Article
Psychology, Clinical
Oscar W. H. Wong, Ran Barzilay, Angela M. W. Lam, Sandra Chan, Monica E. Calkins, Raquel E. Gur, Ruben C. Gur
Summary: Executive function is uniquely associated with the severity of comorbid psychopathology in individuals with autism spectrum disorder (ASD), and could be a potential target for interventions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Biology
Pinelopi S. Stavrinou, George Aphamis, Marios Pantzaris, Giorgos K. Sakkas, Christoforos D. Giannaki
Summary: The study found that functional capacity levels were correlated with cognitive and executive function, quality of life, fatigue levels, and sleep quality in older adults. Functional capacity partially mediated the effects of age on cognitive and executive function.
Article
Psychology, Clinical
Dan Foti, Greg Perlman, Evelyn J. Bromet, Philip D. Harvey, Greg Hajcak, Daniel H. Mathalon, Roman Kotov
Summary: This study examined the relationship between neural measures of performance monitoring and executive function, symptoms, and functioning in individuals with psychotic disorders. The results showed that reduced error-related negativity and error positivity were associated with impaired executive function, negative symptom severity, and poor real-world functioning in the clinical cohort. Multiple potential pathways were identified, suggesting a transdiagnostic model of psychotic disorders where poor performance monitoring contributes to impaired executive function, negative symptoms, and poor functioning.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Annelies van't Westeinde, Sara Strom, Tatja Hirvikoski, Per Dahlqvist, Jeanette Wahlberg, Anton Gezelius, Olle Kampe, Sophie Bensing, Svetlana Lajic
Summary: The study found that young adult female patients with autoimmune Addison's disease (AAD) experience problems with executive functions in daily life, despite performing normally in cognitive tests. Coping with mental fatigue and optimizing pharmacotherapy may be important factors to provide timely support for patients.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Clinical Neurology
Jennifer Bogert, Hany Rofael, Kenneth Mosca, Rachel Ochs Ross, Geert Callaerts, Daniel Wang, Judith Jaeger, Vaibhav A. Narayan, Wayne C. Drevets, Randall L. Morrison
Summary: The study analyzed the performance validity and test-retest reliability of the iPad-administered cognitive test battery, ReVeRe.D, in MDD and found it to have good concurrent validity and test-retest reliability. The study included stable participants who had responded to oral antidepressant treatment and was limited to English-speaking, white, college-educated women, suggesting the need for further research with a broader demographic representation.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neurosciences
Nina Dalkner, Susanne A. Bengesser, Armin Birner, Frederike T. Fellendorf, Eva Fleischmann, Katja Grossschaedl, Melanie Lenger, Alexander Maget, Martina Platzer, Robert Queissner, Elena Schonthaler, Adelina Tmava-Berisha, Eva Z. Reininghaus
Summary: The study revealed a higher prevalence of metabolic syndrome in patients with bipolar disorder and impaired executive function in those with comorbid metabolic syndrome. However, no effects of metabolic syndrome were found in attention/processing speed and verbal learning/memory.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Cell Biology
Samantha Marshall, Raphael Gabiazon, Priyanka Persaud, Lindsay S. Nagamatsu
Summary: Impaired cognition is a known risk factor for falls in older adults. This systematic review examines the use of functional neuroimaging techniques to investigate the association between falls and cognition in seniors. Nine studies were included, showing consistent evidence that cognition, particularly visual attention and executive function, is associated with falls/falls risk. Specific brain regions and networks may be implicated in falls/falls risk. Future studies should be prospective, long-term, and use standardized outcome measures, and mobile neuroimaging techniques may provide additional insights.
