Review
Radiology, Nuclear Medicine & Medical Imaging
Darryl B. Sneag, Kelly C. Zochowski, Ek T. Tan
Summary: This article discusses the challenges and technical applications of using MR neurography to evaluate peripheral nerve injuries in the presence of orthopedic hardware, emphasizing the importance of real-time monitoring around metal.
Review
Radiology, Nuclear Medicine & Medical Imaging
Pietro Valerio Foti, Mario Travali, Renato Farina, Stefano Palmucci, Corrado Spatola, Luigi Raffaele, Vincenzo Salamone, Rosario Caltabiano, Giuseppe Broggi, Lidia Puzzo, Andrea Russo, Michele Reibaldi, Antonio Longo, Paolo Vigneri, Teresio Avitabile, Giovani Carlo Ettorre, Antonio Basile
Summary: Uveal melanoma is a malignant tumor originating from pigmented melanocytes, with prognosis related to histopathologic and genetic features, tumor size and location. MRI plays a key role in diagnosis and treatment planning, mainly depending on melanin content for tumor visualization. Radiologists and MRI are significant in the clinical management of uveal melanoma.
INSIGHTS INTO IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
John C. Stendahl, Jennifer M. Kwan, Darko Pucar, Mehran M. Sadeghi
Summary: The development of new radiotracers is crucial in cardiovascular medicine to address unmet diagnostic needs and support personalized therapies. This review discusses emerging radiotracers for cardiovascular imaging, covering perfusion, neuronal imaging, inflammation, fibrosis, thrombosis, calcification, and cardiac amyloidosis.
JOURNAL OF NUCLEAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hongfei Lu, Shihai Zhao, Di Tian, Shan Yang, Jianying Ma, Yinyin Chen, Meiying Ge, Mengsu Zeng, Hang Jin
Summary: Non-contrast Dixon water-fat separation CS-SENSE coronary MRA at 3.0 T can noninvasively detect clinically-relevant CAD, and sublingual NTG improves performance.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Selvadasan Vinayagamani, R. Sheelakumari, Sekar Sabarish, Santhakumar Senthilvelan, Roopa Ros, Bejoy Thomas, Chandrasekharan Kesavadas
Summary: Quantitative susceptibility mapping (QSM) is a novel MRI technique used to study magnetic susceptibility and oxygen metabolism in the brain, serving as imaging biomarkers for neurological diseases with wide clinical applications and potential.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Review
Medicine, General & Internal
Jens Kjeldsen-Kragh, Asa Hellberg
Summary: HDFN and FNAIT are two important diseases caused by maternal antibodies, and accurate determination of RhD or HPA-1a type of the fetus is crucial for their management. Noninvasive fetal RhD typing technology poses challenges but is of significant importance in providing antenatal RhD prophylaxis and determining the risk of FNAIT.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Michelle Chatwin, Ruth Helen Wakeman
Summary: The use of mechanical insufflation-exsufflation (MI-E) devices to enhance cough efficacy is on the rise. These devices are commonly used for patients with neuromuscular disorders and weak patients in acute care settings. However, there are barriers to providing MI-E, such as lack of knowledge and confidence among clinicians. Educating and building confidence in clinicians is crucial. Different approaches can be used to initiate and evaluate MI-E, including the assessment of cough peak flow (CPF). This review aims to enhance theoretical understanding and provide insights on the provision and evaluation of MI-E for clinical practice. The choice of initiation and titration methods should be based on the clinical situation, patient diagnosis (including neuromuscular disorders and beyond), and clinician's confidence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Ali Borhani, Shadi Afyouni, Mohammad Mirza Aghazadeh Attari, Alireza Mohseni, Onofrio Catalano, Ihab R. Kamel
Summary: Positron emission tomography (PET) magnetic resonance (MR) enterography is a hybrid imaging technique that combines PET imaging's metabolic information with MR imaging's spatial resolution and soft tissue contrast. It has potential roles in determining the activity status of inflammatory bowel disease (IBD), evaluating treatment response, stratifying risk, and predicting long-term clinical outcomes. However, limited studies, technical aspects, and clinical indications pose challenges in generalizing findings of this modality.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Oncology
Stanislas Quesada, Michel Fabbro, Jerome Solassol
Summary: High-grade serous ovarian cancer (HGSOC) with homologous recombination deficiency (HRD) is sensitive to PARP inhibitors (PARPi), but current methods for assessing HRD have limitations. International guidelines highlight the need for more powerful and alternative approaches to evaluate patient eligibility for PARP inhibitors.
Article
Public, Environmental & Occupational Health
Katherine J. McKay, Patricia E. Ferguson, Ramon Z. Shaban
Summary: This study explored methodological and technical considerations of using a video monitoring system (VMS) for hand hygiene auditing, highlighting concerns about privacy, security, and potential impacts on healthcare worker-patient relationships, cost-effectiveness, safety, and feedback mechanisms.
