Article
Medicine, General & Internal
Thao Wolbert, Rahman Barry, Todd Gress, Amanda Arrington, Errington Thompson
Summary: This study explores potential barriers to colorectal cancer (CRC) screening in the West Virginia Appalachian area. Through a cross-sectional survey, patient-reported barriers were identified using the health belief model to evaluate attitudes and behaviors. The discrepancies between the screened and unscreened groups mainly stem from perceptions of discomfort from screening tests, psychological and behavior deterrents in CRC screening and diagnosis, and limited resources for accessing care, especially transportation.
SOUTHERN MEDICAL JOURNAL
(2021)
Article
Oncology
Jean A. Shapiro, Ashwini Soman, Zahava Berkowitz, Stacey A. Fedewa, Susan A. Sabatino, Janet S. de Moor, Tainya C. Clarke, V. Paul Doria-Rose, Erica S. Breslau, Ahmedin Jemal, Marion R. Nadel
Summary: In 2018, an estimated 66.9% of U.S. adults aged 50-75 had colorectal cancer screening, with colonoscopy, FOBT/FIT, and FIT-DNA being the most commonly used screening types within recommended intervals. Despite some progress, colorectal cancer testing remains low in certain population subgroups, indicating efforts are needed to reach screening goals.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Multidisciplinary Sciences
Selda Tekiner, Gulsen Ceyhun Peker, Mine Ceylan Dogan
Summary: This study evaluated the health beliefs of relatively young individuals in Turkey regarding colorectal cancer screening before the screening age, finding that attitudes towards preventive health measures are mainly associated with age, gender, education level, and marital status.
Article
Economics
Melanie Brinkmann, Leonie Diedrich, Melissa Hemmerling, Christian Krauth, Bernt-Peter Robra, Jona T. Stahmeyer, Maren Dreier
Summary: This study aimed to analyze the preferences of insurees in Germany for characteristics of colorectal cancer (CRC) screening modalities. A generic discrete choice experiment was conducted, and the results showed that insurees had different preferences for attributes such as preparation, CRC mortality, and CRC incidence.
Article
Public, Environmental & Occupational Health
Samare P. I. Huls, Esther W. de Bekker-Grob
Summary: This study aimed to assess the internal and external validity of discrete choice experiments (DCEs) in the context of colorectal cancer (CRC) screening and explore the discrepancy between stated and revealed preferences. The findings showed high internal and external validity, with the accuracy of predicting choices ranging from 90% to 95%. The differences between stated and revealed preferences were attributed to respondents' health and the support of their general practitioner. The study suggests further investigation into the validity of DCEs and the role of model complexity.
SOCIAL SCIENCE & MEDICINE
(2022)
Editorial Material
Medicine, General & Internal
John M. M. Carethers
Summary: A 56-year-old man with no significant medical history declined screening colonoscopy in the past but now wants a less invasive test due to his father's death from colorectal cancer. What is the next course of action?
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Review
Oncology
Enea Ferlizza, Rossella Solmi, Michela Sgarzi, Luigi Ricciardiello, Mattia Lauriola
Summary: Colorectal cancer (CRC) ranks as the third most common cancer worldwide, emphasizing the significance of early detection. Screening through fecal occult blood tests has shown to reduce CRC incidence and mortality, however, low participation rates and false positives are key challenges. Recent research has focused on new fecal tests, biomarkers, and liquid biopsy methods to enhance accuracy and participation in CRC screening.
Article
Public, Environmental & Occupational Health
Krishna P. Sharma, Amy DeGroff, Annette E. Maxwell, Allison M. Cole, Ngoc Cam Escoffery, Peggy A. Hannon
Summary: Client reminders, provider assessment and feedback, and colorectal cancer screening champions were found to be associated with increased clinic-level colorectal cancer screening rates according to this study. The universal implementation of these strategies can substantially increase colorectal cancer screening rates in the U.S.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Article
Oncology
Xuan Quy Luu, Kyeongmin Lee, Jae Kwan Jun, Mina Suh, Kyu-Won Jung, Kui Son Choi
Summary: This study investigated the long-term survival effects of colorectal cancer screening based on screening history and interval time since screening. The results showed that colorectal cancer screening was positively associated with favorable prognosis, especially among individuals screened within 1 year before diagnosis.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Oncology
Elif Donmez, Nursen O. Nahcivan, Susan M. Rawl
Summary: The aim of this study was to assess the validity and reliability of the Turkish version of the Instruments to Measure CRCS Benefits and Barriers. The results showed that the emoji-based facial scale is a valid and reliable tool for measuring the benefits and barriers perceptions of 50- to 70-year-old Turkish adults. This tool can provide insights for healthcare professionals to understand individuals' perceived benefits and barriers of colorectal cancer screening.
