Article
Psychiatry
Karolina Kossakowska, Eleonora Bielawska-Batorowicz
Summary: This study aimed to identify the predictors of postpartum depression for different feeding methods (breastfeeding, mixed-feeding, formula-feeding). The results showed that women in different feeding groups differed in stress, bonding difficulties, and beliefs related to feeding practices. The best predictors of depressive symptoms for breastfeeding women included maternal satisfaction, intrapsychic stress, and concerns about feeding on a schedule; for mixed-feeding women - emotional tension, concern about infant's hunger, overeating, and awareness of infant's hunger and satiety cues; and for formula-feeding women, predictors included emotional tension, bonding difficulties, and maternal feeding practices and beliefs related to concerns about undereating, awareness of infant's hunger and satiety cues, concerns about feeding on a schedule, and social interaction with the infant during feeding.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Biology
Shiyu Gui, Boaz Yuval, Tobias Engl, Yongyue Lu, Daifeng Cheng
Summary: Protein feeding is crucial for successful reproduction in male insects, but its effect on reproduction is not well understood. This study used Bactrocera dorsalis as a model to investigate how protein feeding regulates sex pheromone synthesis. The results show that protein ingestion is necessary for sex pheromone synthesis in males. Although protein feeding did not affect Bacillus abundance, transcriptome analysis revealed that sarcosine dehydrogenase (Sardh) regulates sex pheromone biosynthesis by increasing glycine and threonine levels. Disrupting Sardh function decreased glycine, threonine, and sex pheromone contents, leading to reduced mating ability in males. This study establishes a connection between male feeding behavior, gene expression, and sex pheromone synthesis, which ultimately influences male copulatory behavior.
Article
Nutrition & Dietetics
Amy M. Moore, Jessica J. Smith, Brian K. Stansfield, Jennifer S. Savage, Justin A. Lavner
Summary: This study found that African American mothers have the lowest breast milk feeding rates in the United States, with rates decreasing significantly by 16 weeks. Predictors of breast milk feeding included prepregnancy BMI, working status, food insecurity, and participation in welfare programs.
Review
Oncology
Ebony Hargrove-Wiley, Barbara Fingleton
Summary: Sex hormones such as estrogens and androgens play a crucial role in the pathophysiology of various cancers by regulating genomic and cellular processes. They can modulate immune signals and activities in tumor cells and leukocytes, affecting cancer progression. Understanding the impact of sex hormones on tumor immunity in the breast cancer microenvironment is important for developing effective therapies. Combining endocrine therapy with immunotherapy can enhance the antitumor immune response.
Article
Pediatrics
Meng Yan Tang, Xiao Mei Liu, Fan Yang
Summary: This study aimed to understand the prevalence of feeding difficulties (FD) in young children at the self-feeding transition stage (6-24 months age) and determine the protective and risk predictors associated with FD. A cross-sectional study was conducted in Chengdu, Southwest China, and a total of 1,211 subjects were enrolled. The study found a prevalence of 31.4% for FD and identified 10 independent predictors, including 6 risk predictors and 4 protective predictors. These findings emphasize the importance of addressing FD and providing parents with practical preventive strategies.
FRONTIERS IN PEDIATRICS
(2023)
Article
Health Care Sciences & Services
Juan Brines, Claude Billeaud
Summary: Lactation is a critical period for mammal feeding. The debate between natural and artificial lactation continues, with a lack of consensus. Information overload may hinder the acquisition of objective knowledge and decision-making in specific circumstances.
Article
Oncology
Christian Stephens, Dori Klemanski, Maryam B. Lustberg, Anne M. Noonan, Seuli Brill, Jessica L. Krok-Schoen
Summary: The study reveals that many primary care physicians lack confidence in providing survivorship care, which may be due to inadequate training, poor communication with oncologists, and underutilization of survivorship care plans.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Infectious Diseases
Richard Dwyer, Mats Kalin
Summary: This study suggests that the sex of the attending physician may influence the level of care and antibiotic treatment chosen, and that male patients admitted with CAP were more seriously ill than female patients admitted with CAP.
