Article
Clinical Neurology
J. Lumikukka Socada, John J. Soderholm, Tom Rosenstrom, Jesper Ekelund, Erkki Isometsa
Summary: This study investigated the prevalence, severity, co-occurrence, and overlap of manic symptoms and borderline personality features in unipolar and bipolar major depressive episodes. The results showed that the presence of mixed and borderline features in MDEs is common, with differences in diagnosis-specific features among different subcohorts. The study highlighted the impact of hypomania on perceived BPD features and the correlation between manic symptoms and borderline features.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Kelly S. Chen, Yogesh Dwivedi, Richard C. Shelton
Summary: This study suggests that intravenous ketamine is effective in patients with major depressive disorder, both with and without elevated borderline features. This provides reassurance for clinicians regarding the use of ketamine in this population.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
John J. Soderholm, J. Lumikukka Socada, Tom Rosenstrom, Jesper Ekelund, Erkki Isometsa
Summary: The course of illness differs between MDD, BD, and BPD patients. Bipolar depressive patients have an alternating course and the shortest time to first remission. The severity of BPD may predict the duration of remission from depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Clinical Neurology
Alessandro Ceresa, Cecilia Maria Esposito, Massimiliano Buoli
Summary: When BPD coexists with MDD, treatment response is generally poorer, making clinical management challenging. The combination of SSRI and psychotherapy may be an effective treatment option, with further research needed to confirm these findings.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Victor De la Pena-Arteaga, Mercedes Berruga-Sanchez, Trevor Steward, Ignacio Martinez-Zalacain, Ximena Goldberg, Agustina Wainsztein, Carolina Abulafia, Narcis Cardoner, Mariana N. Castro, Mirta Villarreal, Jose M. Menchon, Salvador M. Guinjoan, Carles Soriano-Mas
Summary: This study identified a shared neurobiological contributor to emotion regulation deficits in MDD and BPD characterized by decreased vlPFC activity, while also observing disorder-specific alterations. In MDD, there is a primary deficit in prefrontal activations, while BPD is defined by connectivity disruptions between the vlPFC and temporal emotion processing regions. These findings substantiate the different profiles of emotion regulation alterations observed in these disorders in neurobiological terms.
EUROPEAN PSYCHIATRY
(2021)
Article
Psychology, Clinical
Ping Tong, Ping Bo, Yuanhong Shi, Liping Dong, Ting Sun, Xia Gao, Yang Yang
Summary: Patients with major depressive disorder (MDD) comorbid with borderline personality disorder (BPD) have earlier onset, higher levels of anxiety symptoms, impulsive behavior, and non-suicidal self-harm frequency compared to patients with MDD only. These findings suggest that patients with impulsive behavior in MDD may have comorbid BPD.
DEPRESSION AND ANXIETY
(2021)
Article
Psychology, Clinical
Jessica R. Peters, Michael L. Crowe, Theresa Morgan, Mark Zimmerman, Carla Sharp, Carlos M. Grilo, Charles A. Sanislow, M. Tracie Shea, Mary C. Zanarini, Thomas H. McGlashan, Leslie C. Morey, Andrew E. Skodol, Shirley Yen
Summary: This study examined the stability and centrality of BPD symptom networks across samples varying in age and clinical characteristics. The results showed that the BPD symptom networks were largely similar and strongly correlated across the samples. Affective instability and identity disturbance were identified as relatively central symptoms in all samples, with relationship difficulties being central in the adult networks. Differences in network attributes were more evident between networks varying both in age and in BPD symptom severity level.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Liliana Dell'Osso, Benedetta Nardi, Chiara Bonelli, Davide Gravina, Francesca Benedetti, Giulia Amatori, Simone Battaglini, Gabriele Massimetti, Mario Luciano, Isabella Berardelli, Natascia Brondino, Marianna De Gregorio, Giacomo Deste, Marta Nola, Antonino Reitano, Maria Rosaria Anna Muscatello, Maurizio Pompili, Pierluigi Politi, Antonio Vita, Claudia Carmassi, Ivan Mirko Cremone, Barbara Carpita, Mario Maj
Summary: Recent research has found that catatonia is more common among psychiatric patients than previously thought, especially among those with autism spectrum disorders, mood disorders, and borderline personality disorder. These conditions are all associated with an increased risk of suicide. This study aimed to evaluate how the presence and prevalence of catatonic symptoms correlate with suicidal risk in individuals with major depressive disorder or borderline personality disorder. The results showed that higher catatonic traits were linked to higher suicidal tendencies, but the patterns of association differed between the two disorders.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Clinical
Timothy A. Allen, Michael N. Hallquist, Aidan G. C. Wright, Alexandre Y. Dombrovski
Summary: This longitudinal study examined the potential moderating effects of personality traits on the link between interpersonal dysfunction and suicidal behavior in individuals diagnosed with borderline personality disorder. The results suggested that negative affectivity and disinhibition played significant roles in the association between interpersonal dysfunction, suicidal ideation, and suicide attempts.
CLINICAL PSYCHOLOGICAL SCIENCE
(2022)
Article
Psychiatry
Joseph Maffly-Kipp, Morgan N. McCredie, Leslie C. Morey
Summary: This study aimed to investigate the impact of identity disturbance on the Self-Reference Effect (SRE). The results showed that there was a correlation between recall and identity disturbance in the self-reference condition, but it was not significant. This suggests the need for further research using multimethod approaches to personality pathology, particularly in clinical populations.
BORDERLINE PERSONALITY DISORDER AND EMOTION DYSREGULATION
(2022)
Article
Clinical Neurology
Yuan Cao, Hongsheng Xie, Huan Sun, Hongqi Xiao, Xipeng Long, Changjian Qiu, Zhiyun Jia
Summary: A meta-analysis was conducted to explore the common and distinct gray matter volume (GMV) alterations in young adults with borderline personality disorder (BPD) and major depressive disorder (MDD). Results showed that BPD was associated with GMV reduction in the prefrontal cortex, medial temporal network, and insula, while MDD was associated with GMV alteration in the visual and sensorimotor networks. Differences in GMV between the two disorders were observed in the orbitofrontal cortex, cingulate cortex, insula, and cerebellum.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Article
Health Care Sciences & Services
Judit Szalai
Summary: This paper examines the potential of AI-based addendum therapy for borderline personality disorder, suggesting that AI assistance could help enhance self-narratives coherence by improving accuracy of self-assessments and reflection on emotions, complementing human-to-human therapy. Theoretical and pragmatic arguments are presented in favor of this idea, along with suggested technical solutions for implementation.
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
(2021)
Article
Clinical Neurology
Guohong Xu, Xiaoling Li, Caixia Xu, Guojun Xie, Jiaquan Liang
Summary: This study aimed to assess the impact of insomnia on the prognosis of patients with major depressive disorder (MDD), finding that insomnia may lead to poor treatment outcomes for patients with MDD and should be taken seriously.
Review
Medicine, General & Internal
Tina Wu, Jennifer Hu, Dimitry Davydow, Heather Huang, Margaret Spottswood, Hsiang Huang
Summary: Borderline personality disorder is a common mental health diagnosis observed in the primary care population and is associated with various challenges in diagnosis and treatment. This article aims to describe the impact of BPD in primary care, review current knowledge, and provide evidence-based treatment approaches for these patients.
