Good planning and serendipity: exploiting the Cre/Lox system in the testis

Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of “floxed” alleles

(2010) Won Jae Huh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary

(2010) Chen-Che J Huang et al.   BMC DEVELOPMENTAL BIOLOGY

Deletion of Androgen Receptor in the Smooth Muscle of the Seminal Vesicles Impairs Secretory Function and Alters Its Responsiveness to Exogenous Testosterone and Estradiol

(2010) Michelle Welsh et al.   ENDOCRINOLOGY

The Power of Mouse Genetics to Study Spermatogenesis

(2010) A. N. Yatsenko et al.   JOURNAL OF ANDROLOGY

Androgen Action via Testicular Arteriole Smooth Muscle Cells Is Important for Leydig Cell Function, Vasomotion and Testicular Fluid Dynamics

(2010) Michelle Welsh et al.   PLoS One

Genome-wide ENU Mutagenesis for the Discovery of Novel Male Fertility Regulators

(2010) Duangporn Jamsai et al.   Systems Biology in Reproductive Medicine

A Single, Mild, Transient Scrotal Heat Stress Causes Hypoxia and Oxidative Stress in Mouse Testes, Which Induces Germ Cell Death1

(2009) Catriona Paul et al.   BIOLOGY OF REPRODUCTION

Constitutive WNT/Beta-Catenin Signaling in Murine Sertoli Cells Disrupts Their Differentiation and Ability to Support Spermatogenesis1

(2009) Pradeep S. Tanwar et al.   BIOLOGY OF REPRODUCTION

Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism

(2009) Ivraym B. Barsoum et al.   DEVELOPMENTAL BIOLOGY

Inactivation of Numb and Numblike in spermatogonial stem cells by cell-permeant Cre recombinase

(2009) Laura Grisanti et al.   DIFFERENTIATION

Sertoli Cell Androgen Receptor DNA Binding Domain Is Essential for the Completion of Spermatogenesis

(2009) Patrick Lim et al.   ENDOCRINOLOGY

Androgen action via testicular peritubular myoid cells is essential for male fertility

(2009) Michelle Welsh et al.   FASEB JOURNAL

Tools for the genetic analysis of germ cells

(2009) Shirley S. Hammond et al.   GENESIS

Phenotyping male infertility in the mouse: how to get the most out of a 'non-performer'

(2009) C. L. Borg et al.   HUMAN REPRODUCTION UPDATE

Conditional Gene Targeting in Mouse High Endothelial Venules

(2009) H. Kawashima et al.   JOURNAL OF IMMUNOLOGY

Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2

(2009) A. Y. Higashi et al.   JOURNAL OF IMMUNOLOGY

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

(2009) Anthony D. Krentz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNA-Binding Protein NANOS2 Is Required to Maintain Murine Spermatogonial Stem Cells

(2009) A. Sada et al.   SCIENCE

Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways

(2008) Hitomi Suzuki et al.   DEVELOPMENTAL BIOLOGY

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth

(2008) George B. John et al.   DEVELOPMENTAL BIOLOGY

Nanos2 suppresses meiosis and promotes male germ cell differentiation

(2008) A. Suzuki et al.   GENES & DEVELOPMENT

Generation ofCyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis

(2008) Phillip J. Bridges et al.   GENESIS

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

(2008) Patricia I. Sadate-Ngatchou et al.   GENESIS

The IRG mouse: A two-color fluorescent reporter for assessing Cre-mediated recombination and imaging complex cellular relationships in situ

(2008) Rita De Gasperi et al.   GENESIS

Stabilization of β-catenin in XY gonads causes male-to-female sex-reversal

(2008) Danielle M. Maatouk et al.   HUMAN MOLECULAR GENETICS

Do heat stress and deficits in DNA repair pathways have a negative impact on male fertility?

(2008) C. Paul et al.   MOLECULAR HUMAN REPRODUCTION

Essential Roles of COUP-TFII in Leydig Cell Differentiation and Male Fertility

(2008) Jun Qin et al.   PLoS One

Intra-testicular injection of adenoviral constructs results in Sertoli cell-specific gene expression and disruption of the seminiferous epithelium

(2008) R P Hooley et al.   REPRODUCTION