INFECTIOUS DISEASES
(2021)
Article
Oncology
Renata Cangussu, Eldsamira Mascarenhas, Taiane Francieli Rebelatto, Facundo Zaffaroni, Rafaela Gomes de Jesus, Paulo Ricardo Nunes Filho, Gustavo Werutsky
Summary: The lifestyle of physicians can influence the prescription of healthy habits to breast cancer patients, with those who engage in regular physical activity more likely to offer lifestyle modification advice. Additionally, approximately half of physicians provide some form of management for overweight and obese patients.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Multidisciplinary Sciences
Xiao Qian Wang, Esther Danenberg, Chiun-Sheng Huang, Daniel Egle, Maurizio Callari, Begona Bermejo, Matteo Dugo, Claudio Zamagni, Marc Thill, Anton Anton, Stefania Zambelli, Stefania Russo, Eva Maria Ciruelos, Richard Greil, Balazs Gyorffy, Vladimir Semiglazov, Marco Colleoni, Catherine M. Kelly, Gabriella Mariani, Lucia Del Mastro, Olivia Biasi, Robert S. Seitz, Pinuccia Valagussa, Giuseppe Viale, Luca Gianni, Giampaolo Bianchini, H. Raza Ali
Summary: Imaging mass cytometry reveals that the multicellular dynamics in triple-negative breast cancer treated with immune checkpoint blockade (ICB) play a crucial role in determining treatment response. Key factors such as cell phenotype, activation state, and spatial location influence the effectiveness of ICB. By understanding the impact of multicellular organization, we can better guide adaptive therapy and achieve precision immuno-oncology.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Gary A. A. Ulaner
Summary: A 35-year-old woman with breast cancer diagnosed during pregnancy underwent FDG PET/CT 11 days after delivery. Diffuse avidity was observed in both breasts, with a more intense focus in the right breast at the site of a biopsy clip. There were no lymph node or distant metastases. The patient's active breastfeeding explained the diffuse breast avidity. This case demonstrates coexistence of both malignant and benign FDG avidity in the breasts, with a focal FDG-avid malignancy identified among elevated physiologic FDG uptake due to breastfeeding.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Medicine, General & Internal
Karim Fizazi, Josep M. Piulats, M. Neil Reaume, Peter Ostler, Ray McDermott, Joel R. Gingerich, Elias Pintus, Srikala S. Sridhar, Richard M. Bambury, Urban Emmenegger, Henriette Lindberg, David Morris, Franco Nole, John Staffurth, Charles Redfern, Maria I. Saez, Wassim Abida, Gedske Daugaard, Axel Heidenreich, Laurence Krieger, Brieuc Sautois, Andrea Loehr, Darrin Despain, Catherine A. Heyes, Simon P. Watkins, Simon Chowdhury, Charles J. Ryan, Alan H. Bryce
Summary: In this Phase 3 trial, the PARP inhibitor rucaparib demonstrated significant activity in patients with metastatic, castration-resistant prostate cancer with a deleterious BRCA alteration. The duration of imaging-based progression-free survival was significantly prolonged in the rucaparib group compared to the control group.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Behavioral Sciences
Kaat Philippe, Claire Chabanet, Sylvie Issanchou, Alice Gronhoj, Jessica Aschemann-Witzel, Sandrine Monnery-Patris
Summary: This study found differences in feeding practices and involvement between Danish mothers and fathers, with fathers tending to use higher levels of coercive control practices and mothers using more structure and autonomy support practices.
Review
Nursing
Yijing Li, Zhihua Xu, Xu Zhang, Dongfei Ma, Xiangfei Meng, Mengting Zhang, Jiao Sun
Summary: This systematic review aims to synthesise and discuss the predictors of complete oral feeding resumption in stroke patients with dysphagia after feeding tube placement. The review included 15 studies and identified factors such as demographic characteristics, swallowing function, stroke characteristics, functional status, and clinical measures that may predict the recovery. However, the current evidence is insufficient to determine the predictive effect of any single factor, indicating the need for further high-quality research.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Multidisciplinary Sciences
Alexis Maximilien Bachmann, Jean-David Morel, Gaby El Alam, Sandra Rodriguez-Lopez, Tanes Imamura de Lima, Ludger J. E. Goeminne, Giorgia Benegiamo, Sylvain Loric, Marc Conti, Maroun Bou Sleiman, Johan Auwerx
Summary: The sharp increase in global obesity prevalence is primarily due to changes in physical activity and eating behavior, but the metabolic and clinical impacts of these obesogenic conditions vary between sexes and genetic backgrounds. By analyzing genetically diverse mouse strains, researchers have found that mice, like humans, exhibit diverse physiological and biochemical responses to high-fat diet. These findings support the use of diverse mouse populations in future studies on metabolic dysfunctions.
