Article
Urology & Nephrology
Hae-Ryong Yun, Young Su Joo, Hyung Woo Kim, Jung Tak Park, Tae Ik Chang, Nak-Hoon Son, Tae-Hyun Yoo, Shin-Wook Kang, Suah Sung, Kyu-Beck Lee, Joongyub Lee, Kook-Hwan Oh, Seung Hyeok Han
Summary: An elevated coronary artery calcification score (CACS) is associated with increased cardiovascular disease risk in patients with CKD. The study found that higher CACS is also associated with a significantly increased risk of adverse kidney outcomes and CKD progression.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Psychiatry
Trine Trab, Rubina Attar, Svend Eggert Jensen, Simon Grontved, Jens Brondum Frokjaer, Christoffer Polcwiartek, Rene Ernst Nielsen
Summary: The study found that the amount of coronary artery calcium in patients with schizophrenia follows norm percentiles, and variables associated with the calcium score are similar in patients with schizophrenia and the general population. The findings suggest that the calcium score may not be sufficient to detect the risk of coronary heart disease in patients with schizophrenia. Future studies should explore other measures of subclinical coronary heart disease for early detection and intervention.
Article
Cardiac & Cardiovascular Systems
Fei Gao, Yue Ping Li, Xiao Teng Ma, Zhi Jian Wang, Dong Mei Shi, Yu Jie Zhou
Summary: The study indicates that the combination treatment of PCSK9 inhibitors and statins significantly reduces the rate of coronary artery calcification progression.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Health Care Sciences & Services
Yana Polonskaya, Elena Kashtanova, Ivan S. Murashov, Evgenia Striukova, Alexey Kurguzov, Ekaterina M. Stakhneva, Viktoria S. Shramko, Nikolay A. Maslatsov, Aleksandr M. Chernyavsky, Yulia Ragino
Summary: The study investigated the relationship between matrix metalloproteinases and coronary artery calcification. Results showed the involvement of some MMPs, particularly MMP-9, in the calcification process. MMP-1, MMP-7, and MMP-12 were associated with CHD and may serve as potential biomarkers for further research.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Endocrinology & Metabolism
Yoosun Cho, Yoosoo Chang, Seungho Ryu, Yejin Kim, Hyun-Suk Jung, Jeonggyu Kang, In Young Choi, Chan-won Kim, Hyungseok Oh, Sarah H. Wild, Christopher D. Byrne
Summary: This study evaluated the effect of changes in prediabetes on subclinical atherosclerosis and found that persistence of prediabetes or progression to diabetes increased the risk of coronary artery calcification.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Xiadan Xiang, Ji He, Wei Zhang, Qiang He, Yueming Liu
Summary: This study found a close association between cardiovascular disease and chronic kidney disease in CKD patients, with vascular calcification as a major predictor of cardiovascular disease. Vascular calcification was found to be associated with changes in bone and mineral metabolism, and bone metabolism and inflammatory markers were positively correlated with CAC scores. Additionally, a higher risk of all-cause mortality and cardiovascular hospitalization was observed when the CAC score exceeded 400.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Sida Jia, Jianxin Li, Ce Zhang, Yue Liu, Deshan Yuan, Na Xu, Xueyan Zhao, Runlin Gao, Yuejin Yang, Bo Xu, Zhan Gao, Jinqing Yuan, Yin Zhang
Summary: The study indicates that moderate/severe coronary artery calcification in patients undergoing PCI is associated with increased risk of long-term Major Adverse Cardiovascular Events (MACE). Patients with moderate/severe CAC had higher rates of 5-year unplanned revascularization and MACE.
CIRCULATION JOURNAL
(2021)
Article
Transplantation
Ida M. H. Sorensen, Sasha S. Bjergfelt, Henrik O. Hjortkjaer, Klaus F. Kofoed, Theis Lange, Bo Feldt-Rasmussen, Christina Christoffersen, Susanne Bro
Summary: This study found that calcium scores in the coronary, carotid, and thoracic arteries are independent predictors of major adverse cardiovascular events and all-cause mortality in patients with chronic kidney disease. The potential of calcification in these three arterial sites for predicting cardiovascular events and mortality was most pronounced.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Medical Laboratory Technology
Xu Cheng, Cunqing Yang, Chun Gu, Min Wu, Jun Li, Xueyun Hou, Jiaxin Fei, Li Sun, Cheng An, Guijian Liu, Fengxiang Shi, Bo Pang
Summary: This study aimed to explore the association between serum vitamin K concentrations and coronary artery calcification score. The results showed that serum vitamin K1 and MK-4 concentrations were significantly lower in middle-aged and elderly cohorts with increasing calcification scores. Vitamin K1 concentration was found to be negatively correlated with the calcification score in individuals who already had calcification. Further research is needed to investigate the role of serum vitamin K concentration detection in guiding vitamin K supplementation in patients with coronary calcification.
