Article
Oncology
Pedro Perez-Segura, Santos Enrech Frances, Ignacio Juez Martel, Maria Angeles Perez Escutia, Elena Hernandez Agudo, Leticia Leon, Guido Corradi, Helena Olivera Perez-Frade, Francisco Sanchez Escamilla, Marta Baselga Lopez, Jose Luis Baquero, Marta Redondo Delgado
Summary: The study aimed to develop and validate a tool (ADAF) to screen for anxiety and depression, and assess coping in cancer patients. Results showed that ADAF screening has adequate reliability, sensitivity and specificity. This tool can be easily applied to identify emotional and coping problems in cancer patients.
Article
Clinical Neurology
Yun Seo Jang, Na -Young Yoon, Kyungduk Hurh, Eun-Cheol Park, Min Jin Ha
Summary: This study investigated the association between the occurrence of cancer patients in the family and the depression among family members. The results showed that having cancer patients in the family was associated with an increased risk of depression in both men and women. Depressive symptoms were particularly severe in women, especially when cancer symptoms were more severe than previous surveys. Therefore, efforts to diagnose and manage depression in the families of cancer patients are needed.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Oncology
Ozlem Sonmez, Evrim Tezcanli, Elif Senocak Tasci, Hande Busra Kazanci, Ayse Altinok, Elvan Toklucu, Yusuf Tasci, Cise Aydogdu, Aysegul Bakir Aydin, Sabiha Yuce, Basak Oyan
Summary: This study investigates the psychological well-being and treatment adherence of cancer patients during the COVID-19 pandemic. The results indicate that the pandemic has increased anxiety levels, but cancer treatment remains a priority in patients' lives. Strategies should be developed to support oncology patients in coping with the pandemic and increasing their courage to avoid treatment delays.
Article
Oncology
Nathaniel E. Davis, Jonathan J. Hue, Ravi K. Kyasaram, Mohamedraed Elshami, Hallie J. Graor, Mehrdad Zarei, Karen Ji, Erryk S. Katayama, Omid Hajihassani, Alexander W. Loftus, John Shanahan, Ali Vaziri-Gohar, Luke D. Rothermel, Jordan M. Winter
Summary: The study aimed to investigate the frequency of depression or anxiety preceding a diagnosis of pancreatic cancer (PC) and its association with treatment compliance and survival. The results showed that a higher proportion of PC patients experienced depression or anxiety in the year before diagnosis compared to controls. Prediagnosis depression or anxiety was associated with reduced chemotherapy utilization and worse overall survival.
Article
Oncology
Mollie R. Canzona, David E. Victorson, Karly Murphy, Marla L. Clayman, Bonnie Patel, Nicole Puccinelli-Ortega, Thomas W. McLean, Onengiya Harry, Denisha Little-Greene, John M. Salsman
Summary: This study aimed to construct a conceptual model of FC among AYAs with cancer, identifying 13 characteristic themes grouped into four domains to guide future measurement development. The findings highlight the importance of affective experiences, communication factors, and timing factors in shaping AYAs' fertility and fertility preservation experiences.
Article
Psychology, Multidisciplinary
Rong Zhao, Hulin Liu, Jinnan Gao
Summary: This study shows a significant association between side effects of endocrine therapy and anxiety and depression in breast cancer patients. This suggests that side effects should be given more attention, and clinical interventions are needed to reduce anxiety and depression in breast cancer patients accepting endocrine therapy.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Oncology
Jessica Molinaro, Anjishnu Banerjee, Stanley Lyndon, Sarah Slocum, Carrie Danhieux-Poole, Christine Restivo-Pritzl, Ann Marie Uselmann, Lyndsey Wallace, Jennifer M. Knight
Summary: The study examined the impact of outpatient psycho-oncology treatment on distress and depression in cancer patients. Results showed significant reductions in distress and depression scores after the psycho-oncology visits, with patients no longer meeting criteria for clinically significant distress and depression. The findings support the use of psycho-oncology services in cancer patients throughout survivorship.
Article
Oncology
Shih-Hsiang Chen, Shih-Ying Chen, Shu-Chun Yang, Rong-Nan Chien, Sue-Hsien Chen, Tsuei-Ping Chu, Maiko Fujimori, Woung-Ru Tang
Summary: This study found that communication skill training based on the Japanese SHARE model can enhance the confidence and perceptions of advanced practice nurses in truth-telling about cancer. However, more rigorous studies are needed to test the effectiveness of training from the recipients' viewpoint.
Article
Oncology
Kelly M. Shaffer, Philip Chow, Jillian Glazer, Tri Le, Matthew J. Reilley, Mark J. Jameson, Lee M. Ritterband
Summary: This study demonstrated the feasibility of using EMA among cancer caregivers and found that higher caregiver depressive symptoms were related to overall higher reported negative affect and lower positive affect. The results suggest the importance of strategies to reduce negative affect and increase opportunities for positive affect in caregiving interventions.
