Feng, Xiaoyan Mao, Ling Wu, Weiran Chai, Jie Zhang
Summary: This study found that a previous history of naturally conceived tubal ectopic pregnancy (TEP) does not have an adverse effect on reproductive and perinatal outcomes in subsequent frozen-thawed embryo transfer (FET) cycles.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Endocrinology & Metabolism
Xian Wu, Wen-jie Zhou, Bu-fang Xu, Qian Chen, Lan Xia, Shen Zhao, Hui-hui Xu, Ai-jun Zhang, Zhi-hong Niu
Summary: The study suggests that single good-quality blastocyst transfer is recommended for women of all ages. When good-quality cleavage embryos are available, the choice of single or double embryo transfer with good- or average-quality embryo should depend on the age of women. Double embryo transfer with the highest possible grade of embryos is recommended for women aged >= 40 years.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Xuanyou Zhou, Xueli Liu, Weihui Shi, Mujin Ye, Songchang Chen, Chenming Xu
Summary: The study found that there was no significant association between blastocyst mtDNA content and live birth rate or embryo implantation potential. Therefore, mtDNA content does not seem to be a potential biomarker for embryo transfer outcomes based on the existing testing tools. Embryos with elevated mtDNA content still have development potential for successful live birth.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Cell Biology
Dania Morgoulis, Peter Berenstein, Simona Cazacu, Gila Kazimirsky, Amir Dori, Eytan R. Barnea, Chaya Brodie
CELL DEATH & DISEASE
(2019)
Article
Obstetrics & Gynecology
Gerard H. A. Visser, Gian Carlo Di Renzo, Steven L. Spitalnik, Gerard H. A. Visser, Gian Carlo Di Renzo, Diogo Ayres-de-Campos, Maria Fernanda Escobar, Eytan Barnea, P. K. Shah, Anwar Nasser, Luc de Bernis, Luming Sun, Wanda Kay Nicholson, Isabel Lloyd, Salimah Walani, Gerhard Theron, William Stones
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2019)
Article
Obstetrics & Gynecology
William Stones, Gerard H. A. Visser, Gerhard Theron, Gian Carlo Di Renzo, Diogo Ayres-de-Campos, Maria Fernanda Escobar, Eytan Barnea, P. K. Shah, Anwar Nassar, Luc de Bernis, Luming Sun, Wanda Kay Nicholson, Isabel Lloyd, Salimah Walani
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2019)
Article
Obstetrics & Gynecology
Diogo Ayres-de-Campos, William Stones, Gerhard Theron, Gerard H. A. Visser, GianCarlo Di Renzo, Maria Fernanda Escobar, Eytan Barnea, Permanand K. Shah, Anwar Nassar, Luc de Bernis, Luming Sun, Wanda K. Nicholson, Isabel Lloyd, Salimah Walani
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2019)
Editorial Material
Obstetrics & Gynecology
Anwar H. Nassar, Gerard H. A. Visser, Diogo Ayres-de-Campos, Ajay Rane, Sandhya Gupta, Eytan Barnea, Luc de Bernis, Gian Carlo Di Renzo, Maria Fernanda Escobar, Isabel Lloyd, Anwar H. Nassar, Wanda Kay Nicholson, P. K. Shah, William Stones, Luming Sun, Gerhard Theron, Salimah Walani
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2019)
Article
Multidisciplinary Sciences
Marialuigia Spinelli, Celine Boucard, Fiorella Di Nicuolo, Valerie Haesler, Roberta Castellani, Alfredo Pontecorvi, Giovanni Scambia, Chiara Granieri, Eytan R. Barnea, Daniel Surbek, Martin Mueller, Nicoletta Di Simone
Article
Obstetrics & Gynecology
Wanda K. Nicholson, William Stones, Gerard H. A. Visser, Eytan R. Barnea, Anwar H. Nassar
Summary: Hypertensive disorders are a major cause of maternal morbidity and mortality worldwide. Partnership between healthcare professionals and policy makers, along with increased resources, training, and postpartum care, is essential to reduce the risks associated with these conditions. Culturally appropriate education and sustained efforts can help prevent eclampsia and its complications.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Review
Obstetrics & Gynecology
Eytan R. Barnea, Wanda Nicholson, Gerhard Theron, Diana Ramasauskaite, Michael Stark, S. Mark Albini, Anwar H. Nassar
Summary: Health systems and care approaches vary widely worldwide, leading to highly variable maternal-newborn care and outcomes. An integrated care model is proposed to improve maternal safety and wellbeing, with successful implementation in both high- and low-resource countries.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Article
Obstetrics & Gynecology
Anwar H. Nassar, Gerard H. A. Visser, Wanda Kay Nicholson, Diana Ramasauskaite, Yoon Ha Kim, Eytan R. Barnea
Summary: During pregnancy, influenza and Tdap vaccines are strongly recommended, with other vaccines offered based on risk factors. The FIGO Committee endorses vaccinating all pregnant women against influenza during the influenza season and preferably between the 27th and 36th weeks for Tdap.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Article
Obstetrics & Gynecology
Gerard H. A. Visser, Wanda K. Nicholson, Eytan R. Barnea, Diana Ramasauskaite, Anwar H. Nassar
Summary: The International Federation of Gynecology and Obstetrics suggests that local or regional growth charts are likely best for identifying newborns at highest risk, but international standards for growth may also be used when paired with locally appropriate risk interpretation thresholds.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Article
Biotechnology & Applied Microbiology
Maria Rosaria Raspollini, Ilaria Montagnani, Paolo Cirri, Gianna Baroni, Alessia Cimadamore, Marina Scarpelli, Liang Cheng, Antonio Lopez-Beltran, Rodolfo Montironi, Eytan R. Barnea
INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS
(2020)
Meeting Abstract
Obstetrics & Gynecology
Marialuigia Spinelli, Celine Boucard, Fiorella Di Nicuolo, Roberta Castellani, Alfredo Pontecorvi, Giovanni Scambia, Chiara Granieri, Eytan Barnea, Daniel Surbek, Nicoletta Di Simone, Martin Mueller
REPRODUCTIVE SCIENCES
(2020)
Meeting Abstract
Physiology
R. Immler, W. Nadolni, V. Morikis, I. Rohwedder, J. Tilgner, J. Grommes, A. Bertsch, A. Yevtushenko, A. R. M. Kurz, O. Soehnlein, M. Moser, T. Gudermann, S. Dietzel, E. Barnea, S. I. Simon, S. Zierler, M. Pruenster, M. Sperandio
Meeting Abstract
Physiology
M. G. Kovacs, L. Kiscsatari, Z. Varga, B. Kovari, G. Fabian, G. Cserni, T. Thum, T. Csont, S. Batkai, E. Barnea, Z. Kahan, M. Sarkozy
Meeting Abstract
Obstetrics & Gynecology
Marialuigia Spinelli, Daniel Surbek, Andreina Schoeberlein, Irene Keller, Angelique Bordey, Eytan Barnea, Michael Paidas, Martin Mueller
REPRODUCTIVE SCIENCES
(2019)