Review
Public, Environmental & Occupational Health
Rebecca J. Jarden, Richard J. Siegert, Jane Koziol-McLain, Helena Bujalka, Margaret H. Sandham
Summary: This systematic review examines the validity and reliability of existing worker wellbeing measures developed between 2010 to 2020. The review found that few worker wellbeing measures met the criteria for validity and reliability. The study recommends researchers and clinicians to carefully consider the selection of worker wellbeing measures.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Psychology, Multidisciplinary
Danilo Garcia, Maryam Kazemitabar, Mojtaba Habibi Asgarabad
Summary: Psychological wellbeing plays a vital role in our ability to cope with and thrive in the challenges of life. The measurement of psychological wellbeing is important for identifying mental illness and promoting health. This study examined the psychometric properties of the 18-item Swedish version of Ryff's Psychological Wellbeing Scale and found that a five-factor model provided a better fit than the original six-factor model. The scale demonstrated good internal consistency and concurrent validity, and measurement precision was similar across gender. Some items may need revision to improve accuracy.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Bianca Nubia Souza Silva, Bianca Gonzalez Martins, Lucas Arrais Campos, Joao Maroco, Juliana Alvares Duarte Bonini Campos
Summary: The study aimed to evaluate the psychometric properties of the Autoquestionnaire Qualite de Vie Enfant Image (AUQEI) in pre-school children and determine the influence of demographic characteristics on their subjective wellbeing. Construct validity was assessed using confirmatory analysis, while reliability was measured by the ordinal alpha and omega coefficients. The results showed that the single-factor AUQEI model provided valid, reliable, and invariant results, making it a relevant and interesting instrument for assessing wellbeing in young children.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Psychology, Multidisciplinary
Qurat ul Ain, Ling Xie, Tahir Yousaf
Summary: This article contributes to the limited empirical literature by investigating the impact of decentralization on psychological wellbeing. The study finds that fiscal decentralization in the healthcare sector in Pakistan has a substantial and positive influence on the effectiveness of public policy in improving healthcare outcomes.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Medicine, General & Internal
Jacco J. A. S. Smeets, Kim Rijkers, Linda Ackermans, Olaf Schijns, Ghislaine A. P. G. van Mastrigt, Rob Rouhl, G. Louis Wagner, Sander van Kuijk, Jeske Nelissen, Ilse E. C. W. van Straaten, Kuan Kho, Francesca Snoeijen-Schouwenaars, Anne-Marthe Meppelink, Sylvia Klinkenberg, H. J. M. Majoie
Summary: Epilepsy is a common neurological disorder, and neuromodulation can be an option for drug-resistant patients. This study aims to determine the change in quality of life after neuromodulation and study the cost-effectiveness of these treatments.
Article
Oncology
Joseph Lipscomb, Susan Horton, Albert Kuo, Cristian Tomasetti
Summary: Emerging data suggests that a single, minimally invasive liquid biopsy test could be used on a broad scale to screen individuals for multiple types of cancer while minimizing false-positive results. Decision modeling can be used to study the health and economic consequences of such testing in at-risk populations. Small-scale analyses involving hypothetical cancers demonstrate the cost-effectiveness of MCED testing and highlight the importance of test-induced stage shift. Further prospective investigations are needed to evaluate the clinical value, benefits, risks, and overall impact of MCED testing on health outcomes and costs.
Article
Neurosciences
Ataru Igarashi, Yukinori Sakata, Mie Azuma-Kasai, Harue Kamiyama, Mika Kawaguchi, Kiyoyuki Tomita, Mika Ishii, Manabu Ikeda
Summary: In order to meet the increasing need in Japan, a cognition bolt-on version of the EQ-5D-5L (EQ-5D-5L+C) was developed and linguistically and psychometrically validated. The validated proxy version of EQ-5D-5L+C is a valid tool for assessing health status, including cognitive function, and allows for longitudinal assessment.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Health Care Sciences & Services
Allison Shapiro, Benjamin Bradshaw, Sabine Landes, Petra Kammann, Beatrice Bois De Fer, Wei-Nchih Lee, Robert Lange
Summary: This study utilized digital devices to collect data on the daily symptoms and medication management of constipation patients. The results showed that constipation status was associated with activity metrics (such as steps, sleep), and the likelihood of medication treatment increased as symptom severity increased.
