Article
Psychology, Multidisciplinary
Jian Bai, Longjie Gu, Yinwei Chen, Xiaming Liu, Jun Yang, Mingchao Li, Xiyuan Dong, Shulin Yang, Bo Huang, Tao Wang, Lei Jin, Jihong Liu, Shaogang Wang
Summary: This study found that the imbalance of psychological stress and stress systems is associated with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and erectile dysfunction (ED). CP/CPPS and ED patients scored high on psychosocial variables, and the symptom scores of lower urinary tract symptoms (LUTS) and ED were positively linked to the severity of psychological stress. The findings suggest that the autonomic nervous system (ANS) sympathovagal imbalance is associated with ED and LUTS in CP/CPPS, while the hypothalamic-pituitary-adrenal (HPA) axis activity is not.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Endocrinology & Metabolism
Amanda M. Acevedo, Michelle A. Fortier, Belinda Campos, Yohanna C. Brown, Jenna Riis
Summary: The study measured physiological responses to acute physical pain stress and found that uric acid concentrations increased following the cold pressor task, with higher levels associated with increased cortisol concentrations. The findings underline the potential role of the purinergic system in stress responses and its implications for understanding interactions with other physiological systems.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Clinical Neurology
Patrice van der Venne, Ines Murner-Lavanchy, Saskia Hoeper, Julian Koenig, Michael Kaess
Summary: This study examined the effects of NSSI severity and psychopathology on the HPA axis and ANS response to pain. The results showed that increasing NSSI severity was associated with an increased cortisol response and a decreased α-amylase level, heart rate, and heart rate variability. These findings support the use of dimensional approaches to study NSSI and its related psychopathology.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Biochemistry & Molecular Biology
Jatinder Singh, Shashidhar Ameenpur, Ruksana Ahmed, Salah Basheer, Samiya Chishti, Rosie Lawrence, Federico Fiori, Paramala Santosh
Summary: This study evaluated heart rate variability (HRV) in Rett syndrome patients and found that heart rate decreases with age and is lower at night. The sympathetic and parasympathetic indices do not change with age but are higher during the day compared to the night. The findings suggest that Rett patients are less adaptable to autonomic changes during the night.
Review
Endocrinology & Metabolism
Tobias Stalder, Sonia J. Lupien, Brigitte M. Kudielka, Emma K. Adam, Jens C. Pruessner, Stefan Wuest, Samantha Dockray, Nina Smyth, Phil Evans, Clemens Kirschbaum, Robert Miller, Mark A. Wetherell, Johannes B. Finke, Tim Klucken, Angela Clow
Summary: This article reports a critical evaluation and update of current cortisol awakening response (CAR) methodology, presenting an updated and streamlined version of the CAR consensus guidelines. A quantitative evaluation of CAR research shows limited improvement in implementing core recommendations, but evidence confirms the accuracy of the original guidelines. Furthermore, recent technological advances offer potential cost-saving methods for CAR assessment in future research.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Ophthalmology
Thomas Arendt Nielsen, Carl Uggerhoj Andersen, Henrik Vorum, Sam Riahi, Rok Sega, Asbjorn Mohr Drewes, Jesper Karmisholt, Poul Erik Jakobsen, Birgitte Brock, Christina Brock
Summary: This study aimed to investigate the effects of diabetes on sympathetic paralysis in the superior and inferior tarsal muscles and its association with the severity of diabetic retinopathy, duration of diabetes, and autonomic function. The results showed that sympathetic paralysis in the tarsal muscles was associated with the presence of proliferative diabetic retinopathy, longer duration of diabetes, and diminished autonomic function.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Article
Endocrinology & Metabolism
Jinzhou Xu, Yinwei Chen, Longjie Gu, Xiaming Liu, Jun Yang, Mingchao Li, Ke Rao, Xiyuan Dong, Shulin Yang, Bo Huang, Lei Jin, Tao Wang, Jihong Liu, Shaogang Wang, Jian Bai
Summary: Psychological stress is closely related to psychogenic erectile dysfunction (pED). Our study found that pED patients had significantly higher perceived stress compared to the control group. However, there was no significant correlation between perceived stress and erectile function. Additionally, there were significant differences in heart rate variability parameters between pED patients and the control group, but no statistical differences in cortisol variables. The interaction between sympathovagal modulation and cortisol awakening response explained significantly greater variance in perceived stress.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Emanuele Pizzo, Silvia Berrettoni, Ridhima Kaul, Daniel O. Cervantes, Valeria Di Stefano, Sudhir Jain, Jason T. Jacobson, Marcello Rota