Article
Gastroenterology & Hepatology
Aasma Shaukat, Charles J. Kahi, Carol A. Burke, Linda Rabeneck, Bryan G. Sauer, Douglas K. Rex
Summary: This article provides an update on the 2009 American College of Gastroenterology CRC screening guidelines and discusses detailed recommendations for CRC screening in average-risk individuals and those with a family history of CRC, as well as the role of aspirin for chemoprevention, quality indicators for colonoscopy, organized CRC screening approaches, and improving adherence to CRC screening. The optimization of CRC screening is essential to effectively reduce CRC incidence and mortality, which can be achieved through high rates of adherence, quality monitoring, evidence-based guidelines, and the removal of barriers throughout the care spectrum. Developing cost-effective, highly accurate, noninvasive modalities to improve overall adherence to the screening process is also a desirable goal.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Medicine, General & Internal
Erica K. Barnell, Elizabeth M. Wurtzler, Julie La Rocca, Thomas Fitzgerald, Jessica Petrone, Yansheng Hao, Yiming Kang, Faith L. Holmes, David A. Lieberman
Summary: This study evaluated the sensitivity and specificity of a noninvasive multitarget stool RNA test for colorectal cancer and precancerous lesions. The results showed that the test had a sensitivity of 94% for detecting colorectal cancer and 46% for detecting advanced adenomas, with a specificity of 88%.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Review
Gastroenterology & Hepatology
Marina Hanna, Neelendu Dey, William M. Grady
Summary: Colorectal cancer is a common cancer globally and is a leading cause of cancer-related deaths. Current screening methods for colorectal cancer have limitations and many people are not compliant with screening recommendations. Novel screening tests based on advances in molecular biology, genetics, and epigenetics, as well as sequencing technologies and computational analytic methods, have been developed to improve early detection of colorectal cancer.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Mireia Obon-Santacana, Anna Diez-Villanueva, Maria Henar Alonso, Gemma Ibanez-Sanz, Elisabet Guino, Ana Lopez, Lorena Rodriguez-Alonso, Alfredo Mata, Ana Garcia-Rodriguez, Andres Garcia Palomo, Antonio J. Molina, Montse Garcia, Gemma Binefa, Vicente Martin, Victor Moreno
Summary: Different risk-based colorectal cancer screening strategies, including the use of polygenic risk scores, have been evaluated to enhance effectiveness. This study assessed the utility of polygenic risk scores in a fecal immunochemical test-based screening program and found that while it plays a role along the CRC tumorigenesis pathway, its ability to stratify the general population or act as a second test after a positive FIT result remains uncertain.
Review
Gastroenterology & Hepatology
Aasma Shaukat, Theodore R. Levin
Summary: This Review provides an overview of current CRC screening options worldwide, including colonoscopy and stool-based tests. It also highlights the key features of each modality and describes new screening tests under development.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2022)
Article
Oncology
Jesse J. Plascak, Andrew G. Rundle, Xinyi Xu, Stephen J. Mooney, Mario Schootman, Bo Lu, Jason Roy, Antoinette M. Stroup, Adana A. M. Llanos
Summary: The study found that physical disorder in residential environments is associated with worse tumor prognostic factors and survival among women with breast cancer, particularly those diagnosed at an early stage.
Article
Public, Environmental & Occupational Health
Mira L. Katz, Brent Emerson, Victoria L. Champion, Peter H. Schwartz, Thomas F. Imperiale, Hala Fatima, Electra D. Paskett, Susan M. Perkins, Yan Tong, Netsanet Gebregziabher, Connie Krier, Kevin Tharp, Caeli Malloy, Sylvia Strom, Susan M. Rawl
Summary: In the process evaluation of a comparative effectiveness trial for a mailed interactive educational DVD intervention to promote colorectal cancer screening, participants found the information helpful, learned new information, and were generally satisfied with the content of the DVD. The majority would recommend the DVD to others and some reported a change in their opinion about screening after watching the DVD.