Article
Substance Abuse
Rima T. Nakkash, Noor El Boukhari, Rima A. Afifi
Summary: The appeal of midwakh smoking among young adults in Lebanon is influenced by factors such as the practicality of having a supply of dokha, the attractiveness of midwakh smoking, and the communication and expectations related to its use. Despite experiencing negative effects, young adults find it hard to quit due to factors like stress relief and nicotine craving satisfaction. Efforts to prevent and control midwakh smoking among young adults should consider these factors.
Article
Public, Environmental & Occupational Health
Khalid Yunis, Ayah Al Bizri, Jamela Al Raiby, Pascale Nakad, Rym El Rafei, Khalid Siddeeg, Nhu Nguyen Tran Minh, Evans Buliva, Sk Md Mamunur Malik, Maha El Adawy, Ramez Mahaini, Walid Ammar
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Rima Nakkash, Melissa Mialon, Jihad Makhoul, Monika Arora, Rima Afifi, Abeer Al Halabi, Leslie London
Summary: Efforts to adopt public health policies are often undermined by private sector actors whose profits depend on the sales of unhealthy commodities. The influence of private sector actors on public health at both national and global levels has been facilitated by globalization, trade agreements, and privatization. A network promoting knowledge on governance, ethics, and conflicts of interest in the interactions between private sectors actors and those in public health has recently reached 119 members and calls for stronger guidance to address and manage this influence.
GLOBALIZATION AND HEALTH
(2021)
Letter
Medicine, General & Internal
Graham Watt, Rita Giacaman, Huda Zurayk, Espen Bjertness, Gerd Holmboe-Ottesen, Hala Ghattas, Iman Nuwayhid, Jennifer Leaning, John S. Yudkin, Khamis Elessi, Richard Sullivan, Rima Afifi, Yousef S. Khader, Harry S. Shannon
Article
Multidisciplinary Sciences
Ayah Al Bizri, Nansi S. Boghossian, Anwar Nassar, Pascale Nakad, Dina Jaber, Rabih Chahine, Gaby Fallakha, Ghaith Makhoul, Khalid Yunis
Summary: The rate of elective cesarean section in Lebanon is high, with 25% of CS deliveries being planned term elective CS. Primary and repeat CS at 37 weeks gestation increased the risk of adverse neonatal outcomes, while there were fewer associations at 38 weeks gestation. Term cesarean deliveries before 39 weeks gestation are associated with respiratory and other adverse neonatal outcomes, and delaying birth to 39 weeks can prevent a significant percentage of these outcomes.
Article
Clinical Neurology
Fatima Jaafar, Laith Haddad, Dima Habanjar, Lama Charafeddine, Khalid Yunis, Pascale E. Karam, Makram Obeid
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
(2021)
Article
Health Care Sciences & Services
Nicole Khauli, Lilian A. Ghandour, Sirine Anouti, Rima A. Afifi, Rima Nakkash, Ali Chalak, Nasser Yassin, Silvia S. Martins
Summary: The study found that there is a strong inverse relationship between awareness of the long-term effects of alcohol and harmful drinking behaviors in young people, suggesting that knowledge plays a protective role in reducing alcohol-related harm.
EASTERN MEDITERRANEAN HEALTH JOURNAL
(2021)
Article
Immunology
Ghina R. Mumtaz, Fadi El-Jardali, Mathilda Jabbour, Aya Harb, Laith J. Abu-Raddad, Monia Makhoul
Summary: Lebanon has only vaccinated 10.7% of its population against COVID-19, raising concerns about the slow vaccine rollout. Mathematical modeling shows that reaching 80% vaccine coverage by the end of 2021 can significantly reduce the severity of the epidemic, while reaching only 40% will have a lesser impact. Rapidly scaling up vaccination efforts and maintaining social distancing measures are crucial to avoid a future surge in cases that the country is unprepared for.
