High glucose induces and activates Toll-like receptor 4 in endothelial cells of diabetic retinopathy

Intermittent High Glucose Implements Stress-Induced Senescence in Human Vascular Endothelial Cells: Role of Superoxide Production by NADPH Oxidase

(2015) Morihiko Maeda et al.   PLoS One

Hyperglycemia Induces Toll-Like Receptor-2 and -4 Expression and Activity in Human Microvascular Retinal Endothelial Cells: Implications for Diabetic Retinopathy

(2015) Uthra Rajamani et al.   Journal of Diabetes Research

Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats

(2014) Yan-Ling Wang et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

High-mobility group box-1 and its role in angiogenesis

(2014) S. Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Role of TLR2 and 4-Mediated Inflammatory Pathways in Endothelial Cells Exposed to High Glucose

(2014) Harshini Mudaliar et al.   PLoS One

Constant or fluctuating hyperglycemias increases cytomembrane stiffness of human umbilical vein endothelial cells in culture: roles of cytoskeletal rearrangement and nitric oxide synthesis

(2013) Xianxian Chen et al.   BMC CELL BIOLOGY

TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes

(2012) Baojun Dong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Toll-Like Receptor 4 Activation in Microvascular Endothelial Cells Triggers a Robust Inflammatory Response and Cross Talk With Mononuclear Cells via Interleukin-6

(2012) Zhongyang Lu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Angiogenesis Mediated by Toll-Like Receptor 4 in Ischemic Neural Tissue

(2012) Chang He et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased Toll-Like Receptor Activity in Patients With Metabolic Syndrome

(2012) I. Jialal et al.   DIABETES CARE

High glucose increases nitric oxide generation in lipopolysaccharide-activated macrophages by enhancing activity of protein kinase C-α/δ and NF-κB

(2012) Kuo-Feng Hua et al.   INFLAMMATION RESEARCH

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Role of the retinal vascular endothelial cell in ocular disease

(2012) Arpita S. Bharadwaj et al.   PROGRESS IN RETINAL AND EYE RESEARCH

High-Mobility Group Box-1 Mediates Toll-Like Receptor 4–Dependent Angiogenesis

(2011) Qing Lin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy

(2011) M. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

(2010) Mohan R. Dasu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications

(2010) Sridevi Devaraj et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Targeting HMGB1 in inflammation

(2009) Huan Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy

(2009) Ling Zheng   Frontiers in Bioscience-Landmark

Toll-like receptor 4 gene polymorphism and early onset of diabetic retinopathy in patients with type 2 diabetes

(2009) Monika Buraczynska et al.   HUMAN IMMUNOLOGY

High Glucose Induces Toll-Like Receptor Expression in Human Monocytes: Mechanism of Activation

(2008) M. R. Dasu et al.   DIABETES

Human C-peptide antagonises high glucose-induced endothelial dysfunction through the nuclear factor-κB pathway

(2008) P. Luppi et al.   DIABETOLOGIA

Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State

(2007) Sridevi Devaraj et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM