Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

Orexin Receptors: Pharmacology and Therapeutic Opportunities

(2011) Thomas E. Scammell et al.   Annual Review of Pharmacology and Toxicology

Waking at night to smoke as a marker for tobacco dependence: patient characteristics and relationship to treatment outcome

(2010) M. T. Bover et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanol–preferring Sprague–Dawley rats

(2009) David E. Moorman et al.   ALCOHOL

Reinstatement of Cocaine Seeking by Hypocretin (Orexin) in the Ventral Tegmental Area: Independence from the Local Corticotropin-Releasing Factor Network

(2009) Bin Wang et al.   BIOLOGICAL PSYCHIATRY

Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking

(2009) Rachel J. Smith et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system

(2009) Rodrigo A. España et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ethanol- and cocaine-induced locomotion are genetically related to increases in accumbal dopamine

(2009) Paul J. Meyer et al.   GENES BRAIN AND BEHAVIOR

Orexin A/Hypocretin-1 Selectively Promotes Motivation for Positive Reinforcers

(2009) S. L. Borgland et al.   JOURNAL OF NEUROSCIENCE

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

(2009) C. Dugovic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antagonists

(2009) P. Malherbe et al.   MOLECULAR PHARMACOLOGY

Electrophysiological effects of orexin/hypocretin on nucleus accumbens shell neurons in rats: An in vitro study

(2009) Katsuyuki Mukai et al.   PEPTIDES

Orexin Mediates the Expression of Precipitated Morphine Withdrawal and Concurrent Activation of the Nucleus Accumbens Shell

(2008) Ruth Sharf et al.   BIOLOGICAL PSYCHIATRY

Differential effects of the hypocretin 1 receptor antagonist SB 334867 on high-fat food self-administration and reinstatement of food seeking in rats

(2008) S G Nair et al.   BRITISH JOURNAL OF PHARMACOLOGY

Orexin B/hypocretin 2 increases glutamatergic transmission to ventral tegmental area neurons

(2008) S. L. Borgland et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Distinct subsets of nucleus accumbens neurons encode operant responding for ethanol versus water

(2008) Donita L. Robinson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers

(2008) S. Otmani et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Role of lateral hypothalamic orexin neurons in reward processing and addiction

(2008) Gary Aston-Jones et al.   NEUROPHARMACOLOGY

Smoking during the night: Prevalence and smoker characteristics

(2008) Deborah Scharf et al.   NICOTINE & TOBACCO RESEARCH

Sleep deprivation increases cigarette smoking

(2008) Ajna Hamidovic et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Insular hypocretin transmission regulates nicotine reward

(2008) J. A. Hollander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long–Evans rats

(2008) Jemma K. Richards et al.   PSYCHOPHARMACOLOGY

Quetiapine in the Treatment of Sleep Disturbances Associated with Addictive Conditions: A Retrospective Study

(2008) Antonio Terán et al.   SUBSTANCE USE & MISUSE

Orexin neuronal circuitry: Role in the regulation of sleep and wakefulness

(2007) Kousaku Ohno et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The orexin system regulates alcohol-seeking in rats

(2006) Andrew J Lawrence et al.   BRITISH JOURNAL OF PHARMACOLOGY