Article
Chemistry, Physical
Shuang-Qiao Sun, Cheng Liu, Min Zhu, Yan-Lin Xu, Wei He, Dan-Dan Feng, Chen-Chao Huang, Qi Sun, Yue-Min Xie, You-Yong Li, Man-Keung Fung
Summary: This study reveals the influence of electrical bias on the spectral stability and efficiency roll-off of mixed-halide PeLEDs and identifies several key factors, including electric-field induced Joule heating, pinhole formation under electrical bias, and halogen ion migration. Furthermore, the study substantiates that chloride ion migration plays a more dominant role in device degradation.
MATERIALS TODAY ENERGY
(2022)
Article
Chemistry, Multidisciplinary
Feiyu Yang, Pengcheng Chen, Han Jiang, Tianfa Xie, Yue Shao, Deok-Ho Kim, Bo Li, Yubing Sun
Summary: Strain gradients play a crucial role in directional cell migration. This study develops a programmable uniaxial cell stretch device to create controllable strain gradients and demonstrates that these gradients are sufficient to drive over 60% of rat embryonic fibroblasts towards the lower strain side. Focal adhesion analysis and a motor-clutch model suggest that strain-introduced traction force and integrin fibronectin pairs' catch-release dynamics are responsible for such directional migration.
Review
Polymer Science
Chen-Xi Tu, Chang-You Gao
Summary: The surfaces and interfaces of biomaterials play a crucial role in influencing biological systems, and surface modification is an effective method to control selective cell adhesion and migration for desired cell-biomaterial interactions. Recent advances in surface modification techniques have allowed for the manipulation of cell behaviors on biomaterials in complex environments, leading to improved tissue repair and regeneration.
CHINESE JOURNAL OF POLYMER SCIENCE
(2021)
Article
Multidisciplinary Sciences
Kazusato Oikawa, Shino Goto-Yamada, Yasuko Hayashi, Daisuke Takahashi, Yoshitaka Kimori, Michitaro Shibata, Kohki Yoshimoto, Atsushi Takemiya, Maki Kondo, Kazumi Hikino, Akira Kato, Keisuke Shimoda, Haruko Ueda, Matsuo Uemura, Keiji Numata, Yoshinori Ohsumi, Ikuko Hara-Nishimura, Shoji Mano, Kenji Yamada, Mikio Nishimura
Summary: Pexophagy plays a pivotal role in selectively removing ROS-generating peroxisomes under high-intensity light, which protects plants from oxidative damage during photosynthesis.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Siqi Zhou, Ryusuke Yamada, Kazuichi Sakamoto
Summary: Visible light is present everywhere in our lives, and the increased use of computers and smartphones has led to more time spent in front of screens. Recent studies have shown that short-wavelength blue light can have negative effects on cells, inhibiting their proliferation and promoting oxidative stress and apoptosis. This experiment studied the effects of longer wavelength and lower energy density blue light on cells, and found that it still inhibits cell growth and metastatic capability, promotes reactive oxygen species and DNA damage, and increases melanin synthesis. These results highlight the importance of controlling daily digital device use.
Article
Physics, Applied
Dan Liraz, Pei Cheng, Yang Yang, Nir Tessler
Summary: Revisiting the intensity-dependent quantum efficiency (IDQE) technique in the context of non-fullerene acceptors, this study finds anomalous behavior at forward-bias conditions that is not consistent with light excitation induced trap filling. Analysis based on the Shockley-Read-Hall model suggests that the contacts cause the traps to be completely full in the dark, and light excitation half-empties the traps, leading to the anomalous behavior. Fitting the IDQE at different bias levels reveals trapping consistent with multiphonon capture by a state close to the middle of the gap. Monitoring trap-assisted recombination is essential for indoor applications and surpassing the 20% power conversion efficiency limit of single junctions.
JOURNAL OF APPLIED PHYSICS
(2022)
Article
Biology
Nagarajan Theruveethi, Bang Viet Bui, Manjunath B. Joshi, Manna Valiathan, Shonraj Ballae Ganeshrao, Sivakumar Gopalakrishnan, Shama Prasada Kabekkodu, Shailaja S. Bhat, Sudarshan Surendran
Summary: Blue light exposure can cause retinal damage and changes in visual cortex neurons, while blue light-blocking lenses can alleviate these damages.
Article
Biochemistry & Molecular Biology
Keiichi Hiramoto, Sayaka Kubo, Keiko Tsuji, Daijiro Sugiyama, Hideo Hamano
Summary: In this study, the effect of long-term blue light exposure on the induction of skin cancer was investigated. It was found that skin cancer was induced only in mice exposed to blue light, and blue light exposure also increased the migration of neutrophils and macrophages involved in carcinogenesis. These findings suggest that long-term exposure to blue light can induce neutrophil NETosis and an increase in type 1 macrophages, leading to skin cancer.
Article
Plant Sciences
Jun Liu, Marc W. van Iersel
Summary: The study demonstrates that green light has lower photosynthetic efficiency at low light intensity, while it may have higher efficiency at high light intensity compared to red and blue light, due to its more uniform absorption throughout the leaves.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Shun-Ling Tan, Jia-Lin Huang, Feng-Ping Zhang, Shi-Bao Zhang, Wei Huang
Summary: This study revealed that low-light phases significantly affect the extent of PSI photoinhibition in fluctuating light conditions, with a higher light intensity inducing a higher proton gradient across thylakoid membranes. The activation of cyclic electron flow (CEF) is finely regulated to optimize the balance between photoprotection and light use efficiency in fluctuating light environments. Additionally, CEF activation in high-light phases is highly dependent on the PSI reduction state.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Article
Nanoscience & Nanotechnology
Manoj K. Jamarkattel, Xavier Mathew, Adam B. Phillips, Ebin Bastola, Kamala Khanal Subedi, Fadhil K. Alfadhili, Abasi Abudulimu, Jared D. Friedl, Rasha A. Awni, Deng-Bing Li, Mohammed A. Razooqi, Prakash Koirala, Robert W. Collins, Yanfa Yan, Randy J. Ellingson, Michael J. Heben
Summary: The performance of CdTe solar cells has significantly improved in recent years with the incorporation of Se. However, the instabilities in Cu-doped Se-alloyed CdTe devices are less explored. In this study, a range of CdSe/CdTe solar cells were fabricated and analyzed, and it was found that devices fabricated with a 120 nm CdSe layer thickness showed a dramatic improvement in efficiency after light soaking.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Plant Sciences
Jianing Han, Tong Li, Xuelian Wang, Xi Zhang, Xiaoning Bai, Huihui Shao, Shaojie Wang, Zenghui Hu, Jing Wu, Pingsheng Leng
Summary: Blue light enhances the production of floral terpenoid volatiles in snapdragon, and this response is mediated by the transcription factor AmMYB24 and the signal receptor AmCRY1.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Optics
Taotao Zhang, Rui Xu, Hang Lv, Zhenxiang Wang, Haidong Ye, Haiqin Liu, Liang Chen
Summary: Researchers successfully constructed blue light-emitting electrochemical cells using aggregation-induced emission small molecules, demonstrating high luminance and efficiency. This opens up a new research avenue for the application of AIE materials in the field of thin-film device development.
Article
Cell Biology
Thomas Quast, Karolin Zoelzer, Donald Guu, Luis Alvarez, Carsten Kuesters, Eva Kiermaier, U. Benjamin Kaupp, Waldemar Kolanus
Summary: This study used a combination of microfluidics and quantitative in vitro live cell imaging to investigate the chemotactic sensing strategy of dendritic cells (DCs). The results showed that spatial sensing mechanisms are essential for the persistent chemotaxis of DCs in stable gradients.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Oncology
Miriam Palmiero, Isabel Cantarosso, Laura di Blasio, Valentina Monica, Barbara Peracino, Luca Primo, Alberto Puliafito
Summary: Cancer cells can migrate collectively and form heteroclonal cell clusters through subcellular actin-rich protrusions. Disruption of cytoskeletal dynamics impairs collective migration, while myosin II activation is necessary for multicellular movements. The attraction of cell clusters may be mediated by secreted soluble factors, as evidenced by inhibition experiments and the chemoattracting activity of conditioned culture media.
MOLECULAR ONCOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Y-C Kao, J-R Jheng, H-J Pan, W-Y Liao, C-H Lee, P-L Kuo
Article
Immunology
Bing-Mae Chen, Mohammad Ameen Al-Aghbar, Chien-Hsin Lee, Tien-Ching Chang, Yu-Cheng Su, Ya-Chen Li, Shih-En Chang, Chin-Chuan Chen, Tsai-Hua Chung, Yuan-Chun Liao, Chau-Hwang Lee, Steve R. Roffler
FRONTIERS IN IMMUNOLOGY
(2017)
Article
Chemistry, Multidisciplinary
Chia-Wei Lee, Ya-Ling Chiang, Ji-Ting Liu, Yi-Xian Chen, Chau-Hwang Lee, Yeng-Long Chen, Ing-Shouh Hwang
Article
Multidisciplinary Sciences
Chao-Hung Chang, Hsiao-Hui Lee, Chau-Hwang Lee
SCIENTIFIC REPORTS
(2017)
Article
Multidisciplinary Sciences
Yu-Chiu Kao, Yu-Cing Liao, Pei-Lin Cheng, Chau-Hwang Lee
SCIENTIFIC REPORTS
(2019)
Article
Oncology
Hsin-Han Hou, Huei-Jyuan Pan, Wei-Yu Liao, Chau-Hwang Lee, Chong-Jen Yu
INTERNATIONAL JOURNAL OF CANCER
(2020)
Article
Biochemistry & Molecular Biology
Yu-Chiu Kao, Zih-Hua Chen, Wen-Yu Wang, Chau-Hwang Lee, Po-Ling Kuo
Summary: Elevated hydrostatic pressure can significantly accelerate fibroblast migration, which is dependent on the increase of transforming growth factor-beta (1) and the activation of filamin A. The results suggest that interstitial HP elevation associated with various pathological states could significantly regulate fibroblast migration.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Cell Biology
Chia-Wei Lee, Chia-Chen Kuo, Chi-Jung Liang, Huei-Jyuan Pan, Chia-Ning Shen, Chau-Hwang Lee
Summary: This study reveals the influence of macrophages on tunneling nanotube (TNT) formation in cancer cells. The formation of TNTs is correlated with increased motility, invasion, and epithelial-mesenchymal transition in cancer cells. Moreover, mitochondria and lysosomes can be transported through TNTs.
BMC MOLECULAR AND CELL BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Yu-Chiu Kao, Guan-Yun Lin, Ji-Yen Cheng, Chau-Hwang Lee
Summary: Research has shown that red light with wavelengths of 620 nm and 760 nm can enhance neurite growth, while red light with a wavelength of 680 nm has no effect. The growth of neurites is accompanied by an increase in intracellular reactive oxygen species (ROS), and reducing ROS levels hinders red light-induced neurite growth. Inhibition of cytochrome c oxidase (CCO) activity also hinders red light-induced neurite growth, suggesting that ROS production through the activation of CCO is beneficial for neurite growth.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2023)
Article
Engineering, Biomedical
Huei-Jyuan Pan, Chia-Wei Lee, Li-Yu Wu, Heng-Hua Hsu, Yi-Chung Tung, Wei-Yu Liao, Chau-Hwang Lee
Summary: Fibrosis and fibroblast activation commonly occur in the tissues surrounding tumors, and anti-fibrotic drugs are used alongside chemotherapy to counteract these effects. This study developed a three-dimensional co-culture system using fibroblasts and lung cancer cell spheroids to mimic the tumor microenvironment. The efficacy of an anticancer drug, cisplatin, was compared with and without pretreatment of two anti-fibrotic drugs, nintedanib and pirfenidone, on cancer cell growth and invasion. The results showed that nintedanib enhanced cisplatin's effects, while pirfenidone did not. This study demonstrates the usefulness of the 3D co-culture system in evaluating the effects of drug combinations on tumor growth and invasion.
APL BIOENGINEERING
(2023)
Review
Physics, Multidisciplinary
Chia-Wei Lee, Chun-Chieh Wang, Chau-Hwang Lee
ADVANCES IN PHYSICS-X
(2017)