Article
Genetics & Heredity
Farra Chantal, Awwad Johnny, Hamadeh Lama, Khoueiry Pierre, Halawi Zeina, Yazbeck Nadine, Daher Rose, Souaid Mirna, Hamdar Layal, Yammine Tony, Yunis Khalid
Summary: Cystic fibrosis is a common genetic disease in Western countries, with this study finding a high carrier rate of 5.5%-7% in newborns in the Middle Eastern Lebanese population. The research highlights the challenges in interpreting CFTR variants in countries with limited ethnic diversity, emphasizing the importance of premarital screening programs for cystic fibrosis.
ANNALS OF HUMAN GENETICS
(2022)
Review
Public, Environmental & Occupational Health
R. A. Afifi, E. A. Parker, G. Dino, D. M. Hall, B. Ulin
Summary: This article discusses the importance of rural health research and suggests that a paradigm shift is needed to focus on the complexity and strength of rural places. It also explores the relevance of health equity frameworks, implementation science, and community-engaged approaches in promoting rural well-being.
ANNUAL REVIEW OF PUBLIC HEALTH
(2022)
Article
Substance Abuse
Hala Alaouie, Sumithra Krishnamurthy Reddiar, Malak Tleis, Lama El Kadi, Rima Afifi, Rima Nakkash
Summary: This paper provides an updated global review of waterpipe tobacco policies and adds an equity lens to assess their impact. The results show limited attention to waterpipe policies and equity considerations. The study recommends that waterpipe tobacco smoking policies prioritize equity as a goal.
Article
Social Sciences, Interdisciplinary
Asih Asikin-Garmager, Patrick Dowd, Salim George, Rima A. Afifi
Summary: This study illustrates the application of user experience evaluation in the formative evaluation of a community engagement toolkit. The findings indicate overall positive feedback on the toolkit's interface and navigation, but suggest the need for improvement on content relevance and broad appeal.
EVALUATION AND PROGRAM PLANNING
(2022)
Review
Public, Environmental & Occupational Health
Tolib Mirzoev, Stephanie M. Topp, Rima A. Afifi, Racha Fadlallah, Felix Abrahams Obi, Lucy Gilson
Summary: Health policy and systems research is crucial for developing effective health systems. However, there is a lack of capacity for this type of research, especially in low-income and middle-income countries. This paper proposes a comprehensive framework for systemic capacity strengthening in health research, highlighting the importance of collective, organizational, and network-level efforts. The framework also emphasizes the need to address power dynamics in capacity strengthening work.
Article
Public, Environmental & Occupational Health
Adriana Maldonado, Richard M. Hoffman, Barbara Baquero, Daniel K. Sewell, Helena H. Laroche, Rima Afifi, Paul A. Gilbert
Summary: Little is known about the influence of social and environmental contexts on Latino hypertension-related disparities. This study examined the influence of social determinants of cardiovascular health on medically treated hypertension, contrasting established vs. new Latino destination states. Results showed that regardless of destination state, a history of diabetes and access to healthcare were associated with receiving treatment for hypertension. In established destination states, higher education levels were linked to higher odds of treated hypertension, while in new and non-destination states, the odds were consistently lower across educational attainment levels.
JOURNAL OF IMMIGRANT AND MINORITY HEALTH
(2023)
Article
Education & Educational Research
Anna B. Correa, Hanh Pham, Rebecca Bucklin, Daniel Sewell, Rima Afifi
Summary: This study examined the impact of the COVID-19 pandemic on Resident Assistants (RAs) at a public university in the Midwest. An online survey was conducted to measure socio-demographics, stress, and well-being. The results showed that a significant proportion of RAs experienced anxiety and stress, particularly those who perceived a great impact of COVID-19 on their lives.
JOURNAL OF AMERICAN COLLEGE HEALTH
(2023)