NPJ DIGITAL MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Pablo A. Gonzalez, Francisca Dussaillant, Esteban Calvo
Summary: This study explores the multidimensional relationships between capabilities, subjective wellbeing, and social belongingness, finding that certain capabilities are closely correlated with individual and social subjective wellbeing, while others show correlations only when measured as functionings. The findings highlight the complexity and non-linearity of the relationships between capabilities and subjective wellbeing, underscoring the importance of considering both subjective and objective, as well as individual and social aspects.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Oncology
Emily E. van Seventer, Madeleine G. Fish, Kathryn Fosbenner, Katie Kanter, Amirkasra Mojtahed, Jill N. Allen, Lawrence Blaszkowsky, Jeffrey W. Clark, Jon Dubois, Joseph W. Franses, Bruce J. Giantonio, Lipika Goyal, Samuel J. Klempner, Eric J. Roeland, David P. Ryan, Colin D. Weekes, Therese Mulvey, Areej El-Jawahri, Nora Horick, Ryan B. Corcoran, Aparna R. Parikh, Ryan D. Nipp
Summary: This study found that baseline patient-reported outcomes (PROs) are associated with treatment response, healthcare utilization, and survival in patients with advanced gastrointestinal cancer. Specifically, physical symptoms and functional quality of life were correlated with disease progression and survival.
Article
Medicine, General & Internal
Emily Herrett, Keith Tomlin, Liang-Yu Lin, Laurie A. Tomlinson, Mark Jit, Andrew Briggs, Michael Marks, Frank Sandmann, John Parry, Christopher Bates, Jessica Morley, Seb Bacon, Benjamin Butler-Cole, Viyaasan Mahalingasivam, Alan Dennison, Deb Smith, Ethan Gabriel, Amir Mehrkar, Ben Goldacre, Liam Smeeth, Rosalind M. M. Eggo
Summary: This study aims to understand the impact of long COVID on health-related quality of life and productivity in English primary care patients. Participants will be asked to complete questionnaires through a smartphone app, covering aspects such as HRQoL, productivity, and symptoms of long COVID. Analysis will be conducted using the OpenSAFELY data platform to estimate the impact on HRQoL, productivity, and cost to the NHS.
Review
Development Studies
Kate Sollis, Mandy Yap, Paul Campbell, Nicholas Biddle
Summary: There is a growing movement worldwide to utilize wellbeing measures more effectively in policy-making. This is driven by the recognition that economic indicators alone may not adequately capture the aspects of life that are valued by individuals. Participatory wellbeing frameworks, created through collaboration with the relevant population and asking them what wellbeing means to them, have been found to be valuable. However, there is currently limited understanding of the work conducted in this area. This systematic review aims to fill this gap by identifying 130 participatory wellbeing studies from around the world and analyzing their methods and findings.
Article
Economics
Tessa Peasgood, Clara Mukuria, John Brazier, Ole Marten, Simone Kreimeier, Nan Luo, Brendan Mulhern, Wolfgang Greiner, A. Simon Pickard, Federico Augustovski, Lidia Engel, Luz Gibbons, Zhihao Yang, Andrea L. Monteiro, Maja Kuharic, Maria Belizan, Jakob Bjorner
Summary: This study explored the psychometric performance of candidate items for the EQ-HWB measure. The results showed that the items had good discrimination ability in groups with known health conditions, but lower discrimination ability in carers. Factor analysis and IRT provided valuable insights for item selection.
Review
Clinical Neurology
Anne Kitschen, Milda Aleknonyte-Resch, Gabija Sakalyte, Freya Diederich
Summary: This systematic review aims to evaluate the cost-effectiveness of surgical treatment compared to medical treatment for drug-refractory epilepsy patients. The findings suggest that surgical treatment is more cost-effective, especially when considering a long-term perspective.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Clinical Neurology
Anne Kitschen, Milda Aleknonyte-Resch, Gabija Sakalyte, Freya Diederich
Summary: Surgical treatment is cost-effective compared to medical treatment for patients with drug-refractory epilepsy, especially when considering a lifetime perspective. All disease-specific costs should be taken into account when assessing the cost-effectiveness of epilepsy treatment.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Ophthalmology
Jan Henrik Terheyden, Susanne G. Pondorfer, Charlotte Behning, Moritz Berger, Jill Carlton, Donna Rowen, Christine Bouchet, Stephen Poor, Ulrich F. O. Luhmann, Sergio Leal, Frank G. Holz, Thomas Butt, John E. Brazier, Robert P. Finger
Summary: This study aims to validate the Vision Impairment in Low Luminance (VILL) questionnaire for assessing visual functioning and vision-related quality of life (VRQoL) in patients with age-related macular degeneration (AMD) under low luminance, low-contrast conditions. The VILL questionnaire was translated into multiple languages and analyzed using Rasch analysis. The results supported the reliability and validity of the shortened version of the questionnaire, VILL-33, across all stages of AMD.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Public Administration
Catherine Needham, Kerry Allen, Emily Burn, Kelly Hall, Catherine Mangan, Hareth Al-Janabi, Warda Tahir, Sarah Carr, Jon Glasby, Melanie Henwood, Steve Mckay
Summary: The Care Act 2014 empowered English local authorities to shape social care markets and collaborate with stakeholders. Different types of market shaping are being utilized in different parts of the care market, but sustainability challenges are pulling authorities towards approaches that emphasize strong rules.