AGEING RESEARCH REVIEWS
(2023)
Article
Geriatrics & Gerontology
Jessica Salles Henrique, Pedro Luiz Garcia Braga, Sandro Soares de Almeida, Nathalia Santanna Petraconi Nunes, Izabelle Dias Benfato, Ricardo Mario Arida, Camila Aparecida Machado de Oliveira, Sergio Gomes da Silva
Summary: This study investigated the impact of ACTN-3 gene polymorphism on functional fitness and cognitive capacity in the elderly. The results showed a positive effect of ACTN-3 gene polymorphism on executive function, but no effect on functional fitness.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Clinical Neurology
Keera N. Fishman, Andrea R. Ashbaugh, Richard H. Swartz
Summary: The study found that goal setting had a positive impact on cognitive function after stroke, particularly in executive function, attention/working memory, and verbal learning. This suggests that more than 3 months after stroke, vascular cognitive impairment is not a fixed deficit, and motivation may play a role in improvement.
Article
Clinical Neurology
Damiano Mistri, Laura Cacciaguerra, Loredana Storelli, Alessandro Meani, Claudio Cordani, Maria A. Rocca, Massimo Filippi
Summary: This study found an association between cognition and motor function in patients with multiple sclerosis (MS), which goes beyond the effect of structural brain damage. Specifically, deficits in information processing speed and executive function were found to contribute to hand motor dysfunction. These findings suggest the importance of integrating motor and cognitive assessment in clinical settings.
JOURNAL OF NEUROLOGY
(2022)
Article
Clinical Neurology
Isabelle Rouch, Jean-Michel Dorey, Marie-Pierre F. Strippoli, Mehdi Gholam, Pedro Marques-Vidal, Bernard Laurent, Armin von Gunten, Martin Preisig
Summary: This study prospectively assessed the association between cognitive functioning and the occurrence of chronic pain in older community dwellers. Results suggest that patients with inhibitory deficits may be at higher risk of developing chronic pain in the presence of painful events. A cognitive assessment should be recommended to identify and manage frail patients in these situations.
Article
Medicine, General & Internal
Anne E. Brandt, Torun G. Finnanger, Ruth E. Hypher, Torstein B. Ro, Eva Skovlund, Stein Andersson, Kari Risnes, Jan Stubberud
Summary: This study evaluated interventions for executive dysfunction after pediatric acquired brain injury and found that metacognitive training did not show additional effectiveness compared to psychoeducative control. Both interventions were well-tolerated and demonstrated distinct improvements at different levels of executive function assessment.
Article
Psychology, Clinical
P. Fuentes-Claramonte, L. Lopez-Araquistain, S. Sarro, B. Sans-Sansa, J. Ortiz-Gil, T. Maristany, R. Salvador, P. J. McKenna, E. Pomarol-Clotet
Summary: The study provides functional imaging evidence supporting the view that FTD in schizophrenia may involve impaired executive/frontal function, particularly related to alogia. The correlations were found in areas including the inferior frontal cortex, dorsolateral prefrontal cortex, temporal cortex, basal ganglia, and thalamus.
PSYCHOLOGICAL MEDICINE
(2021)
Review
Clinical Neurology
Serenax Giomi, Francesca Siri, Adele Ferro, Chiara Moltrasio, Mayowa Ariyo, Giuseppe Delvecchio, Paolo Brambilla
Summary: While most studies suggest that panic disorder (PD) patients do not show significant alterations in executive functioning (EF), some do find deficits in certain domains. Further research with standardized methodologies and gold standard assessment of EF is needed to conclusively determine the involvement of EF in PD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Susanne M. van der Veen, Robert A. Perera, Laura Manning-Franke, Amma A. Agyemang, Karen Skop, Scott R. Sponheim, Elisabeth A. Wilde, Alexander Stamenkovic, James S. Thomas, William C. Walker
Summary: Among patients with mild traumatic brain injury (mTBI), postural instability often persists chronically. Reduced executive function (EF) may explain this phenomenon, as it affects the processing and interpretation of sensory information. Our study aimed to investigate if specific tests of EF could predict balance function in individuals with a history of chronic mTBI.
