Journal
DRUG DESIGN DEVELOPMENT AND THERAPY
Volume 9, Issue -, Pages 2079-2088Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/DDDT.S78757
Keywords
sepsis; septic shock; guidelines; critical care; biomarkers; surviving sepsis campaign
Categories
Ask authors/readers for more resources
The complexity of treating severe sepsis and septic shock has been elucidated in myriad studies, particularly in the past 10 years. The development of clinical guidelines, insight into the effect of bundle elements, and results of clinical trials have brought to light further opportunities and questions in the approach to pharmaceutical interventions for the global challenge to save lives and reduce healthcare costs. Therapeutic interventions including fluid resuscitation, hemodynamic monitoring, glycemic control, corticosteroids, and antimicrobial therapy and stewardship inform outcomes. Research on biomarkers, use of mesenchymal stem cells, blood purification, immunoglobulins, and antioxidative treatments apropos the immune response may soon yield viable therapies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available