Article
Radiology, Nuclear Medicine & Medical Imaging
Changjing Feng, Rui Chen, Siting Dong, Wei Deng, Shushen Lin, Xiaomei Zhu, Wangyan Liu, Yi Xu, Xiaohu Li, Yinsu Zhu
Summary: By analyzing clinical data and CCTA images of 400 patients, it was found that FAI and NCPB were independent risk factors for coronary plaque progression. Combining conventional parameters with radiomics features derived from CCTA can better predict plaque progression.
EUROPEAN RADIOLOGY
(2023)
Review
Medicine, General & Internal
Alyssa L. S. Chow, Saad D. Alhassani, Andrew M. Crean, Gary R. Small
Summary: The article discusses the roles of CCTA and CAC-scoring in subclinical atherosclerosis, as well as their applications in screening and guiding therapy, suggesting that CCTA plays an essential role in the detection and management of clinical coronary artery disease.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
June-sung Kim, Youn-jung Kim, Yo Sep Shin, Shin Ahn, Won Young Kim
Summary: This retrospective observational cohort study aimed to develop a prediction model for rapidly determining the occurrence of significant stenosis in coronary computed tomography angiography (CCTA) among chest pain patients without troponin elevation and ST-segment changes. A new prediction model was developed with independent associated factors for significant stenosis, and a score of >= 5 was chosen as cut-off values with 86.6% sensitivity and 56.4% specificity.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Kristian Taekker Madsen, Karsten Tange Veien, Pia Larsen, Majed Husain, Lone Deibjerg, Anders Junker, Martin Weber Kusk, Kristian Korsgaard Thomsen, Allan Rohold, Lisette Okkels Jensen, Niels Peter Ronnow Sand
Summary: This study aimed to evaluate the association between CCTA-derived FFRCT and recurrent chest pain in patients with SAP. The results showed that an abnormal FFRCT test result was associated with an increased risk of recurrent chest pain, independent of coronary calcification and stenosis. Additionally, a negative association between per-patient minimal d-FFRCT and recurrent chest pain was demonstrated, highlighting the importance of FFRCT testing in predicting long-term outcomes for patients with SAP.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Rafael Hitter, Amir Orlev, Itshak Amsalem, Nir Levi, Talya Wolak, Rivka Farkash, Naama Bogot, Michael Glikson, Arik Wolak
Summary: This study found that a high CACS is more strongly associated with severe CAD in patients with ACP compared to those with SCP. These findings suggest that CACS could impact the management of patients during the scan.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Richard D. White, Barbaros S. Erdal, Mutlu Demirer, Vikash Gupta, Matthew T. Bigelow, Engin Dikici, Sema Candemir, Mauricio S. Galizia, Jessica L. Carpenter, Thomas P. O'Donnell, Abdul H. Halabi, Luciano M. Prevedello
Summary: The study developed an artificial intelligence algorithm to assist qualified interpreting physicians in CCTA screening for total absence of coronary atherosclerosis. The algorithm demonstrated strong performance and high negative predictive values. The completion rate of the algorithm workflow process was 96% in phase 2, depending on image quality.
JOURNAL OF DIGITAL IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Ali M. Agha, Justin Pacor, Gowtham R. Grandhi, Reed Mszar, Safi U. Khan, Roosha Parikh, Tanushree Agrawal, Jeremy Burt, Ron Blankstein, Michael J. Blaha, Leslee J. Shaw, Mouaz H. Al-Mallah, Alexandria Brackett, Miguel Cainzos-Achirica, Edward J. Miller, Khurram Nasir
Summary: This study included over 92,000 patients with stable or acute CP, finding that the absence of CAC was associated with a very low prevalence of obstructive CAD, a low prevalence of nonobstructive CAD, and a low annualized risk of major adverse cardiac events, supporting the role of CAC=0 as a gatekeeper for more advanced imaging among patients presenting with CP.
JACC-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jia Zhou, Chunjie Li, Hong Zhang, Chang Liu, Junjie Yang, Jia Zhao, Yonghong Hou, Yahang Tan, Hao Wang, Yaoshuang Li, Cun Xie, Minghui Wang, Chengjian Wang, Enyuan Zhang, Shuo Wang, Pengyu Zhao, Dongkai Shan, Shuo Liang, Yufan Gao, Yong Huo, Hongliang Cong, Zhigang Guo, Yundai Chen
Summary: This study retrospectively assessed the association between the appropriateness of post-CCTA management according to CAD-RADS 2.0 and clinical outcomes. The results showed that appropriate management was associated with a lower risk of major adverse cardiovascular events and a more prudent use of invasive coronary angiography.
