Article
Primary Health Care
Emma Baljet, Hilde Luijks, Lisette Van den Bemt, Tjard R. Schermer
Summary: This study explored the associations between 18 chronic comorbid conditions and asthma exacerbation occurrence. Obesity and rheumatoid arthritis were found to be associated with severe asthma exacerbation. Age-stratified analysis showed that soft drug use, obesity, depression, thyroid problems, and rheumatoid arthritis were associated with moderate or severe exacerbation occurrence.
NPJ PRIMARY CARE RESPIRATORY MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Sumeet K. K. Asrani, Lauren Hall, Vikrant Reddy, Gerald Ogola, Manhal Izzy
Summary: This study examines the impact of comorbid chronic diseases on mortality in patients with cirrhosis. The presence of multiple chronic diseases increases the risk of mortality. Diabetes mellitus, chronic kidney disease, and cardiovascular disease are the most common comorbidities, and it is important to prioritize their management in cirrhosis patients.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Allergy
Andrej A. Petrov, Adil Adatia, Stephen Jolles, Parameswaran Nair, Antoine Azar, Jolan E. Walter
Summary: This review discusses new emerging pulmonary phenotypes associated with antibody deficiency, as well as antibody deficiency syndromes that lead to end-stage lung disease and the indications for lung transplantation in primary immunodeficiency disease. These challenging cases require timely and individualized strategies for genetic and immunologic diagnosis, decisions about therapeutic approaches, and long-term monitoring.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Article
Health Care Sciences & Services
Ren-Long Jan, Chung-Han Ho, Jhi-Joung Wang, Sung-Huei Tseng, Yuh-Shin Chang
Summary: This study found a strong association between Sjogren syndrome, post ocular surgery, systemic infection disease, systemic autoimmune disease, and scleritis.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Medicine, Research & Experimental
Hsun Chang, Chien-Feng Kuo, Teng-Shun Yu, Liang-Yin Ke, Chung-Lieh Hung, Shin-Yi Tsai
Summary: This study found that infection with common pathogens, including bacteria and viruses, is associated with an increased risk of developing Chronic Fatigue Syndrome (CFS), based on an analysis of data from Taiwan's National Health Insurance Research Database.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Psychology, Clinical
Noelle E. Carlozzi, Nicholas R. Boileau, Susan L. Murphy, Tiffany J. Braley, Anna L. Kratz
Summary: The study aimed to validate the Pittsburgh Fatigability Scale in three different groups and found that it exhibited acceptable psychometric properties. However, some measurement estimates did not meet expectations, and item-total correlations for two items were lower than expected.
JOURNAL OF HEALTH PSYCHOLOGY
(2021)
Article
Medicine, Research & Experimental
Xiaolin Jia, Alexandra S. Lee, Monali Manohar, Sayantani B. Sindher, Neera Ahuja, Maja Artandi, Catherine A. Blish, Andra L. Blomkalns, Iris Chang, William J. Collins, Manisha Desai, Hena Naz Din, Evan Do, Andrea Fernandes, Linda N. Geng, Yael Rosenberg-Hasson, Megan Ruth Mahoney, Abigail L. Glascock, Lienna Y. Chan, Sharon Y. Fong, Chan Zuckerberg Biohub, Maira Phelps, Olivia Raeber, Natasha Purington, Katharina Roltgen, Angela J. Rogers, Theo Snow, Taia T. Wang, Daniel Solis, Laura Vaughan, Michelle Verghese, Holden Maecker, Richard Wittman, Rajan Puri, Amy Kistler, Samuel Yang, Scott D. Boyd, Benjamin A. Pinsky, Sharon Chinthrajah, Kari C. Nadeau
Summary: This study investigated the prolonged symptoms after SARS-CoV-2 infection, factors influencing the development of long-term symptoms, and the correlation with biomarkers. The findings showed that patients with different disease severities had similar risks of developing post-COVID-19 syndrome, and comorbid lung disease and lower levels of initial IgG response were associated with longer symptom duration.
Article
Psychiatry
Eike Wehling, Josef J. Bless, Marco Hirnstein, Bodil Krakvik, Einar Vedul-Kjelsas, Kenneth Hugdahl, Anne Martha Kalhovde, Frank Laroi
Summary: Olfactory hallucinations, perceptions of smell without a chemical trigger, were reported by 4.2% of a Norwegian community sample with a higher prevalence among young individuals and females. Anxiety symptoms and stressful life events were associated with olfactory hallucinations, suggesting a potential link to negative impact on functioning and increased risk for psychopathology. Further research is needed to better understand this phenomenon.
