Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cells

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

(2016) J. Julie Wu et al.   Aging-US

Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMP

(2015) Amicia D. Elliott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression

(2014) Bas Brouwers et al.   Cell Metabolism

Marked Expansion of Exocrine and Endocrine Pancreas With Incretin Therapy in Humans With Increased Exocrine Pancreas Dysplasia and the Potential for Glucagon-Producing Neuroendocrine Tumors

(2013) A. E. Butler et al.   DIABETES

Incretin Action in the Pancreas: Potential Promise, Possible Perils, and Pathological Pitfalls

(2013) D. J. Drucker   DIABETES

Exendin-4 Improves β-Cell Function in Autophagy-Deficient β-Cells

(2013) Hiroko Abe et al.   ENDOCRINOLOGY

Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells

(2013) Young-Sun Lee et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion

(2012) Sindhu Rajan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Human GLP-1 Analog Liraglutide and the Pancreas

(2012) Niels C.B. Nyborg et al.   DIABETES

Studies in rodents with the dipeptidyl peptidase-4 inhibitor vildagliptin to evaluate possible drug-induced pancreatic histological changes that are predictive of pancreatitis and cancer development in man

(2012) S. J. Busch et al.   DIABETES OBESITY & METABOLISM

Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea

(2012) S. Seino   DIABETOLOGIA

Impact of the Dipeptidyl Peptidase-4 Inhibitor Vildagliptin on Glucose Tolerance and β-Cell Function and Mass in Insulin Receptor Substrate-2-Knockout Mice Fed a High-Fat Diet

(2012) Koichiro Sato et al.   ENDOCRINOLOGY

Discovery and development of exenatide: the first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1

(2012) David G Parkes et al.   Expert Opinion on Drug Discovery

Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?

(2011) J. N. Walker et al.   DIABETES OBESITY & METABOLISM

Conditional Gene Targeting in Mouse Pancreatic  -Cells: Analysis of Ectopic Cre Transgene Expression in the Brain

(2010) B. Wicksteed et al.   DIABETES

Sitagliptin: review of preclinical and clinical data regarding incidence of pancreatitis

(2010) S. S. Engel et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo

(2009) Dan Kawamori et al.   Cell Metabolism

Autophagy in human type 2 diabetes pancreatic beta cells

(2009) M. Masini et al.   DIABETOLOGIA

Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

(2008) Hye Seung Jung et al.   Cell Metabolism

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism