Cardiac repair and restoration using human embryonic stem cells

The promise of human embryonic stem cells in aging-associated diseases

(2016) Odessa Yabut et al.   Aging-US

Embryonic stem cell pioneer Geron exits field, cuts losses

(2012) Simon Frantz   NATURE BIOTECHNOLOGY

miR-125b Promotes Early Germ Layer Specification through Lin28/let-7d and Preferential Differentiation of Mesoderm in Human Embryonic Stem Cells

(2012) Sharon S. Y. Wong et al.   PLoS One

Concise Review: The Role of Clinical Trials in Deciphering Mechanisms of Action of Cardiac Cell-Based Therapy

(2012) Viky Y. Suncion et al.   Stem Cells Translational Medicine

Chromatin Connections to Pluripotency and Cellular Reprogramming

(2011) Stuart H. Orkin et al.   CELL

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

Short-Term Immunosuppression Promotes Engraftment of Embryonic and Induced Pluripotent Stem Cells

(2011) Jeremy I. Pearl et al.   Cell Stem Cell

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

(2011) Frederick Anokye-Danso et al.   Cell Stem Cell

Homologous Recombination in Human Embryonic Stem Cells: A Tool for Advancing Cell Therapy and Understanding and Treating Human Disease

(2011) Andrew D. Leavitt et al.   CTS-Clinical and Translational Science

Myocardial improvement with human embryonic stem cell-derived cardiomyocytes enriched by p38MAPK inhibition

(2011) Yerem Yeghiazarians et al.   CYTOTHERAPY

Intramyocardial Injection of Autologous Cardiospheres or Cardiosphere-Derived Cells Preserves Function and Minimizes Adverse Ventricular Remodeling in Pigs With Heart Failure Post-Myocardial Infarction

(2011) Shuo-Tsan Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

Somatic coding mutations in human induced pluripotent stem cells

(2011) Athurva Gore et al.   NATURE

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

(2011) Ryan Lister et al.   NATURE

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells

(2011) Nicole C Dubois et al.   NATURE BIOTECHNOLOGY

NKX2-5 eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

(2011) David A Elliott et al.   NATURE METHODS

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

An Engineered Cardiac Reporter Cell Line Identifies Human Embryonic Stem Cell-Derived Myocardial Precursors

(2011) Carissa Ritner et al.   PLoS One

Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

(2010) Yoav Mayshar et al.   Cell Stem Cell

Timed inhibition of p38MAPK directs accelerated differentiation of human embryonic stem cells into cardiomyocytes

(2010) Meenakshi Gaur et al.   CYTOTHERAPY

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype

(2010) Mari Pekkanen-Mattila et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The International Stem Cell Banking Initiative (ISCBI): raising standards to bank on

(2010) Jeremy Micah Crook et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

(2010) Elisa Närvä et al.   NATURE BIOTECHNOLOGY

NANOG Reporter Cell Lines Generated by Gene Targeting in Human Embryonic Stem Cells

(2010) Yvonne Fischer et al.   PLoS One

Implantation of Mouse Embryonic Stem Cell-Derived Cardiac Progenitor Cells Preserves Function of Infarcted Murine Hearts

(2010) Nicolas Christoforou et al.   PLoS One

Cardiac regeneration using human embryonic stem cells: producing cells for future therapy

(2010) Sharon SY Wong et al.   Regenerative Medicine

In Vivo Assessment of the Electrophysiological Integration and Arrhythmogenic Risk of Myocardial Cell Transplantation Strategies

(2010) Lior Gepstein et al.   STEM CELLS

High-Throughput Tracking of Pluripotent Human Embryonic Stem Cells with Dual Fluorescence Resonance Energy Transfer Molecular Beacons

(2010) Frank W. King et al.   STEM CELLS AND DEVELOPMENT

Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture

(2009) Carolyn Y. Sargent et al.   BIOTECHNOLOGY AND BIOENGINEERING

Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium

(2009) Anke M. Smits et al.   CARDIOVASCULAR RESEARCH

MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

(2009) Na Xu et al.   CELL

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

(2009) Dohoon Kim et al.   Cell Stem Cell

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

Heart Disease and Stroke Statistics—2009 Update

(2009) et al.   CIRCULATION

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Imaging Survival and Function of Transplanted Cardiac Resident Stem Cells

(2009) Zongjin Li et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Injection of Bone Marrow Cell Extract Into Infarcted Hearts Results in Functional Improvement Comparable to Intact Cell Therapy

(2009) Yerem Yeghiazarians et al.   MOLECULAR THERAPY

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

(2009) Lei Bu et al.   NATURE

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

(2009) Jun K. Takeuchi et al.   NATURE

Nongenetic method for purifying stem cell–derived cardiomyocytes

(2009) Fumiyuki Hattori et al.   NATURE METHODS

Electrical stimulation systems for cardiac tissue engineering

(2009) Nina Tandon et al.   Nature Protocols

Lentiviral Vectors and Protocols for Creation of Stable hESC Lines for Fluorescent Tracking and Drug Resistance Selection of Cardiomyocytes

(2009) Hiroko Kita-Matsuo et al.   PLoS One

Prevascularization of cardiac patch on the omentum improves its therapeutic outcome

(2009) T. Dvir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Functional Ventricular Heart Muscle from Mouse Ventricular Progenitor Cells

(2009) I. J. Domian et al.   SCIENCE

Gene Targeting in a HUES Line of Human Embryonic Stem Cells Via Electroporation

(2009) Katherine M. Ruby et al.   STEM CELLS

Subpopulations of Human Embryonic Stem Cells With Distinct Tissue-Specific Fates Can Be Selected From Pluripotent Cultures

(2009) Frank W. King et al.   STEM CELLS AND DEVELOPMENT

Cardiomyogenic Differentiation of Embryoid Bodies Is Promoted by Rotary Orbital Suspension Culture

(2009) Carolyn Y. Sargent et al.   TISSUE ENGINEERING PART A

Transplantation of a Tissue-Engineered Human Vascularized Cardiac Muscle

(2009) Ayelet Lesman et al.   TISSUE ENGINEERING PART A

Pulsatile perfusion bioreactor for cardiac tissue engineering

(2008) Melissa A. Brown et al.   BIOTECHNOLOGY PROGRESS

The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases

(2008) I. L. Weissman et al.   BLOOD

Genetic Modification of Human Embryonic Stem Cells for Derivation of Target Cells

(2008) Antonietta Giudice et al.   Cell Stem Cell

MicroRNA Regulation of Cell Lineages in Mouse and Human Embryonic Stem Cells

(2008) Kathryn N. Ivey et al.   Cell Stem Cell

Human Embryonic Stem Cell–Derived Cardiomyocytes and Cardiac Repair in Rodents

(2008) Linda W. van Laake et al.   CIRCULATION RESEARCH

Highly enriched cardiomyocytes from human embryonic stem cells

(2008) X.Q. Xu et al.   CYTOTHERAPY

Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells

(2008) Xiu Qin Xu et al.   DIFFERENTIATION

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE

Human embryonic stem cells reveal recurrent genomic instability at 20q11.21

(2008) Nathalie Lefort et al.   NATURE BIOTECHNOLOGY

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

(2008) Harald C Ott et al.   NATURE MEDICINE

Cardiac tissue engineering using perfusion bioreactor systems

(2008) Milica Radisic et al.   Nature Protocols

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK

(2007) Ralph Graichen et al.   DIFFERENTIATION