LY2033298, a positive allosteric modulator at muscarinic M4 receptors, enhances inhibition by oxotremorine of light-induced phase shifts in hamster circadian activity rhythms

Sleep–wake cycles and cognitive functioning in schizophrenia

(2011) Vivien Bromundt et al.   BRITISH JOURNAL OF PSYCHIATRY

Daily variations in sleep–wake patterns and severity of psychopathology: A pilot study in community-dwelling individuals with chronic schizophrenia

(2011) Flavie Waters et al.   PSYCHIATRY RESEARCH

Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague–Dawley rats

(2011) Amir H. Rezvani et al.   PSYCHOPHARMACOLOGY

The cholinergic system, circadian rhythmicity, and time memory

(2010) R.A. Hut et al.   BEHAVIOURAL BRAIN RESEARCH

Impact of species variability and ‘probe-dependence’ on the detection and in vivo validation of allosteric modulation at the M4 muscarinic acetylcholine receptor

(2010) S Suratman et al.   BRITISH JOURNAL OF PHARMACOLOGY

The antipsychotic potential of muscarinic allosteric modulation

(2010) T.M. Bridges et al.   DRUG NEWS & PERSPECTIVES

Cholinergic Modulation of Neuronal Excitability in the Rat Suprachiasmatic Nucleus

(2010) Jyh-Jeen Yang et al.   JOURNAL OF NEUROPHYSIOLOGY

Allosteric activators of muscarinic receptors as novel approaches for treatment of CNS disorders

(2010) Gregory J. Digby et al.   Molecular BioSystems

Neurochemical basis for symptomatic treatment of Alzheimer's disease

(2010) Paul T. Francis et al.   NEUROPHARMACOLOGY

Effects of oxotremorine and physostigmine on the inhibitory avoidance impairment produced by amitriptyline in male and female mice

(2009) Santiago Monleón et al.   BEHAVIOURAL BRAIN RESEARCH

Differential influence of selective 5-HT5A vs 5-HT1A, 5-HT1B, or 5-HT2C receptor blockade upon light-induced phase shifts in circadian activity rhythms: Interaction studies with citalopram

(2009) Robert L. Gannon et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Sleep, activity, temperature and arousal responses of mice deficient for muscarinic receptor M2 or M4

(2009) Jeremy Turner et al.   LIFE SCIENCES

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

(2009) Katie Leach et al.   NEUROPSYCHOPHARMACOLOGY

Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

(2009) P. Jeffrey Conn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Combined Scopolamine and Ethanol Treatment Results in a Locomotor Stimulant Response Suggestive of Synergism That is Not Blocked by Dopamine Receptor Antagonists

(2008) Angela C. Scibelli et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice

(2008) Marie L. Woolley et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Circadian rhythm disturbances in depression

(2008) Anne Germain et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Muscarinic-2 and orexin-2 receptors on GABAergic and other neurons in the rat mesopontine tegmentum and their potential role in sleep-wake state control

(2008) Frédéric Brischoux et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Muscarinic receptors: do they have a role in the pathology and treatment of schizophrenia?

(2008) Elizabeth Scarr et al.   JOURNAL OF NEUROCHEMISTRY

Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats

(2008) A. E. Brady et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis

(2008) Stefan Leucht et al.   LANCET

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

(2008) W. Y. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Muscarinic acetylcholine receptors as CNS drug targets

(2007) Christopher J. Langmead et al.   PHARMACOLOGY & THERAPEUTICS