Journal
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
Volume 22, Issue 14, Pages 2195-2202Publisher
WILEY
DOI: 10.1002/rcm.3604
Keywords
-
Funding
- NERC [NE/E013546/1] Funding Source: UKRI
- Natural Environment Research Council [NE/E013546/1, NE/C001737/1, NER/A/S/2003/00489] Funding Source: researchfish
Ask authors/readers for more resources
The behaviour of a series of hydroxamate siderophores - microbially produced iron complexes - was investigated using electrospray ionisation mass spectrometry (ESI-MS). Three groups of iron hydroxamate siderophores, namely the ferrioxamines, ferrichromes and coprogens/fusigens, were separated by high-performance liquid chromatography (HPLC) prior to ESI and MS2 fragmentation. For the majority of the siderophores, both protonated molecules and sodium adducts were observed. The most abundant ion was selected for collision-induced fragmentation. Potential fragmentation mechanisms are postulated and discussed. Fragmentation patterns differed between siderophore groups; however, common fragmentation patterns were observed for siderophore ions within the groups examined. Cleavage frequently occurred at carbon-nitrogen or carbon-oxygen bonds. Fragmentation of the ions also involved cleavage of iron-oxygen bonds and transfer of the charge to iron. Copyright (C) 2008 John Wiley & Sons, Lid.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available