Summary: The study found that myocardial infarction in rodents is associated with changes in heart rate variability, indicating sympathetic excitation and parasympathetic inhibition. The importance of mouse strain in evaluating autonomic function through HRV analysis was also confirmed.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Physiology
Manel Font-Farre, Ana Claudia Silva Farche, Anielle C. de Medeiros Takahashi, Myriam Guerra-Balic, Arturo Figueroa, Guillermo R. Oviedo
Summary: The study aimed to compare the cardiac autonomic modulation before, during, and after the six-minute walk test (6MWT) in older adults with and without Intellectual Disability (ID). Results showed that HRV was similar between the two groups during rest, exercise, and recovery, but the recovery HR kinetics after the 6MWT was slower in older adults with ID, possibly due to reduced post-exercise vagal rebound.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Bernhard Graessler, Milos Dordevic, Sabine Darius, Lukas Vogelmann, Fabian Herold, Corinna Langhans, Nicole Halfpaap, Irina Boeckelmann, Notger G. Mueller, Anita Hoekelmann
Summary: The study revealed that there is a decline in parasympathetic activity in cardiac autonomic control with aging. HRV analysis could help assess the normal age-related changes in cardiac autonomic control at rest and in response to cognitive demands.
Review
Neurosciences
Alexane Tournier, Michael Beacom, Jenny A. Westgate, Laura Bennet, Charles Garabedian, Austin Ugwumadu, Alistair J. Gunn, Christopher A. Lear
Summary: The interpretation of FHR patterns is crucial for monitoring fetal well-being during labor, and changes in FHR variability (FHRV) have been considered an indication of fetal compromise. However, there is a lack of systematic evidence to support this observation. This review examines the potential pathways controlling FHRV during labor-like hypoxia and suggests that the parasympathetic system becomes the sole regulator of FHRV once FHR decelerations occur.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Computer Science, Information Systems
Shu Liu, Kevin Koch, Zimu Zhou, Martin Maritsch, Xiaoxi He, Elgar Fleisch, Felix Wortmann
Summary: Driver status monitoring systems are crucial for smart cars in the future, with the focus on inferring heart rate variability (HRV) based on facial expressions. By establishing a link between facial expressions and heartbeats controlled by the autonomic nervous system, a tree-based probabilistic fusion neural network approach significantly improves HRV estimation performance. This solution relies only on a commodity camera with a lightweight algorithm, making it suitable for widespread deployment in current and future vehicles.
IEEE INTERNET OF THINGS JOURNAL
(2021)
Article
Multidisciplinary Sciences
Kazuaki Takeda, Nana Takahashi, Ei-Ichi Izawa
Summary: Recent studies have shown the important role of peripheral physiological signals in animal arousal and emotion. Specifically, heart rate has been identified as a critical signal for measuring autonomic regulation and response to biologically significant stimuli. This study examined the autonomic activity of crows during social encounters and found that the dominant and subordinate individuals displayed different patterns of autonomic responses. This research advances our understanding of the peripheral autonomic system and its interaction with the brain in eliciting emotion and arousal in socially challenging environments.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Article
Psychiatry
Frederik Beske Almstrup, Merete Nordentoft, Marie Aarrebo Jensen, Jesper Kristiansen, Tina Dam Kristensen, Christina Wenneberg, Anne Helene Garde, Louise Birkedal Glenth, Dorte Nordholm
Summary: This study investigates the association between salivary alpha amylase (SAA), heart rate variability (HRV), salivary cortisol, and cognition in individuals at ultra-high risk (UHR) of psychosis. The results show that higher levels of SAA are significantly associated with lower cognitive performance in verbal and visual learning and memory, sustained attention, working memory, and global neurocognition.
SCHIZOPHRENIA RESEARCH
(2023)
Article
Psychology, Biological
Dalbyeol Bae, Jacob J. L. Matthews, J. Jean Chen, Linda Mah
Summary: In this study, the impact of manipulating exhalation to inhalation ratio (E:I) on heart rate variability (HRV) was examined. The findings suggest that a longer exhalation relative to inhalation, without altering breathing rate, acutely increased HRV metrics, pointing towards an enhancement of cardiac vagal tone.
