Romidepsin targets multiple survival signaling pathways in malignant T cells

Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data

(2015) Susan E. Bates et al.   BRITISH JOURNAL OF HAEMATOLOGY

Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators

(2015) Benigno C. Valdez et al.   EXPERIMENTAL HEMATOLOGY

The TRAF3 adaptor protein drives proliferation of anaplastic large cell lymphoma cells by regulating multiple signaling pathways

(2014) Israel Muro et al.   CELL CYCLE

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

(2014) Katrina J. Falkenberg et al.   NATURE REVIEWS DRUG DISCOVERY

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Wnt/β-catenin pathway in ovarian cancer: A review

(2013) Rebecca C. Arend et al.   GYNECOLOGIC ONCOLOGY

Wnt Signaling in Normal and Malignant Hematopoiesis

(2013) W. Lento et al.   Cold Spring Harbor Perspectives in Biology

Romidepsin (FK228) and its analogs directly inhibit phosphatidylinositol 3-kinase activity and potently induce apoptosis as histone deacetylase/phosphatidylinositol 3-kinase dual inhibitors

(2012) Ken Saijo et al.   CANCER SCIENCE

The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB

(2012) Elisabeth Ziesché et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Histone Deacetylase in Cancer Cells Slows Down Replication Forks, Activates Dormant Origins, and Induces DNA Damage

(2010) Chiara Conti et al.   CANCER RESEARCH

Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide

(2010) Hideki Mizutani et al.   CANCER SCIENCE

Physiological Roles of Class I HDAC Complex and Histone Demethylase

(2010) Tomohiro Hayakawa et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Cladribine: not just another purine analogue?

(2009) Stephen Spurgeon et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Role of reactive oxygen species in proapoptotic ability of oncogenic H-Ras to increase human bladder cancer cell susceptibility to histone deacetylase inhibitor for caspase induction

(2009) Shambhunath Choudhary et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

5-Aza-2′-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis

(2009) Benigno C. Valdez et al.   LEUKEMIA RESEARCH

Romidepsin (depsipeptide) induced cell cycle arrest, apoptosis and histone hyperacetylation in lung carcinoma cells (A549) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression

(2007) Vinodhkumar Radhakrishnan et al.   BIOMEDICINE & PHARMACOTHERAPY