JOURNAL OF SOCIAL POLICY
(2023)
Article
Economics
Paul Mark Mitchell, Rachael L. Morton, Mickael Hiligsmann, Samantha Husbands, Joanna Coast
Summary: Substantial losses in capability wellbeing were observed during the first year of the COVID-19 pandemic in the UK, Australia, and the Netherlands. Future research is needed to understand the specific impact of different COVID-19 restrictions on individuals' capabilities.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Pediatrics
Hannah B. Edwards, Maria Theresa Redaniel, Carlos Sillero-Rejon, Ruta Margelyte, Tim J. Peters, Kate Tilling, William Hollingworth, Hugh McLeod, Pippa Craggs, Elizabeth Hill, Sabi Redwood, Jenny Donovan, Emma Treloar, Ellie Wetz, Natasha Swinscoe, Gary A. Ford, John Macleod, Karen Luyt
Summary: This study evaluated the effectiveness and cost-effectiveness of the National PReCePT Programme in increasing the use of magnesium sulfate in preterm births. The results showed that the implementation of the NPP significantly increased the uptake of magnesium sulfate in preterm births in 137 maternity units in England. From a societal and lifetime perspective, the NPP generated health gains and cost savings, making it a cost-effective intervention.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Endocrinology & Metabolism
Jill Carlton, Philip Powell, Donna Rowen, Melanie Broadley, Frans Pouwer, Jane Speight, Simon Heller, Mari-Anne Gall, Myriam Rosilio, Christopher J. Child, Jonathan Comins, Rory J. McCrimmon, Bastiaan de Galan, John Brazier
Summary: This study aims to develop a new hypoglycaemia-specific PROM to assess the impact of hypoglycaemia on quality of life in patients with diabetes. The study uses a mixed-methods, three-stage design, collecting information through qualitative interviews and validating it through psychometric testing, ultimately generating a hypoglycaemia-specific PROM and preference-based measure.
Article
Health Care Sciences & Services
Philip A. Powell, Milad Karimi, Donna Rowen, Nancy Devlin, Ben van Hout, John E. Brazier
Summary: This study explores the public understanding, opinions, and potential solutions to differences between hypothetical and experienced responses in the context of health resource allocation. Most participants found it difficult to imagine health states without experience, and favored experienced responses as more accurate. The study suggests recruiting people with greater experience or incorporating other views as acceptable solutions.
QUALITY OF LIFE RESEARCH
(2023)
Article
Economics
Sarah Acaster, Clara Mukuria, Donna Rowen, John E. Brazier, Claire E. Wainwright, Bradley S. Quon, Jamie Duckers, Alexandra L. Quittner, Yiyue Lou, Patrick R. Sosnay, Lisa J. McGarry
Summary: This study developed a preference-based utility measure for cystic fibrosis (CF) based on the CFQ-R questionnaire, which is the first disease-specific scoring algorithm for CF. It allows for estimation of disease-specific utilities and can be used in cost-effectiveness analysis.
Article
Medicine, General & Internal
F. C. C. Hamdy, J. L. L. Donovan, J. A. Lane, C. Metcalfe, M. Davis, E. L. L. Turner, R. M. M. Martin, G. J. J. Young, E. I. I. Walsh, R. J. J. Bryant, P. Bollina, A. Doble, A. Doherty, D. Gillatt, V Gnanapragasam, O. Hughes, R. Kockelbergh, H. Kynaston, A. Paul, E. Paez, P. Powell, D. J. J. Rosario, E. Rowe, M. Mason, J. W. F. Catto, T. J. J. Peters, J. Oxley, N. J. J. Williams, J. Staffurth, D. E. E. Neal
Summary: A study in the UK showed that after 15 years of follow-up, the mortality rate of prostate cancer was low regardless of the treatment assigned. Therefore, the choice of therapy for localized prostate cancer involves considering the trade-offs between benefits and harms.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, Research & Experimental
Debbie Tallon, Laura Thomas, Sally Brabyn, Brian Chi Fung Ching, Jane Sungmin Hahn, Berry Jude, Mekeda Logan, Alex Burrage, Fiona Fox, Simon Gilbody, Paul Lanham, Glyn Lewis, Jinshuo Li, Stephanie J. MacNeill, Irwin Nazareth, Steve Parrott, Tim J. Peters, Roz Shafran, Katrina Turner, Chris Williams, David Kessler, Nicola Wiles
Summary: The INTERACT trial will evaluate the clinical and cost-effectiveness, as well as the acceptability to therapists and clients, of the integration of online CBT materials and high-intensity therapist-led CBT delivered remotely. If successful, this model could increase access to and equity of CBT provision.
