Article
Materials Science, Multidisciplinary
Evgenii A. Ksendzov, Pavel A. Nikishau, Irina M. Zurina, Viktoria S. Presniakova, Peter Timashev, Yuri A. Rochev, Svetlana Kotova, Sergei Kostjuk
Summary: A series of well-defined macromonomers and copolymers were synthesized via ROP and RAFT-mediated copolymerization, respectively. The cloud point temperature and transition temperature of the graft copolymers showed dependence on the copolymer composition. Films prepared from these copolymers displayed better cell adhesion compared to neat PNIPAM.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Hanging Jiang, Shengda Wang, Yanhui Wang, Yaxian Wang, Liang Li, Li Ma, Dongmei Cui, Tao Tang
Summary: A new strategy has been established to access long-subchain hyper-branched polypropylene (LHB-PP) with well controlled molecular weight and topologic microstructure. Compared to linear polypropylene, the newly obtained LHB-PP solution has lower intrinsic viscosity and smaller hydrodynamic radius, while the melt exhibits higher zero shear viscosity and more apparent shear-thinning phenomenon, indicating improved properties.
Article
Polymer Science
Gabriela S. Garcia-Briones, Richard Laga, Zulfiya Cernochova, Carely Arjona-Ruiz, Olga Janouskova, Miroslav Slouf, Ognen Pop-Georgievski, Dana Kubies
Summary: Polyelectrolyte nanoparticles (NPs) have been investigated as carriers for protein delivery. The formation of these NPs was studied using a newly synthesized polycationic diblock copolymer and heparin without the use of additives. The encapsulation of heparin-binding proteins achieved high entrapment efficiency and increased protein stability. The released proteins exhibited sustained release and preserved bioactivity. The NPs showed noncytotoxic performance, making them promising candidates for controlled delivery of bioactive proteins in biomedical applications.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Hao Cai, Ping Tan, Xiaoting Chen, Michal Kopytynski, Dayi Pan, Xiuli Zheng, Lei Gu, Qiyong Gong, Xiaohe Tian, Zhongwei Gu, Hu Zhang, Rongjun Chen, Kui Luo
Summary: This study presents a smart drug-delivery system, LD-DOX/Ce6, based on LDBCs. LD-DOX/Ce6 can specifically release DOX and Ce6 in the tumor microenvironment, resulting in a synergistic chemo-photodynamic antitumor efficacy.
ADVANCED MATERIALS
(2022)
Article
Polymer Science
Shin-nosuke Nishimura, Kei Nishida, Tomoya Ueda, Shohei Shiomoto, Masaru Tanaka
Summary: Poly(N-isopropylacrylamide) (PNIPAM) is a commonly used thermoresponsive polymer that has been widely applied in biological applications. However, due to the presence of a hydrogen-bond donor, PNIPAM often induces blood clot formation, making alternatives to PNIPAM with aprotic polar functional groups necessary. In this study, acrylate polymers containing the aprotic polar functional group pyrrolidone ring were synthesized, and their lower critical solution temperatures (LCSTs) could be precisely controlled. These polymers demonstrated good blood compatibility and cell affinity, and interestingly, could activate macrophages without cytotoxicity when their hydrophobic/hydrophilic balance was altered.