Article
Oncology
Rodrigo Santos Vicente, Ana Rita Freitas, Ricardo Miguel Azevedo Ferreira, Sofia Parada Prada, Telma Sofia Martins, Telma Caleca Martins, Ana Duarte Mendes, Marina Miguel Vitorino, Andreia Filipa Chaves, Catarina Castro Santos, Diogo Alpuim Costa, Maria Paula Custodio, Miguel Barbosa
Summary: This study investigated patients' communication preferences and perceptions during their first medical oncology appointment. Patients highly valued their preferences regarding the dimensions of content, facilitation, and support, with a stronger emphasis on the content dimension.
Article
Oncology
Esperanza Varela-Moreno, Francisco Rivas-Ruiz, Maria Padilla-Ruiz, Julia Alcaide-Garcia, Irene Zarcos-Pedrinaci, Teresa Tellez, Nerea Fernandez-de Larrea-Baz, Marisa Bare, Amaia Bilbao, Cristina Sarasqueta, Maria Manuela Morales-Suarez-Varela, Urko Aguirre, Jose Maria Quintana, Maximino Redondo
Summary: This study analyzed the association between depressive symptoms and 5-year survival rate in colorectal cancer patients. The results showed a prevalence of depressive symptoms of 23.8% after CRC diagnosis. Depression was identified as an independent risk factor for survival, regardless of other clinical variables. Therefore, CRC patients should be screened for depressive symptoms to ensure appropriate treatment.
Article
Oncology
Kok Haw Jonathan Lim, Panagiotis Ntellas, Daniel Anderson, Lilly Simpson, Michael Braun, Marios Adamou, Jorge Barriuso, Katerina Dadouli, Jacqueline Connell, Joseph Williams, Theodora Germetaki, Deirdre Lehwald, Niall Fitzpatrick, Mark Cutting, Danielle McCool, Jurjees Hasan, Saifee Mullamitha, Kalena Marti, Mark Saunders, Konstantinos Kamposioras
Summary: This study aims to evaluate the impact of the COVID-19 pandemic on the mental health and general well-being of colorectal cancer patients through a prospective longitudinal questionnaire. Findings show that around one in four participants reported symptoms of anxiety and poor well-being, with 15% at risk of moderate to severe depression. Those who were worried about the pandemic's effect on their mental health were most at risk of anxiety, depression, and poor well-being. Screening for the mental health impact of COVID-19 on patients is crucial to prevent potential long-term detrimental consequences.
Article
Oncology
Amador Priede, Noelia Rodriguez-Perez, Fernando Hoyuela, Patricia Cordero-Andres, Olga Umaran-Alfageme, Cesar Gonzalez-Blanch
Summary: This study found that rumination is an important explanatory variable for depressive and anxiety symptoms over a five-year follow-up period, while thought suppression is only associated with anxiety symptoms. Female patients are more likely to present anxiety symptoms, but can also reduce the risk of depressive symptoms.
Article
Oncology
Eleni Arvanitou, Maria Nikoloudi, Nikolaos Tsoukalas, Efi Parpa, Kyriaki Mystakidou
Summary: Anxiety and depression are common in cancer patients and can have negative impacts on their quality of life and treatment outcomes. Recognizing the impact of demoralization and satisfaction with care is important in improving the mental well-being of cancer patients.
Article
Psychiatry
Keren Sella-Shalom, Nimrod Hertz-Palmor, Michal Braun, Eshkol Rafaeli, Reut Wertheim, Noam Pizem, Einat Shacham-Shmueli, Ilanit Hasson-Ohayon
Summary: This study applies the APIM to explore the associations between disclosure and concealment with depression and anxiety among cancer patients and their partners. Results show that disclosure is negatively associated with depression and anxiety, while concealment is positively associated. In addition, patients' self-disclosure is negatively associated with their spouses' depression. Patients' anxiety is negatively associated with similarity in all communication variables.
GENERAL HOSPITAL PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Yusuke Tsutsumi, Yasushi Tsujimoto, Aran Tajika, Kenji Omae, Tomoko Fujii, Akira Onishi, Yuki Kataoka, Morihiro Katsura, Hisashi Noma, Ethan Sahker, Edoardo Giuseppe Ostinelli, Toshi A. Furukawa
Summary: The study examines the magnitude and variability of contextual effects (PCE) in placebo-controlled trials across various interventions. The results show that subjective outcomes are influenced more by specific intervention effects compared to objective or semiobjective outcomes. The study highlights the importance of considering each PCE individually in different clinical settings.
BMJ EVIDENCE-BASED MEDICINE
(2023)
Article
Oncology
Tatsuo Akechi, Takuhiro Yamaguchi, Megumi Uchida, Fuminobu Imai, Kanae Momino, Fujika Katsuki, Naomi Sakurai, Tempei Miyaji, Tomoe Mashiko, Masaru Horikoshi, Toshi A. Furukawa, Akiyo Yoshimura, Shinji Ohno, Natsue Uehiro, Kenji Higaki, Yoshie Hasegawa, Kazuhisa Akahane, Yosuke Uchitomi, Hiroji Iwata
Summary: This study investigated the effectiveness of smartphone problem-solving therapy and behavioral activation applications in breast cancer survivors. The results showed that smartphone psychotherapy offers a promising way to reduce fear of cancer recurrence in this population.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Clinical Neurology
Rie Toyomoto, Masatsugu Sakata, Kazufumi Yoshida, Yan Luo, Yukako Nakagami, Teruhisa Uwatoko, Tomonari Shimamoto, Ethan Sahker, Aran Tajika, Hidemichi Suga, Hiroshi Ito, Michihisa Sumi, Takashi Muto, Masataka Itoi, Hiroshi Ichikawaj, Masaya Ikegawaj, Nao Shiraishi, Takafumi Watanabe, Edward R. Watkins, Hisashi Noma, Masaru Horikoshi, Taku Iwami, Toshi A. Furukawa
Summary: This study explored the prognostic factors and effect modifiers for five common components of internet-cognitive behavioural therapy (iCBT) for depression. The study found that baseline depressive symptoms and exercise habits are factors influencing the effectiveness of the self-monitoring component.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Letter
Health Care Sciences & Services
Yuki Kataoka, Masahiro Banno, Yasushi Tsujimoto, Toshi A. Furukawa
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Mathematical & Computational Biology
Tasnim Hamza, Konstantina Chalkou, Fabio Pellegrini, Jens Kuhle, Pascal Benkert, Johannes Lorscheider, Chiara Zecca, Cynthia P. Iglesias-Urrutia, Andrea Manca, Toshi A. Furukawa, Andrea Cipriani, Georgia Salanti
Summary: In network meta-analysis (NMA), all relevant evidence about health outcomes with competing treatments is synthesized. The evidence can come from randomized clinical trials (RCT) or non-randomized studies (NRS) as individual participant data (IPD) or aggregate data (AD). A suite of Bayesian NMA and network meta-regression (NMR) models are introduced to allow for cross-design and cross-format synthesis. The models integrate a three-level hierarchical model for synthesizing IPD and AD into four approaches, accounting for differences in design and risk of bias (RoB) in the evidence.
RESEARCH SYNTHESIS METHODS
(2023)
Article
Health Care Sciences & Services
Yuting Wang, Tahir Devji, Alonso Carrasco-Labra, Anila Qasim, Qiukui Hao, Elena Kum, Niveditha Devasenapathy, Madeleine T. King, Berend Terluin, Caroline B. Terwee, Michae Walsh, Toshi A. Furukawa, Yasushi Tsujimoto, Gordon H. Guyatt
Summary: The minimal important difference (MID) is the smallest change or difference that patients perceive as important to interpret patient-reported outcome measure (PROM) scores. A credibility instrument for anchor-based MID assessment typically includes a core item evaluating the correlation between the PROM and the anchor. However, many MID studies do not report this correlation. To address this, we developed an alternative construct proximity item to assess credibility when the correlation is lacking.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Health Care Sciences & Services
Tomotsugu Seki, Morio Aki, Toshi A. Furukawa, Hirotsugu Kawashima, Tomotaka Miki, Yujin Sawaki, Takaaki Ando, Kentaro Katsuragi, Takahiko Kawashima, Senkei Ueno, Takashi Miyagi, Shun'ichi Noma, Shiro Tanaka, Koji Kawakami
Summary: This study aimed to examine whether an electronic health record (EHR)-nested reminder system can help patients achieve therapeutically appropriate serum lithium levels. The study found insufficient evidence for the reminder system to increase the achievement of therapeutic serum lithium concentrations, but it did increase the number of monitoring. The EHR-based reminders may be useful for improving the quality of care for patients on lithium maintenance therapy.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Medicine, General & Internal
Yuki Furukawa, Yan Luo, Satoshi Funada, Akira Onishi, Edoardo Ostinelli, Tasnim Hamza, Toshi A. Furukawa, Yuki Kataoka
Summary: This study aimed to identify the optimal treatment duration with antibiotics for adults with community-acquired pneumonia (CAP) through a systematic review and duration-effect meta-analysis. The findings suggest that a shorter treatment duration (3-5 days) may provide the best balance between efficacy and treatment burden for treating CAP in adults who have achieved clinical stability. However, the limited number of included studies and the overall moderate-to-high risk of bias may affect the certainty of the results, highlighting the need for further research.
Article
Medicine, General & Internal
Toshi A. Furukawa, Aran Tajika, Masatsugu Sakata, Yan Luo, Rie Toyomoto, Masaru Horikoshi, Tatsuo Akechi, Norito Kawakami, Takeo Nakayama, Naoki Kondo, Shingo Fukuma, Hisashi Noma, Helen Christensen, Ronald C. Kessler, Pim Cuijpers, James M. S. Wason
Summary: This study aims to develop an iCBT platform that can adapt to the evolving internet technologies and examine the short-term and long-term efficacy of different CBT skills for depression. The study will recruit 3520 participants with subthreshold depression and approximately 1700 participants without subthreshold depression to evaluate the short-term efficacy for reducing depressive symptoms and the long-term efficacy for preventing depression in the total sample.
Article
Medicine, General & Internal
Shinji Inaba, Kazumichi Yamamoto, Tomohiro Kaga, Muhammad Wannous, Masatsugu Sakata, Osamu Yamaguchi, Toshi A. Furukawa
Summary: Despite the importance of assessing ECG interpretation skills, there is currently no established universal, standardised assessment tool for ECG interpretation. This study aims to develop a set of items for estimating competency of ECG interpretation and analyze item parameters and multidimensional latent factors to develop an assessment tool. The findings will be submitted for publication in peer-reviewed journals.
Article
Psychology, Clinical
Toshi A. Furukawa, Susumu Iwata, Masaru Horikoshi, Masatsugu Sakata, Rie Toyomoto, Yan Luo, Aran Tajika, Noriko Kudo, Eiji Aramaki
Summary: This study investigated the potential use of artificial intelligence and natural language processing to facilitate cognitive restructuring in internet cognitive-behavior therapy. The language model T5 was used to predict thoughts and feelings, and the accuracy of the predictions was validated. The results showed that correctly predicted thought-feeling pairs led to more effective reduction of negative emotions in cognitive restructuring.
COGNITIVE THERAPY AND RESEARCH
(2023)
Article
Medicine, General & Internal
Adriani Nikolakopoulou, Anna Chaimani, Toshi A. Furukawa, Theodoros Papakonstantinou, Gerta Ruecker, Guido Schwarzer
Summary: The placebo effect is the result of a participant's belief or expectation in the effectiveness of a treatment. It can play a significant role in certain conditions, particularly those with subjective symptoms. Factors such as informed consent, number of arms in a study, occurrence of adverse events, and quality of blinding can influence placebo response and introduce bias in randomized controlled trials.
BMJ EVIDENCE-BASED MEDICINE
(2023)
Article
Psychiatry
Andrea Cipriani, Soraya Seedat, Lea Milligan, Georgia Salanti, Malcolm Macleod, Janna Hastings, James Thomas, Susan Michie, Toshi A. Furukawa, David Gilbert, Karla Soares-Weiser, Carmen Moreno, Stefan Leucht, Matthias Egger, Parisa Mansoori, James M. Barker, Spyridon Siafis, Edoardo Giuseppe Ostinelli, Robert McCutcheon, Simonne Wright, Matilda Simpson, Olufisayo Elugbadebo, Virginia Chiocchia, Thomy Tonia, Rania Elgarf, Ayse Kurtulmus, Emily Sena, Ouma Simple, Niall Boyce, Sophie Chung, Anjuli Sharma, Miranda Wolpert, Jennifer Potts, Julian H. Elliott
Summary: Progress in developing novel therapies for anxiety, depression, and psychosis has been slow, and predicting effective treatments for individuals remains challenging. Understanding the mechanisms of mental health conditions, developing targeted interventions, and improving diagnosis and prediction are crucial. Living systematic reviews can enhance efficiency and reduce waste in research. The Global Alliance for Living Evidence on aNxiety, depressiOn and pSychosis (GALENOS) aims to catalog and evaluate relevant scientific research, involving both human and preclinical studies, to advance mental health science. GALENOS will also facilitate collaboration and identify key research questions, accelerating the translation of discovery science into effective interventions.
Letter
Psychiatry
Aran Tajika, Toshi A. Furukawa, Kiyomi Shinohara, Shino Kikuchi, Rie Toyomoto, Yuki Furukawa, Masami Ito, Kazufumi Yoshida, Yukiko Honda, Tomohiro Takayama, Johannes Schneider-Thoma, Stefan Leucht
Article
Psychology, Clinical
Ryuhei So, Naoki Emura, Kozue Okazaki, Sakiko Takeda, Takashi Sunami, Kohei Kitagawa, Yoshitake Takebayashi, Toshi A. Furukawa
Summary: This study compared the effects of therapist-guided internet interventions with unguided ones on gambling behavior, cognition, and stage of change. The results showed that there were no significant differences between the guided and unguided groups in terms of improvement in gambling symptoms, behavior, and stage of change.
ADDICTIVE BEHAVIORS
(2024)