AMERICAN JOURNAL OF INFECTION CONTROL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
T. Sreelal, Anmol Bhatia, Deepti Suri, Surjit Singh, Akshay K. Saxena, Ting Y. Tao, Kushaljit Singh Sodhi
Summary: Whole-body MRI provides useful information in evaluating the extent and distribution of findings in children with JDM, with significant positive correlations with muscle enzymes and clinical examination results.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Review
Oncology
Tadeusz Robak, Pawel Robak
Summary: Hairy cell leukemia (HCL) is a rare type of chronic lymphoid leukemia diagnosed using cytology and multiparametric flow cytometry. Measurable residual disease (MRD) can help improve long-term outcomes in patients with advanced HCL.
FRONTIERS IN ONCOLOGY
(2022)
Review
Microbiology
Gina A. Suh, Thomas P. Lodise, Pranita D. Tamma, Jane M. Knisely, Jose Alexander, Saima Aslam, Karen D. Barton, Erica Bizzell, Katherine M. C. Totten, Joseph L. Campbell, Benjamin K. Chan, Scott A. Cunningham, Katherine E. Goodman, Kerryl E. Greenwood-Quaintance, Anthony D. Harris, Shayla Hesse, Anthony Maresso, Veronique Nussenblatt, David Pride, Michael J. Rybak, Zoe Sund, David van Duin, Daria Van Tyne, Robin Patel
Summary: Due to increasing antimicrobial resistance and medical device-related infections, phage therapy has gained renewed interest as an alternative or adjunct to conventional antimicrobials. However, there are significant knowledge gaps in clinical application and laboratory testing of phage therapy, leading to heterogeneity in approach and lack of consensus.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2022)
Review
Biochemistry & Molecular Biology
Jenna Turocy, Eli Y. Adashi, Dieter Egli
Summary: Our genome at conception determines much of our health as an adult, with most diseases having a heritable component that may be preventable through heritable genome editing. While preventing disease from the beginning of life is a commendable goal, there are significant hurdles that must be overcome before translating these technologies into clinical practice.
Article
Surgery
Martin Kauke, Adriana C. Panayi, Ali-Farid Safi, Valentin Haug, Bridget Perry, Branislav Kollar, Marie-Christine Nizzi, Justin Broyles, Donald J. Annino, Francisco M. Marty, Indranil Sinha, Christine G. Lian, George F. Murphy, Anil Chandraker, Bohdan Pomahac
Summary: Limited experience with facial retransplantation was reported in a patient who underwent a second transplant 88 months after irreversible allograft loss. The patient experienced chronic antibody-mediated rejection and recurrent cellular rejection prior to retransplantation, which was technically complex and required multiple arterial anastomoses. Six-month postoperative outcomes were promising, indicating that facial retransplantation is a viable option for patients with irreversible facial allograft loss.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Gastroenterology & Hepatology
Iakovos Amygdalos, Gustav Muller-Franzes, Jan Bednarsch, Zoltan Czigany, Tom Florian Ulmer, Philipp Bruners, Christiane Kuhl, Ulf Peter Neumann, Daniel Truhn, Sven Arke Lang
Summary: Machine learning algorithm can help identify high-risk patients with colorectal liver metastases (CRLM) and assess their overall survival (OS). Predictive factors based on clinicopathological characteristics include preoperative serum carcinoembryonic antigen (CEA) level, age, diameter of the largest metastasis, number of metastases, body mass index, and primary tumor grading. The application of this model can guide patient follow-up and treatment strategies.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2023)
Editorial Material
Medicine, General & Internal
Christiane K. Kuhl
Article
Radiology, Nuclear Medicine & Medical Imaging
Maike Bode, Luisa Charlotte Huck, Shuo Zhang, Teresa Nolte, Masami Yoneyama, Sven Nebelung, Christiane Katharina Kuhl
Summary: This study aimed to evaluate the effect of a cylindrical regional-suppression technique (CREST) on image quality and lesion conspicuity in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of the breast. The results showed that CREST can effectively reduce cardiac motion-related artifacts and improve image quality in breast DCE-MRI without impairing lesion conspicuity.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Correction
Multidisciplinary Sciences
Maike Bode, Shuo Zhang, Mark N. Terwolbeck, Caroline Molavi Tabrizi, Paul Sprenger, Masami Yoneyama, Nils A. Kraemer, Christiane K. Kuhl, Alexandra Barabasch
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Vincent Van den Bosch, Frederic De Beukelaer, Peter Isfort, Sebastian Keil, Christiane K. Kuhl, Philipp Bruners, Federico Pedersoli
Summary: The Long loop technique is an effective approach for repositioning dislodged catheters, especially when traditional methods are not feasible due to narrowing or thrombosis.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaofeng Jiang, Hengyu Zhao, Oliver Lester Saldanha, Sven Nebelung, Christiane Kuhl, Iakovos Amygdalos, Sven Arke Lang, Xiaojian Wu, Xiaochun Meng, Daniel Truhn, Jakob Nikolas Kather, Jia Ke
Summary: A deep learning model based on preoperative MRI scans was developed and validated to predict survival in patients with rectal cancer.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Christiane K. Kuhl
Article
Radiology, Nuclear Medicine & Medical Imaging
Timm Dirrichs, Eric Tietz, Andre Rueffer, Jens Hanten, Thai Duy Nguyen, Ebba Dethlefsen, Christiane K. Kuhl
Summary: This study compares the image quality and radiation dose of ultrahigh-pitch photon-counting CT (PCCT) with that of ultrahigh-pitch dual-source CT (DSCT) in children suspected of having congenital heart defects. The results show that PCCT offers higher signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) and better overall image quality than DSCT at a similar radiation dose.