FRONTIERS IN NEUROLOGY
(2023)
Article
Anesthesiology
Linda Hermans, Jo Nijs, Patrick Calders, Luc De Clerck, Greta Moorkens, Guy Hans, Sofie Grosemans, Tine Roman de Mettelinge, Joanna Tuynman, Mira Meeus
Review
Clinical Neurology
Dries Bleys, Patrick Luyten, Bart Soenens, Stephan Claes
JOURNAL OF AFFECTIVE DISORDERS
(2018)
Article
Neurosciences
Linda van Diermen, Didier Schrijvers, Olivia Cools, Tom K. Birkenhager, Erik Fransen, Bernard G. C. Sabbe
NEUROPSYCHOBIOLOGY
(2018)
Review
Psychiatry
Laura L. M. Cassiers, Bernard G. C. Sabbe, Lianne Schmaal, Dick J. Veltman, Brenda W. J. H. Penninx, Filip Van den Eede
FRONTIERS IN PSYCHIATRY
(2018)
Article
Pharmacology & Pharmacy
Andrea Polli, Jessica Van Oosterwijck, Jo Nijs, Uros Marusic, Inge De Wandele, Lorna Paul, Mira Meeus, Greta Moorkens, Luc Lambrecht, Kelly Ickmans
CLINICAL THERAPEUTICS
(2019)
Correction
Psychiatry
Maud De Venter, Jela Illegems, Rita Van Royen, Greta Moorkens, Bernard G. C. Sabbe, Filip Van den Eede
COMPREHENSIVE PSYCHIATRY
(2019)
Article
Clinical Neurology
Peter Niemegeers, Peter de Boer, Jeroen Schuermans, Glenn J. H. Dumont, Violette Coppens, Kurt Spittaels, Stephan Claes, Bernard G. C. Sabbe, Manuel Morrens
JOURNAL OF AFFECTIVE DISORDERS
(2019)
Article
Clinical Neurology
Petra V. Viher, Lise Docx, Wim Van Hecke, Paul M. Parizel, Bernard Sabbe, Andrea Federspiel, Sebastian Walther, Manuel Morrens
PSYCHIATRY RESEARCH-NEUROIMAGING
(2019)
Article
Neurosciences
Kaat Hebbrecht, Mirella Stuivenga, Tom Birkenhager, Roos C. van der Mast, Bernard Sabbe, Erik J. Giltay
NEUROPSYCHOBIOLOGY
(2020)
Article
Neurosciences
Laura L. M. Cassiers, Peter Niemegeers, Erik Fransen, Manuel Morrens, Peter De Boer, Luc Van Nueten, Stephan Claes, Bernard G. C. Sabbe, Filip Van den Eede
Article
Psychiatry
Maud De Venter, Bernet M. Elzinga, Filip Van den Eede, Kristien Wouters, Guido F. Van Hal, Dick J. Veltman, Bernard G. C. Sabbe, Brenda W. J. H. Penninx
EUROPEAN PSYCHIATRY
(2020)
Article
Psychiatry
Maud De Venter, Jela Illegems, Rita Van Royen, Bernard G. C. Sabbe, Greta Moorkens, Filip Van den Eede
FRONTIERS IN PSYCHIATRY
(2020)
Article
Health Care Sciences & Services
Alex Wilhelmus Jacobus van Kraaij, Giuseppina Schiavone, Erika Lutin, Stephan Claes, Chris Van Hoof
JOURNAL OF MEDICAL INTERNET RESEARCH
(2020)
Article
Neurosciences
Claudia Cornelis, Livia J. De Picker, Violette Coppens, Anne Morsel, Maarten Timmers, Glenn Dumont, Bernard G. C. Sabbe, Manuel Morrens, Wouter Hulstijn
Summary: The cognitive dysmetria hypothesis suggests disrupted communication between the cerebellum and cerebral cortex in schizophrenia, leading to sensorimotor and cognitive symptoms. This study found that sensorimotor adaptation is reduced in schizophrenia patients compared to age-matched and elderly controls. Patients with schizophrenia showed impairments in both explicit and implicit components of sensorimotor adaptation learning.
NEUROPSYCHOBIOLOGY
(2022)
Article
Psychology, Clinical
Martijn Van Heel, Patricia Bijttebier, Stephan Claes, Hilde Colpin, Luc Goossens, Wim Van Den Noortgate, Karine Verschueren, Karla Van Leeuwen