Journal
QUIMICA NOVA
Volume 34, Issue 10, Pages 1762-1769Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0100-40422011001000009
Keywords
solid lipid nanoparticle; production of methods; technological parameters
Categories
Ask authors/readers for more resources
SOLID LIPID NANOPARTICLES: CLASSICAL METHODS OF LAB PRODUCTION. Solid lipid nanoparticles have been extensively investigated as drug delivery systems. These colloidal systems have major advantages compared to others more traditional. Reported advantages include sustained release, ability to solubilize lipophilic drugs, increased physical and chemical stability of labile molecules, decreased unwanted side-effects showing lower toxicity, and scale up facilities. This paper aims at reviewing the traditional methods of solid lipid nanoparticles production, such as fusion-emulsification (hot and cold), solvent evaporation-emulsification and microemulsion, dealing with the main technological parameters that influence the quality properties of solid lipid nanoparticles.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available