CLINICA CHIMICA ACTA
(2022)
Article
Multidisciplinary Sciences
Hiroki Okabe, Yoshitaka Muraoka, Yutaro Naka, Koshi Setoyama, Konosuke Inoue, Toshiya Miura, Akiyoshi Shimizu, Reo Anai, Tetsu Miyamoto, Yuki Tsuda, Masaru Araki, Shinjo Sonoda, Masaharu Kataoka
Summary: Nutritional status has a significant effect on coronary atherosclerosis in hemodialysis patients, and malnutrition can lead to the progression of coronary artery disease. Optical coherence tomography can be used to evaluate the impact of nutritional status on coronary atherosclerosis in hemodialysis patients.
Article
Cardiac & Cardiovascular Systems
Da-Hye Son, Hyun-Su Ha, Hye S. Lee, Donghee Han, Su-Yeon Choi, Eun J. Chun, Hae-Won Han, Sung H. Park, Jidong Sung, Hae O. Jung, Ji-Won Lee, Hyuk-Jae Chang
Summary: The study demonstrates the positive association between the new visceral adiposity index (NVAI) and coronary artery calcification and arterial stiffness in asymptomatic Korean adults. NVAI showed better predictive ability for cardiovascular disease risk compared to other visceral adiposity markers.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Review
Cardiac & Cardiovascular Systems
Zhuoming Dai, Xiangyu Zhang
Summary: The prevalence of chronic kidney disease (CKD) worldwide has been increasing, with adverse cardiovascular events becoming the leading cause of life-threatening events in CKD patients. Vascular calcification, especially in the coronary arteries, is more prevalent, severe, rapidly progressive, and harmful in CKD patients. Unique features and risk factors contribute to vascular calcification in CKD patients, including phenotypic transformation of vascular smooth muscle cells, electrolyte and endocrine dysfunction, uremic toxin accumulation, and other novel factors. Understanding the mechanism of vascular calcification in patients with renal insufficiency can provide insights for prevention and treatment. This review focuses on the impact of CKD on vascular calcification, particularly coronary artery calcification, and discusses recent research on pathogenesis and factors involved.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Zhen Xie, Jing Zhu, Wenjia Li, Luzhou Liu, Kaimin Zhuo, Ru Yang, Fubi Hu
Summary: This study demonstrated that epicardial fat volume (EFV) is associated with coronary artery disease (CAD) and may serve as a promising marker of CAD. Additionally, EFV is correlated with high-risk plaque and lesion-specific ischemia, suggesting a potential role of epicardial adipose tissue (EAT) in myocardial ischemia and in determining patients' risk profile.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Health Care Sciences & Services
Leon G. Martens, Daan van Hamersveld, Saskia le Cessie, Ko Willems van Dijk, Diana van Heemst, Raymond Noordam
Summary: Low socioeconomic status (SES) is associated with increased cardiovascular risk factors and coronary artery disease (CAD) risk. This study found that SES can modify the association between classical cardiovascular risk factors and CAD in European-ancestry participants. Furthermore, the risk for CAD attributable to increased body mass index (BMI) is not the same across different SES groups.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gildo Gardinalli-Filho, Jose Victor Dantas, Georgia Petri Nahas, Daniel Araujo Brito Buttros, Fabio Cardoso Carvalho, Eduardo Carvalho-Pessoa, Heloisa De Luca Vespoli, Eliana Aguiar Petri Nahas
Summary: This study found that the presence of BAC was not associated with the severity of CAD in postmenopausal women. Women with BAC were older, had a longer time since menopause, and had a higher incidence of smoking.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Crystal W. Cene, Xiaoyan Iris Leng, Khushnood Faraz, Matthew Allison, Khadijah Breathett, Chloe Bird, Mace Coday, Giselle Corbie-Smith, Randi Foraker, Nkechinyere N. Ijioma, Milagros C. Rosal, Shawnita Sealy-Jefferson, Tetyana P. Shippee, Candyce H. Kroenke
Summary: The association between social isolation and heart failure risk in older adults is not yet clear.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Health Care Sciences & Services
Linda C. Gallo, Addie L. Fortmann, Taylor L. Clark, Scott C. Roesch, Julia I. Bravin, Samantha Spierling R. Bagsic, Haley Sandoval, Kimberly L. Savin, Todd Gilmer, Gregory A. Talavera, Athena Philis-Tsimikas
Summary: This study tested the effectiveness of a culturally appropriate care transitions program for Latino adults with multiple cardiometabolic conditions and behavioral health concerns. The program did not reduce hospital utilization or improve patient-reported outcomes.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Harpreet S. S. Bhatia, Robyn L. L. McClelland, Julie Denenberg, Matthew J. J. Budoff, Matthew A. A. Allison, Michael H. H. Criqui
Summary: This study evaluated the association between coronary artery calcium (CAC) density and cardiovascular disease risk across different levels of CAC volume. The combination of CAC density and volume improved risk prediction for coronary heart disease. Higher density was associated with lower risk at volume ≤ 130 mm(3), suggesting a potentially clinically useful cut point. Further research is needed to integrate these findings into a unified CAC scoring method.
CIRCULATION-CARDIOVASCULAR IMAGING
(2023)
Review
Psychology, Clinical
Taylor L. Clark, Kimberly L. Savin, Perla Perez-Ramirez, Tania Valdez, Gloria Toba, Linda C. Gallo
Summary: This review examines the effectiveness of eHealth weight loss interventions for adults with low income and the strategies used to tailor them. The results suggest that eHealth interventions can lead to modest weight reductions, but the evidence is limited. Further research is needed to determine the effectiveness of eHealth interventions in this population.
Article
Cardiac & Cardiovascular Systems
Rita Peila, Xiaonan Xue, Qibin Qi, Andrew J. Dannenberg, Matthew A. Allison, Karen C. Johnson, Michael J. LaMonte, Robert A. Wild, Bernhard Haring, Kathy Pan, Hilary A. Tindle, Randi Foraker, Nazmus Saquib, Ana Barac, Thomas E. Rohan
Summary: A healthy lifestyle, including a healthy diet, light alcohol consumption, no smoking, and moderate or intense physical activity, is associated with a reduced risk of cardiovascular disease.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Tamara Horwich, Preethi Srikanthan, Anisha Gaitonde, Karol Watson, Matthew Allison, Richard Kronmal
Summary: Obesity, measured by body mass index, is a risk factor for cardiovascular disease. However, the role of body composition components such as fat and lean mass is not well-studied. This study found that higher lean mass, but not fat mass, was significantly associated with coronary artery calcification, indicating the development of subclinical cardiovascular disease. Further exploration of the relationship between body composition components and cardiovascular disease is needed.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Kelsie M. M. Full, Tianyi Huang, Neomi A. A. Shah, Matthew A. A. Allison, Erin D. D. Michos, Daniel A. A. Duprez, Susan Redline, Pamela L. L. Lutsey
Summary: This study examined the association between sleep regularity and subclinical atherosclerosis. The results showed that irregular sleep duration and sleep timing were associated with early-stage atherosclerosis. Participants with greater sleep duration irregularity and irregular sleep timing were more likely to have high coronary artery calcium burden and abnormal ankle-brachial index.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Oncology
Humberto Parada Jr, Margaret S. Pichardo, Linda C. Gallo, Gregory A. Talavera, Corinne McDaniels-Davidson, Frank J. Penedo, David J. Lee, Wassim Tarraf, Tayna P. Garcia, Martha L. Daviglus, Hector M. Gonzalez
Summary: This study examined the association between cancer history and neurocognitive test performance among middle-aged and older Hispanic/Latinos. The results showed that a history of cervical cancer in women was associated with memory decline, possibly reflecting the impacts of systemic cancer therapies. On the other hand, a history of prostate cancer in men was associated with improvements in cognitive performance, perhaps due to engaging in health promoting behaviors following cancer.
