Translational prospects for human induced pluripotent stem cells

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

(2010) Jeffrey D. Rothstein   ANNALS OF NEUROLOGY

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

(2010) Miguel Angel Esteban et al.   Cell Stem Cell

Definition of human autoimmunity — autoantibodies versus autoimmune disease

(2009) Ana Lleo et al.   AUTOIMMUNITY REVIEWS

The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells

(2009) Noritaka Yokoo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes

(2009) Tomofumi Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells

(2009) D. S. Kaufman   BLOOD

iPS Cells: Mapping the Policy Issues

(2009) Amy Zarzeczny et al.   CELL

A Fresh Look at iPS Cells

(2009) Shinya Yamanaka   CELL

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

(2009) Zhihua Song et al.   CELL RESEARCH

Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

(2009) Yoshinori Yoshida et al.   Cell Stem Cell

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

(2009) Dohoon Kim et al.   Cell Stem Cell

Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures

(2009) Mark H. Chin et al.   Cell Stem Cell

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

From stem cells and cadaveric matrix to engineered organs

(2009) Doris A Taylor   CURRENT OPINION IN BIOTECHNOLOGY

Transcriptional competence in pluripotency

(2009) E. V.S. Raghu Ram et al.   GENES & DEVELOPMENT

Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells

(2009) J. Xu et al.   GENES & DEVELOPMENT

An identification of the novel combination therapy for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells

(2009) Hisashi Moriguchi et al.   HEPATOLOGY

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

(2009) Karim Si-Tayeb et al.   HEPATOLOGY

Generation of functional human hepatic endoderm from human induced pluripotent stem cells

(2009) Gareth J. Sullivan et al.   HEPATOLOGY

Toward a wide-field retinal prosthesis

(2009) Hossein Ameri et al.   Journal of Neural Engineering

Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

(2009) Yasuhiro Kazuki et al.   MOLECULAR THERAPY

Adult mice generated from induced pluripotent stem cells

(2009) Michael J. Boland et al.   NATURE

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Direct reprogramming of human neural stem cells by OCT4

(2009) Jeong Beom Kim et al.   NATURE

iPS cells produce viable mice through tetraploid complementation

(2009) Xiao-yang Zhao et al.   NATURE

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

(2009) Jie Deng et al.   NATURE BIOTECHNOLOGY

Variation in the safety of induced pluripotent stem cell lines

(2009) Kyoko Miura et al.   NATURE BIOTECHNOLOGY

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

(2009) Madeleine P Ball et al.   NATURE BIOTECHNOLOGY

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

Induced pluripotent stem cells and reprogramming: seeing the science through the hype

(2009) Juan Carlos Izpisúa Belmonte et al.   NATURE REVIEWS GENETICS

Generation of retinal cells from mouse and human induced pluripotent stem cells

(2009) Yasuhiko Hirami et al.   NEUROSCIENCE LETTERS

Vision 1 Year after Gene Therapy for Leber's Congenital Amaurosis

(2009) Artur V. Cideciyan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells

(2009) Maria C. N. Marchetto et al.   PLoS One

Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

(2009) Amanda-Jayne Carr et al.   PLoS One

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

(2009) M. Blurton-Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

(2009) Dan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Clone- and Gene-Specific Aberrations of Parental Imprinting in Human Induced Pluripotent Stem Cells

(2009) Marjorie Pick et al.   STEM CELLS

Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells

(2009) David E. Buchholz et al.   STEM CELLS

Long-Term Safety and Function of RPE from Human Embryonic Stem Cells in Preclinical Models of Macular Degeneration

(2009) Bin Lu et al.   STEM CELLS

Directed Differentiation of Human-Induced Pluripotent Stem Cells Generates Active Motor Neurons

(2009) Saravanan Karumbayaram et al.   STEM CELLS

Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

(2009) Wenlin Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Obstacles and Opportunities in New Drug Development

(2008) KI Kaitin   CLINICAL PHARMACOLOGY & THERAPEUTICS

Inhibitor Development

(2008) J. ASTERMARK et al.   HAEMOPHILIA

Tackling the epigenome in the pluripotent stem cells

(2008) Xiaodong Zhao et al.   Journal of Genetics and Genomics

Non-inhibitory antibodies impede lysosomal storage reduction during enzyme replacement therapy of a lysosomal storage disease

(2008) Ulrich Matzner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Induced pluripotent stem cells from a spinal muscular atrophy patient

(2008) Allison D. Ebert et al.   NATURE

Regulatory networks define phenotypic classes of human stem cell lines

(2008) Franz-Josef Müller et al.   NATURE

Patenting pluripotence: the next battle for stem cell intellectual property

(2008) Katja Triller Vrtovec et al.   NATURE BIOTECHNOLOGY

Marked differences in differentiation propensity among human embryonic stem cell lines

(2008) Kenji Osafune et al.   NATURE BIOTECHNOLOGY

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE

Regulatory Issues for Personalized Pluripotent Cells

(2008) Maureen L. Condic et al.   STEM CELLS