BMS-345541 Sensitizes MCF-7 Breast Cancer Cells to Ionizing Radiation by Selective Inhibition of Homologous Recombinational Repair of DNA Double-Strand Breaks

Transcription Factor NF-κB Inhibitors as Single Therapeutic Agents or in Combination with Classical Chemotherapeutic Agents for the Treatment of Hematologic Malignancies

(2012) Ota Fuchs   Current Molecular Pharmacology

IKKβ Regulates the Repair of DNA Double-Strand Breaks Induced by Ionizing Radiation in MCF-7 Breast Cancer Cells

(2011) Lixian Wu et al.   PLoS One

Role of SIRT1 in homologous recombination

(2010) Miriam Uhl et al.   DNA REPAIR

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA Repair Targeting and Radiotherapy: A Focus on the Therapeutic Ratio

(2010) John Thoms et al.   SEMINARS IN RADIATION ONCOLOGY

p65 Activity and ZAP-70 Status Predict the Sensitivity of Chronic Lymphocytic Leukemia Cells to the Selective I B Kinase Inhibitor BMS-345541

(2009) M. Lopez-Guerra et al.   CLINICAL CANCER RESEARCH

Periodic, Partial Inhibition of I B Kinase  -Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis

(2009) K. M. Gillooly et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2

(2009) F. Zhang et al.   MOLECULAR CANCER RESEARCH

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

(2009) Emma Bolderson et al.   NUCLEIC ACIDS RESEARCH

The NF-κB-independent functions of IKK subunits in immunity and cancer

(2009) Alain Chariot   TRENDS IN CELL BIOLOGY

Advances in Targeting IKK and IKK-Related Kinases for Cancer Therapy

(2008) D.-F. Lee et al.   CLINICAL CANCER RESEARCH

DNA repair deficiency as a therapeutic target in cancer

(2008) Sarah A Martin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Active roles for inhibitory  B kinases   and   in nuclear factor- B-mediated chemoresistance to doxorubicin

(2008) B. K. Bednarski et al.   MOLECULAR CANCER THERAPEUTICS

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics