Journal
PSYCHIATRY RESEARCH
Volume 161, Issue 3, Pages 336-338Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2006.10.005
Keywords
NQO1 Pro187Ser polymorphism; MnSOD Ala-9Val; Interaction polymorphism; Tardive dyskinesia
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Funding
- Korea Research Foundation [KRF-2004-003-E00145]
- National Research Foundation of Korea [2004-003-E00145] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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This study investigated whether there was an interaction between the NQO1 Pro187Ser and MnSOD Ala-9Val gene polymorphisms in the development or tardive dyskinesia (TD). The combined genotypes of T/T in NQO1 Pro187Ser and Val/Val in MnSOD Ala-9Val polymorphisms were found to be independently associated with a significantly higher risk of TD. However, further adequately powered studies will be needed to confirm these preliminary Findings. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
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