Article
Pharmacology & Pharmacy
Ali Alsuraifi, Essyrose Mathew, Dimitrios A. Lamprou, Anthony Curtis, Clare Hoskins
Summary: This study successfully synthesized amphiphilic APMA monomers and copolymerized them with HPMA to form a thermoresponsive system for encapsulating and releasing model drugs. HPMAco-(APMA-Dansyl 2%) exhibited the highest drug encapsulation ability, while the incorporation of PEG resulted in faster drug release rates.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Applied
Vladimir Sincari, Svetlana Lukas Petrova, Rafal Konefal, Martin Hruby, Eliezer Jager
Summary: The study demonstrated a rapid and eco-friendly RAFT polymerization reaction of the N-(2-hydroxypropyl) methacrylamide (HPMA) monomer under microwave irradiation (MWI). By systematically investigating optimal conditions for the polymerization and utilizing different chain transfer agents, controlled living polymerization was achieved. Additionally, microwave irradiation was shown to facilitate copolymer formation, providing a convenient method for synthesizing PHPMA-based homo- and copolymers.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Polymer Science
Migle Babelyte, Laura Peciulyte, Vesta Navikaite-Snipaitiene, Joana Bendoraitiene, Volodymyr Samaryk, Ramune Rutkaite
Summary: Thermoresponsive chitosan-graft-poly(N-isopropylacrylamide) copolymers with different compositions were synthesized. The chemical structure of the copolymers was confirmed and their lower critical solution temperature (LCST) behavior was assessed. Copolymers with a certain content of poly(N-isopropylacrylamide) side chains demonstrated LCST behavior and could potentially be used in drug delivery systems or tissue engineering.
Article
Polymer Science
Krisada Auepattana-Aumrung, Treethip Phakkeeree, Daniel Crespy
Summary: Corrosion is a significant issue for metals and alloys, but can be reduced by adding corrosion inhibitors to coatings, leading to the development of polymer-corrosion inhibitor conjugates. Different fields of applications require different levels and types of metal protection, where beta-thiopropionate and ester linkages play a role in providing suitable protection for varying corrosion levels.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Alexander Plucinski, Marko Pavlovic, Mairi Clarke, David Bhella, Bernhard V. K. J. Schmidt
Summary: The study investigated the aggregation behavior of high molar mass block copolymer in an organic solvent, revealing unprecedented behavior under specific conditions. Potential future applications in photonics and templating of inorganic structures were envisioned for this new thermo-responsive block copolymer.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Polymer Science
Yoshihiko Shiraki, Masayuki Saito, Norifumi L. Yamada, Kohzo Ito, Hideaki Yokoyama
Summary: Polyolefins, the most widely used plastics globally, have poor adhesion due to the lack of polar groups, which poses challenges for recycling. In this study, a novel adhesion system using a polyurethane adhesive and an untreated polyolefin was described, where the interface is tightly bound by needle-like polyolefin crystals similar to nails adhering to wood. The polyurethane and polyolefin inter-diffuse at high temperatures, forming a mixed interfacial layer that recrystallizes upon cooling. Polyurethanes with optimally balanced non-polar and polar blocks exhibit superior adhesion due to their larger miscibility windows, polyolefin compatibilities, and the resulting long needle-like polyolefin crystals.
Article
Biochemistry & Molecular Biology
Elena Yu. Kozhunova, Anna V. Plutalova, Andrey V. Sybachin, Alexander V. Chertovich, Elena V. Chernikova
Summary: This study investigated the double stimuli-responsive properties of PNIPA and PVIM block copolymers in aqueous solutions for the first time. The synthesis of two different block copolymers was performed using RAFT polymerization. The conformational behavior and self-assembly ability of the polymers were found to depend on the location of hydrophobic groups derived from the RAFT agent within the chain, as well as the length and charge of the PVIM block.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Energy & Fuels
Radhakanta Ghosh, Janronel Pomicpic, Malcolm A. Kelland
Summary: Kinetic hydrate inhibitors (KHIs) are used to prevent gas hydrates deposition and their performance is limited by subcooling and other factors. Poly(N-isopropyl methacrylamide) (PNIPMAm) blended with triisopentylamine oxide (TiPeAO) showed exceptional KHI performance. The performance decreased at higher concentrations, possibly due to polymer and amine oxide aggregation. Overdosing of components can have detrimental effects on KHI performance.