PSYCHIATRY RESEARCH
(2021)
Article
Medicine, Research & Experimental
Chi Chen, Hei-Tung Yip, Kam-Hang Leong, Wei-Cheng Yao, Chung-Lieh Hung, Ching-Huang Su, Chien-Feng Kuo, Shin-Yi Tsai
Summary: A population-based cohort study in Taiwan found that patients with chronic fatigue syndrome (CFS) commonly have depression and anxiety disorder before the diagnosis. The study also revealed an increased risk of CFS among individuals taking certain types of antidepressants and analgesic drugs.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Hui-Min Hsieh
Summary: The Cancer Screening Quality Improvement Program (CAQIP) in Taiwan, implemented in 2010, provides financial support to hospitals to improve accessibility. A study found that CAQIP is positively associated with increased mammography participation among women aged 50-69, especially for those without comorbid conditions.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Multidisciplinary Sciences
Evguenia Nepotchatykh, Iurie Caraus, Wesam Elremaly, Corinne Leveau, Mohamed Elbakry, Christian Godbout, Bita Rostami-Afshari, Diana Petre, Nasrin Khatami, Anita Franco, Alain Moreau
Summary: This study investigates the differential expression profiles of 11 circulating miRNAs associated with ME/CFS pathogenesis in FM patients and those with a comorbid diagnosis of FM associated with ME/CFS. The study reveals differential miRNA expression between ME/CFS, FM, and ME/CFS + FM, which correlate to symptom severity. A machine-learning model based on the levels of these miRNAs is provided for discriminating between ME/CFS, FM, and ME/CFS + FM. The study suggests these miRNAs as potential biomarkers for distinguishing ME/CFS from FM, highlighting the importance of proper diagnosis for elucidating the pathophysiology and establishing effective treatments for both diseases.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Susanna Maddali Bongi, Giovanni Vitali Rosati, Guglielmo Bonaccorsi, Chiara Lorini
Summary: This study aimed to estimate the prevalence of Juvenile Fibromyalgia (JFM) in an Italian population-based convenience sample by involving family pediatricians, and to assess its relationships with contextual factors. A total of 7275 questionnaires were collected, with 38 children (0.5%) meeting the 2010 ACR criteria, and 4 (0.1%) meeting the 2016 ACR criteria. The analysis showed that older children, those with leisure time injuries causing persistent pain, and children with parents diagnosed with fibromyalgia or diffuse pain were more likely to meet the 2010 ACR criteria. The findings suggest the importance of using the 2010 ACR criteria for JFM in children and adolescents, and highlight the need for pediatricians to pay attention to important predictors of JFM.
Article
Public, Environmental & Occupational Health
Maud Wieczorek, Clement Meier, Sarah Vilpert, Robert Reinecke, Carmen Borrat-Besson, Jurgen Maurer, Matthias Kliegel
Summary: This study aimed to investigate the relationship between multimorbidity, the number of chronic conditions, and health literacy levels in adults aged 58+ in Switzerland. The study found that individuals with multiple chronic conditions were more likely to have lower health literacy levels, highlighting the need to improve health literacy in this population.
Article
Medicine, Research & Experimental
Kam-Hang Leong, Hei-Tung Yip, Chien-Feng Kuo, Shin-Yi Tsai
Summary: This study provides 12-year nationwide epidemiological data on chronic fatigue syndrome (CFS) in Taiwan, showing a higher prevalence of various comorbidities in CFS patients compared to controls. Treatment options including SSRIs, SNRIs, SARIs, TCAs, BZD, NDRIs, muscle relaxants, analgesics, psychotherapies, and exercise therapies were prescribed more frequently in the CFS cohort.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Engineering, Manufacturing
Chola Elangeswaran, Antonio Cutolo, Simone Gallas, Tien Dung Dinh, Nicolas Lammens, Hunor Erdelyi, Matthias Schulz, Gokula Krishna Muralidharan, Lore Thijs, Tom Craeghs, Evy De Bruycker, Koen Vanden Bore, Stijn Clijsters, Jan Peirs, Win Desmet, Win Van Paepeghem, Brecht Van Hooreweder
Summary: This study presents a methodology to predict and evaluate the fatigue behavior of additively manufactured components. Through experimental testing and machine learning, the study can accurately predict the fatigue behavior under unknown process conditions, and apply it in a fatigue durability prediction solver.
ADDITIVE MANUFACTURING
(2022)