Letter
Neurosciences
Susann Steudte-Schmiedgen, Clemens Kirschbaum, Wei Gao, Nina Alexander, Sabine Schoenfeld, Juergen Hoyer, Tobias Stalder
BIOLOGICAL PSYCHIATRY
(2015)
Article
Psychiatry
Lars O. White, Annette M. Klein, Clemens Kirschbaum, Maria Kurz-Adam, Manfred Uhr, Bertram Mueller-Myhsok, Katrin Hoffmann, Susan Sierau, Andrea Michel, Tobias Stalder, Jenny Horlich, Jan Keil, Anna Andreas, Leonhard Resch, Martin J. Binser, Anna Costa, Elena Giourges, Eva Neudecker, Christiane Wolf, Sandra Scheuer, Marcus Ising, Kai von Klitzing
Article
Clinical Neurology
Luke A. Downey, Helen Sands, Lewis Jones, Angela Clow, Phil Evans, Tobias Stalder, Andrew C. Parrott
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
(2015)
Article
Public, Environmental & Occupational Health
Stefanie Braig, Felix Grabher, Clarissa Ntomchukwu, Frank Reister, Tobias Stalder, Clemens Kirschbaum, Dietrich Rothenbacher, Jon Genuneit
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2016)
Meeting Abstract
Endocrinology & Metabolism
Juliane Grass, Clemens Kirschbaum, Robert Miller, Wei Gao, Susann Steudte-Schmiedgen, Tobias Stalder
PSYCHONEUROENDOCRINOLOGY
(2015)
Article
Endocrinology & Metabolism
Susann Steudte-Schmiedgen, Tobias Stalder, Sabine Schoenfeld, Hans-Ulrich Wittchen, Sebastian Trautmann, Nina Alexander, Robert Miller, Clemens Kirschbaum
PSYCHONEUROENDOCRINOLOGY
(2015)
Article
Endocrinology & Metabolism
Juliane Grass, Clemens Kirschbaum, Robert Miller, Wei Gao, Susann Steudte-Schmiedgen, Tobias Stalder
PSYCHONEUROENDOCRINOLOGY
(2015)
Article
Endocrinology & Metabolism
Stefanie Braig, Felix Grabher, Clarissa Ntomchukwu, Frank Reister, Tobias Stalder, Clemens Kirschbaum, Jon Genuneit, Dietrich Rothenbacher
PSYCHONEUROENDOCRINOLOGY
(2015)
Article
Chemistry, Analytical
Wei Gao, Tobias Stalder, Clemens Kirschbaum
Article
Endocrinology & Metabolism
Nina Alexander, Franziska Rosenloecher, Lucia Dettenborn, Tobias Stalder, Julia Linke, Wolfgang Distler, Joachim Morgner, Robert Miller, Matthias Kliegel, Clemens Kirschbaum
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2016)
Review
Biochemistry & Molecular Biology
Wei Gao, Clemens Kirschbaum, Juliane Grass, Tobias Stalder
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2016)
Article
Endocrinology & Metabolism
Jessica G. Abell, Tobias Stalder, Jane E. Ferrie, Martin J. Shipley, Clemens Kirschbaum, Mika Kivimaki, Meena Kumari
PSYCHONEUROENDOCRINOLOGY
(2016)
Review
Endocrinology & Metabolism
Tobias Stalder, Clemens Kirschbaum, Brigitte M. Kudielka, Emma K. Adam, Jens C. Pruessner, Stefan Wuest, Samantha Dockray, Nina Smyth, Phil Evans, Dirk H. Hellhammer, Robert Miller, Mark A. Wetherell, Sonia J. Lupien, Angela Clow
PSYCHONEUROENDOCRINOLOGY
(2016)
Article
Psychiatry
Leigh Luella van den Heuvel, Anna Margaretha Smit, Tobias Stalder, Clemens Kirschbaum, Soraya Seedat, Robin Emsley
Summary: Individuals with schizophrenia have higher rates of metabolic syndrome (MetS) and show decreased long-term cortisol output, which may be associated with dysregulation in the hypothalamic pituitary adrenal (HPA) axis. MetS is correlated with increased hair cortisol concentrations (HCC), indicating elevated cortisol levels in schizophrenia patients.
EARLY INTERVENTION IN PSYCHIATRY
(2022)
Article
Psychology, Multidisciplinary
Anna Exner, Alla Machulska, Tobias Stalder, Tim Klucken
Summary: Individual differences in emotional coping styles can impact information processing at different stages. Repressors show a strong approach tendency towards positive stimuli, while sensitizers display a strong avoidance tendency. There were no significant group differences in attention bias and approach/avoidance bias. These findings highlight the association between emotional coping styles and information processing.