Article
Polymer Science
Nikoletta Roka, Olga Kokkorogianni, Philippos Kontoes-Georgoudakis, Ioannis Choinopoulos, Marinos Pitsikalis
Summary: Recent advances in the controlled RAFT polymerization of complex macromolecular architectures based on PNVP are summarized in this review, with a focus on the synthesis of statistical copolymers, block copolymers, star polymers and copolymers, graft copolymers, and more complex architectures. The advantages and limitations of the synthetic methodologies are discussed in detail.
Article
Polymer Science
Yoshihiko Shiraki, Masayuki Saito, Norifumi L. Yamada, Kohzo Ito, Hideaki Yokoyama
Summary: The article describes a new adhesion system in which a polyurethane adhesive and an untreated polyolefin are tightly bound by needle-like polyolefin crystals. The polyurethane and polyolefin inter-diffuse at high temperatures to form a mixed interfacial layer, and the polyolefin recrystallizes upon cooling. Polyurethanes with optimally balanced non-polar and polar blocks exhibit superior adhesion due to their larger miscibility windows, polyolefin compatibilities, and the resulting long needle-like polyolefin crystals.
Article
Materials Science, Biomaterials
Alfonso Bayon-Fernandez, Alejandro Mendez-Ardoy, Carmen Alvarez-Lorenzo, Juan R. Granja, Javier Montenegro
Summary: This article introduces the design principles of a new family of self-assembling cyclic octapeptides that can be used as scaffolds for the development of self-healing hydrogels. By inserting different aromatic aldehyde pendants to modulate the hydrophobic/hydrophilic balance and fine-tune the properties of the resulting gel, self-healable hydrogels with viscoelastic properties can be formed.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Instruments & Instrumentation
Ana F. F. Pereira-da-Mota, Maria Vivero-Lopez, Piyush Garg, Chau-Minh Phan, Angel Concheiro, Lyndon Jones, Carmen Alvarez-Lorenzo
Summary: This study aimed to evaluate the release profiles of two drug-loaded contact lenses (CLs) in a 3D in vitro eye blink model and compare them with in vivo profiles. The results showed that the release of both drugs was more sustained and lower in the 3D eye model compared to in vitro release in vials. The findings suggest that the current 3D printed eye blink model could be a useful tool to measure the release of ophthalmic drugs from medicated CLs, but further optimization is needed.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Materials Science, Paper & Wood
G. G. Flores-Rojas, E. Vazquez, F. Lopez-Saucedo, L. Buendia-Gonzalez, R. Vera-Graziano, E. Mendizabal, E. Bucio
Summary: Controlled synthesis of pH-responsive biomaterials by radiation chemistry enables the development of affordable materials with finely-tuned properties and without potentially harmful chemicals. In this study, a radiation-grafting-induced technique was used to attach 4-vinylpyridine (4VP) onto a lignocellulosic membrane, resulting in pH-responsive lignocellulose-based materials with antimicrobial properties for wound dressing. These materials exhibited improved drug load and prolonged release of an antimicrobial glycopeptide drug. Additionally, they demonstrated excellent antimicrobial activity against Gram-positive bacteria at different pH levels. Various characterization techniques were employed to evaluate the new materials, including thermogravimetric analysis, contact angle measurements, scanning electron microscopy, infrared spectroscopy, mechanical testing, nuclear magnetic resonance, X-ray photoelectron spectroscopy, and microbiological tests.
