Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome

Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model

(2012) Inge Heulens et al.   BEHAVIOURAL BRAIN RESEARCH

Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma

(2012) Thomas A. Lanz et al.   BIOMARKERS

Reduction of BDNF expression inFmr1knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits

(2012) M. Uutela et al.   GENES BRAIN AND BEHAVIOR

Expressions of Brain-Derived Neurotrophic Factor (BDNF) in Cerebrospinal Fluid and Plasma of Children With Meningitis and Encephalitis/Encephalopathy

(2012) Shinichiro Morichi et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

The Therapeutic effect of Memantine through the Stimulation of Synapse Formation and Dendritic Spine Maturation in Autism and Fragile X Syndrome

(2012) Hongen Wei et al.   PLoS One

Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test

(2012) Agnieszka Pałucha-Poniewiera et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen

(2012) C. Henderson et al.   Science Translational Medicine

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

The GABAA Receptor Agonist THIP Ameliorates Specific Behavioral Deficits in the Mouse Model of Fragile X Syndrome

(2011) Jose Luis Olmos-Serrano et al.   DEVELOPMENTAL NEUROSCIENCE

An Open-Label Naturalistic Pilot Study of Acamprosate in Youth with Autistic Disorder

(2011) Craig A. Erickson et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Downregulation of GABAA β Subunits is Transcriptionally Controlled by Fmr1p

(2011) Andrew Hong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Restraint stress and repeated corticotrophin-releasing factor receptor activation in the amygdala both increase amyloid-β precursor protein and amyloid-β peptide but have divergent effects on brain-derived neurotrophic factor and pre-synaptic proteins in the prefrontal cortex of rats

(2011) B. Ray et al.   NEUROSCIENCE

Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker

(2011) Balmiki Ray et al.   PLoS One

Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

(2011) S. Jacquemont et al.   Science Translational Medicine

Blood BDNF concentrations reflect brain-tissue BDNF levels across species

(2010) Anders B. Klein et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

(2010) J. L. Olmos-Serrano et al.   JOURNAL OF NEUROSCIENCE

BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse

(2010) Verna Louhivuori et al.   NEUROBIOLOGY OF DISEASE

Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

(2010) Heath D Schmidt et al.   NEUROPSYCHOPHARMACOLOGY

Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology

(2009) Anilkumar Pillai et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome

(2009) E Berry-Kravis et al.   JOURNAL OF MEDICAL GENETICS

Acamprosate: Recent Findings and Future Research Directions

(2008) Karl Mann et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of Acamprosate on Neuronal Receptors and Ion Channels Expressed inXenopusOocytes

(2008) Matthew T. Reilly et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Co-occurring conditions associated withFMR1gene variations: Findings from a national parent survey

(2008) Donald B. Bailey et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments

(2008) Darrick T. Balu et al.   BRAIN RESEARCH

The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats

(2008) Jolanta Kotlinska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions

(2008) Yuri A. Blednov et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

(2008) Gül Dölen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

(2008) Femke M.S. de Vrij et al.   NEUROBIOLOGY OF DISEASE