HEALTH PROMOTION PRACTICE
(2022)
Article
Oncology
Angela J. Fong, Andrew M. Evens, Elisa Bandera, Adana A. M. Llanos, Katie A. Devine, Shawna Hudson, Bo Qin, Lisa E. Paddock, Antoinette M. Stroup, Sara Frederick, Carissa Greco, Sharon L. Manne
Summary: This study aimed to characterize the preparedness for survivorship and evaluate the factors associated with it, including sociodemographic, medical, survivorship care transition experiences, practical and psychological factors. The findings revealed that many cancer survivors felt unprepared for survivorship and desired more information about follow-up tests and maintaining good health. Factors such as receiving chemotherapy, limited transition care planning, limited discussion of medical and psychosocial effects, high information needs, and financial hardship predicted low preparedness.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Article
Public, Environmental & Occupational Health
Jesse J. Plascak, Stephen J. Mooney, Mario Schootman, Andrew G. Rundle, Adana A. M. Llanos, Bo Qin, Chi-Chen Hong, Kitaw Demissie, Elisa Bandera, Xinyi Xu
Summary: This study tested the accuracy and validity of spatio-temporal model prediction of observed neighborhood physical disorder collected from virtual audits. The results showed that the full models had lower prediction error compared to large-scale models and had higher correlations with respondent-reported perceptions of physical disorder. The study demonstrates the validity of a spatio-temporal Kriging model for predicting observed physical disorder.
SPATIAL AND SPATIO-TEMPORAL EPIDEMIOLOGY
(2022)
Article
Medicine, Research & Experimental
Erika Biederman, Ryan Baltic, Mira L. Katz, Susan Rawl, Eric Vachon, Patrick O. Monahan, Timothy E. Stump, Carla Kettler, Lisa Carter, Gregory Young, Wendy Xu, Electra D. Paskett, Victoria Champion
Summary: Rural women have a higher mortality rate from breast, cervical, and colorectal cancer compared to urban women. Screening behaviors for these three cancers share similar beliefs and barriers. However, published interventions have not simultaneously addressed screening for all three cancers, even though multiple behavior change interventions have been proven effective. This study compared the effectiveness of different interventions to increase the screening rates among rural women (aged 50-74) for breast, cervical, and colorectal cancer.
CONTEMPORARY CLINICAL TRIALS
(2022)
Article
Public, Environmental & Occupational Health
Mira L. Katz, Leigha Senter, Paul L. Reiter, Brent Emerson, Alysha C. Ennis, Kate P. Shane-Carson, Amber Aeilts, Hayley R. Cassingham, Patrick M. Schnell, Doreen M. Agnese, Amanda E. Toland, Kevin Sweet
Summary: This study developed a web-based narrative intervention guided by health behavior theory and stakeholder feedback to replace conventional pre-test genetic counseling for women at elevated risk of breast cancer. The intervention, which is patient-centered, aims to provide convenience and personalized post-test counseling. Its efficacy is being evaluated in a randomized controlled trial to determine its impact on adherence to guidelines, knowledge, perception of breast cancer risk, worry, and satisfaction with counseling. If successful, this intervention has the potential to improve the genetic testing and counseling process, inform best practices, and reduce the burden on genetic counseling workforce.
PATIENT EDUCATION AND COUNSELING
(2023)
Article
Biotechnology & Applied Microbiology
Paul L. Reiter, Amy L. Gower, Dale E. Kiss, Abigail B. Shoben, Mira L. Katz, Jose A. Bauermeister, Electra D. Paskett, Annie-Laurie Mcree
Summary: This study examines the effects of a theoretically-informed, web-based HPV vaccination intervention on cognitive outcomes among young gay, bisexual, and other men who have sex with men. The results show that the intervention group had greater improvements in knowledge, attitudes, and beliefs related to HPV vaccination compared to the control group.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Oncology
Victoria L. Champion, Patrick O. Monahan, Timothy E. Stump, Erika B. Biederman, Eric Vachon, Mira L. Katz, Susan M. Rawl, Ryan D. Baltic, Carla D. Kettler, Natalie L. Zaborski, Electra D. Paskett
Summary: This research investigated the effectiveness of mailed DVD and DVD + PN interventions in increasing mammography screening among rural women. The combined DVD + PN group had over 5 times higher rate of receiving a mammogram within 12 months compared to usual care. Guideline-based mammography screening is crucial for reducing breast cancer mortality, but rural women have lower up to date rates compared to urban women.
Article
Public, Environmental & Occupational Health
Mira L. Katz, Timothy E. Stump, Patrick O. Monahan, Brent Emerson, Ryan Baltic, Gregory S. Young, J. Madison Hyer, Electra D. Paskett, Victoria L. Champion, Susan M. Rawl
Summary: This study examines the accuracy of self-reported cancer screening behaviors in rural areas and compares it with medical record documentation. The results suggest that self-reported rates of cancer screening may be overestimated when compared to medical records.