Article
Pharmacology & Pharmacy
Carmen Alvarez-Lorenzo, Maria Vivero-Lopez, Angel Concheiro
Summary: This study demonstrates the spontaneous formation of anisotropic gold nanoparticles (AuNPs) inside preformed contact lenses (CLs) without the need for additional reductant agents. The formation of AuNPs was achieved through a precise tuning of the monomeric composition, saline concentration, and the use of steam heat sterilization. The potential applications of incorporating AuNPs in CLs in the ocular field for prophylaxis, therapy, and diagnosis are highlighted. The developed CLs also exhibit photoresponsiveness and efficient filtering of highly penetrant light.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Pharmacology & Pharmacy
Carmela Tommasino, Giulia Auriemma, Carla Sardo, Carmen Alvarez-Lorenzo, Emilia Garofalo, Silvana Morello, Giovanni Falcone, Rita P. Aquino
Summary: In this study, a PCL/INU-PLA hybrid biomaterial was prepared, which showed improved surface properties, swelling ability, and in vitro biodegradation rate compared to PCL alone. The 3D printed scaffolds exhibited dimensional and structural parameters close to the digital model and showed favorable results in biocompatibility and osteogenic activity tests.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Polymer Science
Kathleen Abigail Montoya-Villegas, Mirian Angelene Gonzalez-Ayon, Carmen Alvarez-Lorenzo, Angel Licea-Claverie, Emilio Bucio, Alejandro Ramirez-Jimenez
Summary: Thermo-responsive, hydrophilic, hemo- and biocompatible poly(DEGMA-co-OEGMA) was grafted onto silicone rubber using the gamma-radiation pre-irradiation method. The size of the grafted chains was controlled using a RAFT agent. The grafted materials showed enhanced hydrophilicity and excellent hemo- and cytocompatibility, indicating potential applications in the biomedical field.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Polymer Science
Felipe Lopez-Saucedo, Leticia Buendia-Gonzalez, Hector Magana, Guadalupe Gabriel Flores-Rojas, Emilio Bucio
Summary: This study proposes the development of an affordable polymer film for healthcare purposes. The film consists of chitosan, itaconic acid, and Randia capitata fruit extract. The film is formed through crosslinking of chitosan with itaconic acid and in situ addition of R. capitata fruit extract. The resulting ionically crosslinked composite film shows promising potential as a wound dressing due to the combined properties of chitosan and R. capitata fruit extract in supporting epithelial regeneration.
Article
Pharmacology & Pharmacy
Axel Kattar, Ana Quelle-Regaldie, Laura Sanchez, Angel Concheiro, Carmen Alvarez-Lorenzo
Summary: The aim of this study was to develop cationic niosomes for the ocular delivery of epalrestat, a drug used in the treatment of diabetic eye damage. The niosomes were characterized and found to have a size of 80 nm, a charge ranging from -23 to +40 mV, and a spherical shape. The encapsulation efficiency of the niosomes was 99.76% and they showed a sustained release of the drug over 20 days. The niosomes were non-irritating, non-toxic, and showed higher permeation in the sclera compared to the unencapsulated drug.
Review
Engineering, Biomedical
Mariana Zarur, Alejandro Seijo-Rabina, Alvaro Goyanes, Angel Concheiro, Carmen Alvarez-Lorenzo
Summary: This review focuses on the recent advances in pH-responsive polymer-based scaffolds that have been demonstrated in vivo to be suitable for wound and bone healing. pH plays a critical role in the tissue regeneration process, and small changes can significantly impact the healing process. Various strategies, including changes in ionization of natural polymers, ionizable monomers and clays, reversible cross-linkers, coatings, and production of CO2 gas, have been tested to prepare pH-responsive scaffolds. These techniques have shown promise in achieving biocompatible and environment-friendly scaffolds that can be translated to clinical applications.
ACTA BIOMATERIALIA
(2023)
Review
Biochemistry & Molecular Biology
Federica Ragucci, Francesca Sireci, Francesco Cavallieri, Jessica Rossi, Giuseppe Biagini, Giovanni Tosi, Chiara Lucchi, Rodolfo Molina-Pena, Natalia Helen Ferreira, Mariana Zarur, Alba Ferreiros, William Bourgeois, Francois Berger, Miguel Abal, Audrey Rousseau, Frank Boury, Carmen Alvarez-Lorenzo, Emmanuel Garcion, Anna Pisanello, Giacomo Pavesi, Corrado Iaccarino, Luca Ghirotto, Maria Chiara Bassi, Franco Valzania
Summary: Nanotechnology shows promise in cancer treatment, particularly in the field of neuro-oncology. It is important to explore clinicians' intentions and perspectives on using this new technology in clinical practice.