CURRENT PSYCHOLOGY
(2022)
Article
Endocrinology & Metabolism
Shanshan Xiao, Natalie C. Ebner, Amirhossein Manzouri, Tie-Qiang Li, Diana S. Cortes, Kristoffer N. T. Mansson, Hakan Fischer
Summary: The mechanisms through which intranasal oxytocin affects the brain are not fully understood, but recent research suggests that brain regions with a higher density of oxytocin receptors may play a key role. This study used resting-state fMRI to investigate the effects of intranasal oxytocin administration on connectivity between these receptor-enriched regions and other regions in the brain, and found that the effects varied depending on the age of the participants.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Lisa Haase, Antonia Vehlen, Julia Strojny, Gregor Domes
Summary: This study found no significant changes in the cortisol awakening response (CAR) over the menstrual cycle, and no significant association with variations in estradiol and progesterone. These results suggest that CAR is largely robust against hormonal variations across the menstrual cycle.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Derek Schaeuble, Tyler Wallace, Sebastian A. Pace, Shane T. Hentges, Brent Myers
Summary: Depression and cardiovascular disease are influenced by daily life stress, but the biological mechanisms behind this connection are not well understood. This study shows that the ventromedial prefrontal cortex (vmPFC) plays a role in regulating stress responses and behavior, with sex-specific effects. In males, the vmPFC-PH circuitry promotes positive motivation and reduces stress responses, while in females it elevates stress responses. This suggests that cortical regulation of stress reactivity and behavior is mediated by projections to the hypothalamus in a sex-specific manner.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Jose M. Guzman, Montana H. Boone, Gabriela L. Suarez, Colter Mitchell, Christopher S. Monk, Luke W. Hyde, Nestor L. Lopez-Duran
Summary: The COVID-19 pandemic has led to increased life stress and internalizing disorders, with a disproportionate impact on women. This study focused on the neuroendocrinology of stress-related disorders and found that women have lower cortisol responses and higher DHEA responses to stress. However, lower cortisol and higher DHEA are associated with internalizing disorders in women, while the opposite is true in men. The study also examined the relationship between COVID-related stress and internalizing symptoms and found gender differences in the association between DHEA and cortisol and internalizing outcomes. These findings suggest distinct neuroendocrine pathways for stress-related disorders in young men and women.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Meriah L. Dejoseph, Keira B. Leneman, Alyssa R. Palmer, Emily R. Padrutt, Otiti A. Mayo, Daniel Berry
Summary: Childhood and adolescence are critical periods for the development of the stress response system. This study found a modest positive relation between the adrenocortical and sympathetic systems, as well as between the adrenocortical and parasympathetic systems. The strength of these associations varied based on methodological and sociodemographic characteristics.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Qiong Xiang, Jia-Sheng Tao, Shuai Dong, Xiao-Lin Liu, Liang Yang, Li-Ni Liu, Jing Deng, Xian-Hui Li
Summary: Chronic hyperglycemia accelerates the pathological process of cognitive dysfunction, but the heterogeneity of hippocampal cells under long-term high glucose conditions is not well known. In this study, single-cell RNA sequencing was performed on diabetic mice, and distinct cell sub-clusters and important genes involved in neuroplasticity regulation were identified.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Roger Mcintosh, Hannah Hoogerwoerd, Salman S. Ahmad, Cassandra Michel, Kaitlyn Dillon, Mahendra Kumar, Gail Ironson
Summary: The study found that a 4-session guided written emotional disclosure intervention led to significant reductions in total output and concentration of epinephrine in urine for up to 6 months in individuals living with HIV. This effect was especially pronounced in women. However, there were no significant changes in norepinephrine output in urine.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Meredith Gruhn, Adam Bryant Miller, Tory A. Eisenlohr-Moul, Sophia Martin, Matthew G. Clayton, Matteo Giletta, Paul D. Hastings, Matthew K. Nock, Karen D. Rudolph, George M. Slavich, Mitchell J. Prinstein, Margaret A. Sheridan
Summary: This study investigates how early life adversity characterized by threat impacts the association between neural activity and cortisol production during emotion processing. The results suggest that threat exposure may moderate the relationship between neural activation and cortisol response.
PSYCHONEUROENDOCRINOLOGY
(2024)