Article
Oncology
Maike Bode, Simone Schrading, Arghavan Masoumi, Stephanie Morscheid, Sabine Schacht, Timm Dirrichs, Nadine Gaisa, Elmar Stickeler, Christiane K. Kuhl
Summary: The distinction between non-significant and significant lymph node metastases is crucial for guiding further surgical management of the axilla in women with breast cancer. This study aimed to determine the effectiveness of an abbreviated protocol for regional lymph node staging in identifying patients with significant nodal disease. The results showed that a single 3 min coronal T1-weighted sequence obtained with MRI helped rule out the presence of significant nodal disease with a high negative predictive value.
Article
Radiology, Nuclear Medicine & Medical Imaging
Christiane Kuhl, Tibor Csoszi, Wojciech Piskorski, Tomasz Miszalski, Jeong-Min Lee, Pamela M. Otto
Summary: This study compared the effectiveness of Gadopiclenol and Gadobutrol for lesion visualization in body MRI. The results showed that Gadopiclenol at a dose of 0.05 mmol/kg was comparable to Gadobutrol at a dose of 0.1 mmol/kg in terms of lesion evaluation, and both had a similar safety profile.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jens Vogel-Claussen, Torsten Gerriet Blum, Stefan Andreas, Torsten T. Bauer, Joerg Barkhausen, Volker Harth, Hans-Ulrich Kauczor, Wulf Pankow, Katrin Welcker, Rudolf Kaaks, Hans Hoffmann
Summary: The process of implementing early detection of lung cancer with LDCT in Germany has gained significant momentum. A regulation on the early detection of lung cancer is expected to come into effect by the end of 2023. In this position paper, the specialist societies involved in lung cancer screening present key points for a uniform, structured and quality-assured early detection program for lung cancer in Germany.
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Robert Siepmann, Philipp Bruners, Sven Arke Lang, Jan Bednarsch, Iakovos Amygdalos, Katharina Joechle, Federico Pedersoli, Sebastian Keil, Peter Isfort, Tom Florian Ulmer, Christiane Kuhl, Ulf Peter Neumann, Franziska Alexandra Meister, Zoltan Czigany
Summary: This study aimed to investigate the predictive role of visceral aortic calcification (VAC) in the assessment of myocardial infarction in the western European region. The results showed that VAC was associated with postoperative renal dysfunction and early allograft dysfunction, but there was no significant difference in long-term graft and patient survival.
ABDOMINAL RADIOLOGY
(2023)
Proceedings Paper
Engineering, Biomedical
Firas Khader, Christoph Haarburger, Jorg-Christian Kirr, Marcel Menke, Jakob Nikolas Kather, Johannes Stegmaier, Christiane Kuhl, Sven Nebelung, Daniel Truhn
Summary: Glaucoma is a eye disease that leads to vision loss and is usually asymptomatic until its late stages. In this study, an artificial intelligence approach based on ocular fundus images was used for glaucoma detection. By combining object detection and classification networks, a high sensitivity for glaucoma detection was achieved.
2022 IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING CHALLENGES (IEEE ISBI 2022)
(2022)
Article
Oncology
Lyn Jones, Andrea Marshall, Premkumar Elangovan, Rebecca Geach, Sadie McKeown-Keegan, Sarah Vinnicombe, Sam A. Harding, Sian Taylor-Phillips, Mark Halling-Brown, Christopher Foy, Elizabeth O'Flynn, Hesam Ghiasvand, Claire Hulme, Janet A. Dunn
Summary: The study aimed to examine the diagnostic accuracy of mammogram readers to interpret abbreviated breast MRI (abMRI) after a single day of training and compare the performance between experienced and inexperienced readers of full-protocol breast MRI (fpMRI). The results showed that inexperienced readers had lower diagnostic accuracy compared to experienced readers, suggesting the need for additional training.
BREAST CANCER RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Vincent Van den Bosch, Hizirwan Shukri Salim, Njin-Zu Chen, Otto Stroosma, Philipp Bruners, Christiane K. Kuhl, Federico Pedersoli, Peter Isfort
Summary: This study demonstrates the feasibility of a novel augmented reality system for CT-guided liver interventions. It shows that augmented reality can significantly reduce puncture time and partially improve puncture accuracy compared to free-hand interventions.
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2022)