Article
Engineering, Biomedical
Carmen Alvarez-Lorenzo, Mariana Zarur, Alejandro Seijo-Rabina, Barbara Blanco-Fernandez, Isabel Rodriguez-Moldes, Angel Concheiro
Summary: The imbalance between life expectancy and quality of life is increasing due to the raising prevalence of chronic diseases. Scaffolds that can mimic natural physical stimuli and deliver dynamic physical stimuli, such as electrical signals, have shown potential for more efficient tissue regeneration.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Physical
A. Khallouqi, A. Halimi, O. El Rhazouani
Summary: A pediatric head phantom made of epoxy resin was used to evaluate radiation exposure in CT scans. The phantom demonstrated dosimetric properties comparable to commercially available phantoms, making it a practical and economical option for assessing radiation dose in children.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
M. Y. Shoeib, Doaa A. Ahmed, A. F. Abd-Elraheem
Summary: The research aims to measure and analyze the levels of radon concentration, radium concentration, and radon exhalation rates in geopolymer cement mixes, and assess their impact on indoor air quality. Results indicate that geopolymer cement materials are safe for use in construction, except for specific mixes.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
M. J. Leotlela
Summary: This article presents the results of radiochemical events/processes that occur when water is exposed to ionising radiation of charged particles (beta and alpha-particles). The idea of cogeneration becomes even more lucrative if we consider that hydrogen energy generation is clean (also known as green energy) because of its insignificant contribution to environmental pollution. These results supplement the fluctuation in effective dose theory/hypothesis of a previous study on time-dependent variations in the radiological health impact of an interim SNFS facility presented in 2021 (Leotlela, 2021).
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Vyacheslav Ivanovich Pavlenko, Roman Vladimirovich Sidelnikov, Vitaly Valerievich Kashibadze, Mikhail Igorevich Dobynde, Dmitry Alexandrovich Kartashov, Vyacheslav Alexandrovich Shurshakov
Summary: This work explores the possibility of using a polymer composite to protect against neutron radiation in space conditions. The study shows that the proposed polymer composite has high structural properties necessary for use in space. Monte Carlo simulation is used to evaluate the neutron radiation passage through the material. The results demonstrate that the protective layer made of the polymer composite is thinner and more suitable for spacecraft, which is crucial due to limited space on board.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Islam G. Alhindawy, M. I. Sayyed, Dalal Abdullah Aloraini, Aljawhara H. Almuqrin, Mohammad S. Alomar, Gaber A. Elawadi, K. A. Mahmoud
Summary: This study investigated the effects of Neodymium (III) nitrate hexahydrate and lanthanum nitrate hexahydrate on the structural and radiation shielding properties of zircon mineral, and a new La/Nb-doped ZrO2 nanocomposite was fabricated. Experimental techniques such as energy-dispersive X-ray, scanning electron microscope, transmission electron microscopy, and X-ray diffraction pattern were used to analyze the structure and composition of the fabricated nanocomposites. Monte Carlo simulation was employed to evaluate the gamma-ray shielding properties. The results showed that the fabricated composites had good shielding characteristics, with a shielding capacity of 30-50% compared to pure lead in the intermediate energy range of 0.244-2.506 MeV.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Hassan Salah, Mohammed Alkhorayef, Layal Jambi, Mohammed Almuwanis, Abdelmoneim Sulieman
Summary: Cardiovascular nuclear medicine imaging examinations expose patients to high doses of ionizing radiation. This study assessed the radiation doses and public exposure in cardiac rest and stress SPECT scans. The effective dose from cardiac stress was higher than previous studies, which may be influenced by clinical indication imaging protocols and radiation safety measures.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Leandro Barbosa da Silveira Gatto, Delson Braz, Leonardo Pacifico, Paulo Travassos, Luis Alexandre Goncalves Magalhaes