Article
Economics
Chris Skedgel, Patricia Cubi-Molla, David Mott, Sofia Gameiro, Jacky Boivin, Hareth Al-Janabi, John Brazier, Marie Markert, Fredrik L. Andersson, Mireia Jofre-Bonet
Summary: An increasing number of prospective parents are facing infertility issues and experiencing negative impacts on mental health and life satisfaction. The value of assistive reproductive technologies (ART) in achieving parenthood goals needs to be understood beyond health-related quality of life (HRQOL) and cost per live birth. A broader perspective on wellbeing and societal impact is necessary to assess the full range of negative and positive impacts associated with unmet parenthood goals and successful ART.
PHARMACOECONOMICS-OPEN
(2023)
Article
Obstetrics & Gynecology
Hannah B. Edwards, Maria Theresa Redaniel, Carlos Sillero-Rejon, Christalla Pithara-McKeown, Ruta Margelyte, Tracey Stone, Tim J. Peters, William Hollingworth, Hugh Mcleod, Pippa Craggs, Elizabeth M. Hill, Sabi Redwood, Emma Treloar, Jenny L. Donovan, Brent C. Opmeer, Karen Luyt
Summary: This study compared two quality improvement interventions to improve the uptake of antenatal magnesium sulphate (MgSO4) in preterm births for the prevention of cerebral palsy. The results showed that enhanced support did not further improve MgSO4 uptake but may improve teamwork. Therefore, further research is needed to explore targeted enhanced support, sustainability of improvements, and the possible indirect benefits of stronger teamwork associated with enhanced support.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Economics
David J. Mott, Hannah Schirrmacher, Hareth Al-Janabi, Sophie Guest, Becky Pennington, Nicolas Scheuer, Koonal K. Shah, Chris Skedgel
Summary: The provision of unpaid care can have significant effects on carers, impacting their quality of life and influencing the evaluation of new technologies. Considering these effects in health economic models, particularly the quality of life of carers, can greatly affect cost effectiveness calculations. However, this may lead to situations where life-extending treatments for patients are considered cost ineffective due to their impact on carer quality of life. This highlights the need for careful consideration and potential solutions in health technology assessment.
Article
Medicine, Research & Experimental
Karen Morgan, Mei-See Man, Rachael Bloomer, Madeleine Cochrane, Melissa Cole, Sandi Dheensa, Nathan Eisenstadt, Gene Feder, Daisy M. Gaunt, Rwth Leach, Rebecca Kandiyali, Sian Noble, Tim J. Peters, Beverly A. Shirkey, Helen Cramer
Summary: This study aims to estimate the effectiveness and cost-effectiveness of a perpetrator programme for men.
Article
Psychiatry
Darragh Glavin, Eoin Martino Grua, Carina Akemi Nakamura, Marcia Scazufca, Edinilza Ribeiro dos Santos, Gloria H. Y. Wong, William Hollingworth, Tim J. Peters, Ricardo Araya, Pepijn Van de Ven
Summary: This study used machine learning and PHQ-9 items to identify the most predictive ultrabrief questionnaire for depressive symptomatology and validated its use with external data sets. The study found that alternative PHQ-9 item pairings were more effective than the PHQ-2 for prescreening depressive symptomatology.
JMIR MENTAL HEALTH
(2023)
Article
Economics
Carol McLoughlin, Ilias Goranitis, Hareth Al-Janabi
Summary: The objective of this study was to qualitatively assess the feasibility, content validity, and acceptability of 5 QoL measures with informal carers. The study found that these measures had low error rates and were considered concise, clear, and relevant by most carers. Challenges included relevance, context, and time period. The study also found that informal carers generally preferred using care-related QoL measures.
