Extracellular matrix (ECM) activates β-catenin signaling in uterine fibroids

Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers

(2016) Miika Mehine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium

(2016) Preety Bajwa et al.   Oncotarget

Uterine fibroids

(2016) Elizabeth A. Stewart et al.   Nature Reviews Disease Primers

Extracellular matrix stiffness dictates Wnt expression through integrin pathway

(2016) Jing Du et al.   Scientific Reports

Med12 gain-of-function mutation causes leiomyomas and genomic instability

(2015) Priya Mittal et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxytocin activates NF-κB-mediated inflammatory pathways in human gestational tissues

(2015) Sung Hye Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Mediator complex: a central integrator of transcription

(2015) Benjamin L. Allen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas

(2014) N Mäkinen et al.   BRITISH JOURNAL OF CANCER

Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth

(2014) Masanori Ono et al.   FERTILITY AND STERILITY

Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids

(2014) Sunil K. Halder et al.   MOLECULAR GENETICS AND GENOMICS

Mediator complex subunit 12 exon 2 mutation analysis in different subtypes of smooth muscle tumors confirms genetic heterogeneity

(2013) Marieke A. de Graaff et al.   HUMAN PATHOLOGY

Uterine Fibroids

(2013) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Uterine Leiomyomas by Whole-Genome Sequencing

(2013) Miika Mehine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Paracrine activation of WNT/ -catenin pathway in uterine leiomyoma stem cells promotes tumor growth

(2013) M. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant expression and regulation of NR2F2 and CTNNB1 in uterine fibroids

(2013) Marina Zaitseva et al.   REPRODUCTION

MED12 mutations in uterine fibroids-their relationship to cytogenetic subgroups

(2012) Dominique Nadine Markowski et al.   INTERNATIONAL JOURNAL OF CANCER

MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

(2011) N. Makinen et al.   SCIENCE

Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling

(2010) P. P. Rocha et al.   DEVELOPMENT

Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice1

(2009) Pradeep S. Tanwar et al.   BIOLOGY OF REPRODUCTION

Incidence, aetiology and epidemiology of uterine fibroids

(2008) Stanley Okolo   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY