Article
Geriatrics & Gerontology
Marcus K. Borges, Hans W. Jeuring, Radboud M. Marijnissen, Barbara C. van Munster, Ivan Aprahamian, Rob H. S. van den Brink, Emiel O. Hoogendijk, Richard C. Oude Voshaar
Summary: Frailty and affective disorders, such as depression and anxiety, have a bidirectional relationship. Affective disorders contribute to the progression of frailty, with the most impact seen at lower levels of frailty. The findings suggest that interventions to slow down biological aging should be targeted towards younger and middle-aged individuals, as well as non-frail older patients.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Clinical Neurology
Frank Iorfino, Ciro Marangoni, Lihong Cui, Daniel F. Hermens, Ian B. Hickie, Kathleen Ries Merikangas
Summary: The study found that anxiety-related temperamental traits show familial specificity, but these traits cannot fully explain the shared heritability between anxiety subtypes and mood disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Substance Abuse
Gamze Zengin Ispir, Mustafa Danisman, Kuebra Sezer Katar, Riza Gokcer Tulaci, Kadir Ozdel
Summary: Difficulties in emotion regulation are associated with an increased risk of recurrence in patients with OUD. Understanding these factors can inform the development of tailored treatment strategies to improve long-term outcomes. Further research is needed to explore additional factors contributing to reversion and enhance intervention and support systems for sustained recovery in OUD.
JOURNAL OF ADDICTIVE DISEASES
(2023)
Article
Clinical Neurology
Alessio Simonetti, Mario Luciano, Gaia Sampogna, Bianca Della Rocca, Emiliana Mancuso, Pasquale De Fazio, Marco Di Nicola, Giorgio Di Lorenzo, Maria Pepe, Fabio Sambataro, Maria Salvina Signorelli, Alexia Emilia Koukopoulos, Roberto Delle Chiaie, Andrea Fiorillo, Gabriele Sani
Summary: This multicentric observational study aimed to investigate the relationship between affective temperaments and bipolar disorder (BD) or major depressive disorder (MDD), as well as their influence on the severity and course of the diseases. The results revealed that specific affective temperaments were associated with certain disease characteristics. Evaluating affective temperaments may contribute to a better understanding of mood disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Alp Ucok, Begum Karakas, Olcay Senay Sahin
Summary: Formal thought disorder has three factors, each with a unique relationship with cognition and functioning in patients with schizophrenia. The findings highlight the complex relationship between formal thought disorder and functional outcomes in schizophrenia patients.
PSYCHIATRY RESEARCH
(2021)
Article
Medicine, Research & Experimental
Hye Jun Kim, Seogsong Jeong, Kyung Jin Roh, Yun Hwan Oh, Michelle J. Suh
Summary: A large-scale epidemiological study in Korean older adults found that hearing impairment is independently associated with a higher risk of new-onset depression, with a significant interaction among age, hearing impairment, and the risk of depression.
Article
Psychiatry
Hang-Ju Yang, Wan-Ju Cheng, Mi-Chun Hsiao, Sheng-Che Huang, Tomohide Kubo, Liang-Wen Hang, Wei-Sheng Lee
Summary: This study examined the association between rest-activity rhythm changes and mood symptoms and attention in patients with depressive disorder. The results showed that changes in rest-activity rhythm were associated with depressive symptom severity and attention.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Neurosciences
Emmi Pentikainen, Lilli Kimppa, Anni Pitkaniemi, Outi Lahti, Teppo Sarkamo
Summary: This study conducted a 2-year follow-up study and found that older adult choir singers showed sustained enhancement in verbal flexibility, but the effects on other verbal skills and quality of life were unclear.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Yiheng Tu, Yuqi Zhang, Yu Li, Qing Zhao, Yanzhi Bi, Xuejing Lu, Yazhuo Kong, Li Wang, Zhijie Lu, Li Hu
Summary: The study suggests that COVID-19 survivors may experience deteriorations in PTSS, with PCL-5 scores positively correlated with duration after discharge and potential changes in brain structural volumes in bilateral hippocampus and amygdala.
MOLECULAR PSYCHIATRY
(2021)
Article
Clinical Neurology
Hanne Lie Kjaerstad, Thea Haldorsen, Maj Vinberg, Lars Vedel Kessing, Kamilla Woznica Miskowiak
Summary: This study found that impairments in both emotional and non-emotional cognition are associated with bipolar disorder (BD). There is a lack of research investigating cognitive predictors of prognosis in BD patients. The study showed that cognitive performance at baseline is associated with recurrence and duration of (hypo)manic and depressive episodes in patients with BD over a 16-month follow-up period. Therefore, early prophylactic strategies targeting cognitive impairments may improve the resilience and course of illness in recently diagnosed patients with BD.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Pediatrics
Jenny McDonald, Susan Milne, Anne Masi, Jerzy Zieba, Valsamma Eapen
Summary: The study found that all children were confirmed to have ASD at follow-up, with improvements in adaptive skills. Early developmental and adaptive assessments reliably predicted later educational support needs, cognitive and adaptive function.
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2021)
Article
Clinical Neurology
Hanne Lie Kjaerstad, Kristine Sohol, Maj Vinberg, Lars Vedel Kessing, Kamilla Woznica Miskowiak
Summary: Cognitive impairments are present in remitted patients with bipolar disorder (BD) and their unaffected relatives (UR) compared to healthy controls (HC). However, the temporal course of cognition and whether it is marked by neuroprogressive changes are still unclear. In a prospective study, newly diagnosed patients with BD, UR, and HC were assessed using a comprehensive cognitive battery at baseline and 16-month follow-up. There was no evidence of trajectory differences in neurocognition and emotional cognition between BD patients, UR, and HC. BD patients showed stable impairments in global neurocognitive functioning over time, while UR had deficits in working memory and executive function. Poorer neurocognition and positive emotion regulation were associated with sub-syndromal symptoms and functional impairments.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Psychiatry
Elie G. Karam, Dahlia Saab, Salam Jabbour, Georges E. Karam, Elie Hantouche, Jules Angst
Summary: The aim of this study is to evaluate the role of individual affective temperaments as clinical predictors of bipolarity. A total of 1723 adult outpatients were assessed using various tools, and the results showed that irritable temperament is a consistent predictor of bipolar I and II disorders. Cyclothymic temperament also played a strong role in bipolarity, especially in bipolar II and substance-induced bipolarity, while hyperthymic temperament had no role in bipolar I or II disorder.
EUROPEAN PSYCHIATRY
(2023)
Article
Clinical Neurology
Mette Bagge Jensen, Hanne Lie Kjaerstad, Klara Coello, Sharleny Stanislaus, Sigurd Melbye, Kimie Ormstrup Sletved, Maj Vinberg, Lars Vedel Kessing, Kamilla Woznica Miskowiak
Summary: The study found no significant differences in cognitive profiles between recently diagnosed BD-I and BD-II, indicating that neither affective nor non-affective cognition are indicative of BD subtype.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Multidisciplinary
Nina Dalkner, Eva Fleischmann, Frederike T. Fellendorf, Jolana Wagner-Skacel, Elena M. D. Schoenthaler, Susanne Bengesser, Alfred Haeussl, Sophie Tietz, Adelina Tmava-Berisha, Melanie Lenger, Eva Z. Reininghaus
Summary: The study found that individuals with affective disorders had more uncertainty and experienced fewer positive emotions in their beliefs about COVID-19 vaccination compared to healthy controls, despite there being no difference in vaccination status between the two groups.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Nutrition & Dietetics
Aline Mendes, Christine Serratrice, Francois R. Herrmann, Gabriel Gold, Christophe E. Graf, Dina Zekry, Laurence Genton
Summary: Nutritional risk at admission is associated with prolonged length of hospital stay (LOS) but not with mortality in older patients with COVID-19.
CLINICAL NUTRITION
(2022)
Article
Medicine, Research & Experimental
Samanta Buchholzer, Frederic Faure, Livia Tcheremissinoff, Francois R. Herrmann, Tommaso Lombardi, Siu-Kwan Ng, Jean-Michel Lopez, Urs Borner, Robert L. Witt, Robert Irvine, Olivier Abboud, Claudio R. Cernea, Shirish Ghan, Takeshi Matsunobu, Zahoor Ahmad, Randall Morton, Aleksandar Anicin, Emad A. Magdy, Rashid Al Abri, Iordanis Konstantinidis, Pasquale Capaccio, Hila Klein, Vincent Vander Poorten, Davide Lombardi, Bernard Lyons, Hussain Al Rand, George Liao, Jeong K. Kim, Sethu Subha, Richard Y. -X. Su, Chin-Hui Su, Franciscus Boselie, Raphael Andre, Jorg D. Seebach, Francis Marchal
Summary: This study aimed to establish and validate a novel questionnaire to document symptoms of xerostomia and sialadenitis, including their impact on quality of life. The validation of the questionnaire was conducted on patients with various salivary pathologies and healthy volunteers. The results showed good internal coherence of the questionnaire items, with the recommended use of the Q10 version for more accurate international use.
Article
Neurosciences
Panteleimon Giannakopoulos, Cristelle Rodriguez, Marie-Louise Montandon, Valentina Garibotto, Sven Haller, Francois R. Herrmann
Summary: This study examines the impact of personality on Alzheimer's disease (AD) and vascular imaging markers. The results show that high levels of conscientiousness and openness are positively associated with AD-signature MRI markers, while higher extraversion levels are associated with an increased number of cortical microbleeds.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Psychiatry
Isabella D'Orta, Francois R. Herrmann, Panteleimon Giannakopoulos
Summary: There are significant sociodemographic and clinical differences between offenders receiving court-ordered treatments and regular prison inmates. In the Swiss penitentiary system, court-ordered treatment patients are less exposed to acculturation issues and have a higher prevalence of personality and psychotic disorders.
ANNALS OF GENERAL PSYCHIATRY
(2022)
Article
Nutrition & Dietetics
Guillaume T. Duval, Anne-Marie Schott, Dolores Sanchez-Rodriguez, Francois R. Herrmann, Cedric Annweiler
Summary: The study suggests that older women born in the summer to early fall months have higher muscle mass and strength.
Article
Medicine, General & Internal
Andrea Aguglia, Giovanni Pietro Corsini, Alessandra Costanza, Andrea Berti, Edoardo Bruno, Andrea Escelsior, James Sanvi, Alice Trabucco, Eleonora Vai, Andrea Amerio, Gianluca Serafini, Mario Amore
Summary: The aim of this study is to identify the main sociodemographic and clinical correlates associated with frequent service users (FSUs) in an Italian psychiatric emergency department. The results showed that FSUs were more likely to be single, younger, with an earlier onset, and have a longer length of hospitalisation compared to non-FSUs. They were also more prone to bipolar disorder, cluster B personality disorder, substance use disorder, and non-suicidal self-injuries. Furthermore, FSUs were more likely to be discharged against medical advice or have escape attempts from the psychiatric ward.
Review
Neurosciences
Andrea Amerio, Eleonora Vai, Edoardo Bruno, Alessandra Costanza, Andrea Escelsior, Anna Odone, Domenico De Berardis, Andrea Aguglia, Gianluca Serafini, Mario Amore, Seyyed Nassir Ghaemi
Summary: Despite the pandemic triggering a wave of research, few studies have looked into the impact of COVID-19 on Italy's community-based mental health care system. This study aimed to summarize existing evidence and also drew from daily clinical practice. Despite reduced hospital care, community mental health centers promoted continuity of care through teleconsultation, leading to lower risk of deterioration and hospitalization for patients. This model received satisfaction from both patients and mental health workers.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Article
Psychology, Clinical
Vasileios Chytas, Alessandra Costanza, Viridiana Mazzola, Christophe Luthy, Guido Bondolfi, Christine Cedraschi
Summary: The literature emphasizes that patients with chronic pain are at a high risk of suicidal behavior. The aim of this study was to investigate the relationship between demoralization and suicidal ideation in these patients and to determine whether demoralization can occur independently of depression. The findings showed a significant correlation between demoralization and suicidal ideation, as well as a strong positive correlation between demoralization and depressive symptoms. However, it was difficult to differentiate between depression and demoralization as they both exhibited strong positive correlations with suicidal thoughts.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2023)
Article
Dentistry, Oral Surgery & Medicine
Murali Srinivasan, Stephan Duong, Veronique Trombert, Nicole Kalberer, Dina Zekry, Francois R. Herrmann, Joris Delavy, Gabriel Gold, Frauke Muller
Summary: The study aimed to validate a novel screening test for cognitive and functional decline in older patients rehabilitated with complete removable dental prostheses (CRDPs). Edentate old in-patients rehabilitated with CRDPs were included in the study. Participants were requested to remove and reinsert their prostheses in the appropriate jaws, and the results were associated with the participants' MMSE score, FIM, age, and sex. The prosthesis presentation test (PPT) was found to be associated with the FIM and its cognitive sub-sets.
Article
Medicine, General & Internal
Andrea Aguglia, Antimo Natale, Benedetta Conio, Clio Franziska De Michiel, Alessio Lechiara, Fabrizio Pastorino, Laura Fusar-Poli, Alessandra Costanza, Andrea Amerio, Mario Amore, Gianluca Serafini
Summary: This study investigated the relationship between chronotype and cardiometabolic parameters in patients with bipolar disorder. The results showed that patients with an eveningness chronotype had higher body mass index, total and low-density lipoprotein cholesterol compared to those with an intermediate or morning chronotype. Furthermore, the atherogenic coefficient and Castelli risk index were found to be higher in bipolar patients with an evening chronotype. Investigating the relationship between chronotype and obesity and cardiovascular risk is important for improving clinical and therapeutic approaches and reducing mortality in bipolar disorder.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Andrea Aguglia, Giovanni Pietro Corsini, Isabella Berardelli, Andrea Berti, Benedetta Conio, Nicolo Garbarino, Giovanni Battista Gnecco, Caterina Magni, Enrico Venturini, Alessandra Costanza, Andrea Amerio, Mario Amore, Gianluca Serafini
Summary: This study aimed to estimate the prevalence of mechanical restraint (MR) in an Italian psychiatric unit and identify the associated characteristics. The results showed that MR was more prevalent among males, younger individuals, those who were single and migrants, as well as patients with other diagnoses, comorbid illicit substance use, aggressive behaviors, and involuntary admission. Additionally, patients who underwent MR were taking fewer psychiatric medications.
MEDICINA-LITHUANIA
(2023)
Article
Health Care Sciences & Services
Vasileios Chytas, Alessandra Costanza, Viridiana Mazzola, Christophe Luthy, Vasiliki Galani, Guido Bondolfi, Christine Cedraschi
Summary: The presence of Meaning in Life (MiL) has a potential protective effect against suicidal ideation (SI), while the search for MiL is also a possible resilience factor. Patients with low presence-low search profile had higher scores of SI. These findings provide guidance for psychotherapeutic interventions for chronic pain patients.
JMIR FORMATIVE RESEARCH
(2022)
Meeting Abstract
Endocrinology & Metabolism
Melany Hars, Francois Herrmann, Thierry Chevalley, Serge Ferrari, Gabriel Gold, Rene Rizzoli, Patrik Vuilleumier, Andrea Trombetti
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Panteleimon Giannakopoulos, Marie-Louise Montandon, Francois R. Herrmann, Dennis Hedderich, Christian Gaser, Elias Kellner, Cristelle Rodriguez, Sven Haller
Summary: Novel quantitative AI-based volumetric scores provide additional value in predicting subsequent cognitive decline in elderly controls compared to established visual MRI markers.
EUROPEAN RADIOLOGY
(2022)
Article
Psychology, Multidisciplinary
Michalina Radomska, Joao Flores Alves dos Santos, Kerstin Weber, Marc Baertschi, Pierre R. Burkhard, Francois Herrmann, Sanaa Belayachi, Nicolas Favez, Alessandra Canuto
Summary: This study developed a questionnaire called Preoperative Hope and Expectations Questionnaire (PHEQ) to assess cognitive representations of surgery outcomes. The results showed that PHEQ has satisfactory psychometric properties and can be considered as a reliable instrument for research and clinical practice.