Article
Critical Care Medicine
Mi Lu, Fang Fang, Zhenjia Wang, Lei Xu, John E. Sanderson, Xiaojun Zhan, Lianping He, Chan Wu, Yongxiang Wei
Summary: The study found that moderate to severe OSA was associated with the presence and burden of coronary plaque, indicating an increased risk of coronary events.
Article
Cardiac & Cardiovascular Systems
Wendy S. Post, Sabina A. Haberlen, Mallory D. Witt, Long Zhang, Lisa P. Jacobson, Todd T. Brown, Joseph B. Margolick, Lawrence Kingsley, Frank J. Palella Jr., Matthew Budoff
Summary: This study reveals that the progression of coronary artery stenosis in HIV-positive individuals is associated with suboptimal HIV RNA suppression and antiretroviral therapy adherence. Effective ongoing HIV virologic suppression and adherence to antiretroviral therapy may help mitigate the risk of coronary disease events in people living with HIV.
Article
Cardiac & Cardiovascular Systems
Mohammed N. Meah, Ryan Wereski, Anda Bularga, Edwin J. R. van Beek, Marc R. Dweck, Nicholas L. Mills, David E. Newby, Damini Dey, Michelle Claire Williams, Kuan Ken Lee
Summary: In patients with acute chest pain, plasma cardiac troponin I concentrations >= 5 ng/L, even without myocardial infarction, are associated with a higher burden of low-attenuation coronary plaque. This suggests that cardiac troponin may be indicative of future adverse cardiovascular events in these patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Liu Yang, Peng Peng Xu, U. Joseph Schoepf, Christian Tesche, Balakrishnan Pillai, Rock H. Savage, Chun Xiang Tang, Fan Zhou, Hao Dong Wei, Zhong Qiang Luo, Qing Gen Wang, Chang Sheng Zhou, Meng Jie Lu, Guang Ming Lu, Long Jiang Zhang
Summary: Fractional flow reserve and plaque progression assessed by serial coronary CT angiography predicted the risk of future major adverse cardiovascular events (MACE), demonstrating better accuracy compared to traditional assessment markers.
EUROPEAN RADIOLOGY
(2021)
Article
Environmental Sciences
Manqing Luo, Xiaowei Xie, Jieyu Wu, Liwei Zhang, Xi Zheng, Mengying Xie, Na Lin, Huazhen Xiao, Jilang Zeng, Guohui Lan, Xiaoli Lu, Xiaoying Ye, Zelin Huang, Tingting Xu, Tinggui Wang, Kaiyang Lin, Yansong Guo, Xiaoxu Xie
Summary: This study investigated the association between long-term exposure to ambient particulate matter (PM10 and PM2.5) and coronary stenosis. The study found a significant correlation between chronic exposure to PM10 and PM2.5 and coronary stenosis. Each 10 μg/m3 increase in PM10 exposure was associated with a 33% increased risk of coronary stenosis, while each 10 μg/m3 increase in PM2.5 exposure was associated with an 87% increased risk. The study also identified potential mediators.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Salim A. Si-Mohamed, Sara Boccalini, Hugo Lacombe, Adja Diaw, Mohammad Varasteh, Pierre-Antoine Rodesch, Riham Dessouky, Marjorie Villien, Valerie Tatard-Leitman, Thomas Bochaton, Philippe Coulon, Yoad Yagil, Elias Lahoud, Klaus Erhard, Benjamin Riche, Eric Bonnefoy, Gilles Rioufol, Gerard Finet, Cyrille Bergerot, Loic Boussel, Joel Greffier, Philippe C. Douek
Summary: The study compared the quality of coronary CT angiography (CCTA) scans obtained with a photon-counting CT (PCCT) system and an energy-integrating dual-layer CT (DLCT) system. The results showed that PCCT provided improved image quality and diagnostic confidence compared to DLCT.
Article
Cardiac & Cardiovascular Systems
Klaske R. Siegersma, N. Charlotte Onland-Moret, Yolande Appelman, Pim van der Harst, Igor I. Tulevski, G. Aernout Somsen, Jagat Narula, Hester M. den Ruijter, Leonard Hofstra
Summary: In outpatient cardiology clinics, a CT-first strategy for patients suspected of angina pectoris was associated with reduced all-cause mortality. Patients following the CT-first strategy were more likely to receive cardiovascular preventative and antianginal medication, as well as undergo downstream diagnostics and interventions.