FRONTIERS IN MEDICINE
(2022)
Article
Psychology, Multidisciplinary
Bo Peng, Jiwu Liao, Yang Li, Guangbo Jia, Jihui Yang, Zhiwei Wu, Jian Zhang, Yingjia Yang, Xinxin Luo, Yao Wang, Yingli Zhang, Jiyang Pan
Summary: This study aimed to investigate the differences in personality traits, defensive styles, and borderline symptoms among first-episode youth patients with depression and self-injury. The results showed that patients with depression and self-injury had higher levels of psychoticism and intermediate defense styles. The frequency of self-injury was negatively correlated with mature defense styles and positively correlated with depressive symptoms and borderline symptoms. Psychoticism and depressive symptoms were identified as independent risk factors for predicting non-suicidal self-injury in patients with depression.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychology, Clinical
Jenna M. Traynor, Johannes S. Wrege, Marc Walter, Anthony C. Ruocco
Summary: This study found disruptions in functional connectivity in core mentalization and affective networks in patients with personality disorders, suggesting that increased intralimbic functional connectivity may contribute to self-interpersonal impairment regardless of specific PD symptoms.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Christoph Kasinger, Danielle Otten, Yve Stoebel-Richter, Manfred E. Beutel, Markus Zenger, Elmar Braehler, Hendrik Berth
Summary: Utilizing data from a longitudinal study in Saxony, the study compared the psychological distress between internal migrants and non-migrants through bootstrapping-based mediation analysis. The results showed that internal migrants reported less mental distress in 2010, but not in 2020, and various factors such as life situations, political solidarity, job security, and threats of old-age poverty played crucial roles in influencing the mental health of internal migrants.
PSYCHOTHERAPIE PSYCHOSOMATIK MEDIZINISCHE PSYCHOLOGIE
(2022)
Article
Biology
Alexander Zinke, Christin Bohl, Hendrik Berth
Summary: The objective of this study was to identify anxiety and psychological distress levels in dental patients using the Dental Anxiety Scale and the Brief Symptom Inventory-18, and to explore their correlations with gender and age. The dataset includes questionnaire responses from 1550 patients and can provide references for future research.
BMC RESEARCH NOTES
(2022)
Article
Psychiatry
Maximilian Meyer, Bernd Rist, Johannes Strasser, Undine E. Lang, Marc Vogel, Kenneth M. Dursteler, Marc Walter
Summary: The study found that patients with a history of incarcerations during heroin-assisted treatment were mainly incarcerated due to cocaine use, impaired functioning, and financial constraints. These factors often co-occurred and contributed to the likelihood of incarceration. Many patients were imprisoned primarily because they were unable to pay fines resulting from minor offenses.
Review
Psychiatry
Patrick Koeck, Maximilian Meyer, Julie Elsner, Kenneth M. Duersteler, Marc Vogel, Marc Walter
Summary: Adolescence and emerging adulthood, known as youth, are vulnerable to substance use disorders and co-occurring mental health disorders. These comorbidities have significant impact on the development and course of substance use disorders in transitional-aged youth. However, data on this population is highly inconsistent. Universal screening and treatment guidelines should be aimed for in the future.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Mario Mueller, Nathalie Brackmann, Matthias Jaeger, Anastasia Theodoridou, Stefan Vetter, Erich Seifritz, Florian Hotzy
Summary: This study aims to fill the gap in knowledge by evaluating the course of coercion during psychiatric inpatient treatment and identifying risk factors associated with coercion. The use of coercive measures is more frequent in the early stages of treatment, particularly for patients with manic or psychotic episodes, involuntary admission, and chronicity and clinical severity.
EUROPEAN PSYCHIATRY
(2023)
Article
Environmental Sciences
Kristine Khachatryan, Manfred E. Beutel, Yve Stoebel-Richter, Markus Zenger, Hendrik Berth, Elmar Braehler, Peter Schmidt
Summary: This study investigated the relationship between an individual's psychological distress, subjective physical health, and attitudes towards the COVID-19 pandemic, finding that psychological distress and subjective physical health have different impacts on attitudes towards the pandemic.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Psychology, Clinical
Franziska Klimt, Elmar Braehler, Yve Stoebel-Richter, Markus Zenger, Hendrik Berth
Summary: This study evaluates a potential single-item screening instrument for sleep disturbances and confirms its good psychometric properties and brevity. It contributes to the early detection of sleep disturbances.
PSYCHOTHERAPIE PSYCHOSOMATIK MEDIZINISCHE PSYCHOLOGIE
(2023)
Article
Obstetrics & Gynecology
Silke Ingrisch, Hendrik Berth, Wolfram Schulze
Summary: This study investigated the current practice of psychosocial care for parents in perinatal infant death in German hospitals. The researchers found that hospital size positively influenced the number of services provided to bereaved parents, and the number of services provided to hospital staff positively influenced the number of informational services provided to bereaved parents.
ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE
(2023)
Article
Clinical Neurology
Franziska Klimt, Clara Jacobi, Elmar Braehler, Yve Stoebel-Richter, Markus Zenger, Hendrik Berth
Summary: This study analyzed the self-reported insomnia symptoms of the general population over more than 20 years and found that insomnia symptoms increase with age. The study also found no significant gender differences in the prevalence rates of insomnia symptoms.
Article
Medicine, General & Internal
Christian H. Winkler, Monika Bjelopavlovic, Karl M. Lehmann, Katja Petrowski, Lisa Irmscher, Hendrik Berth
Summary: This study aimed to explore the impact of dental anxiety on dental care habits and oral-health-related quality of life in adults. By using the Dental Anxiety Scale (DAS) and the German Oral Health Impact Profile (OHIP-G5), the extent of dental anxiety was assessed. The findings revealed a significant correlation between elevated dental anxiety scores and reduced frequency of tooth brushing, calculus removal, and dental cleaning appointments. However, the use of dental floss, mouthwash, and toothbrush hardness were not significantly affected. Additionally, individuals with dental anxiety preferred manual toothbrushes over electric ones, and higher dental anxiety scores were strongly associated with a decline in overall oral health-related quality of life.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Dina Zota, Dimitrios V. Diamantis, Konstantinos Katsas, Pania Karnaki, Thomas Tsiampalis, Piotr Sakowski, Costas A. Christophi, Eleni Ioannidou, Sara Darias-Curvo, Victoria-Luise Batury, Hendrik Berth, Anja Zscheppang, Maike Linke, Sotiris Themistokleous, Afroditi Veloudaki, Athena Linos
Summary: This study aimed to evaluate healthcare professionals' perception of the necessity, barriers, facilitators, and critical skills in health communication. The findings showed that only 57% of participants had received health communication training, but 88.1% of them expressed a willingness to be trained. Most participants considered communication skills, barriers, facilitators, and outcomes important for successful health communication, with nurses giving them higher importance than physicians.
Article
Substance Abuse
Monika Mueller, Edith Paula Meszaros, Marc Walter, Lavinia Baltes-Flueckiger, Marcus Herdener, Reto Auer, Gabriel Thorens, Stephane Rothen, Carlos Nordt, Daniele Zullino
Summary: This study examined the acceptability of twelve different regulatory aspects by cannabis users, including those obtaining cannabis from the illicit market and vulnerable populations. The results showed that THC content regulation was the most contentious aspect, with a majority of participants stating a preference for a regulated program if five different THC contents were available, compared to only 54% if only 12% THC was available. Disposal of contact details was the least accepted aspect. Participants obtaining cannabis from the illicit market were more likely to engage in a regulated program. Therefore, a carefully designed program that considers the consumers' perspective is necessary to engage the target population.
EUROPEAN ADDICTION RESEARCH
(2023)
Article
Clinical Neurology
Anna-Chiara Schaub, Marc Vogel, Sophie Baumgartner, Undine E. Lang, Stefan Borgwardt, Andre Schmidt, Marc Walter
Summary: This study reports functional brain changes in patients receiving long-term diacetylmorphine treatment. The study found that fronto-striatal resting-state functional connectivity increased in patients compared to healthy controls, and this effect was partly related to the treatment duration.
BRAIN COMMUNICATIONS
(2022)
Article
Substance Abuse
Marc Vogel, Patrick Kock, Johannes Strasser, Christoph Kalbermatten, Hannes Binder, Kenneth M. Dursteler, Marc Walter, Luis Falcato, Michael Krausz, Adrian Kormann
Summary: The study presents a case series of 3 patients who successfully switched from i-HAT to n-HAT. Nasal DAM may be an important risk-reduced rapid-onset alternative to i-HAT, particularly suitable for patients with injection-related complications or noninjecting opioid-dependent patients failing to respond to oral OAT.
EUROPEAN ADDICTION RESEARCH
(2022)