Article
Health Care Sciences & Services
Chelsea C. Hays Weeks, Alison A. Moore, Matthew Allison, Kevin Patrick, Mark W. Bondi, Camille Nebeker, Thomas Liu, David Wing, Michael Higgins, Sheri J. Hartman, Robert A. Rissman, Zvinka Z. Zlatar
Summary: This study aims to develop an innovative intervention that utilizes mobile health technology to help older adults increase physical activity in free-living environments. By providing real-time feedback, older adults can maintain moderate-to-vigorous physical activity during exercise sessions to reduce the burden of Alzheimer's disease and related dementias and improve quality of life. The importance of this study lies in applying laboratory findings to everyday life and better understanding the impact of moderate-to-vigorous physical activity on brain and cognitive health.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Geriatrics & Gerontology
Venus Chiu, Jacek K. Urbanek, Amal A. Wanigatunga, Matthew A. Allison, Shoshana H. Ballew, Yasmin Mossavar-Rahmani, Daniela Sotres-Alvarez, Linda C. Gallo, Xiaonan Xue, Gregory A. Talavera, Kelly R. Evenson, Robert C. Kaplan, Kunihiro Matsushita, Jennifer A. Schrack
Summary: In Hispanic/Latino adults, having a low or high ABI is associated with lower and more fragmented physical activity. Individuals with low ABI tend to have more fragmented physical activity in the afternoon to evening.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Multidisciplinary Sciences
Lourdes R. R. Guerrero, Suzi Hong, Wassim Tarraf, Krista Perreira, Alvaro Camacho, Jordan N. N. Kohn, Daniel E. E. Jimenez, Gregory A. A. Talavera, Linda Gallo, Matthew A. A. Allison, Sylvia Wassertheil-Smoller, Hector M. M. Gonzalez
Summary: This study examined the association between anxiety and depressive symptoms with hsCRP levels in a diverse Hispanic/Latino population, and found a positive correlation between anxiety, depressive symptoms, and hsCRP levels. However, this association was not significant after considering cardiovascular disease risk factors and medications.
Article
Public, Environmental & Occupational Health
Catherine M. Pichardo, Earle C. Chambers, Lisa A. P. Sanchez-Johnsen, Margaret S. Pichardo, Linda Gallo, Gregory A. Talavera, Amber Pirzada, Amanda Roy, Sheila F. Castaneda, Ramon A. Durazo-Arvizu, Krista M. Perreira, Yanping Teng, Carmen B. Rodriguez, Matthew Allison, Jordan A. Carlson, Martha L. Daviglus, Jesse J. Plascak
Summary: This study found that neighborhood gentrification and income inequality change were not associated with the incidence of MetSyn among Hispanic/Latino adults.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Richard Kazibwe, Parag A. Chevli, Joni K. Evans, Matthew Allison, Erin D. Michos, Alexis C. Wood, Jingzhong Ding, Michael D. Shapiro, Morgana Mongraw-Chaffin
Summary: This study aimed to investigate the association between alcohol consumption and ectopic adiposity in adults at risk for cardiovascular disease. The results showed that heavy alcohol intake and binge drinking were associated with higher ectopic fat.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Kyndaron Reinier, Jee-Young Moon, Harpriya S. Chugh, Arayik Sargsyan, Kotoka Nakamura, Faye L. Norby, Audrey Uy-Evanado, Gregory A. Talavera, Linda C. Gallo, Martha L. Daviglus, Katy Hadduck, Daniel Shepherd, Angelo Salvucci, Robert C. Kaplan, Sumeet S. Chugh
Summary: This study provides population-based evidence on risk factors for sudden cardiac arrest (SCA) among Hispanic or Latino adults. It shows that chronic kidney disease is the strongest risk factor for SCA in this population, followed by established cardiovascular disease.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Oncology
Margaret S. Pichardo, Catherine M. Pichardo, Gregory A. Talavera, Linda C. Gallo, Charlene C. Kuo, Sheila F. Castaneda, Earle C. Chambers, Martha L. Daviglus, Amber Pirzada, Krista M. Perreira, Daniela Sotres-Alvarez, Tania Yadhira Pena Ortiz, Jesse J. Plascak
Summary: This study examines the association between neighborhood socioeconomic factors and cancer preventive behaviors, finding that neighborhood deprivation is negatively associated with adherence to cancer prevention guidelines while gentrification is positively associated with dietary recommendations.
CANCER RESEARCH COMMUNICATIONS
(2023)