Summary: This study evaluated the mean glandular dose (MGD) in mammography using a computed radiography (CR) system with a solid-state detector. Irradiations and simulations were conducted to determine the MGD and spectra for the same conditions. The results showed that the glandular dose was below the acceptable levels and the spectra were mostly in accordance with the literature.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Mawya Khafaji, Rashid Barnawi, Salma Amoudi, Hassan Gabbani, Rayan Alhazmi, Rayan Ahyad, Khalid Alsafi, Khuld Saeedi, Hassan Salah, Nissren Tamam, David Bradley, Sarah Albahiti, Abdelmoneim Sulieman
Summary: This study aimed to calculate typical values for common pediatric studies at King Abdulaziz University Hospital and compare them with other studies. The results showed that radiation dose levels in pediatric CT examinations were generally lower compared to other studies.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Faisal Almisned, Iskender Akkurt, Nurdan Karpuz
Summary: In this study, cross sections of medical radioisotopes were calculated using level density models. The results were compared with experimental data and it was found that the GSM level density models generally yielded consistent conclusions.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Shokufeh Saeid, Neda Mollakhalili-meybodi, Fateme Akrami Mohajeri, Farzan Madadizadeh, Elham Khalili Sadrabad
Summary: This study found that gamma irradiation significantly reduces the saponin and phytic acid content of quinoa. At a dose of 2.5 kGy, it can effectively reduce saponin and phytic acid without significantly damaging the antioxidant compounds.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Maria Demeter, Ion Calina, Anca Scarisoreanu, Valentina Mitran, Marcela Popa, Anisoara Cimpean, Mariana Carmen Chifiriuc, Marin Micutz, Elena Matei, Bogdana Mitu
Summary: Novel biocompatible composite hydrogels with good elastic and antimicrobial properties were synthesized by e-beam cross-linking using chitosan, water-soluble polymers, and silver nanoparticles (AgNP). The composite hydrogels showed high stability, absorption capability specific to infected wounds, and biocompatibility. The antimicrobial activity was influenced by the amount of AgNP and cross-linking degree, with significant inhibition against Gram-negative bacteria.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Anuor AT. Ayoub, Yushou Song, Mamoun IA. Sagiroun
Summary: This paper presents an assessment of the radiological hazard for humans from nuclear power plant effluent released into a river under normal operation scenarios. The study concludes that the radiological hazard from this effluent is minimal and within acceptable limits according to international standards. It also highlights the potential hazards related to the higher concentration of 137Cs in sediments over time.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Irabati Chakraborty, Nidhi Sinha, Bobby Antony
Summary: This article investigates the electron impact ionization of prebiotic molecules within the interstellar medium. By calculating the electron impact ionization cross section, the study provides insights into the chemistry of these molecules and their interaction with electrons, which play a vital role in the emergence of life's essential building blocks.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
C. V. Vishnu, Antony Joseph
Summary: This study investigated the gamma-ray shielding properties of composite materials made from natural rubber with different proportions of Barium Tungstate. The addition of Barium Tungstate significantly improved the characteristics of gamma radiation shielding. The experimental measurements showed good agreement with theoretical calculations obtained from simulation results.
RADIATION PHYSICS AND CHEMISTRY
(2024)
Article
Chemistry, Physical
Derya Mutlu, Idris Karagoz, Harun Sepetcioglu, Urkiye Akar Tarim, Orhan Gurler
Summary: This study examined the properties of epoxy composites with dendritic copper particles and found that the addition of copper particles improved the electrical conductivity and mechanical properties of the composites. The glass transition temperature of the composites could be adjusted by varying the copper particle ratio. The study also evaluated the shielding properties of epoxy-based composites against gamma radiation and found that the addition of copper particles significantly altered the microstructure and mechanical properties of the composites.
RADIATION PHYSICS AND CHEMISTRY
(2024)