Impact of exercise on oocyte quality in the POLG mitochondrial DNA mutator mouse

Genetic studies in mice directly link oocytes produced during adulthood to ovarian function and natural fertility

(2017) Ning Wang et al.   Scientific Reports

Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis

(2016) Adeel Safdar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Rodent models for resolving extremes of exercise and health

(2016) Fleur C. Garton et al.   PHYSIOLOGICAL GENOMICS

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

(2015) Assaf Ben-Meir et al.   AGING CELL

Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain

(2015) Joanne Clark-Matott et al.   NEUROBIOLOGY OF AGING

Leisure Time Physical Activity and Mortality

(2015) Hannah Arem et al.   JAMA Internal Medicine

Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice

(2015) Adeel Safdar et al.   Skeletal Muscle

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

Germline Energetics, Aging, and Female Infertility

(2013) Jonathan L. Tilly et al.   Cell Metabolism

Embryo developmental capability and pregnancy outcome are related to the mitochondrial DNA copy number and ooplasmic volume

(2013) Yukitaka Murakoshi et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Age-Associated Metabolic and Morphologic Changes in Mitochondria of Individual Mouse and Hamster Oocytes

(2013) Fatma Simsek-Duran et al.   PLoS One

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse

(2012) Lloye M. Dillon et al.   HUMAN MOLECULAR GENETICS

Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis

(2012) Steven C. Moore et al.   PLOS MEDICINE

The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation

(2011) Hakan E. Duran et al.   FERTILITY AND STERILITY

The contribution of mitochondrial function to reproductive aging

(2011) Yaakov Bentov et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis

(2011) Adeel Safdar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Associations of physical activity and diet with the onset of menopause in Japanese women

(2011) Chisato Nagata et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

The p53 family: guardians of maternal reproduction

(2011) Arnold J. Levine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

(2011) A. Safdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies

(2011) K. Selesniemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Mitochondrial DNA Copy Number in Mammalian Fertility1

(2010) Timothy Wai et al.   BIOLOGY OF REPRODUCTION

Physical Activity, Function, and Longevity Among the Very Old

(2009) Jochanan Stessman   ARCHIVES OF INTERNAL MEDICINE

Ovarian Aging: Mechanisms and Clinical Consequences

(2009) F. J. Broekmans et al.   ENDOCRINE REVIEWS

The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients

(2009) Yaakov Bentov et al.   FERTILITY AND STERILITY

Mitochondrial functions on oocytes and preimplantation embryos

(2009) Li-ya Wang et al.   Journal of Zhejiang University-SCIENCE B

Reduced Disability and Mortality Among Aging Runners

(2008) Eliza F. Chakravarty   ARCHIVES OF INTERNAL MEDICINE