Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers

SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action

(2017) Mercedes Erburu et al.   NEUROPHARMACOLOGY

BDNF – a key transducer of antidepressant effects

(2016) Carl Björkholm et al.   NEUROPHARMACOLOGY

Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity

(2015) M. Erburu et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Spine synapse remodeling in the pathophysiology and treatment of depression

(2015) Catharine H. Duman et al.   NEUROSCIENCE LETTERS

Altered thalamocortical rhythmicity and connectivity in mice lacking CaV3.1 T-type Ca2+channels in unconsciousness

(2015) Soonwook Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

(2015) Tobias Rumpf et al.   Nature Communications

Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors

(2014) V Mangas-Sanjuan et al.   BRITISH JOURNAL OF PHARMACOLOGY

NEUROBIOLOGY OF STRESS, DEPRESSION, AND RAPID ACTING ANTIDEPRESSANTS: REMODELING SYNAPTIC CONNECTIONS

(2014) Ronald S. Duman   DEPRESSION AND ANXIETY

Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus

(2014) Jennifer D. Cooke et al.   PSYCHOPHARMACOLOGY

Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

(2014) Jesse S. O. Lindholm et al.   Frontiers in Behavioral Neuroscience

Ketamine and imipramine in the nucleus accumbens regulate histone deacetylation induced by maternal deprivation and are critical for associated behaviors

(2013) Gislaine Z. Réus et al.   BEHAVIOURAL BRAIN RESEARCH

Lysine deacetylases and mitochondrial dynamics in neurodegeneration

(2013) Pedro Guedes-Dias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

(2013) Roland W. Bürli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Association between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer’s disease in two independent European samples

(2013) Stefano Porcelli et al.   JOURNAL OF NEURAL TRANSMISSION

A Role for SIRT2-Dependent Histone H3K18 Deacetylation in Bacterial Infection

(2013) H. A. Eskandarian et al.   SCIENCE

Neurobiology of Major Depressive Disorder

(2013) Rosa Villanueva   NEURAL PLASTICITY

Design, Synthesis, and Biological Activity of a Novel Series of Human Sirtuin-2-Selective Inhibitors

(2012) Takayoshi Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

β-Adrenergic Receptor Stimulation and Activation of Protein Kinase A Protect Against α1-Adrenergic–Mediated Phosphorylation of Protein Kinase D and Histone Deacetylase 5

(2011) Carmen C. Sucharov et al.   JOURNAL OF CARDIAC FAILURE

Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: Effects of fluoxetine and MK-801

(2011) Séverine Farley et al.   NEUROPHARMACOLOGY

Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition

(2011) Herbert E. Covington et al.   NEUROSCIENCE LETTERS

New Therapeutic Targets for Mood Disorders

(2011) Rodrigo Machado-Vieira et al.   TheScientificWorldJOURNAL

Regulatory signal transduction pathways for class IIa histone deacetylases

(2010) Maribel Parra et al.   CURRENT OPINION IN PHARMACOLOGY

Clinical variations modulate patterns of gene expression and define blood biomarkers in major depression

(2010) Raoul Belzeaux et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Brain function and chromatin plasticity

(2010) Catherine Dulac   NATURE

Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex

(2010) E. Ampuero et al.   NEUROSCIENCE

Increased Vulnerability to Depressive-Like Behavior of Mice with Decreased Expression of VGLUT1

(2009) Alvaro L. Garcia-Garcia et al.   BIOLOGICAL PSYCHIATRY

Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia

(2009) Akihito Uezato et al.   BIPOLAR DISORDERS

Vesicular Glutamate Transporter VGLUT1 Has a Role in Hippocampal Long-Term Potentiation and Spatial Reversal Learning

(2009) D. Balschun et al.   CEREBRAL CORTEX

Altered gene expression of histone deacetylases in mood disorder patients

(2009) Teruyuki Hobara et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells

(2008) Lorena Donnici et al.   BMC NEUROSCIENCE

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

(2008) Ruwin Pandithage et al.   JOURNAL OF CELL BIOLOGY

Antipsychotics increase vesicular glutamate transporter 2 (VGLUT2) expression in thalamolimbic pathways

(2007) Larissa Moutsimilli et al.   NEUROPHARMACOLOGY