PREVENTIVE MEDICINE REPORTS
(2022)
Article
Oncology
Paul L. Reiter, Amy L. Gower, Dale E. Kiss, Abigail B. Shoben, Mira L. Katz, Jose A. Bauermeister, Electra D. Paskett, Annie -Laurie McRee
Summary: This study reports the efficacy of a web-based HPV vaccination intervention for young gay, bisexual, and other men who have sex with men (YGBMSM). The intervention, called Outsmart HPV, includes online content and monthly interactive or unidirectional text reminders. Results show that participants in the intervention groups were more likely to initiate and complete the HPV vaccine series compared to the control group. Participants also reported higher satisfaction with the intervention. Overall, Outsmart HPV is a promising tool for increasing HPV vaccination among YGBMSM.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Health Care Sciences & Services
Mira L. Katz, Abigail B. Shoben, Sabrina Newell, Christina Hall, Brent Emerson, Darrell M. Gray II, Subhankar Chakraborty, Paul L. Reiter
Summary: A video brochure was developed to address barriers to fecal immunochemical test (FIT) return for colorectal cancer (CRC) screening. The study compared three groups and found that patients who received the video brochure had a higher return rate, indicating the potential effectiveness of using video brochures in improving CRC screening in rural regions.
JOURNAL OF RURAL HEALTH
(2023)
Article
Nutrition & Dietetics
Angela J. Fong, Adana A. M. Llanos, Adiba Ashrafi, Nur Zeinomar, Sagar Chokshi, Elisa V. Bandera, Katie A. Devine, Shawna V. Hudson, Bo Qin, Denalee O'Malley, Lisa E. Paddock, Antoinette M. Stroup, Andrew M. Evens, Sharon L. Manne
Summary: The study aimed to assess adherence to health behavior guidelines among cancer survivors and identify characteristics associated with different adherence levels. Latent class analysis identified three classes: lower-risk, moderate-risk, and high-risk lifestyle. Lower-risk participants had the highest adherence to guidelines, while characteristics such as race, marital status, education level, and cancer stage were associated with moderate or high-risk adherence. These findings can inform interventions to promote health behavior adherence among higher risk cancer survivors.
Article
Public, Environmental & Occupational Health
Electra D. Paskett, Aaron J. Kruse-Diehr, Jill M. Oliveri, Robin C. Vanderpool, Darrell M. Gray, Michael L. Pennell, Bin Huang, Gregory S. Young, Darla Fickle, Mark Cromo, Mira L. Katz, Paul L. Reiter, Melinda Rogers, David A. Gross, Vickie Fairchild, Wendy Xu, Angela Carman, Jean M. Walunis, Ann Scheck McAlearney, Timothy R. Huerta, Saurabh Rahurkar, Erika Biederman, Mark Dignan
Summary: The Appalachian regions of Kentucky and Ohio have a high mortality rate of colorectal cancer (CRC) in the USA. This study aims to use implementation science strategies to evaluate and improve CRC screening processes. The study consists of a planning phase and an implementation phase, with the goal of increasing the uptake of guideline-recommended CRC screening in underserved areas.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2023)
Article
Environmental Sciences
Adana A. M. Llanos, Amber Rockson, Kylie Getz, Patricia Greenberg, Eva Portillo, Jasmine A. McDonald, Dede K. Teteh, Justin Villasenor, Carolina Lozada, Jamirra Franklin, Vaishnavi More, Zorimar Rivera-Nunez, Carolyn W. Kinkade, Emily S. Barrett
Summary: Evidence shows that certain groups, such as femme-identifying individuals and racial and ethnic minorities, bear unequal burdens of chemical exposures from personal care products (PCPs). This study used an online questionnaire to assess PCP purchasing and usage behaviors and perceptions among a sample of US adults. The findings indicate that females use more PCPs than males, and there are variations in usage patterns among different racial and ethnic groups. Study participants generally expressed moderate concern about exposures and health effects from using PCPs, with minimal differences by gender, race, and ethnicity.
ENVIRONMENTAL RESEARCH
(2023)
Article
Oncology
Irina B. Grafova, Sharon L. Manne, Shawna V. Hudson, Jennifer Elliott, Adana A. M. Llanos, Biren Saraiya, Paul R. Duberstein
Summary: This study examines the associations between functional limitations and medical and credit card debt among cancer survivor families and finds sex differences. The results show that credit card debt is more common than medical debt, and families of male cancer survivors are more likely to have medical debt and less likely to have credit card debt compared to families of female cancer survivors.
SUPPORTIVE CARE IN CANCER
(2023)